JP2001521002A - 脳の代謝機能不全のための栄養補充剤 - Google Patents
脳の代謝機能不全のための栄養補充剤Info
- Publication number
- JP2001521002A JP2001521002A JP2000517723A JP2000517723A JP2001521002A JP 2001521002 A JP2001521002 A JP 2001521002A JP 2000517723 A JP2000517723 A JP 2000517723A JP 2000517723 A JP2000517723 A JP 2000517723A JP 2001521002 A JP2001521002 A JP 2001521002A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- pharmaceutical composition
- group
- mixtures
- krebs cycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6316597P | 1997-10-24 | 1997-10-24 | |
| US60/063,165 | 1997-10-24 | ||
| PCT/US1998/018120 WO1999021565A1 (en) | 1997-10-24 | 1998-09-01 | Nutritional supplement for cerebral metabolic insufficiencies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010106232A Division JP2010189432A (ja) | 1997-10-24 | 2010-05-06 | 脳の代謝機能不全のための栄養補充剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001521002A true JP2001521002A (ja) | 2001-11-06 |
| JP2001521002A5 JP2001521002A5 (enExample) | 2010-01-21 |
Family
ID=22047375
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000517723A Withdrawn JP2001521002A (ja) | 1997-10-24 | 1998-09-01 | 脳の代謝機能不全のための栄養補充剤 |
| JP2010106232A Pending JP2010189432A (ja) | 1997-10-24 | 2010-05-06 | 脳の代謝機能不全のための栄養補充剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010106232A Pending JP2010189432A (ja) | 1997-10-24 | 2010-05-06 | 脳の代謝機能不全のための栄養補充剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6537969B1 (enExample) |
| EP (1) | EP1032403B1 (enExample) |
| JP (2) | JP2001521002A (enExample) |
| AT (1) | ATE555780T1 (enExample) |
| AU (1) | AU760140B2 (enExample) |
| CA (1) | CA2306875C (enExample) |
| WO (1) | WO1999021565A1 (enExample) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003068215A1 (fr) * | 2002-02-14 | 2003-08-21 | Ajinomoto Co., Inc. | Médicaments pour maladies mitochondriales |
| JP2007023010A (ja) * | 2005-07-19 | 2007-02-01 | Toshiro Azegami | 閉経後のホルモンバランス調整及びパーキンソン症の予防改善目的の経口組成物 |
| JP2007529408A (ja) * | 2003-07-01 | 2007-10-25 | エッセンティス アクティエボラーグ | 栄養失調及び高血漿グルコース状態を治療するためのアルファ−ケトグルタル酸の使用 |
| JPWO2006025247A1 (ja) * | 2004-08-30 | 2008-05-08 | 株式会社カネカ | ミトコンドリア賦活剤 |
| JP2008524256A (ja) * | 2004-12-17 | 2008-07-10 | アラン ビー. キャッシュ | 寿命を拡大させ、かつ加齢関連疾患の発症を遅らせるための方法 |
| JP2011225609A (ja) * | 2003-07-01 | 2011-11-10 | Essentys Ab | 栄養失調及び高血漿グルコース状態を治療するためのアルファ−ケトグルタル酸の使用 |
| JP2012107023A (ja) * | 2004-12-21 | 2012-06-07 | Critical Care Connections Inc | 治療用栄養組成物又は組合せ、及びそれらの使用方法 |
| JP2017519020A (ja) * | 2014-07-03 | 2017-07-13 | メディカル リサーチ カウンシルMedical Research Council | コハク酸脱水素酵素阻害剤(SDHi’s) |
| JP2018030795A (ja) * | 2016-08-23 | 2018-03-01 | 株式会社Hbcフナト | 脳機能改善組成物 |
| JP2020528400A (ja) * | 2017-07-28 | 2020-09-24 | プロフェッショナル ダイエテティクス インターナショナル エス.アール.エル. | ミトコンドリア機能障害関連疾患の治療に使用するための、アミノ酸を備える組成物 |
| JP2022504771A (ja) * | 2018-10-24 | 2022-01-13 | ポンセ デ レオン ヘルス デシグネイテッド アクティビティ カンパニー | 健康寿命延長を目的とするニコチンアミドリボシド組成物 |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2327404A1 (en) * | 1994-11-08 | 2011-06-01 | Avicena Group, Inc. | Use of creatine or creatine analogs for the treatment of diseases of the nervous system |
| US20050245612A1 (en) * | 2004-05-03 | 2005-11-03 | Blass John P | Pharmaceutical compositions for metabolic insufficiencies |
| AU759467B2 (en) * | 1998-04-02 | 2003-04-17 | Avicena Group, Inc. | Compositions containing a combination of a creatine compound and a second agent |
| US20060128671A1 (en) * | 1998-04-02 | 2006-06-15 | The General Hospital Corporation | Compositions containing a combination of a creatine compound and a second agent |
| DE19853487A1 (de) | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
