|
US6346614B1
(en)
*
|
1992-07-23 |
2002-02-12 |
Hybridon, Inc. |
Hybrid oligonucleotide phosphorothioates
|
|
NZ513757A
(en)
|
1999-02-26 |
2004-12-24 |
Univ British Columbia |
Antisense oligonucleotides to inhibit TRPM-2 expression and delay androgen independance in prostatic tumour cells
|
|
US7569551B2
(en)
|
2000-02-25 |
2009-08-04 |
The University Of British Columbia |
Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides
|
|
KR20080023768A
(ko)
|
2000-03-30 |
2008-03-14 |
화이트헤드 인스티튜트 포 바이오메디칼 리서치 |
Rna 간섭의 rna 서열 특이적인 매개체
|
|
EP1191097A1
(en)
|
2000-09-21 |
2002-03-27 |
Leids Universitair Medisch Centrum |
Induction of exon skipping in eukaryotic cells
|
|
CZ302719B6
(cs)
|
2000-12-01 |
2011-09-21 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Izolovaná molekula dvouretezcové RNA, zpusob její výroby a její použití
|
|
DK1465995T3
(da)
*
|
2002-01-17 |
2008-10-20 |
Univ British Columbia |
Bispespecifikke antisense-olignukleotider der inhiberer IGFBP-2 og IGFBP og fremgangsmåder til anvendelse deraf
|
|
AU2003225410A1
(en)
|
2003-03-21 |
2004-10-11 |
Academisch Ziekenhuis Leiden |
Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
|
|
EP1667731B1
(en)
*
|
2003-10-01 |
2013-05-22 |
The University Of British Columbia |
Bispecific oligonucleotide for the treatment of cns malignancies
|
|
KR101147147B1
(ko)
|
2004-04-01 |
2012-05-25 |
머크 샤프 앤드 돔 코포레이션 |
Rna 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드
|
|
US8710020B2
(en)
*
|
2004-04-02 |
2014-04-29 |
The University Of British Columbia |
Clusterin antisense therapy for treatment of cancer
|
|
HRP20110352T1
(hr)
|
2004-06-28 |
2011-06-30 |
The University Of Western Australia |
Antisens olinukleotidi za induciranje zaobilaženja egzona i postupci njihove upotrebe
|
|
USRE48960E1
(en)
|
2004-06-28 |
2022-03-08 |
The University Of Western Australia |
Antisense oligonucleotides for inducing exon skipping and methods of use thereof
|
|
US7923207B2
(en)
|
2004-11-22 |
2011-04-12 |
Dharmacon, Inc. |
Apparatus and system having dry gene silencing pools
|
|
US7935811B2
(en)
|
2004-11-22 |
2011-05-03 |
Dharmacon, Inc. |
Apparatus and system having dry gene silencing compositions
|
|
US20060166234A1
(en)
|
2004-11-22 |
2006-07-27 |
Barbara Robertson |
Apparatus and system having dry control gene silencing compositions
|
|
PT1814595E
(pt)
*
|
2004-11-23 |
2014-04-02 |
Univ British Columbia |
Tratamento de cancro com uma combinação de um agente que perturba a via de sinalização egf e um oligonucleótido que reduz os níveis de clusterina
|
|
US8288354B2
(en)
|
2005-12-28 |
2012-10-16 |
The Scripps Research Institute |
Natural antisense and non-coding RNA transcripts as drug targets
|
|
WO2007123391A1
(en)
|
2006-04-20 |
2007-11-01 |
Academisch Ziekenhuis Leiden |
Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene.
