ITMI971268A0 - - Google Patents

Info

Publication number
ITMI971268A0
ITMI971268A0 ITMI971268A ITMI971268A ITMI971268A0 IT MI971268 A0 ITMI971268 A0 IT MI971268A0 IT MI971268 A ITMI971268 A IT MI971268A IT MI971268 A ITMI971268 A IT MI971268A IT MI971268 A0 ITMI971268 A0 IT MI971268A0
Authority
IT
Italy
Application number
ITMI971268A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ITMI971268A0 publication Critical patent/ITMI971268A0/it
Priority to IT97MI001268A priority Critical patent/IT1292037B1/it
Priority to AU80185/98A priority patent/AU729759B2/en
Priority to PCT/EP1998/002927 priority patent/WO1998054124A1/en
Priority to KR1019997000722A priority patent/KR20000029649A/ko
Priority to CN98800714A priority patent/CN1228079A/zh
Priority to DE69800434T priority patent/DE69800434T2/de
Priority to CZ99253A priority patent/CZ25399A3/cs
Priority to DK98928291T priority patent/DK0915835T3/da
Priority to JP50018399A priority patent/JP3437584B2/ja
Priority to EP98928291A priority patent/EP0915835B1/en
Priority to AT98928291T priority patent/ATE198191T1/de
Priority to PT98928291T priority patent/PT915835E/pt
Priority to CA002261656A priority patent/CA2261656A1/en
Priority to ES98928291T priority patent/ES2152747T3/es
Priority to PL98331208A priority patent/PL331208A1/xx
Priority to US09/084,922 priority patent/US5965772A/en
Publication of ITMI971268A1 publication Critical patent/ITMI971268A1/it
Priority to NO19990334A priority patent/NO323475B1/no
Application granted granted Critical
Publication of IT1292037B1 publication Critical patent/IT1292037B1/it
Priority to GR20000402639T priority patent/GR3035123T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
IT97MI001268A 1997-05-30 1997-05-30 Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen- IT1292037B1 (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT97MI001268A IT1292037B1 (it) 1997-05-30 1997-05-30 Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
JP50018399A JP3437584B2 (ja) 1997-05-30 1998-05-19 ５―［アセチル（２，３―ジヒドロキシプロピル）アミノ］―ｎ，ｎ′―ビス（２，３―ジヒドロキシプロピル）―２，４，６−トリヨード―１，３―ベンゼンジカルボキシアミドの製造方法
AT98928291T ATE198191T1 (de) 1997-05-30 1998-05-19 Ein verfahren zur herstellung von 5-(acetyl(2,3- dihydroxypropyl)amino)-n,n'-bis(2,3- dihydroxypropyl)-2,4,6-triiodo-1,3-benzoldicar boxamid
KR1019997000722A KR20000029649A (ko) 1997-05-30 1998-05-19 5-[아세틸(2,3-디히드록시프로필)아미노]-ｎ,ｎ'-비스(2,3-디히드록시프로필)-2,4,6-트리요오도-1,3-벤젠디카르복스아미드의제조방법