| DE19932197A1 (de) * | 1999-07-09 | 2001-01-18 | Neudecker Birgit | Topisch anzuwendendes Mittel mit schützender und regenerativer Wirkung |
| US6689753B1 (en) * | 1999-11-05 | 2004-02-10 | Axonyx, Inc. | β sheet breaker peptide analogs that inhibit β pleated sheet formation in amyloid β-peptide |
| DE10000577A1 (de) | 2000-01-10 | 2001-07-26 | Fumapharm Ag Muri | Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten |
| GB2348371B (en) * | 2000-03-14 | 2001-04-04 | Soares Da Silva Patricio | Compositions comprising blockers of L-DOPA renal cell transfer for the treatment of Parkinson's disease |
| US7226916B1 (en) | 2000-05-08 | 2007-06-05 | N.V. Nutricia | Preparation for the prevention and/or treatment of vascular disorders |
| US7208180B2 (en) | 2000-05-08 | 2007-04-24 | N.V. Nutricia | Method and preparation for the preventing and/or treating vascular disorders and secondary disorders associated therewith |
| SK288238B6 (sk) | 2001-01-12 | 2015-01-07 | Fumapharm Ag | Amidy kyseliny fumarovej |
| UA76444C2 (en) | 2001-02-14 | 2006-08-15 | Composition of biochemical compounds involved in bioenergy metabolism of cells and method of its use in prevention and therapy of diseases | |
| EP1455826A2 (en) * | 2001-12-21 | 2004-09-15 | Ilex Oncology, Inc. | Combination comprising anti-cd52 antibodies and other therapeutic agents for treatment of multiple sclerosis |
| EP1820806A1 (en) * | 2006-02-16 | 2007-08-22 | Crossbeta Biosciences B.V. | Affinity regions |
| DE10217314A1 (de) * | 2002-04-18 | 2003-11-13 | Fumapharm Ag Muri | Carbocyclische und Oxacarboncyclische Fumarsäure-Oligomere |
| AU2003238872A1 (en) * | 2002-06-04 | 2003-12-19 | Avicena Group, Inc. | Methods of treating cognitive dysfunction by modulating brain energy metabolism |
| US20070003552A1 (en) * | 2002-07-09 | 2007-01-04 | Gebbink Martijn F B | Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation |
| EP1380290A1 (en) * | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-beta structure pathway and its therapeutic relevance |
| CA2494348C (en) * | 2002-08-01 | 2014-04-08 | Yeda Research And Development Co. Ltd. | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels |
| US7977049B2 (en) * | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| WO2004028468A2 (en) * | 2002-09-27 | 2004-04-08 | Children's Medical Center Corporation | Methods and compositions for treatment of neurological disorder |
| EP2236131A3 (en) * | 2003-07-01 | 2011-03-02 | President and Fellows of Harvard College | Sirt1 modulators for manipulating cell/organism lifespan/stress response |
| US20060025337A1 (en) * | 2003-07-01 | 2006-02-02 | President And Fellows Of Harvard College | Sirtuin related therapeutics and diagnostics for neurodegenerative diseases |
| EP1913942B1 (en) | 2003-09-09 | 2009-11-11 | Biogen Idec International GmbH | The use of fumaric acid derivatives for inhibition of PGF-induced thymidine uptake of bronchial smooth muscle cells and for inhibition of bronchial smooth cells proliferation |
| US20050171027A1 (en) | 2003-12-29 | 2005-08-04 | President And Fellows Of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
| US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| WO2006007411A2 (en) * | 2004-06-16 | 2006-01-19 | President And Fellows Of Harvard College | Methods and compositions for modulating bax-mediated apoptosis |
| PL368572A1 (en) * | 2004-06-17 | 2005-12-27 | Sgp & Sons Ab | Pharmaceutical compound for prevention and therapy of increased level of cholesterol, ldl and triglycerides as well as application of the pharmaceutical compound as an agent acting against atherosclerosis and used in circulatory system affections |
