IS7882A - Aðferð til að framleiða 2,6-díamínó-4,5,6,7-tetrahýdró-benzóþíazól - Google Patents

Aðferð til að framleiða 2,6-díamínó-4,5,6,7-tetrahýdró-benzóþíazól

Info

Publication number
IS7882A
IS7882A IS7882A IS7882A IS7882A IS 7882 A IS7882 A IS 7882A IS 7882 A IS7882 A IS 7882A IS 7882 A IS7882 A IS 7882A IS 7882 A IS7882 A IS 7882A
Authority
IS
Iceland
Prior art keywords
benzothiazole
diamino
tetrahydro
producing
Prior art date
Application number
IS7882A
Other languages
English (en)
Inventor
Ramachandra Rao Dharmaraj
Narayanrao Kankan Rajendra
Original Assignee
Cipla Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd. filed Critical Cipla Ltd.
Publication of IS7882A publication Critical patent/IS7882A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS7882A 2002-11-04 2005-06-02 Aðferð til að framleiða 2,6-díamínó-4,5,6,7-tetrahýdró-benzóþíazól IS7882A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0225701A GB2394951A (en) 2002-11-04 2002-11-04 One pot synthesis of 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole
PCT/GB2003/004734 WO2004041797A1 (en) 2002-11-04 2003-11-03 Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole

Publications (1)

Publication Number Publication Date
IS7882A true IS7882A (is) 2005-06-02

Family

ID=9947186

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7882A IS7882A (is) 2002-11-04 2005-06-02 Aðferð til að framleiða 2,6-díamínó-4,5,6,7-tetrahýdró-benzóþíazól

Country Status (25)

Country Link
US (1) US7285669B2 (is)
EP (1) EP1562921B1 (is)
JP (1) JP4708792B2 (is)
KR (1) KR101086844B1 (is)
CN (1) CN100551918C (is)
AP (1) AP1882A (is)
AT (1) ATE396180T1 (is)
AU (1) AU2003278396B2 (is)
BR (1) BR0315919A (is)
CA (1) CA2505179C (is)
DE (1) DE60321208D1 (is)
EC (1) ECSP055835A (is)
GB (1) GB2394951A (is)
HR (1) HRPK20050403B3 (is)
IS (1) IS7882A (is)
MA (1) MA27534A1 (is)
MX (1) MXPA05004815A (is)
NO (1) NO20052189L (is)
NZ (1) NZ539953A (is)
PL (1) PL376543A1 (is)
PT (1) PT1562921E (is)
RU (1) RU2305097C2 (is)
TN (1) TNSN05125A1 (is)
WO (1) WO2004041797A1 (is)
ZA (1) ZA200503548B (is)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0221513D0 (en) * 2002-09-17 2002-10-23 Generics Uk Ltd Novel compounds and processes
WO2006012277A2 (en) * 2004-06-30 2006-02-02 Amr Technology, Inc. Biocatalytic process for preparing enantiomerically enriched pramipexole
WO2006003677A1 (en) * 2004-07-01 2006-01-12 Alembic Limited Improved process for the preparation of biologically active tetrahydrobenzthiazole derivative
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
CN101448498B (zh) 2006-05-16 2011-04-27 诺普神经科学股份有限公司 R(+)和s(-)普拉克索的组合物以及使用该组合物的方法
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
SI22446A (sl) * 2007-02-07 2008-08-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek za sintezo pramipeksola in njegovih farmacevtsko sprejemljivih soli
WO2008104847A2 (en) * 2007-02-26 2008-09-04 Wockhardt Research Centre Processes for the preparation of pramipexole and salts thereof
US8519148B2 (en) 2007-03-14 2013-08-27 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
CN101429173B (zh) * 2007-11-09 2012-12-05 重庆医药工业研究院有限责任公司 一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢-苯并噻唑的制备方法
CN102186350A (zh) 2008-08-19 2011-09-14 诺普神经科学股份有限公司 使用(r)-普拉克索的组合物与方法
WO2011021214A2 (en) * 2009-08-07 2011-02-24 Msn Laboratories Limited Improved process for the preparation of (s)-2-amino-4,5,6,7-tetrahydro-6 - (propylamino) benzothiazole and its pharmaceutically acceptable salts
US9512096B2 (en) 2011-12-22 2016-12-06 Knopp Biosciences, LLP Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
EP3838271A1 (en) 2013-07-12 2021-06-23 Knopp Biosciences LLC Treating elevated levels of eosinophils and/or basophils
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
CA2921378A1 (en) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
DK3033081T3 (da) 2013-08-13 2021-05-31 Knopp Biosciences Llc Sammensætninger og fremgangsmåder til behandling af kronisk urticaria
CN104311507A (zh) * 2013-10-09 2015-01-28 安徽万邦医药科技有限公司 (6s)-2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法
CN103613562B (zh) * 2013-11-25 2015-09-30 浙江美诺华药物化学有限公司 一种普拉克索的制备方法
CN107573301B (zh) * 2017-11-08 2020-08-11 江苏长青农化股份有限公司 一种三环唑中间体的制备方法
CN109232471B (zh) * 2018-10-31 2022-05-10 安徽省庆云医药股份有限公司 一种盐酸普拉克索的制备方法
CN111362884A (zh) * 2018-12-26 2020-07-03 江苏神龙药业股份有限公司 一种2,6-二氨基-4,5,6,7-四氢-苯并噻唑的工业化制备方法
CN110734413A (zh) * 2019-12-02 2020-01-31 山东铂源药业有限公司 一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3572485D1 (en) * 1984-12-22 1989-09-28 Thomae Gmbh Dr K Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs
DE3447075A1 (de) * 1984-12-22 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
ES2187249B1 (es) * 2000-09-18 2004-09-16 Synthon Bv Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.

Also Published As

Publication number Publication date
NZ539953A (en) 2007-11-30
CA2505179C (en) 2012-10-16
GB2394951A (en) 2004-05-12
WO2004041797A1 (en) 2004-05-21
HRP20050403A2 (en) 2005-12-31
CN1735604A (zh) 2006-02-15
AU2003278396A1 (en) 2004-06-07
EP1562921B1 (en) 2008-05-21
GB0225701D0 (en) 2002-12-11
JP2006506412A (ja) 2006-02-23
AU2003278396B2 (en) 2010-04-01
DE60321208D1 (de) 2008-07-03
AP1882A (en) 2008-08-21
AP2005003306A0 (en) 2005-06-30
PL376543A1 (pl) 2006-01-09
ATE396180T1 (de) 2008-06-15
CA2505179A1 (en) 2004-05-21
KR101086844B1 (ko) 2011-11-24
CN100551918C (zh) 2009-10-21
HRPK20050403B3 (en) 2007-05-31
MA27534A1 (fr) 2005-09-01
ZA200503548B (en) 2006-12-27
TNSN05125A1 (en) 2007-05-14
KR20050072474A (ko) 2005-07-11
ECSP055835A (es) 2005-11-22
PT1562921E (pt) 2008-06-11
US20060100256A1 (en) 2006-05-11
NO20052189L (no) 2005-06-03
BR0315919A (pt) 2005-09-20
US7285669B2 (en) 2007-10-23
RU2305097C2 (ru) 2007-08-27
EP1562921A1 (en) 2005-08-17
RU2005117364A (ru) 2006-02-27
JP4708792B2 (ja) 2011-06-22
MXPA05004815A (es) 2005-08-18

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