ITRM20020016A0 - Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza - Google Patents
Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizzaInfo
- Publication number
- ITRM20020016A0 ITRM20020016A0 IT2002RM000016A ITRM20020016A ITRM20020016A0 IT RM20020016 A0 ITRM20020016 A0 IT RM20020016A0 IT 2002RM000016 A IT2002RM000016 A IT 2002RM000016A IT RM20020016 A ITRM20020016 A IT RM20020016A IT RM20020016 A0 ITRM20020016 A0 IT RM20020016A0
- Authority
- IT
- Italy
- Prior art keywords
- derivatives
- phenylalkyleterocyclic
- diionic
- medicines
- phenyl
- Prior art date
Links
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000002218 hypoglycaemic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/76—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and etherified hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/48—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/58—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002RM000016A ITRM20020016A1 (it) | 2002-01-15 | 2002-01-15 | Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza |
JP2003559969A JP2005514452A (ja) | 2002-01-15 | 2003-01-13 | フェニル(アルキル)カルボン酸誘導体およびジオニックフェニルアルキル複素環誘導体およびそれらの血清グルコースおよび/または血清脂質低下活性を有する医薬としての使用 |
BR0306880-3A BR0306880A (pt) | 2002-01-15 | 2003-01-13 | Derivados do ácido fenil(alquil)carboxìlico e derivados diÈnicos de fenilalquila heterocìclica e o uso dos mesmos como medicamentos com atividade de redução de glicose do soro e/ou de lipìdios no soro |
EP03729544A EP1465858A2 (en) | 2002-01-15 | 2003-01-13 | Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity |
CNB038022958A CN100509783C (zh) | 2002-01-15 | 2003-01-13 | 苯基(烷基)羧酸衍生物和二酸苯基烷基杂环衍生物及其用作具有血清葡萄糖和/或血清脂降低活性的药物的应用 |
AU2003209676A AU2003209676B2 (en) | 2002-01-15 | 2003-01-13 | Phenyl(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity |
PCT/IT2003/000007 WO2003059864A2 (en) | 2002-01-15 | 2003-01-13 | Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity |
CA002472209A CA2472209A1 (en) | 2002-01-15 | 2003-01-13 | Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity |
US10/501,135 US20050032787A1 (en) | 2002-01-15 | 2003-01-13 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity |
MXPA04006802A MXPA04006802A (es) | 2002-01-15 | 2003-01-13 | Derivados de acido fenil(alquil)carboxilico y derivados fenilalquilheterociclicos dionicos y su uso como medicinas con actividad reductora de glucosa en suero y/o de lipidos en suero.. |
KR1020047010463A KR100969979B1 (ko) | 2002-01-15 | 2003-01-13 | 페닐(알킬)카르복시산 유도체 및 디이온성페닐알킬헤테로사이클릭 유도체, 및 혈청 글루코스및/또는 혈청 지질 강하 활성을 갖는 약제로서의 그의 용도 |
PL03372616A PL372616A1 (en) | 2002-01-15 | 2003-01-13 | Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity |
TW092100694A TW200302737A (en) | 2002-01-15 | 2003-01-14 | Phenyl(alkyl) carboxylic acid derivatives and dionic phenylalkylheterocyclic dervivatives and their use as medicines with serum glucose and/or serum lipid lowering activity |
ARP030100104A AR038147A1 (es) | 2002-01-15 | 2003-01-15 | Compuestos derivados del acido fenil(alquil)carboxilico y compuestos derivados fenilalquilheterociclicos dionicos, su empleo y composiciones farmaceuticas que los contienen |
HK05108580.4A HK1076628A1 (en) | 2002-01-15 | 2005-09-29 | Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipiid lowering activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002RM000016A ITRM20020016A1 (it) | 2002-01-15 | 2002-01-15 | Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza |
Publications (2)
Publication Number | Publication Date |
---|---|
ITRM20020016A0 true ITRM20020016A0 (it) | 2002-01-15 |
ITRM20020016A1 ITRM20020016A1 (it) | 2003-07-15 |
Family
ID=11455958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2002RM000016A ITRM20020016A1 (it) | 2002-01-15 | 2002-01-15 | Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza |
Country Status (15)
Country | Link |
---|---|
US (1) | US20050032787A1 (it) |
EP (1) | EP1465858A2 (it) |
JP (1) | JP2005514452A (it) |
KR (1) | KR100969979B1 (it) |
CN (1) | CN100509783C (it) |
AR (1) | AR038147A1 (it) |
AU (1) | AU2003209676B2 (it) |
BR (1) | BR0306880A (it) |
CA (1) | CA2472209A1 (it) |
HK (1) | HK1076628A1 (it) |
IT (1) | ITRM20020016A1 (it) |
MX (1) | MXPA04006802A (it) |
PL (1) | PL372616A1 (it) |
TW (1) | TW200302737A (it) |
WO (1) | WO2003059864A2 (it) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005016862A1 (en) * | 2003-08-14 | 2005-02-24 | Asahi Kasei Pharma Corporation | Substituted arylalkanoic acid derivative and use thereof |
EP1716144A2 (en) * | 2004-02-20 | 2006-11-02 | Synthon B.V. | Processes for making pioglitazone and compounds of the processes |
US20080125403A1 (en) | 2004-04-02 | 2008-05-29 | Merck & Co., Inc. | Method of Treating Men with Metabolic and Anthropometric Disorders |
WO2006029575A1 (en) * | 2004-09-17 | 2006-03-23 | Institute Of Mataria Medica, Chinese Academy Of Medical Sciences | NOVEL α-ALKYLOXY PROPIONIC ACIDS, THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USES |
TW200724138A (en) * | 2005-03-29 | 2007-07-01 | Sk Corp | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use |
ES2568516T3 (es) * | 2005-04-19 | 2016-04-29 | Merck Patent Gmbh | Antioxidantes |
BRPI0613429A2 (pt) | 2005-07-14 | 2009-02-10 | Takeda San Diego Inc | inibidores de histona desacetilase |
CA2647811A1 (en) * | 2006-03-30 | 2007-10-11 | Asahi Kasei Pharma Corporation | Substituted bicyclic derivative and use thereof |
KR101322116B1 (ko) * | 2006-07-20 | 2013-10-25 | 아사히 가세이 파마 가부시키가이샤 | 치환 페닐알칸산의 신규 결정 및 제조 방법 |
WO2009039944A1 (de) * | 2007-09-21 | 2009-04-02 | Sanofi-Aventis | Phenothiazin derivate mit doppelbindung, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
MY149648A (en) * | 2007-09-21 | 2013-09-30 | Sanofi Aventis | Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament |
JP5301468B2 (ja) * | 2008-01-18 | 2013-09-25 | 旭化成ファーマ株式会社 | 安定な医薬組成物 |
CA2722102C (en) * | 2008-04-28 | 2013-06-11 | Asahi Kasei Pharma Corporation | Phenylpropionic acid derivative and use thereof |
US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
MX2014004503A (es) | 2011-10-17 | 2015-01-16 | Biotheryx Inc | Biaril alquil amidas sustituidas. |
CN107858326B (zh) * | 2017-12-12 | 2021-08-20 | 上海银海圣生物科技有限公司 | 小鼠前脂肪细胞3t3-l1的诱导分化剂及诱导分化方法 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52116431A (en) * | 1976-03-24 | 1977-09-29 | Nippon Nohyaku Co Ltd | Phthalaminoic acid esters |
US4108632A (en) * | 1976-12-22 | 1978-08-22 | Monsanto Company | Use of phthalanilic acids to regulate the growth of corn plants |
US4094900A (en) * | 1977-05-19 | 1978-06-13 | Smithkline Corporation | Method of preparing aryloxybenzoic and arylthiobenzoic acids |
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
US4788054A (en) * | 1986-07-11 | 1988-11-29 | Stepan Company | N-phenylphthalisomides as ultraviolet radiation absorbers |
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
JP3053490B2 (ja) * | 1991-02-25 | 2000-06-19 | 杏林製薬株式会社 | チアゾリジン−2,4−ジオン誘導体とその塩及び製造法 |
FR2680512B1 (fr) * | 1991-08-20 | 1995-01-20 | Adir | Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5319096A (en) * | 1992-04-03 | 1994-06-07 | Hoechst-Roussel Pharmaceuticals Inc. | (1H-indol-1-yl)-2-(amino) acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, pharmaceutical composition and use |
US5232945A (en) * | 1992-07-20 | 1993-08-03 | Pfizer Inc. | 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives |
DK0638075T3 (da) * | 1993-02-26 | 2002-02-18 | Otsuka Pharma Co Ltd | Thiazol- eller imidazolderivater som Maillard-reaktionsinhibitorer |
CZ289317B6 (cs) * | 1994-04-11 | 2002-01-16 | Sankyo Company Limited | Heterocyklická sloučenina, farmaceutický prostředek ji obsahující a její pouľití |