| US20060014705A1 (en) * | 2004-06-30 | 2006-01-19 | Howitz Konrad T | Compositions and methods for selectively activating human sirtuins |
| US20060024385A1 (en) * | 2004-07-27 | 2006-02-02 | Pedersen Mark A | Metabolic capacity enhancing compositions and methods for use in a mammal |
| PL369552A1 (pl) * | 2004-08-12 | 2006-02-20 | Sgp & Sons Ab | Preparat farmaceutyczny lub/i żywieniowy lub/i laboratoryjny wzmagający, wspomagający funkcjonowanie komórek nerwowych i układu nerwowego oraz zastosowanie preparatu farmaceutycznego lub/i żywieniowego w procesie ochrony funkcji układu nerwowego oraz zastosowanie preparatu do ochrony wzrostu stymulacji namnażania i zapobiegania apoptozie komórek nerwowych |
| CA2595159A1 (en) * | 2005-01-13 | 2006-07-20 | Sirtris Pharmaceuticals, Inc. | Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders |
| WO2006114193A1 (en) * | 2005-04-28 | 2006-11-02 | Unilever N.V. | Peptides having an ace inhibiting effect |
| WO2006138418A2 (en) * | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| US20070004639A1 (en) * | 2005-07-01 | 2007-01-04 | Bodybio, Inc. | Methods and compositions for treating Parkinson's disease |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| US20080118529A1 (en) * | 2005-07-13 | 2008-05-22 | Gebbink Martijn Frans Ben Gera | Adjuvation Through Cross -Beta Structure |
| US20070015133A1 (en) * | 2005-07-13 | 2007-01-18 | Umc Utrecht Holding B.V. | Method for detecting and/or removing protein and/or peptide comprising a cross-beta structure from an aqueous solution comprising a protein |
| WO2007008072A2 (en) * | 2005-07-13 | 2007-01-18 | Crossbeta Biosciences B.V. | CROSS-ß STRUCTURE BINDING COMPOUNDS |
| US8114832B2 (en) * | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
| DE102005035917A1 (de) * | 2005-07-28 | 2007-02-01 | November Ag | Verwendung von Isocitrat, Isocitronensäure oder einem Derivat davon zur Herstellung eines Medikaments |
| DK1909600T3 (da) * | 2005-07-29 | 2012-07-30 | Tima Foundation | Sammensætning til moderering af alkoholmetabolisme og til at reducere risikoen for alkoholforårsagede sygdomme |
| AU2007249847A1 (en) * | 2006-05-11 | 2007-11-22 | Avicena Group, Inc. | Methods of treating a neurological disorder with creatine monohydrate |
| US8435547B2 (en) * | 2006-08-30 | 2013-05-07 | John P. Blass | Cream for stimulating mitochondrial activity in the skin |
| EP2680009A1 (en) | 2007-02-08 | 2014-01-01 | Biogen Idec MA Inc. | Nrf2 screening assays and related methods and compositions |
| EP3135282A1 (en) * | 2007-02-08 | 2017-03-01 | Biogen MA Inc. | Neuroprotection in demyelinating diseases |
| EP2058001A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Enhancement of immunogenicity of antigens |
| EP2058000A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Immunogenic compositions capable of activating T cells |
| US20090269796A1 (en) * | 2007-12-05 | 2009-10-29 | The General Hospital Corporation | Methods of detecting and treating myocardial ischemia and myocardial infarction |
| WO2010033045A1 (en) * | 2008-09-16 | 2010-03-25 | Igor Anatolievich Pomytkin | Compositions and methods for prevention or treatment of beta amyloid deposition |
| US9233099B2 (en) | 2012-01-11 | 2016-01-12 | University Of Cincinnati | Methods of treating cognitive dysfunction by modulating brain energy metabolism |
| PL2897604T3 (pl) | 2012-09-19 | 2018-10-31 | Grespo Ab | Kompozycje do ulepszenia funkcji mózgu |
| US20140243400A1 (en) * | 2013-02-28 | 2014-08-28 | University of Alaska Anchorage | Compositions comprising citric acid and malic acid and methods and uses thereof |
| WO2014160423A1 (en) | 2013-03-13 | 2014-10-02 | Genetic Disease Investigators, LLC | Methods and compositions for correction of organ dysfunction |
