ITMI971268A0 - - Google Patents
Info
- Publication number
- ITMI971268A0 ITMI971268A0 ITMI971268A ITMI971268A ITMI971268A0 IT MI971268 A0 ITMI971268 A0 IT MI971268A0 IT MI971268 A ITMI971268 A IT MI971268A IT MI971268 A ITMI971268 A IT MI971268A IT MI971268 A0 ITMI971268 A0 IT MI971268A0
- Authority
- IT
- Italy
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001268A IT1292037B1 (it) | 1997-05-30 | 1997-05-30 | Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen- |
| PT98928291T PT915835E (pt) | 1997-05-30 | 1998-05-19 | Processo para a preparacao de 5-¬acetil(2,3-di-hidroxipropil)amino|-n,n'-bis(2,3-dihidroxipropil)-3,4,6-triiodo-1,3-benzenodicarboxamida |
| DK98928291T DK0915835T3 (da) | 1997-05-30 | 1998-05-19 | Fremgangsmåde til fremstilling af 5-[acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiod-1,3-benze |
| JP50018399A JP3437584B2 (ja) | 1997-05-30 | 1998-05-19 | ５―［アセチル（２，３―ジヒドロキシプロピル）アミノ］―ｎ，ｎ′―ビス（２，３―ジヒドロキシプロピル）―２，４，６−トリヨード―１，３―ベンゼンジカルボキシアミドの製造方法 |
| AT98928291T ATE198191T1 (de) | 1997-05-30 | 1998-05-19 | Ein verfahren zur herstellung von 5-(acetyl(2,3- dihydroxypropyl)amino)-n,n'-bis(2,3- dihydroxypropyl)-2,4,6-triiodo-1,3-benzoldicar boxamid |
| AU80185/98A AU729759B2 (en) | 1997-05-30 | 1998-05-19 | A process for the preparation of 5-(acetyl (2,3-dihydroxypropyl)amino)-N,N'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide |
| PL98331208A PL331208A1 (en) | 1997-05-30 | 1998-05-19 | Method of obtaining 5-[acetyl (2,3-dihydroxypropyl)amino] -n,n' -bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzene dicarbamide |
| EP98928291A EP0915835B1 (en) | 1997-05-30 | 1998-05-19 | A process for the preparation of 5- acetyl (2,3-dihydroxypropyl)amino]-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide |
| DE69800434T DE69800434T2 (de) | 1997-05-30 | 1998-05-19 | Ein verfahren zur herstellung von 5-[acetyl(2,3-dihydroxypropyl)amino]-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzoldicar boxamid |
| CA002261656A CA2261656A1 (en) | 1997-05-30 | 1998-05-19 | A process for the preparation of 5-¬acetyl (2,3-dihydroxypropyl)amino|-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide |
| ES98928291T ES2152747T3 (es) | 1997-05-30 | 1998-05-19 | Un procedimiento para preparar 5-(acetil(2,3-dihidroxipropil)amino)-n,n'-bis(2,3-dihidroxipropil)-2,4,6-triyodo-1,3-bencenodicarboxamida. |
| PCT/EP1998/002927 WO1998054124A1 (en) | 1997-05-30 | 1998-05-19 | A process for the preparation of 5-[acetyl (2,3-dihydroxypropyl)amino]-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide |
| KR1019997000722A KR20000029649A (ko) | 1997-05-30 | 1998-05-19 | 5-[아세틸(2,3-디히드록시프로필)아미노]-ｎ,ｎ'-비스(2,3-디히드록시프로필)-2,4,6-트리요오도-1,3-벤젠디카르복스아미드의제조방법 |
| CN98800714A CN1228079A (zh) | 1997-05-30 | 1998-05-19 | 制备5－[乙酰基(2,3－二羟基丙基)氨基－n,n'－双(2,3－二羟基丙基)－2,4,6－三碘－1,3－苯二甲酰胺的方法 |
| CZ99253A CZ25399A3 (cs) | 1997-05-30 | 1998-05-19 | Způsob výroby trijodbenzendikarboxamidových derivátů |
| US09/084,922 US5965772A (en) | 1997-05-30 | 1998-05-28 | Process for the preparation of 5-(acetyl(2,3-dihydroxypropyl)amino-N,N-bis(2,3-dihydroxypropyl)-2,4,6-t riiodo |