|
|
EP1857548A1
(en)
|
2006-05-19 |
2007-11-21 |
Academisch Ziekenhuis Leiden |
Means and method for inducing exon-skipping
|
|
US20070275029A1
(en)
*
|
2006-05-26 |
2007-11-29 |
Ico Therapeutics Inc. |
Therapeutic drug combinations and delivery systems comprising c-raf kinase antisense polynucleotides for treating ocular diseases and disorders
|
|
PL2049664T3
(pl)
|
2006-08-11 |
2012-02-29 |
Biomarin Tech Bv |
Jednoniciowe oligonukleotydy komplementarne do powtarzalnych elementów do leczenia chorób genetycznych związanych z niestabilnością powtórzeń DNA
|
|
US8252755B2
(en)
|
2006-09-22 |
2012-08-28 |
Dharmacon, Inc. |
Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
|
|
CN103212085A
(zh)
|
2007-07-12 |
2013-07-24 |
普罗森那技术公司 |
用于使化合物靶向多种选定器官或组织的分子
|
|
USRE48468E1
(en)
|
2007-10-26 |
2021-03-16 |
Biomarin Technologies B.V. |
Means and methods for counteracting muscle disorders
|
|
CA2704049A1
(en)
|
2007-10-26 |
2009-04-30 |
Academisch Ziekenhuis Leiden |
Means and methods for counteracting muscle disorders
|
|
CN101980726A
(zh)
|
2008-02-08 |
2011-02-23 |
普罗森那控股公司 |
治疗与dna重复不稳定性相关的遗传病症的方法和装置
|
|
US8188060B2
(en)
|
2008-02-11 |
2012-05-29 |
Dharmacon, Inc. |
Duplex oligonucleotides with enhanced functionality in gene regulation
|
|
EP2119783A1
(en)
|
2008-05-14 |
2009-11-18 |
Prosensa Technologies B.V. |
Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means
|
|
RU2604489C2
(ru)
|
2008-10-03 |
2016-12-10 |
КьюРНА,Инк.,US |
Лечение заболеваний, связанных с аполипопротеином-а1, путем ингибирования природного антисмыслового транскрипта аполипопротеина-а1
|
|
WO2010048549A2
(en)
*
|
2008-10-24 |
2010-04-29 |
Isis Pharmaceuticals, Inc. |
5' and 2' bis-substituted nucleosides and oligomeric compounds prepared therefrom
|
|
WO2010048586A1
(en)
|
2008-10-24 |
2010-04-29 |
Avi Biopharma, Inc. |
Multiple exon skipping compositions for dmd
|
|
US8927511B2
(en)
|
2008-12-04 |
2015-01-06 |
Curna, Inc. |
Treatment of vascular endothelial growth factor (VEGF) related diseases by inhibition of natural antisense transcript to VEGF
|
|
KR101840618B1
(ko)
|
2008-12-04 |
2018-03-20 |
큐알엔에이, 인크. |
종양 억제 유전자에 대한 천연 안티센스 전사체의 억제에 의해 종양 억제 유전자 관련된 질환의 치료
|
|
WO2010065792A2
(en)
|
2008-12-04 |
2010-06-10 |
Curna, Inc. |
Treatment of erythropoietin (epo) related diseases by inhibition of natural antisense transcript to epo
|
|
EP2396038B1
(en)
|
2009-02-12 |
2015-10-21 |
CuRNA, Inc. |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
|
MX2011009751A
(es)
|
2009-03-16 |
2011-09-29 |
Opko Curna Llc |
Tratamiento de enfermedades relacionadas con factor nuclear (eritroide derivado 2) tipo 2 (nrf2) por inhibicion del transcrito antisentido natural a nrf2.