| US10238673B2 (en) | 2013-03-13 | 2019-03-26 | Genetic Disease Investigators, LLC | Methods and compositions for treatment of dry eye and correction of organ dysfunctions |
| KR102542842B1 (ko) * | 2016-09-22 | 2023-06-14 | 알란 비. 캐쉬 | Pms의 증상을 완화하는 방법 |
| JP6129395B1 (ja) * | 2016-10-29 | 2017-05-17 | 誠一 荒木 | ミトコンドリア活性化に起因した血管内皮細胞保護回復用還元型ビタミンb2製剤 |
| IT201800006725A1 (it) * | 2018-06-27 | 2019-12-27 | Composizioni comprendenti aminoacidi per l'uso nella prevenzione e nel trattamento di malattie epatiche | |
| CN112888436A (zh) * | 2018-10-11 | 2021-06-01 | 安布里亚制药公司 | Tca循环中间体和其使用方法 |
| IT202000000442A1 (it) | 2020-01-13 | 2021-07-13 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per l'uso nella prevenzione e nel trattamento di effetti collaterali della chemioterapia |
| WO2022166847A1 (zh) * | 2021-02-05 | 2022-08-11 | 崔德斌 | 一种组合物及其用途 |
| CN115212195B (zh) * | 2022-06-17 | 2024-02-27 | 重庆医科大学 | 苹果酸在制备预防和/或治疗抑郁症的药物中的用途 |
| US20250221952A1 (en) * | 2025-03-14 | 2025-07-10 | Louis Dischler | Methods and compositions for large modifications of atp output by inner mitochondrial membrane latching |
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| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
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| US5589182A (en) * | 1993-12-06 | 1996-12-31 | Tashiro; Renki | Compositions and method of treating cardio-, cerebro-vascular and alzheimer's diseases and depression |
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| WO2003068215A1 (fr) * | 2002-02-14 | 2003-08-21 | Ajinomoto Co., Inc. | Médicaments pour maladies mitochondriales |
| JP2011225609A (ja) * | 2003-07-01 | 2011-11-10 | Essentys Ab | 栄養失調及び高血漿グルコース状態を治療するためのアルファ−ケトグルタル酸の使用 |
| JP2007529408A (ja) * | 2003-07-01 | 2007-10-25 | エッセンティス アクティエボラーグ | 栄養失調及び高血漿グルコース状態を治療するためのアルファ−ケトグルタル酸の使用 |
| JPWO2006025247A1 (ja) * | 2004-08-30 | 2008-05-08 | 株式会社カネカ | ミトコンドリア賦活剤 |
| JP2015145417A (ja) * | 2004-12-17 | 2015-08-13 | アラン ビー. キャッシュ | 寿命を拡大させ、かつ加齢関連疾患の発症を遅らせるための方法 |
| JP2013100323A (ja) * | 2004-12-17 | 2013-05-23 | Alan B Cash | 寿命を拡大させ、かつ加齢関連疾患の発症を遅らせるための方法 |
| JP2017019864A (ja) * | 2004-12-17 | 2017-01-26 | アラン ビー. キャッシュ | 寿命を拡大させ、かつ加齢関連疾患の発症を遅らせるための方法 |
| JP2008524256A (ja) * | 2004-12-17 | 2008-07-10 | アラン ビー. キャッシュ | 寿命を拡大させ、かつ加齢関連疾患の発症を遅らせるための方法 |
| JP2012107023A (ja) * | 2004-12-21 | 2012-06-07 | Critical Care Connections Inc | 治療用栄養組成物又は組合せ、及びそれらの使用方法 |
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| JP2018030795A (ja) * | 2016-08-23 | 2018-03-01 | 株式会社Hbcフナト | 脳機能改善組成物 |
| JP2020528400A (ja) * | 2017-07-28 | 2020-09-24 | プロフェッショナル ダイエテティクス インターナショナル エス.アール.エル. | ミトコンドリア機能障害関連疾患の治療に使用するための、アミノ酸を備える組成物 |
| JP7266767B2 (ja) | 2017-07-28 | 2023-05-01 | プロフェッショナル ダイエテティクス エス.ピー.エー. | ミトコンドリア機能障害関連疾患の治療に使用するための、アミノ酸を備える組成物 |
| JP2023071939A (ja) * | 2017-07-28 | 2023-05-23 | プロフェッショナル ダイエテティクス エス.ピー.エー. | ミトコンドリア機能障害関連疾患の治療に使用するための、アミノ酸を備える組成物 |
| JP7513311B2 (ja) | 2017-07-28 | 2024-07-09 | プロフェッショナル ダイエテティクス エス.ピー.エー. | ミトコンドリア機能障害関連疾患の治療に使用するための、アミノ酸を備える組成物 |
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Also Published As
| Publication number | Publication date |
|---|---|
| AU760140B2 (en) | 2003-05-08 |
| EP1032403A4 (en) | 2004-03-31 |
| ATE555780T1 (de) | 2012-05-15 |
| AU9213998A (en) | 1999-05-17 |
| CA2306875C (en) | 2011-01-04 |
| CA2306875A1 (en) | 1999-05-06 |
| JP2010189432A (ja) | 2010-09-02 |
| US6537969B1 (en) | 2003-03-25 |
| WO1999021565A1 (en) | 1999-05-06 |
| US20030176365A1 (en) | 2003-09-18 |
| EP1032403A1 (en) | 2000-09-06 |
| EP1032403B1 (en) | 2012-05-02 |
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