PL376543A1 - Sposób wytwarzania 2,6-diamino-4,5,6,7-tetrahydrobenzotiazolu - Google Patents
Sposób wytwarzania 2,6-diamino-4,5,6,7-tetrahydrobenzotiazoluInfo
- Publication number
- PL376543A1 PL376543A1 PL376543A PL37654303A PL376543A1 PL 376543 A1 PL376543 A1 PL 376543A1 PL 376543 A PL376543 A PL 376543A PL 37654303 A PL37654303 A PL 37654303A PL 376543 A1 PL376543 A1 PL 376543A1
- Authority
- PL
- Poland
- Prior art keywords
- benzothiazole
- diamino
- tetrahydro
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0225701A GB2394951A (en) | 2002-11-04 | 2002-11-04 | One pot synthesis of 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole |
Publications (1)
Publication Number | Publication Date |
---|---|
PL376543A1 true PL376543A1 (pl) | 2006-01-09 |
Family
ID=9947186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL376543A PL376543A1 (pl) | 2002-11-04 | 2003-11-03 | Sposób wytwarzania 2,6-diamino-4,5,6,7-tetrahydrobenzotiazolu |
Country Status (25)
Country | Link |
---|---|
US (1) | US7285669B2 (pl) |
EP (1) | EP1562921B1 (pl) |
JP (1) | JP4708792B2 (pl) |
KR (1) | KR101086844B1 (pl) |
CN (1) | CN100551918C (pl) |
AP (1) | AP1882A (pl) |
AT (1) | ATE396180T1 (pl) |
AU (1) | AU2003278396B2 (pl) |
BR (1) | BR0315919A (pl) |
CA (1) | CA2505179C (pl) |
DE (1) | DE60321208D1 (pl) |
EC (1) | ECSP055835A (pl) |
GB (1) | GB2394951A (pl) |
HR (1) | HRPK20050403B3 (pl) |
IS (1) | IS7882A (pl) |
MA (1) | MA27534A1 (pl) |
MX (1) | MXPA05004815A (pl) |
NO (1) | NO20052189L (pl) |
NZ (1) | NZ539953A (pl) |
PL (1) | PL376543A1 (pl) |
PT (1) | PT1562921E (pl) |
RU (1) | RU2305097C2 (pl) |
TN (1) | TNSN05125A1 (pl) |
WO (1) | WO2004041797A1 (pl) |
ZA (1) | ZA200503548B (pl) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0221513D0 (en) * | 2002-09-17 | 2002-10-23 | Generics Uk Ltd | Novel compounds and processes |
WO2006012277A2 (en) * | 2004-06-30 | 2006-02-02 | Amr Technology, Inc. | Biocatalytic process for preparing enantiomerically enriched pramipexole |
CA2553311A1 (en) * | 2004-07-01 | 2006-01-12 | Alembic Limited | Improved process for the preparation of biologically active tetrahydrobenzthiazole derivative |
US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
JP2009537565A (ja) | 2006-05-16 | 2009-10-29 | ノップ ニューロサイエンシーズ、インク. | R(+)およびs(−)プラミペキソール組成とそれを利用する方法 |
US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
SI22446A (sl) * | 2007-02-07 | 2008-08-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek za sintezo pramipeksola in njegovih farmacevtsko sprejemljivih soli |
WO2008104847A2 (en) * | 2007-02-26 | 2008-09-04 | Wockhardt Research Centre | Processes for the preparation of pramipexole and salts thereof |
RU2454409C2 (ru) | 2007-03-14 | 2012-06-27 | Нопп Ньюросайенсиз, Инк. | Синтез хирально очищенных замещенных бензотиазолдиаминов |
CN101429173B (zh) * | 2007-11-09 | 2012-12-05 | 重庆医药工业研究院有限责任公司 | 一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢-苯并噻唑的制备方法 |
WO2010022140A1 (en) | 2008-08-19 | 2010-02-25 | Knopp Neurosciences, Inc. | Compositions and methods of using (r)-pramipexole |
WO2011021214A2 (en) * | 2009-08-07 | 2011-02-24 | Msn Laboratories Limited | Improved process for the preparation of (s)-2-amino-4,5,6,7-tetrahydro-6 - (propylamino) benzothiazole and its pharmaceutically acceptable salts |
WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
