IS3555A7 - Pyrrol-afleiður og aðferð til framleiðslu þeirra - Google Patents

Pyrrol-afleiður og aðferð til framleiðslu þeirra

Info

Publication number
IS3555A7
IS3555A7 IS3555A IS3555A IS3555A7 IS 3555 A7 IS3555 A7 IS 3555A7 IS 3555 A IS3555 A IS 3555A IS 3555 A IS3555 A IS 3555A IS 3555 A7 IS3555 A7 IS 3555A7
Authority
IS
Iceland
Prior art keywords
pyrrol derivatives
pyrrol
derivatives
Prior art date
Application number
IS3555A
Other languages
English (en)
Inventor
D. Davis Peter
H. Hill Christopher
Lawton Geoffrey
Original Assignee
F. Hoffman-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffman-La Roche Ag filed Critical F. Hoffman-La Roche Ag
Publication of IS3555A7 publication Critical patent/IS3555A7/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
IS3555A 1989-02-23 1990-02-22 Pyrrol-afleiður og aðferð til framleiðslu þeirra IS3555A7 (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898904161A GB8904161D0 (en) 1989-02-23 1989-02-23 Substituted pyrroles

Publications (1)

Publication Number Publication Date
IS3555A7 true IS3555A7 (is) 1990-08-24

Family

ID=10652205

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3555A IS3555A7 (is) 1989-02-23 1990-02-22 Pyrrol-afleiður og aðferð til framleiðslu þeirra

Country Status (8)

Country Link
US (1) US5721245A (is)
KR (1) KR0173450B1 (is)
GB (2) GB8904161D0 (is)
ID (1) ID996B (is)
IS (1) IS3555A7 (is)
MX (1) MX19501A (is)
YU (1) YU47831B (is)
ZA (1) ZA901209B (is)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1185229C (zh) 2000-07-27 2005-01-19 霍夫曼-拉罗奇有限公司 用作糖原合酶激酶－3β抑制剂的3－吲哚基－4－苯基－1H－吡咯－2,5－二酮衍生物
US6645970B2 (en) * 2000-11-07 2003-11-11 Novartis Ag Indolylmaleimide derivatives
BR0116468A (pt) * 2000-12-08 2004-06-29 Ortho Mcneil Pharm Inc Compostos de pirrolina substituìda por indazolila como inibidores de cinase
DK1483265T3 (da) 2002-03-05 2007-03-19 Lilly Co Eli Purinderivater som kinaseinhibitorer
CN1639152A (zh) * 2002-03-08 2005-07-13 伊莱利利公司 吡咯－2,5－二酮衍生物及其作为gsk－3抑制剂的用途
AU2003240517A1 (en) * 2002-06-05 2003-12-22 Janssen Pharmaceutica N.V. Substituted pyrrolines as kinase inhibitors
BR0311821A (pt) 2002-06-05 2005-04-05 Janssen Pharmaceutica Nv Derivados de bisindolil-maleimid como inibidores de cinase
CA2393720C (en) * 2002-07-12 2010-09-14 Eli Lilly And Company Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride
CN1832940A (zh) * 2003-06-13 2006-09-13 詹森药业有限公司 用作激酶抑制剂的取代的吲唑基(吲哚基)马来酰亚胺衍生物
EP2289892B1 (en) * 2005-02-09 2012-08-22 ArQule, Inc. Maleimide derivatives, pharmaceutical compositions amd methods for treatment of cancer
CA2673368C (en) * 2006-12-19 2014-10-28 The Board Of Trustees Of The University Of Illinois 3-benzofuranyl-4-indolyl maleimides as potent gsk3 inhibitors for neurogenerative disorders
WO2009002806A1 (en) * 2007-06-22 2008-12-31 Arqule, Inc. Pyrrolidinone, pyrrolidine-2, 5-dione, pyrrolidine and thiosuccinimide derivatives, compositions and methods for treatment of cancer
WO2009002808A2 (en) * 2007-06-22 2008-12-31 Arqule, Inc. Quinazolinone compounds and methods of use thereof
CA2912546A1 (en) * 2007-06-22 2008-12-31 Arqule, Inc. Compositions and methods for treatment of cancer
TWI428132B (zh) 2007-07-02 2014-03-01 Lilly Co Eli 癌症化療效果之強化
EP2343291A1 (en) 2009-12-18 2011-07-13 Johannes Gutenberg-Universität Mainz 3-(Indolyl)- or 3-(Azaindolyl)-4-arylmaleimide compounds and their use in tumor treatment
EP2474541A1 (en) 2010-12-23 2012-07-11 Johannes- Gutenberg-Universität Mainz Conjugated 3-(indolyl)- and 3-(azaindolyl)-4-arylmaleimide compounds and their use in tumor treatment
AU2014257578B2 (en) * 2013-04-23 2017-11-16 Laboratorios Del Dr. Esteve, S.A. Pyrazino[1,2-a]indole compounds, their preparation and use in medicaments
EP3187495A1 (en) 2015-12-30 2017-07-05 Johannes Gutenberg-Universität Mainz 3-(5-fluoroindolyl)-4-arylmaleimide compounds and their use in tumor treatment
KR20190104359A (ko) * 2016-12-30 2019-09-09 프리퀀시 테라퓨틱스, 인크. 줄기/전구체 지지 세포의 자가 재생을 유도하기 위한 1h-피롤-2,5-다이온 화합물 및 이의 사용 방법
JP2022520671A (ja) 2019-02-08 2022-03-31 フリークエンシー・セラピューティクス・インコーポレイテッド 耳障害を治療するためのバルプロ酸化合物及びｗｎｔ作動薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317524A (en) * 1965-02-04 1967-05-02 American Home Prod Substituted 1, 2, 3, 4-tetrahydro-pyrazino[1, 2-a]indoles
JPS5373501A (en) * 1976-12-11 1978-06-30 Kitasato Inst Novel antibiotics amm2282 and process for preparing same
SK278989B6 (sk) * 1988-02-10 1998-05-06 F. Hoffmann-La Roche Ag Substituované pyroly, ich použitie na výrobu lieči