CN98800714A CN1228079A (zh) 1997-05-30 1998-05-19 制备5－[乙酰基(2,3－二羟基丙基)氨基－n,n'－双(2,3－二羟基丙基)－2,4,6－三碘－1,3－苯二甲酰胺的方法
DE69800434T DE69800434T2 (de) 1997-05-30 1998-05-19 Ein verfahren zur herstellung von 5-[acetyl(2,3-dihydroxypropyl)amino]-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzoldicar boxamid
CZ99253A CZ25399A3 (cs) 1997-05-30 1998-05-19 Způsob výroby trijodbenzendikarboxamidových derivátů
DK98928291T DK0915835T3 (da) 1997-05-30 1998-05-19 Fremgangsmåde til fremstilling af 5-[acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiod-1,3-benze
AU80185/98A AU729759B2 (en) 1997-05-30 1998-05-19 A process for the preparation of 5-(acetyl (2,3-dihydroxypropyl)amino)-N,N'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide
EP98928291A EP0915835B1 (en) 1997-05-30 1998-05-19 A process for the preparation of 5- acetyl (2,3-dihydroxypropyl)amino]-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide
PCT/EP1998/002927 WO1998054124A1 (en) 1997-05-30 1998-05-19 A process for the preparation of 5-[acetyl (2,3-dihydroxypropyl)amino]-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide
PT98928291T PT915835E (pt) 1997-05-30 1998-05-19 Processo para a preparacao de 5-¬acetil(2,3-di-hidroxipropil)amino|-n,n'-bis(2,3-dihidroxipropil)-3,4,6-triiodo-1,3-benzenodicarboxamida
CA002261656A CA2261656A1 (en) 1997-05-30 1998-05-19 A process for the preparation of 5-¬acetyl (2,3-dihydroxypropyl)amino|-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide
ES98928291T ES2152747T3 (es) 1997-05-30 1998-05-19 Un procedimiento para preparar 5-(acetil(2,3-dihidroxipropil)amino)-n,n'-bis(2,3-dihidroxipropil)-2,4,6-triyodo-1,3-bencenodicarboxamida.
PL98331208A PL331208A1 (en) 1997-05-30 1998-05-19 Method of obtaining 5-[acetyl (2,3-dihydroxypropyl)amino] -n,n' -bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzene dicarbamide
US09/084,922 US5965772A (en) 1997-05-30 1998-05-28 Process for the preparation of 5-(acetyl(2,3-dihydroxypropyl)amino-N,N-bis(2,3-dihydroxypropyl)-2,4,6-t riiodo
NO19990334A NO323475B1 (no) 1997-05-30 1999-01-25 Fremgangsmate ved fremstilling av 5-[acetyl(2,3-dihydroksypropyl)amino]-N,N'-bis(2,3-dihydroksypropyl)-2,4,6-triiod-1,3-benzendikarboksamid
GR20000402639T GR3035123T3 (en) 1997-05-30 2000-12-21 A process for the preparation of 5- acetyl (2,3-dihydroxypropyl)amino]-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001268A IT1292037B1 (it) 1997-05-30 1997-05-30 Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-

Publications (3)

Publication Number Publication Date
ITMI971268A0 true ITMI971268A0 (it) 1997-05-30
ITMI971268A1 ITMI971268A1 (it) 1998-11-30
IT1292037B1 IT1292037B1 (it) 1999-01-25

Family

ID=11377250

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI001268A IT1292037B1 (it) 1997-05-30 1997-05-30 Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-

Country Status (18)

Country Link
US (1) US5965772A (it)
EP (1) EP0915835B1 (it)
JP (1) JP3437584B2 (it)
KR (1) KR20000029649A (it)
CN (1) CN1228079A (it)
AT (1) ATE198191T1 (it)
AU (1) AU729759B2 (it)
CA (1) CA2261656A1 (it)
CZ (1) CZ25399A3 (it)
DE (1) DE69800434T2 (it)
DK (1) DK0915835T3 (it)
ES (1) ES2152747T3 (it)
GR (1) GR3035123T3 (it)
IT (1) IT1292037B1 (it)
NO (1) NO323475B1 (it)
PL (1) PL331208A1 (it)
PT (1) PT915835E (it)
WO (1) WO1998054124A1 (it)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE520688C2 (sv) * 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) * 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
WO2004087637A1 (en) * 2003-03-31 2004-10-14 Takasago International Corporation Production of n-alkylamide compounds
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
PT103391B (pt) * 2005-11-24 2008-10-30 Hovione Farmaciencia S A Processo para fabrico de lohexol
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
CA2684067A1 (en) 2007-04-25 2008-11-06 F. Hoffmann-La Roche Ag Novel process for the preparation of acid chlorides
ES2592727T3 (es) 2008-04-04 2016-12-01 F. Hoffmann-La Roche Ag Nuevo proceso para la preparación de derivados del ácido ciclohexanocarboxílico
MX2010009876A (es) 2008-04-04 2010-09-28 Hoffmann La Roche Nuevo proceso para la preparacion de derivados de acido ciclohexanocarboxilico por medio del derivado de ciclohexanocarboxamida correspondiente.
KR101098553B1 (ko) * 2008-04-30 2011-12-26 주식회사 엘지생명과학 이오프로마이드의 신규한 제조방법
MX2010013403A (es) 2008-06-17 2010-12-22 Hoffmann La Roche Ester del acido 1-(2-etil-butil)-ciclohexanocarboxilico como un intermediario en la preparacion de amidas farmaceuticamente activas.
AU2009317450B2 (en) 2008-11-18 2015-05-07 Bracco Imaging Spa Process for the preparation of iodinated contrast agent
JP5775524B2 (ja) * 2009-11-26 2015-09-09 アイマックス ダイアグノスティック イメージング ホールディング リミテッド イオジキサノールの調製及び精製
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
US10294107B2 (en) 2013-02-20 2019-05-21 Bone Support Ab Setting of hardenable bone substitute
KR101520187B1 (ko) 2013-10-25 2015-05-13 주식회사 대웅제약 이오프로마이드의 중간체의 제조방법
CN106316878B (zh) * 2015-06-15 2018-01-19 重庆常捷医药有限公司 一种碘美普尔杂质的制备方法
EP3548461B1 (en) 2016-12-05 2021-02-03 Bracco Imaging SpA Mechanochemical synthesis of radiographic agents intermediates
KR102128423B1 (ko) * 2018-09-17 2020-07-01 (주)유케이케미팜 조영제 이오메프롤의 제조방법
CN114478298A (zh) * 2020-11-12 2022-05-13 成都西岭源药业有限公司 一种造影剂碘佛醇的纯化方法
CN113387833A (zh) * 2021-05-25 2021-09-14 成都丽璟科技有限公司 一种低渗透性泛影酸衍生物造影剂及其制备方法
CN115872894A (zh) * 2022-11-15 2023-03-31 上海慧聚药业有限公司 非离子型造影剂的合成
CN116332787B (zh) * 2023-03-03 2023-10-27 安庆朗坤药业有限公司 一种造影剂中间体乙酰碘化物的制备方法

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CH608189A5 (it) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
US5616795A (en) * 1995-05-23 1997-04-01 Fructamine S.P.A. Process for the preparation of a dicarboxylic acid dichloride

Also Published As

Publication number Publication date
NO990334D0 (no) 1999-01-25
JP2000505820A (ja) 2000-05-16
IT1292037B1 (it) 1999-01-25
CZ25399A3 (cs) 1999-07-14
US5965772A (en) 1999-10-12
GR3035123T3 (en) 2001-03-30
CA2261656A1 (en) 1998-12-03
PT915835E (pt) 2001-03-30
ES2152747T3 (es) 2001-02-01
DK0915835T3 (da) 2001-02-05
ATE198191T1 (de) 2001-01-15
PL331208A1 (en) 1999-07-05
DE69800434D1 (de) 2001-01-25
KR20000029649A (ko) 2000-05-25
ITMI971268A1 (it) 1998-11-30
NO990334L (no) 1999-03-26
AU8018598A (en) 1998-12-30
JP3437584B2 (ja) 2003-08-18
EP0915835B1 (en) 2000-12-20
NO323475B1 (no) 2007-05-21
AU729759B2 (en) 2001-02-08
EP0915835A1 (en) 1999-05-19
WO1998054124A1 (en) 1998-12-03
CN1228079A (zh) 1999-09-08
DE69800434T2 (de) 2001-04-19

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Legal Events

Date Code Title Description
0001 Granted