CA2918035C (en) | 2013-07-12 | 2023-01-03 | Knopp Biosciences Llc | Use of dexpramipexole in the treatment of disorders associated with elevated levels of eosinophils and/or basophils |
US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
PT3033081T (pt) | 2013-08-13 | 2021-06-01 | Knopp Biosciences Llc | Composições e métodos para o tratamento da urticária crónica |
AU2014306683B2 (en) | 2013-08-13 | 2017-10-12 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
CN104311507A (zh) * | 2013-10-09 | 2015-01-28 | 安徽万邦医药科技有限公司 | (6s)-2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法 |
CN103613562B (zh) * | 2013-11-25 | 2015-09-30 | 浙江美诺华药物化学有限公司 | 一种普拉克索的制备方法 |
CN107573301B (zh) * | 2017-11-08 | 2020-08-11 | 江苏长青农化股份有限公司 | 一种三环唑中间体的制备方法 |
CN109232471B (zh) * | 2018-10-31 | 2022-05-10 | 安徽省庆云医药股份有限公司 | 一种盐酸普拉克索的制备方法 |
CN111362884A (zh) * | 2018-12-26 | 2020-07-03 | 江苏神龙药业股份有限公司 | 一种2,6-二氨基-4,5,6,7-四氢-苯并噻唑的工业化制备方法 |
CN110734413A (zh) * | 2019-12-02 | 2020-01-31 | 山东铂源药业有限公司 | 一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3447075A1 (de) * | 1984-12-22 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel |
ATE45735T1 (de) * | 1984-12-22 | 1989-09-15 | Thomae Gmbh Dr K | Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arnzneimittel. |
ES2187249B1 (es) * | 2000-09-18 | 2004-09-16 | Synthon Bv | Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles. |
-
2002
- 2002-11-04 GB GB0225701A patent/GB2394951A/en not_active Withdrawn
-
2003
- 2003-11-03 PT PT03769701T patent/PT1562921E/pt unknown
- 2003-11-03 PL PL376543A patent/PL376543A1/pl not_active IP Right Cessation
- 2003-11-03 WO PCT/GB2003/004734 patent/WO2004041797A1/en active IP Right Grant
- 2003-11-03 MX MXPA05004815A patent/MXPA05004815A/es active IP Right Grant
- 2003-11-03 JP JP2004549326A patent/JP4708792B2/ja not_active Expired - Fee Related
- 2003-11-03 AU AU2003278396A patent/AU2003278396B2/en not_active Ceased
- 2003-11-03 US US10/533,637 patent/US7285669B2/en not_active Expired - Fee Related
- 2003-11-03 RU RU2005117364/04A patent/RU2305097C2/ru not_active IP Right Cessation
- 2003-11-03 BR BR0315919-1A patent/BR0315919A/pt not_active IP Right Cessation
- 2003-11-03 DE DE60321208T patent/DE60321208D1/de not_active Expired - Lifetime
- 2003-11-03 EP EP03769701A patent/EP1562921B1/en not_active Expired - Lifetime
- 2003-11-03 CN CNB2003801082013A patent/CN100551918C/zh not_active Expired - Fee Related
- 2003-11-03 AP AP2005003306A patent/AP1882A/xx active
- 2003-11-03 KR KR1020057007963A patent/KR101086844B1/ko not_active IP Right Cessation
- 2003-11-03 AT AT03769701T patent/ATE396180T1/de not_active IP Right Cessation
- 2003-11-03 ZA ZA200503548A patent/ZA200503548B/en unknown
- 2003-11-03 CA CA2505179A patent/CA2505179C/en not_active Expired - Fee Related
- 2003-11-03 NZ NZ539953A patent/NZ539953A/en not_active IP Right Cessation
-
2005
- 2005-05-04 TN TNP2005000125A patent/TNSN05125A1/en unknown
- 2005-05-04 NO NO20052189A patent/NO20052189L/no unknown
- 2005-05-05 HR HR20050403A patent/HRPK20050403B3/xx not_active IP Right Cessation
- 2005-06-02 IS IS7882A patent/IS7882A/is unknown
- 2005-06-02 MA MA28311A patent/MA27534A1/fr unknown
- 2005-06-03 EC EC2005005835A patent/ECSP055835A/es unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
VOID | Decisions declaring the decisions on the grant of the patent lapsed |