Also Published As

Publication number Publication date
ZA901209B (en) 1991-02-27
YU47831B (sr) 1996-01-09
KR910015566A (ko) 1991-09-30
KR0173450B1 (ko) 1999-02-01
US5721245A (en) 1998-02-24
GB8904161D0 (en) 1989-04-05
YU26590A (en) 1991-08-31
GB8928210D0 (en) 1990-02-14
ID996B (id) 1996-10-08
MX19501A (es) 1993-10-01

Similar Documents

Publication Publication Date Title
IS3555A7 (is) Pyrrol-afleiður og aðferð til framleiðslu þeirra
IS3433A7 (is) Efni afleidd af pyrról og aðferð til framleiðslu þeirra
DK194589A (da) Partikelformede vaskemidler og fremgangsmaade til fremstilling deraf
NO940825D0 (no) 2-Debenzoyl-2-acyltaxolderivater og fremgangsmåter ved fremstilling derav
NO175204C (no) Imidoperoksikarboksylsyrer, fremgangsmåte for deres fremstilling og anvendelse
CY2005005I2 (el) Pyrrolidine derivatives
IS3718A7 (is) Amínóbenzodiazepines og aðferð til framleiðslu þess
DK0635004T3 (da) 4-Diphenylmethylpiperidinderivater og fremgangsmåde til fremstilling deraf
DK417885A (da) Fremgangsmaade til forkromning og derved fremstillet genstand
DK0380248T4 (da) Modificeret polydextrose og fremgangsmåde til fremstilling deraf
DK617487D0 (da) Pyrrolderivater og deoxyanaloge deraf
DK96394A (da) 5-Halogenalkylidinimono-1-arylpyrazoler og fremgangsmåde til fremstilling deraf
DK69989D0 (da) Benzodioxolderivater og fremgangsmaade til fremstilling deraf
DK0415641T3 (da) Substituerede glutaramidsyrer og derivater
DK1693A (da) Pyranobenzoxadiazolderivat og fremgangsmaade til fremstilling deraf
DE68913672T2 (de) N-substituierte Maleimid-Herstellungsverfahren.
IS3725A7 (is) Amínósýruafleiður og aðferð til framleiðslu þeirra
IS3611A7 (is) Aromatísk karboxýl amíð og aðferð til framleiðsluþeirra
DK0425001T3 (da) Naturlige delta-lactoner og fremgangsmåde til fremstilling deraf
DK0381661T3 (da) 1-E3-(2-Hydroxy-3-alkylaminopropoxy)-2-theinyl)-3-phenyl-1-propanoner og fremgangsmåde til fremstilling deraf
DK487688A (da) Benzofuranderivater og fremgangsmaade til fremstilling deraf
TR24796A (tr) Tetratiokarbonat islemi
DK624588D0 (da) 4-demethoxy-anthracyclin-derivater og fremgangsmaade til fremstilling deraf
IS3588A7 (is) Amínóalkylbensól-afleiður og aðferð til framleiðslu þeirra
IS3610A7 (is) Amínóalkoxybensól afleiður og aðferð til framleiðslu þeirra