| NO19990334A NO323475B1 (no) | 1997-05-30 | 1999-01-25 | Fremgangsmate ved fremstilling av 5-[acetyl(2,3-dihydroksypropyl)amino]-N,N'-bis(2,3-dihydroksypropyl)-2,4,6-triiod-1,3-benzendikarboksamid |
| GR20000402639T GR3035123T3 (en) | 1997-05-30 | 2000-12-21 | A process for the preparation of 5- acetyl (2,3-dihydroxypropyl)amino]-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001268A IT1292037B1 (it) | 1997-05-30 | 1997-05-30 | Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen- |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI971268A0 true ITMI971268A0 (US06559137-20030506-C00112.png) | 1997-05-30 |
| ITMI971268A1 ITMI971268A1 (it) | 1998-11-30 |
| IT1292037B1 IT1292037B1 (it) | 1999-01-25 |
Family
ID=11377250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT97MI001268A IT1292037B1 (it) | 1997-05-30 | 1997-05-30 | Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen- |
Country Status (18)
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE520688C2 (sv) * | 2000-04-11 | 2003-08-12 | Bone Support Ab | Ett injicerbart ersättningsmaterial för benmineral |
| SE517168C2 (sv) * | 2000-07-17 | 2002-04-23 | Bone Support Ab | En komposition för ett injicerbart ersättningsmaterial för benmineral |
| SE522098C2 (sv) | 2001-12-20 | 2004-01-13 | Bone Support Ab | Ett nytt benmineralsubstitut |
| SE0300620D0 (sv) | 2003-03-05 | 2003-03-05 | Bone Support Ab | A new bone substitute composition |
| WO2004087637A1 (en) * | 2003-03-31 | 2004-10-14 | Takasago International Corporation | Production of n-alkylamide compounds |
| SE0302983D0 (sv) * | 2003-11-11 | 2003-11-11 | Bone Support Ab | Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed |
| SE527528C2 (sv) | 2004-06-22 | 2006-04-04 | Bone Support Ab | Anordning för framställning av härdbar massa samt användning av anordningen |
| PT103391B (pt) * | 2005-11-24 | 2008-10-30 | Hovione Farmaciencia S A | Processo para fabrico de lohexol |
| CN100344606C (zh) * | 2005-12-28 | 2007-10-24 | 江苏省原子医学研究所 | 一种碘昔兰的制备方法 |
| JP5314671B2 (ja) * | 2007-04-25 | 2013-10-16 | エフ．ホフマン−ラ ロシュ アーゲー | 酸塩化物の新規合成方法 |
| CN101981001B (zh) | 2008-04-04 | 2016-06-08 | 弗·哈夫曼-拉罗切有限公司 | 制备环己烷甲酸衍生物的新方法 |
| ES2460900T3 (es) | 2008-04-04 | 2014-05-14 | F. Hoffmann-La Roche Ag | Nuevo procedimiento para la preparación de derivados de ácido ciclohexanocarboxílico mediante el correspondiente derivado ciclohexanocarboxamida |
| KR101098553B1 (ko) * | 2008-04-30 | 2011-12-26 | 주식회사 엘지생명과학 | 이오프로마이드의 신규한 제조방법 |
| AU2009259495B2 (en) | 2008-06-17 | 2014-04-03 | F. Hoffmann-La Roche Ag | 1-(2-ethyl-butyl) -cyclohexanecarboxylic acid ester as an intermediate in the preparation of pharmaceutically active amides |
| JP5536087B2 (ja) | 2008-11-18 | 2014-07-02 | ブラッコ・イメージング・ソシエタ・ペル・アチオニ | ヨウ化造影剤の製造方法 |
| BR112012012497B1 (pt) * | 2009-11-26 | 2021-09-08 | Hovione China Holding Limited | Método para preparar iodixanol |
| US9180137B2 (en) | 2010-02-09 | 2015-11-10 | Bone Support Ab | Preparation of bone cement compositions |
| IT1403988B1 (it) * | 2010-07-15 | 2013-11-08 | Bracco Imaging Spa | Processo per la preparazione di agenti di contrasto. |
| US10294107B2 (en) | 2013-02-20 | 2019-05-21 | Bone Support Ab | Setting of hardenable bone substitute |
| KR101520187B1 (ko) | 2013-10-25 | 2015-05-13 | 주식회사 대웅제약 | 이오프로마이드의 중간체의 제조방법 |