JPH07330728A (ja) * | 1994-04-11 | 1995-12-19 | Sankyo Co Ltd | 複素環化合物 |
JP3144624B2 (ja) * | 1995-06-02 | 2001-03-12 | 杏林製薬株式会社 | N−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
US6001862A (en) * | 1995-06-02 | 1999-12-14 | Kyorin Pharameuticals Co., Ltd. | N-benzyldioxothiazolidylbenzamide derivatives and processes for preparing the same |
US6147101A (en) * | 1995-06-02 | 2000-11-14 | Kyorin Pharmaceutical Co., Ltd. | N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same |
GB9515975D0 (en) * | 1995-08-04 | 1995-10-04 | Zeneca Ltd | Chemical compounds |
JP3906935B2 (ja) * | 1995-12-18 | 2007-04-18 | 杏林製薬株式会社 | N−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
JPH09169709A (ja) * | 1995-12-21 | 1997-06-30 | Taisho Pharmaceut Co Ltd | ヘテロアルキル置換フェニルアルキルアミン誘導体 |
JP3215048B2 (ja) * | 1996-04-03 | 2001-10-02 | 日本たばこ産業株式会社 | プロピオン酸誘導体及びその用途 |
JPH09301963A (ja) * | 1996-05-17 | 1997-11-25 | Kyorin Pharmaceut Co Ltd | N−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
CZ53699A3 (cs) * | 1996-08-19 | 1999-07-14 | Japan Tobacco Inc. | Deriváty propionové kyseliny a jejich použití |
CA2294042A1 (en) * | 1997-06-26 | 1999-01-07 | David Kent Herron | Antithrombotic agents |
MA26634A1 (fr) * | 1998-06-04 | 2004-12-20 | Astra Ab | Nouveaux derives de l'acide 3-aryl propionique et analogues |
JP2000344748A (ja) * | 1999-03-29 | 2000-12-12 | Welfide Corp | 3−芳香族置換プロピオン酸またはアクリル酸化合物 |
CA2376919C (en) * | 1999-06-18 | 2008-11-04 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
TW574193B (en) * | 1999-12-03 | 2004-02-01 | Astrazeneca Ab | Novel phenalkyloxy-phenyl derivatives, pharmaceutical composition containing the same and their uses |
EP1217000A1 (en) * | 2000-12-23 | 2002-06-26 | Aventis Pharma Deutschland GmbH | Inhibitors of factor Xa and factor VIIa |
PL368051A1 (en) * | 2001-06-07 | 2005-03-21 | Eli Lilly And Company | Modulators of peroxisome proliferator activated receptors |
-
2002
- 2002-01-15 IT IT2002RM000016A patent/ITRM20020016A1/it unknown
-
2003
- 2003-01-13 AU AU2003209676A patent/AU2003209676B2/en not_active Ceased
- 2003-01-13 KR KR1020047010463A patent/KR100969979B1/ko not_active IP Right Cessation
- 2003-01-13 JP JP2003559969A patent/JP2005514452A/ja active Pending
- 2003-01-13 PL PL03372616A patent/PL372616A1/xx unknown
- 2003-01-13 US US10/501,135 patent/US20050032787A1/en not_active Abandoned
- 2003-01-13 BR BR0306880-3A patent/BR0306880A/pt not_active IP Right Cessation
- 2003-01-13 MX MXPA04006802A patent/MXPA04006802A/es active IP Right Grant
- 2003-01-13 CA CA002472209A patent/CA2472209A1/en not_active Abandoned
- 2003-01-13 CN CNB038022958A patent/CN100509783C/zh not_active Expired - Fee Related
- 2003-01-13 WO PCT/IT2003/000007 patent/WO2003059864A2/en active Application Filing
- 2003-01-13 EP EP03729544A patent/EP1465858A2/en not_active Withdrawn
- 2003-01-14 TW TW092100694A patent/TW200302737A/zh unknown
- 2003-01-15 AR ARP030100104A patent/AR038147A1/es unknown
-
2005
- 2005-09-29 HK HK05108580.4A patent/HK1076628A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TW200302737A (en) | 2003-08-16 |
AR038147A1 (es) | 2004-12-29 |
CN1617854A (zh) | 2005-05-18 |
WO2003059864A3 (en) | 2004-01-29 |
CN100509783C (zh) | 2009-07-08 |
PL372616A1 (en) | 2005-07-25 |
AU2003209676B2 (en) | 2009-06-11 |
KR100969979B1 (ko) | 2010-07-15 |
US20050032787A1 (en) | 2005-02-10 |
MXPA04006802A (es) | 2004-10-11 |
BR0306880A (pt) | 2004-12-21 |
CA2472209A1 (en) | 2003-07-24 |
JP2005514452A (ja) | 2005-05-19 |
KR20040081107A (ko) | 2004-09-20 |
HK1076628A1 (en) | 2006-01-20 |
EP1465858A2 (en) | 2004-10-13 |
WO2003059864A2 (en) | 2003-07-24 |
ITRM20020016A1 (it) | 2003-07-15 |
AU2003209676A1 (en) | 2003-07-30 |
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