|
|
WO2010107740A2
(en)
|
2009-03-17 |
2010-09-23 |
Curna, Inc. |
Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
|
|
EP2421971B1
(en)
|
2009-04-24 |
2016-07-06 |
BioMarin Technologies B.V. |
Oligonucleotide comprising an inosine for treating dmd
|
|
EP2427553A4
(en)
|
2009-05-06 |
2012-11-07 |
Opko Curna Llc |
TREATMENT OF LIPID TRANSPORT AND METABOLISM-RELATED DISEASES BY INHIBITING THE NATURAL ANTISENSE TRANSCRIPT AGAINST A LIPID TRANSPORT AND METABOLIC TREATMENT
|
|
CN102803492B
(zh)
|
2009-05-06 |
2016-06-29 |
库尔纳公司 |
通过抑制针对三重四脯氨酸(ttp)的天然反义转录物来治疗ttp相关疾病
|
|
WO2010129861A2
(en)
|
2009-05-08 |
2010-11-11 |
Curna, Inc. |
Treatment of dystrophin family related diseases by inhibition of natural antisense transcript to dmd family
|
|
WO2010135329A2
(en)
|
2009-05-18 |
2010-11-25 |
Curna, Inc. |
Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor
|
|
WO2010135695A2
(en)
|
2009-05-22 |
2010-11-25 |
Curna, Inc. |
TREATMENT OF TRANSCRIPTION FACTOR E3 (TFE3) and INSULIN RECEPTOR SUBSTRATE 2 (IRS2) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO TFE3
|
|
CN103221541B
(zh)
|
2009-05-28 |
2017-03-01 |
库尔纳公司 |
通过抑制抗病毒基因的天然反义转录物来治疗抗病毒基因相关疾病
|
|
ES2620960T3
(es)
|
2009-06-16 |
2017-06-30 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con un gen de colágeno mediante la inhibición de un transcrito antisentido natural a un gen de colágeno
|
|
CN102612560B
(zh)
|
2009-06-16 |
2017-10-17 |
库尔纳公司 |
通过抑制针对对氧磷酶1(pon1)的天然反义转录物来治疗pon1相关的疾病
|
|
CN102597238B
(zh)
|
2009-06-24 |
2016-06-29 |
库尔纳公司 |
通过抑制针对肿瘤坏死因子受体2(tnfr2)的天然反义转录物来治疗tnfr2相关的疾病
|
|
CN102482672B
(zh)
|
2009-06-26 |
2016-11-09 |
库尔纳公司 |
通过抑制唐氏综合征基因的天然反义转录物治疗唐氏综合征基因相关疾病
|
|
WO2011005779A2
(en)
|
2009-07-07 |
2011-01-13 |
University Of Southern California |
Biomarkers for the early detection of autoimmune diseases
|
|
JP2013500017A
(ja)
|
2009-07-24 |
2013-01-07 |
カッパーアールエヌエー,インコーポレイテッド |
サ−チュイン(sirt)への天然アンチセンス転写物の阻止によるサ−チュイン(sirt)関連疾患の治療
|
|
EP2462229B1
(en)
|
2009-08-05 |
2016-05-11 |
CuRNA, Inc. |
Treatment of insulin gene (ins) related diseases by inhibition of natural antisense transcript to an insulin gene (ins)
|
|
CN102625841A
(zh)
|
2009-08-11 |
2012-08-01 |
欧科库尔纳有限责任公司 |
通过抑制脂连蛋白(adipoq)的天然反义转录物治疗脂连蛋白(adipoq)相关疾病
|
|
WO2011022606A2
(en)
|
2009-08-21 |
2011-02-24 |
Curna, Inc. |
Treatment of 'c terminus of hsp70-interacting protein' (chip) related diseases by inhibition of natural antisense transcript to chip
|
|
KR101892760B1
(ko)
|
2009-08-25 |
2018-08-28 |
큐알엔에이, 인크. |
IQGAP에 대한 천연 안티센스 전사체의 억제에 의한 GTPase 활성화 단백질을 함유하는 IQ 모티프(IQGAP)와 관련된 질환의 치료
|
|
NO2480669T3
(enExample)
|
2009-09-25 |
2018-04-07 |
|
|
|
KR102113306B1
(ko)
|
2009-11-12 |
2020-05-21 |
더 유니버시티 오브 웨스턴 오스트레일리아 |
안티센스 분자 및 이를 이용한 질환 치료방법
|
|
WO2011084455A2
(en)
|
2009-12-16 |
2011-07-14 |
Opko Curna, Llc. |
Treatment of membrane bound transcription factor peptidase, site 1 (mbtps1) related diseases by inhibition of natural antisense transcript to mbtps1
|
|
WO2011079263A2
(en)
|
2009-12-23 |
2011-06-30 |
Curna, Inc. |
Treatment of uncoupling protein 2 (ucp2) related diseases by inhibition of natural antisense transcript to ucp2
|
|
KR101891352B1
(ko)
|
2009-12-23 |
2018-08-24 |
큐알엔에이, 인크. |
간세포 성장 인자(hgf)에 대한 천연 안티센스 전사체의 억제에 의한 hgf 관련 질환의 치료
|
|
CN102782134B
(zh)
|
2009-12-29 |
2017-11-24 |
库尔纳公司 |
通过抑制核呼吸因子1(nrf1)的天然反义转录物而治疗nrf1相关疾病
|
|
CN102770540B
(zh)
|
2009-12-29 |
2017-06-23 |
库尔纳公司 |
通过抑制肿瘤蛋白63(p63)的天然反义转录物而治疗p63相关疾病
|
|
CN102791862B
(zh)
|
2009-12-31 |
2017-04-05 |
库尔纳公司 |
通过抑制胰岛素受体底物2(irs2)和转录因子e3(tfe3)的天然反义转录物而治疗irs2相关疾病
|
|
CN102906264B
(zh)
|
2010-01-04 |
2017-08-04 |
库尔纳公司 |
通过抑制干扰素调节因子8(irf8)的天然反义转录物而治疗irf8相关疾病
|
|
US8912157B2
(en)
|
2010-01-06 |
2014-12-16 |
Curna, Inc. |
Treatment of pancreatic developmental gene related diseases by inhibition of natural antisense transcript to a pancreatic developmental gene
|
|
CA2786535C
(en)
|
2010-01-11 |
2019-03-26 |
Curna, Inc. |
Treatment of sex hormone binding globulin (shbg) related diseases by inhibition of natural antisense transcript to shbg
|
|
JP5981850B2
(ja)
|
2010-01-25 |
2016-08-31 |
カッパーアールエヌエー,インコーポレイテッド |
RNaseH1に対する天然アンチセンス転写物の阻害によるRNaseH1関連疾患の治療
|
|
JP5976548B2
(ja)
|
2010-02-22 |
2016-08-23 |
カッパーアールエヌエー,インコーポレイテッド |
Pycr1に対する天然アンチセンス転写物の阻害によるピロリン−5−カルボン酸レダクターゼ1(pycr1)関連疾患の治療
|
|
JP6017964B2
(ja)
|
2010-03-01 |
2016-11-02 |
ティーエーユー・セラピューティクス・エルエルシー |
癌診断および撮像
|
|
WO2011112516A1
(en)
*
|
2010-03-08 |
2011-09-15 |
Ico Therapeutics Inc. |
Treating and preventing hepatitis c virus infection using c-raf kinase antisense oligonucleotides
|
|
CN102869777B
(zh)
|
2010-04-02 |
2018-11-02 |
库尔纳公司 |
通过抑制集落刺激因子3(csf3)的天然反义转录物而治疗csf3相关疾病
|
|
WO2011127337A2
(en)
|
2010-04-09 |
2011-10-13 |
Opko Curna Llc |
Treatment of fibroblast growth factor 21 (fgf21) related diseases by inhibition of natural antisense transcript to fgf21
|
|
CN107988228B
(zh)
|
2010-05-03 |
2022-01-25 |
库尔纳公司 |
通过抑制沉默调节蛋白(sirt)的天然反义转录物而治疗沉默调节蛋白(sirt)相关疾病
|
|
TWI531370B
(zh)
|
2010-05-14 |
2016-05-01 |
可娜公司 |
藉由抑制par4天然反股轉錄本治療par4相關疾病
|
|
EP3299464B1
(en)
|
2010-05-26 |
2019-10-02 |
CuRNA, Inc. |
Treatment of atonal homolog 1 (atoh1) related diseases by inhibition of natural antisense transcript to atoh1
|
|
RU2620978C2
(ru)
|
2010-05-26 |
2017-05-30 |
Курна, Инк. |
Лечение заболеваний, связанных с метионинсульфоксидредуктазой а (msra), путем ингибирования природного антисмыслового транскрипта гена msra
|
|
ES2863526T3
(es)
|
2010-06-23 |
2021-10-11 |
Curna Inc |
Tratamiento de enfermedades relacionadas con la subunidad alfa del canal de sodio (SCNA), controlado por voltaje, mediante inhibición de la transcripción antisentido natural a SCNA
|
|
WO2012009402A2
(en)
|
2010-07-14 |
2012-01-19 |
Opko Curna Llc |
Treatment of discs large homolog (dlg) related diseases by inhibition of natural antisense transcript to dlg
|
|
ES2640755T3
(es)
|
2010-10-06 |
2017-11-06 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con la Sialidasa 4 (neu4) mediante inhibición del transcrito antisentido natural al gen neu4
|
|
RU2597972C2
(ru)
|
2010-10-22 |
2016-09-20 |
Курна Инк. |
Лечение заболеваний, связанных с геном альфа-l-идуронидазы (idua), путем ингибирования природного антисмыслового транскрипта гена idua
|
|
US9920317B2
(en)
|
2010-11-12 |
2018-03-20 |
The General Hospital Corporation |
Polycomb-associated non-coding RNAs
|
|
DK2638163T3
(en)
|
2010-11-12 |
2017-07-24 |
Massachusetts Gen Hospital |
POLYCOMB-ASSOCIATED NON-CODING RNAs
|
|
WO2012068340A2
(en)
|
2010-11-18 |
2012-05-24 |
Opko Curna Llc |
Antagonat compositions and methods of use
|
|
EP2643463B1
(en)
|
2010-11-23 |
2017-09-27 |
CuRNA, Inc. |
Treatment of nanog related diseases by inhibition of natural antisense transcript to nanog
|
|
TWI678375B
(zh)
|
2011-06-09 |
2019-12-01 |
可娜公司 |
藉由抑制共濟蛋白(frataxin,fxn)之天然反股轉錄本治療fxn相關疾病
|
|
CN108272782B
(zh)
|
2011-09-06 |
2021-04-23 |
库尔纳公司 |
小分子在制备治疗Dravet综合征或全面性癫痫伴热性惊厥附加症的药物中的用途
|
|
SG10201601917XA
(en)
|
2011-09-12 |
2016-04-28 |
Tau Therapeutics Llc |
Antagonists of products of the hs.459642 unigene cluster for the inhibition of proliferation, development or differentiation of stem cells including cancer stem cells
|
|
US9580708B2
(en)
|
2011-09-14 |
2017-02-28 |
Rana Therapeutics, Inc. |
Multimeric oligonucleotides compounds
|
|
NZ627896A
(en)
|
2012-01-27 |
2016-11-25 |
Biomarin Technologies B V |
Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy
|
|
RU2661104C2
(ru)
|
2012-03-15 |
2018-07-11 |
КЁРНА, Инк. |
Лечение заболеваний, связанных с нейтрофическим фактором головного мозга (bdnf), путем ингибирования природного антисмыслового транскрипта bdnf
|
|
US10837014B2
(en)
|
2012-05-16 |
2020-11-17 |
Translate Bio Ma, Inc. |
Compositions and methods for modulating SMN gene family expression
|
|
US10059941B2
(en)
|
2012-05-16 |
2018-08-28 |
Translate Bio Ma, Inc. |
Compositions and methods for modulating SMN gene family expression
|
|
CN104583399A
(zh)
|
2012-05-16 |
2015-04-29 |
Rana医疗有限公司 |
用于调节血红蛋白基因家族表达的组合物和方法
|
|
AU2013262709A1
(en)
|
2012-05-16 |
2015-01-22 |
Rana Therapeutics, Inc. |
Compositions and methods for modulating MECP2 expression
|
|
SG11201407486PA
(en)
|
2012-05-16 |
2014-12-30 |
Rana Therapeutics Inc |
Compositions and methods for modulating utrn expression
|
|
US10174323B2
(en)
|
2012-05-16 |
2019-01-08 |
The General Hospital Corporation |
Compositions and methods for modulating ATP2A2 expression
|
|
AU2013315225B2
(en)
|
2012-09-14 |
2018-11-08 |
Translate Bio Ma, Inc. |
Multimeric oligonucleotide compounds
|
|
WO2014100602A1
(en)
|
2012-12-20 |
2014-06-26 |
Hospital For Special Surgery |
Treatment of egf-receptor dependent pathologies
|
|
NZ731587A
(en)
|
2013-03-14 |
2021-07-30 |