| CN106316878B (zh) * | 2015-06-15 | 2018-01-19 | 重庆常捷医药有限公司 | 一种碘美普尔杂质的制备方法 |
| CN110023279B (zh) | 2016-12-05 | 2022-03-11 | 伯拉考成像股份公司 | 放射照相剂中间体的机械化学合成 |
| KR102128423B1 (ko) * | 2018-09-17 | 2020-07-01 | (주)유케이케미팜 | 조영제 이오메프롤의 제조방법 |
| CN114478298B (zh) * | 2020-11-12 | 2024-09-27 | 成都西岭源药业有限公司 | 一种造影剂碘佛醇的纯化方法 |
| CN113387833A (zh) * | 2021-05-25 | 2021-09-14 | 成都丽璟科技有限公司 | 一种低渗透性泛影酸衍生物造影剂及其制备方法 |
| CN115872894A (zh) * | 2022-11-15 | 2023-03-31 | 上海慧聚药业有限公司 | 非离子型造影剂的合成 |
| CN116332787B (zh) * | 2023-03-03 | 2023-10-27 | 安庆朗坤药业有限公司 | 一种造影剂中间体乙酰碘化物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608189A5 (US06559137-20030506-C00112.png) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
| GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
| ATE176663T1 (de) * | 1995-05-23 | 1999-02-15 | Fructamine Spa | Verfahren zur herstellung von dicarbonsäurechlorid |
-
1997
- 1997-05-30 IT IT97MI001268A patent/IT1292037B1/it active IP Right Grant
-
1998
- 1998-05-19 EP EP98928291A patent/EP0915835B1/en not_active Expired - Lifetime
- 1998-05-19 CA CA002261656A patent/CA2261656A1/en not_active Abandoned
- 1998-05-19 DE DE69800434T patent/DE69800434T2/de not_active Expired - Lifetime
- 1998-05-19 CZ CZ99253A patent/CZ25399A3/cs unknown
- 1998-05-19 AU AU80185/98A patent/AU729759B2/en not_active Ceased
- 1998-05-19 AT AT98928291T patent/ATE198191T1/de not_active IP Right Cessation
- 1998-05-19 WO PCT/EP1998/002927 patent/WO1998054124A1/en not_active Application Discontinuation
- 1998-05-19 ES ES98928291T patent/ES2152747T3/es not_active Expired - Lifetime
- 1998-05-19 PT PT98928291T patent/PT915835E/pt unknown
- 1998-05-19 PL PL98331208A patent/PL331208A1/xx unknown
- 1998-05-19 CN CN98800714A patent/CN1228079A/zh active Pending
- 1998-05-19 JP JP50018399A patent/JP3437584B2/ja not_active Expired - Lifetime
- 1998-05-19 DK DK98928291T patent/DK0915835T3/da active
- 1998-05-19 KR KR1019997000722A patent/KR20000029649A/ko not_active Application Discontinuation
- 1998-05-28 US US09/084,922 patent/US5965772A/en not_active Expired - Lifetime
-
1999
- 1999-01-25 NO NO19990334A patent/NO323475B1/no not_active IP Right Cessation
-
2000
- 2000-12-21 GR GR20000402639T patent/GR3035123T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ25399A3 (cs) | 1999-07-14 |
| KR20000029649A (ko) | 2000-05-25 |
| DK0915835T3 (da) | 2001-02-05 |
| ITMI971268A1 (it) | 1998-11-30 |
| NO323475B1 (no) | 2007-05-21 |
| GR3035123T3 (en) | 2001-03-30 |
| CN1228079A (zh) | 1999-09-08 |
| PT915835E (pt) | 2001-03-30 |
| ATE198191T1 (de) | 2001-01-15 |
| EP0915835B1 (en) | 2000-12-20 |
| US5965772A (en) | 1999-10-12 |
| PL331208A1 (en) | 1999-07-05 |
| IT1292037B1 (it) | 1999-01-25 |
| CA2261656A1 (en) | 1998-12-03 |
| NO990334D0 (no) | 1999-01-25 |
| DE69800434T2 (de) | 2001-04-19 |
| WO1998054124A1 (en) | 1998-12-03 |
| ES2152747T3 (es) | 2001-02-01 |
| JP2000505820A (ja) | 2000-05-16 |
| AU729759B2 (en) | 2001-02-08 |
| EP0915835A1 (en) | 1999-05-19 |
| NO990334L (no) | 1999-03-26 |
| AU8018598A (en) | 1998-12-30 |
| DE69800434D1 (de) | 2001-01-25 |
| JP3437584B2 (ja) | 2003-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |