ITMI20121489A1 - Metodo per la riduzione di nitro derivati ad ammine - Google Patents

Metodo per la riduzione di nitro derivati ad ammine Download PDF

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Publication number
ITMI20121489A1
ITMI20121489A1 IT001489A ITMI20121489A ITMI20121489A1 IT MI20121489 A1 ITMI20121489 A1 IT MI20121489A1 IT 001489 A IT001489 A IT 001489A IT MI20121489 A ITMI20121489 A IT MI20121489A IT MI20121489 A1 ITMI20121489 A1 IT MI20121489A1
Authority
IT
Italy
Prior art keywords
nitro group
base
compound
reduction
present
Prior art date
Application number
IT001489A
Other languages
English (en)
Italian (it)
Inventor
Maurizio Benaglia
Martina Bonsignore
Original Assignee
Univ Degli Studi Milano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Milano filed Critical Univ Degli Studi Milano
Priority to IT001489A priority Critical patent/ITMI20121489A1/it
Priority to PCT/EP2013/068371 priority patent/WO2014037444A1/en
Priority to CN201380056114.1A priority patent/CN104822642B/zh
Priority to CA2884114A priority patent/CA2884114C/en
Priority to SI201330516A priority patent/SI2892862T1/sl
Priority to MX2015003039A priority patent/MX373769B/es
Priority to KR1020157008317A priority patent/KR102074540B1/ko
Priority to JP2015530387A priority patent/JP6147345B2/ja
Priority to EP13766240.9A priority patent/EP2892862B1/en
Priority to PL13766240T priority patent/PL2892862T3/pl
Priority to DK13766240.9T priority patent/DK2892862T3/en
Priority to US14/426,221 priority patent/US9284258B2/en
Priority to ES13766240.9T priority patent/ES2614243T3/es
Priority to HUE13766240A priority patent/HUE032256T2/en
Priority to HRP20170204TT priority patent/HRP20170204T1/hr
Priority to IN2567DEN2015 priority patent/IN2015DN02567A/en
Priority to PT137662409T priority patent/PT2892862T/pt
Publication of ITMI20121489A1 publication Critical patent/ITMI20121489A1/it
Priority to IL237616A priority patent/IL237616A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/325—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups reduction by other means than indicated in C07C209/34 or C07C209/36
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B43/00—Formation or introduction of functional groups containing nitrogen
    • C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/34—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
    • C07C209/365—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst by reduction with preservation of halogen-atoms in compounds containing nitro groups and halogen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT001489A 2012-09-06 2012-09-06 Metodo per la riduzione di nitro derivati ad ammine ITMI20121489A1 (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT001489A ITMI20121489A1 (it) 2012-09-06 2012-09-06 Metodo per la riduzione di nitro derivati ad ammine
PL13766240T PL2892862T3 (pl) 2012-09-06 2013-09-05 proces redukcji pochodnych nitro do amin
DK13766240.9T DK2892862T3 (en) 2012-09-06 2013-09-05 METHOD OF REDUCING NITRODE DERIVATIVES TO AMINES
CA2884114A CA2884114C (en) 2012-09-06 2013-09-05 Process for the reduction of nitro derivatives to amines by trichlorosilane in presence of an organic base
SI201330516A SI2892862T1 (sl) 2012-09-06 2013-09-05 Postopek za redukcijo nitro derivatov v amine
MX2015003039A MX373769B (es) 2012-09-06 2013-09-05 Proceso para la reducción de derivados nitro a aminas.
KR1020157008317A KR102074540B1 (ko) 2012-09-06 2013-09-05 니트로 유도체를 아민으로 환원시키기 위한 방법
JP2015530387A JP6147345B2 (ja) 2012-09-06 2013-09-05 ニトロ誘導体からアミンへの還元方法
EP13766240.9A EP2892862B1 (en) 2012-09-06 2013-09-05 Process for the reduction of nitro derivatives to amines
PCT/EP2013/068371 WO2014037444A1 (en) 2012-09-06 2013-09-05 Process for the reduction of nitro derivatives to amines
CN201380056114.1A CN104822642B (zh) 2012-09-06 2013-09-05 将硝基衍生物还原成胺的方法
US14/426,221 US9284258B2 (en) 2012-09-06 2013-09-05 Process for the reduction of nitro derivatives to amines
ES13766240.9T ES2614243T3 (es) 2012-09-06 2013-09-05 Proceso para la reducción de derivados nitro a aminas
HUE13766240A HUE032256T2 (en) 2012-09-06 2013-09-05 Process for the reduction of nitro derivatives to amines
HRP20170204TT HRP20170204T1 (hr) 2012-09-06 2013-09-05 Postupak za redukciju nitro-derivata u amine
IN2567DEN2015 IN2015DN02567A (enExample) 2012-09-06 2013-09-05
PT137662409T PT2892862T (pt) 2012-09-06 2013-09-05 Processo para a redução de derivados de nitro em aminas
IL237616A IL237616A (en) 2012-09-06 2015-03-08 Process for converting nitro derivatives to amines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001489A ITMI20121489A1 (it) 2012-09-06 2012-09-06 Metodo per la riduzione di nitro derivati ad ammine

Publications (1)

Publication Number Publication Date
ITMI20121489A1 true ITMI20121489A1 (it) 2014-03-07

Family

ID=47046692

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001489A ITMI20121489A1 (it) 2012-09-06 2012-09-06 Metodo per la riduzione di nitro derivati ad ammine

Country Status (18)

Country Link
US (1) US9284258B2 (enExample)
EP (1) EP2892862B1 (enExample)
JP (1) JP6147345B2 (enExample)
KR (1) KR102074540B1 (enExample)
CN (1) CN104822642B (enExample)
CA (1) CA2884114C (enExample)
DK (1) DK2892862T3 (enExample)
ES (1) ES2614243T3 (enExample)
HR (1) HRP20170204T1 (enExample)
HU (1) HUE032256T2 (enExample)
IL (1) IL237616A (enExample)
IN (1) IN2015DN02567A (enExample)
IT (1) ITMI20121489A1 (enExample)
MX (1) MX373769B (enExample)
PL (1) PL2892862T3 (enExample)
PT (1) PT2892862T (enExample)
SI (1) SI2892862T1 (enExample)
WO (1) WO2014037444A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2933242A1 (en) * 2014-04-16 2015-10-21 Basf Se Process for manufacturing amino compounds
JP2016117688A (ja) * 2014-12-22 2016-06-30 東レ・ファインケミカル株式会社 ジアミン化合物の製造方法
CN108484522A (zh) * 2018-04-25 2018-09-04 山东百诺医药股份有限公司 4-(1,2,4-噁二唑-3-基)苯胺的制备方法
CN109053585B (zh) * 2018-09-13 2020-10-23 暨明医药科技（苏州）有限公司 一种三氯苯达唑的合成方法
CN111777576A (zh) * 2019-04-05 2020-10-16 齐鲁制药有限公司 尼达尼布关键中间体的制备方法
CN113354543A (zh) * 2020-03-03 2021-09-07 深圳有为技术控股集团有限公司 若干硝基化合物的硅烷化学还原制备胺基产物及h-酸的新环保生产工艺
CN112010801B (zh) * 2020-10-16 2023-07-28 山东汇海医药化工有限公司 一种氨氯地平碱的制备方法
US20230357125A1 (en) * 2022-05-06 2023-11-09 AMPAC Fine Chemicals Process for Catalytic Reduction of Nitro Compounds to Amines
CN117164471A (zh) * 2023-08-14 2023-12-05 河北圣雪大成制药有限责任公司 一种由9-氨基米诺环素制备替加环素的方法
CN117820127B (zh) * 2023-12-14 2025-11-28 清源创新实验室 一种芳香胺类化合物的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485875A (en) * 1967-06-28 1969-12-23 Texaco Inc Production of primary amines
WO2011016052A2 (en) * 2009-08-03 2011-02-10 Helvetica Industries (P) Limited Process for preparing pregabalin

Family Cites Families (7)

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JPH1036300A (ja) * 1996-07-18 1998-02-10 Souzou Kagaku Kenkyusho:Kk トリクロロシラン還元によるアルコールおよびアミンの製造方法
US6162929A (en) * 1997-12-23 2000-12-19 Hoffmann-La Roche Inc. Process for the manufacture of bisphosphine oxide and bisphosphonate compounds
JP2000256305A (ja) * 1999-03-10 2000-09-19 Sumitomo Chem Co Ltd 光学活性アミン化合物の製造法
JP2001270851A (ja) * 2000-03-24 2001-10-02 Tokuyama Corp 含窒素化合物の製造方法
JP2004307369A (ja) * 2003-04-03 2004-11-04 Seiko Epson Corp ４−フェニルベンゾフェノン誘導体および４−フェニルベンゾフェノン誘導体の製造方法
KR101189935B1 (ko) * 2004-05-11 2012-10-12 홍콩 폴리테크닉 유니버시티 전이 금속 촉매화 반응의 리간드
JP5008063B2 (ja) * 2006-11-22 2012-08-22 独立行政法人産業技術総合研究所 ジホスフィンコア型両親媒性デンドリマー、その製造方法、二座ホスフィン配位子及びその配位構造を有する含パラジウム錯体化合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485875A (en) * 1967-06-28 1969-12-23 Texaco Inc Production of primary amines
WO2011016052A2 (en) * 2009-08-03 2011-02-10 Helvetica Industries (P) Limited Process for preparing pregabalin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MANDAL ET AL.: "Pd-C-Induced Catalytic Transfer Hydrogenation with Triethylsilane", J. ORG. CHEM., vol. 72, 2007, pages 6599 - 6601, XP002692056 *

Also Published As

Publication number Publication date
JP6147345B2 (ja) 2017-06-14
SI2892862T1 (sl) 2017-06-30
MX373769B (es) 2020-04-10
EP2892862B1 (en) 2016-11-09
PL2892862T3 (pl) 2017-07-31
US9284258B2 (en) 2016-03-15
IL237616A0 (en) 2015-04-30
ES2614243T3 (es) 2017-05-30
HUE032256T2 (en) 2017-09-28
PT2892862T (pt) 2017-02-10
MX2015003039A (es) 2015-09-21
KR102074540B1 (ko) 2020-02-06
US20150232412A1 (en) 2015-08-20
CA2884114C (en) 2020-08-18
IL237616A (en) 2017-03-30
WO2014037444A1 (en) 2014-03-13
KR20150060740A (ko) 2015-06-03
EP2892862A1 (en) 2015-07-15
DK2892862T3 (en) 2017-02-20
HRP20170204T1 (hr) 2017-06-02
CN104822642A (zh) 2015-08-05
JP2015527381A (ja) 2015-09-17
CN104822642B (zh) 2016-08-24
IN2015DN02567A (enExample) 2015-09-11
CA2884114A1 (en) 2014-03-13

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