Sarepta Therapeutics Inc |
Exon skipping compositions for treating muscular dystrophy
|
|
CN113633787A
(zh)
|
2013-03-15 |
2021-11-12 |
萨勒普塔医疗公司 |
改进的用于治疗肌营养不良的组合物
|
|
JP2016531570A
(ja)
|
2013-08-16 |
2016-10-13 |
ラナ セラピューティクス インコーポレイテッド |
ユークロマチン領域を標的とするオリゴヌクレオチド
|
|
PT3049085T
(pt)
|
2013-09-26 |
2021-10-01 |
Beth Israel Deaconess Medical Ct Inc |
Inibidores de sgk1 no tratamento da síndrome do qt longo
|
|
CA2941401C
(en)
|
2014-03-20 |
2019-06-11 |
Cymabay Therapeutics, Inc. |
Treatment of intrahepatic cholestatic diseases
|
|
US10272058B2
(en)
|
2014-03-20 |
2019-04-30 |
Cymabay Therapeutics, Inc. |
Treatment of intrahepatic cholestatic diseases
|
|
KR102374499B1
(ko)
|
2014-04-11 |
2022-03-14 |
사이머베이 쎄라퓨틱스, 인코퍼레이티드 |
Nafld 및 nash 의 치료
|
|
GB201410693D0
(en)
|
2014-06-16 |
2014-07-30 |
Univ Southampton |
Splicing modulation
|
|
SG11201702682PA
(en)
|
2014-10-03 |
2017-04-27 |
Cold Spring Harbor Lab |
Targeted augmentation of nuclear gene output
|
|
CA2966044A1
(en)
|
2014-10-30 |
2016-05-06 |
The General Hospital Corporation |
Methods for modulating atrx-dependent gene repression
|
|
US10758558B2
(en)
|
2015-02-13 |
2020-09-01 |
Translate Bio Ma, Inc. |
Hybrid oligonucleotides and uses thereof
|
|
US10900036B2
(en)
|
2015-03-17 |
2021-01-26 |
The General Hospital Corporation |
RNA interactome of polycomb repressive complex 1 (PRC1)
|
|
SG11201802870RA
(en)
|
2015-10-09 |
2018-05-30 |
Univ Southampton |
Modulation of gene expression and screening for deregulated protein expression
|
|
ES2936400T3
(es)
|
2015-10-22 |
2023-03-16 |
Cavion Inc |
Métodos para tratar el síndrome Angelman
|
|
US11096956B2
(en)
|
2015-12-14 |
2021-08-24 |
Stoke Therapeutics, Inc. |
Antisense oligomers and uses thereof
|
|
EP3933041B1
(en)
|
2015-12-14 |
2024-01-31 |
Cold Spring Harbor Laboratory |
Antisense oligomers for treatment of autosomal dominant retardation
|
|
JOP20200228A1
(ar)
|
2015-12-21 |
2017-06-16 |
Novartis Ag |
تركيبات وطرق لخفض تعبير البروتين tau
|
|
WO2018152317A1
(en)
|
2017-02-15 |
2018-08-23 |
Cavion, Inc. |
Calcium channel inhibitors
|
|
SG10202111885PA
(en)
|
2017-04-26 |
2021-12-30 |
Cavion Inc |
Methods for improving memory and cognition and for treating memory and cognitive disorders
|
|
CN107460219B
(zh)
*
|
2017-07-24 |
2020-04-10 |
武汉大学 |
一种差异核酸酶切方法及其在LC-MS法检测mRNA内部修饰中的应用
|
|
EP3673080B1
(en)
|
2017-08-25 |
2023-10-18 |
Stoke Therapeutics, Inc. |
Antisense oligomers for treatment of conditions and diseases
|
|
US12060558B2
(en)
|
2018-05-04 |
2024-08-13 |
Stoke Therapeutics, Inc. |
Methods and compositions for treatment of cholesteryl ester storage disease
|
|
TWI879741B
(zh)
|
2018-10-03 |
2025-04-11 |
美商卡凡恩公司 |
以(r)-2-(4-異丙基苯基)-n-(1-(5-(2,2,2-三氟乙氧基)吡啶-2-基)乙基)乙醯胺治療自發性震顫
|
|
EP4150092A4
(en)
|
2020-05-11 |
2024-11-06 |
Stoke Therapeutics, Inc. |
OPA1 ANTISENSE OLIGOMERS FOR THE TREATMENT OF DISEASES AND CONDITIONS
|