IS3718A7 - Amínóbenzodiazepines og aðferð til framleiðslu þess - Google Patents

Amínóbenzodiazepines og aðferð til framleiðslu þess

Info

Publication number
IS3718A7
IS3718A7 IS3718A IS3718A IS3718A7 IS 3718 A7 IS3718 A7 IS 3718A7 IS 3718 A IS3718 A IS 3718A IS 3718 A IS3718 A IS 3718A IS 3718 A7 IS3718 A7 IS 3718A7
Authority
IS
Iceland
Prior art keywords
aminobenzodiazepines
production
Prior art date
Application number
IS3718A
Other languages
English (en)
Inventor
Roberte Bellemin Anne
Valentine Earley James
Hsu Ming-Chu
Yik-Kai Tam Steve
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of IS3718A7 publication Critical patent/IS3718A7/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
IS3718A 1990-06-18 1991-06-14 Amínóbenzodiazepines og aðferð til framleiðslu þess IS3718A7 (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,500 US5141735A (en) 1990-06-18 1990-06-18 Substituted amino-benzodiazepines having anitviral activity

Publications (1)

Publication Number Publication Date
IS3718A7 true IS3718A7 (is) 1991-12-19

Family

ID=24151485

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3718A IS3718A7 (is) 1990-06-18 1991-06-14 Amínóbenzodiazepines og aðferð til framleiðslu þess

Country Status (21)

Country Link
US (1) US5141735A (is)
EP (1) EP0462522A1 (is)
JP (1) JPH04230280A (is)
KR (1) KR920000746A (is)
CN (1) CN1057462A (is)
AU (1) AU7846991A (is)
BR (1) BR9102489A (is)
CA (1) CA2044694A1 (is)
CS (1) CS182991A3 (is)
FI (1) FI912927A (is)
HU (1) HUT58069A (is)
IE (1) IE912061A1 (is)
IL (1) IL98499A0 (is)
IS (1) IS3718A7 (is)
LT (1) LTIP863A (is)
MC (1) MC2263A1 (is)
MX (1) MX26267A (is)
NO (1) NO912346L (is)
NZ (1) NZ238552A (is)
PT (1) PT98007A (is)
ZA (1) ZA914202B (is)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69333270T2 (de) 1992-03-11 2004-08-05 Narhex Ltd. Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
RU2126794C1 (ru) * 1992-03-11 1999-02-27 Нархекс Лимитед Аминопроизводные оксо- или гидроксизамещенных гидразинов, способ их получения и фармацевтические композиции для ингибирования ретровирусной протеазы
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
SI9300288A (sl) * 1992-06-16 1993-12-31 Hoffmann La Roche Benzodiazepini
JPH08502966A (ja) * 1992-10-23 1996-04-02 ユニバーシティー・オブ・マサチューセッツ・メディカル・センター Ｒｎａ／リガンド結合の低分子抑制
US5939430A (en) * 1993-02-22 1999-08-17 Merrell Pharmaceuticals Inc. Combinations of retroviral inhibitors
US5578573A (en) * 1995-01-20 1996-11-26 Houghten Pharmaceuticals, Inc. Viral integrase inhibiting peptides
WO1998016111A1 (en) * 1996-10-16 1998-04-23 Shaman Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer antidiarrheal compositions
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
GB0015904D0 (en) 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
US20020150541A1 (en) * 2000-09-12 2002-10-17 Gene Trol Biotherapeutics, Inc. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
EP1318834A2 (en) * 2000-09-12 2003-06-18 Genetrol Biotherapeutics, Inc. Compositions comprising mixtures of human cytokines and methods of producing the same
US20030129162A1 (en) * 2000-09-12 2003-07-10 Lau Allan S. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
JP2005089298A (ja) * 2001-09-18 2005-04-07 Japan Tobacco Inc ナフタレン化合物及びその医薬用途
BR0213093A (pt) * 2001-10-05 2005-03-15 Intermune Inc Métodos para tratamento de fibrose hepática e de infecção pelo vìrus da hepatite c
EP1691852A2 (en) * 2003-11-10 2006-08-23 Angiotech International AG Medical implants and fibrosis-inducing agents
KR100652975B1 (ko) * 2005-03-17 2006-12-01 유해일 옥수숫대 반화학 기계펄프의 제조방법
EP2685985B1 (en) 2011-03-17 2016-08-31 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Methods for treating leukemia and disorders mediated by cbf and runx1 proteins
EP3535253A1 (en) * 2016-11-01 2019-09-11 H. Hoffnabb-La Roche Ag 1,3-dihydro-1,4-benzodiazepine-2-thiones for the treatment of cns related diseases
US11229662B2 (en) 2016-11-15 2022-01-25 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
CA3082643A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition
WO2019099595A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. NANO-EMULSION OF CBFβ-RUNX1 INHIBITOR FOR OCULAR DRUG DELIVERY

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3267110A (en) * 1960-06-03 1966-08-16 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketones
NL122319C (is) * 1961-06-20
NL295083A (is) * 1962-07-10
US3330481A (en) * 1965-03-18 1967-07-11 Filtra Inc Dispersant dispenser of an absorbent or adsorbent material
CH502354A (de) * 1967-03-08 1971-01-31 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
ZA698792B (en) * 1968-12-30 1971-03-31 Fujisawa Pharmaceutical Co Novel antibiotic and derivatives and production thereof
JPS4843755B1 (is) * 1969-06-26 1973-12-20
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives
US3954728A (en) * 1972-07-13 1976-05-04 Hoffman-La Roche Inc. Preparation of triazolo benzodiazepines and novel compounds
DE3619202A1 (de) * 1986-06-07 1987-12-10 Merz & Co Gmbh & Co Verwendung von avaron und avarol sowie von derivaten davon zur bekaempfung von aids und arc
US4788181A (en) * 1986-09-29 1988-11-29 The United States Of America As Represented By The Department Of Health And Human Services 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Also Published As

Publication number Publication date
CS182991A3 (en) 1992-04-15
EP0462522A1 (en) 1991-12-27
ZA914202B (en) 1992-03-25
BR9102489A (pt) 1992-01-21
IE912061A1 (en) 1991-12-18
US5141735A (en) 1992-08-25
NO912346L (no) 1991-12-19
PT98007A (pt) 1992-03-31
AU7846991A (en) 1992-01-02
HUT58069A (en) 1992-01-28
NZ238552A (en) 1993-08-26
LTIP863A (en) 1995-03-27
FI912927A0 (fi) 1991-06-17
CN1057462A (zh) 1992-01-01
JPH04230280A (ja) 1992-08-19
IL98499A0 (en) 1992-07-15
KR920000746A (ko) 1992-01-29
CA2044694A1 (en) 1991-12-19
FI912927A (fi) 1991-12-19
MX26267A (es) 1993-09-01
MC2263A1 (fr) 1993-04-26
HU912005D0 (en) 1991-12-30
NO912346D0 (no) 1991-06-17

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