IT1116654B - Metodo per la produzione di gona-4,9 10 dieni - Google Patents

Metodo per la produzione di gona-4,9 10 dieni

Info

Publication number
IT1116654B
IT1116654B IT49669/77A IT4966977A IT1116654B IT 1116654 B IT1116654 B IT 1116654B IT 49669/77 A IT49669/77 A IT 49669/77A IT 4966977 A IT4966977 A IT 4966977A IT 1116654 B IT1116654 B IT 1116654B
Authority
IT
Italy
Prior art keywords
dieni
gona
production
Prior art date
Application number
IT49669/77A
Other languages
English (en)
Italian (it)
Inventor
Ponsold Kurt
Hubner Michael
Oettel Michael
Original Assignee
Jenapharm Veb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DD7600193348A external-priority patent/DD132497A1/xx
Application filed by Jenapharm Veb filed Critical Jenapharm Veb
Application granted granted Critical
Publication of IT1116654B publication Critical patent/IT1116654B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT49669/77A 1976-06-14 1977-06-01 Metodo per la produzione di gona-4,9 10 dieni IT1116654B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD7600193348A DD132497A1 (de) 1976-06-14 1976-06-14 Verfahren zur herstellung von neuen gona-4,9(10)-dienen

Publications (1)

Publication Number Publication Date
IT1116654B true IT1116654B (it) 1986-02-10

Family

ID=5504816

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49669/77A IT1116654B (it) 1976-06-14 1977-06-01 Metodo per la produzione di gona-4,9 10 dieni

Country Status (18)

Country Link
US (1) US4248790A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5312849A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE855617A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR7703832A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH635594A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2718872A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK259477A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES461987A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI57113C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2393008A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1524917A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU177333B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1116654B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX4685E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL187167C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (2) NO145244C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE426833B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU39804B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6322598A (ja) * 1986-07-14 1988-01-30 Mitsubishi Chem Ind Ltd ゴナトリエン誘導体およびその製造法
HU201091B (en) 1985-12-26 1990-09-28 Mitsubishi Chem Ind Process for producing gonatriene derivatives and pharmaceutical compositions comprising same
JPS6372627A (ja) * 1986-09-17 1988-04-02 Mitsubishi Kasei Corp 子宮内膜症治療薬
JPH0780335B2 (ja) * 1989-11-20 1995-08-30 富士通株式会社 リボンカセット
DK0654267T3 (da) * 1993-11-19 2002-05-13 Jenapharm Gmbh Carcinostatisk middel til hormonterapi indeholdende dienogest som aktiv komponent
ES2120267T3 (es) * 1995-12-22 1998-10-16 Jenapharm Gmbh Nuevos derivados de 17alfa-cianometilestra-4,9-dieno, un proceso para su preparacion y composiciones farmaceuticas que los contienen.
US6479475B1 (en) 1996-07-26 2002-11-12 Wyeth Oral contraceptive
US5858405A (en) * 1996-07-26 1999-01-12 American Home Products Corporation Oral contraceptive
US5888543A (en) * 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
US6451778B1 (en) 1996-07-26 2002-09-17 Wyeth Oral contraceptive
HUP0501132A2 (en) * 2005-12-05 2007-06-28 Richter Gedeon Nyrt 17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
ATE536362T1 (de) * 2009-05-22 2011-12-15 Heyl Chem Pharm Verfahren zur synthese von dienogest aus estron-3-methylether
EP2560984B1 (en) 2010-04-20 2015-04-01 Lupin Limited Process for the preparation of dienogest substantially free of impurities
CN112724191B (zh) * 2020-12-30 2022-11-15 上海汇伦医药股份有限公司 一种地诺孕素的精制方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502699A (en) * 1962-05-15 1970-03-24 Herchel Smith Novel delta4,9-3-ketosteroids and method for preparing same
DE1214223B (de) * 1962-11-22 1966-04-14 Roussel Uclaf Verfahren zur Herstellung von Hydroxy-hydroxymethyl-steroiden
US3624110A (en) * 1964-08-03 1971-11-30 Herchel Smith 13-ethylgona-4,9-dienes
GB1130881A (en) * 1964-08-06 1968-10-16 Merck & Co Inc Steroidal-í¸-dien-3-ones and derivatives thereof
FR2031807A5 (en) * 1969-02-07 1970-11-20 Jenapharm Veb 17a-subst estratrienes
US3931154A (en) * 1973-07-07 1976-01-06 Schering Aktiengesellschaft Process for the preparation of steroid oxiranes
US4029648A (en) * 1976-01-15 1977-06-14 Veb Jenapharm Process of making gona-1,3,5(10),9(11)-tetraenes

Also Published As

Publication number Publication date
SE7706835L (sv) 1978-01-15
NO146574B (no) 1982-07-19
NO146574C (no) 1982-10-27
NL7706465A (nl) 1977-12-16
FI57113C (fi) 1980-06-10
YU39804B (en) 1985-04-30
YU146577A (en) 1982-06-30
ES461987A3 (es) 1978-06-01
HU177333B (en) 1981-09-28
DE2718872C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-12-10
NO145244B (no) 1981-11-02
NO772054L (no) 1977-12-15
GB1524917A (en) 1978-09-13
FI771865A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-12-15
BR7703832A (pt) 1978-04-25
BE855617A (fr) 1977-12-13
FI57113B (fi) 1980-02-29
JPS5312849A (en) 1978-02-04
DE2718872A1 (de) 1977-12-22
DK259477A (da) 1977-12-15
NL187167B (nl) 1991-01-16
NO145244C (no) 1982-02-10
NL187167C (nl) 1991-06-17
MX4685E (es) 1982-07-30
SE426833B (sv) 1983-02-14
JPS616838B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-03-01
CH635594A5 (de) 1983-04-15
FR2393008B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-05-07
FR2393008A1 (fr) 1978-12-29
US4248790A (en) 1981-02-03
NO811764L (no) 1977-12-15

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19951228