JP2000514307A - 増加した標的特異的t▲下m▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法 - Google Patents

増加した標的特異的t▲下m▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法

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Publication number
JP2000514307A
JP2000514307A JP10506265A JP50626598A JP2000514307A JP 2000514307 A JP2000514307 A JP 2000514307A JP 10506265 A JP10506265 A JP 10506265A JP 50626598 A JP50626598 A JP 50626598A JP 2000514307 A JP2000514307 A JP 2000514307A
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nucleic acid
probe
nucleotide
analyte
region
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Ceased
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Japanese (ja)
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JP2000514307A5 (ref
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ベッカー,マイケル・マクレラン
マジュレッシ,メールダッド
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ジェン―プローブ・インコーポレーテッド
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Publication of JP2000514307A5 publication Critical patent/JP2000514307A5/ja
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6832Enhancement of hybridisation reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6865Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP10506265A 1996-07-16 1997-07-15 増加した標的特異的t▲下m▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法 Ceased JP2000514307A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2181896P 1996-07-16 1996-07-16
US60/021,818 1996-07-16
PCT/US1997/012347 WO1998002582A2 (en) 1996-07-16 1997-07-15 Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific t¿m?

Related Child Applications (1)

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JP2008137832A Division JP4527789B2 (ja) 1996-07-16 2008-05-27 増加した標的特異的tmを持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法

Publications (2)

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JP2000514307A true JP2000514307A (ja) 2000-10-31
JP2000514307A5 JP2000514307A5 (ref) 2007-08-02

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JP10506265A Ceased JP2000514307A (ja) 1996-07-16 1997-07-15 増加した標的特異的t▲下m▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法
JP2008137832A Expired - Lifetime JP4527789B2 (ja) 1996-07-16 2008-05-27 増加した標的特異的tmを持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法

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JP2008137832A Expired - Lifetime JP4527789B2 (ja) 1996-07-16 2008-05-27 増加した標的特異的tmを持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法

Country Status (11)

Country Link
US (3) US6130038A (ref)
EP (1) EP0912767B1 (ref)
JP (2) JP2000514307A (ref)
KR (1) KR20000023814A (ref)
AT (1) ATE339514T1 (ref)
AU (1) AU726821B2 (ref)
CA (1) CA2260749A1 (ref)
DE (1) DE69736667T2 (ref)
DK (1) DK0912767T3 (ref)
ES (1) ES2270467T3 (ref)
WO (1) WO1998002582A2 (ref)

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EP0912767B1 (en) 2006-09-13
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CA2260749A1 (en) 1998-01-22
JP4527789B2 (ja) 2010-08-18
US6903206B1 (en) 2005-06-07
WO1998002582A2 (en) 1998-01-22
KR20000023814A (ko) 2000-04-25
ATE339514T1 (de) 2006-10-15
ES2270467T3 (es) 2007-04-01
US6130038A (en) 2000-10-10
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