BR9102489A - Aminobenzo diazepinas,benzodiaze pinotionas,processo para preparar um composto,medicamento,uso e composto - Google Patents

Aminobenzo diazepinas,benzodiaze pinotionas,processo para preparar um composto,medicamento,uso e composto

Info

Publication number
BR9102489A
BR9102489A BR919102489A BR9102489A BR9102489A BR 9102489 A BR9102489 A BR 9102489A BR 919102489 A BR919102489 A BR 919102489A BR 9102489 A BR9102489 A BR 9102489A BR 9102489 A BR9102489 A BR 9102489A
Authority
BR
Brazil
Prior art keywords
compound
pinotionas
benzodiaze
diazepines
aminobenzo
Prior art date
Application number
BR919102489A
Other languages
English (en)
Inventor
Anne Roberte Bellemin
James Valentine Earley
Ming-Chu Hsu
Steve Yik-Kai Tam
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR9102489A publication Critical patent/BR9102489A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR919102489A 1990-06-18 1991-06-17 Aminobenzo diazepinas,benzodiaze pinotionas,processo para preparar um composto,medicamento,uso e composto BR9102489A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,500 US5141735A (en) 1990-06-18 1990-06-18 Substituted amino-benzodiazepines having anitviral activity

Publications (1)

Publication Number Publication Date
BR9102489A true BR9102489A (pt) 1992-01-21

Family

ID=24151485

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919102489A BR9102489A (pt) 1990-06-18 1991-06-17 Aminobenzo diazepinas,benzodiaze pinotionas,processo para preparar um composto,medicamento,uso e composto

Country Status (21)

Country Link
US (1) US5141735A (pt)
EP (1) EP0462522A1 (pt)
JP (1) JPH04230280A (pt)
KR (1) KR920000746A (pt)
CN (1) CN1057462A (pt)
AU (1) AU7846991A (pt)
BR (1) BR9102489A (pt)
CA (1) CA2044694A1 (pt)
CS (1) CS182991A3 (pt)
FI (1) FI912927A (pt)
HU (1) HUT58069A (pt)
IE (1) IE912061A1 (pt)
IL (1) IL98499A0 (pt)
IS (1) IS3718A7 (pt)
LT (1) LTIP863A (pt)
MC (1) MC2263A1 (pt)
MX (1) MX26267A (pt)
NO (1) NO912346L (pt)
NZ (1) NZ238552A (pt)
PT (1) PT98007A (pt)
ZA (1) ZA914202B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA93002392A (es) 1992-03-11 2005-02-04 Narhex Ltd Derivados amino de hidrocarburos-oxo e hidroxi-substituidos.
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
SI9300288A (sl) * 1992-06-16 1993-12-31 Hoffmann La Roche Benzodiazepini
EP0668766A1 (en) * 1992-10-23 1995-08-30 University Of Massachusetts Medical Center Small molecule inhibition of rna/ligand binding
US5939430A (en) * 1993-02-22 1999-08-17 Merrell Pharmaceuticals Inc. Combinations of retroviral inhibitors
US5578573A (en) * 1995-01-20 1996-11-26 Houghten Pharmaceuticals, Inc. Viral integrase inhibiting peptides
CA2269078C (en) * 1996-10-16 2012-01-24 Shaman Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer antidiarrheal compositions
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
GB0015904D0 (en) 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
JP2004529851A (ja) * 2000-09-12 2004-09-30 ジーントロール バイオセラピューティクス, インコーポレイテッド ヒトサイトカインの混合物を含む組成物およびその産生方法
US20020150541A1 (en) * 2000-09-12 2002-10-17 Gene Trol Biotherapeutics, Inc. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
US20030129162A1 (en) * 2000-09-12 2003-07-10 Lau Allan S. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
JP2005089298A (ja) * 2001-09-18 2005-04-07 Japan Tobacco Inc ナフタレン化合物及びその医薬用途
CA2460341A1 (en) * 2001-10-05 2003-04-17 Intermune, Inc. Methods of treating liver fibrosis and hepatitis c virus infection
CA2536041A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
KR100652975B1 (ko) * 2005-03-17 2006-12-01 유해일 옥수숫대 반화학 기계펄프의 제조방법
WO2012125787A1 (en) 2011-03-17 2012-09-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic METHODS FOR TREATING LEUKEMIA AND DISORDERS MEDIATED BY CBFβ AND RUNX1 PROTEINS
EP3535253A1 (en) * 2016-11-01 2019-09-11 H. Hoffnabb-La Roche Ag 1,3-dihydro-1,4-benzodiazepine-2-thiones for the treatment of cns related diseases
US11229662B2 (en) 2016-11-15 2022-01-25 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
US11583497B2 (en) 2017-11-14 2023-02-21 The Schepens Eye Research Institute, Inc. Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery
US11739326B2 (en) 2017-11-14 2023-08-29 Massachusetts Eye And Ear Infirmary RUNX1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3267110A (en) * 1960-06-03 1966-08-16 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketones
NL131733C (pt) * 1961-06-20
NL126389C (pt) * 1962-07-10
US3330481A (en) * 1965-03-18 1967-07-11 Filtra Inc Dispersant dispenser of an absorbent or adsorbent material
CH502354A (de) * 1967-03-08 1971-01-31 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
JPS4843755B1 (pt) * 1969-06-26 1973-12-20
ZA698792B (en) * 1968-12-30 1971-03-31 Fujisawa Pharmaceutical Co Novel antibiotic and derivatives and production thereof
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives
US3954728A (en) * 1972-07-13 1976-05-04 Hoffman-La Roche Inc. Preparation of triazolo benzodiazepines and novel compounds
DE3619202A1 (de) * 1986-06-07 1987-12-10 Merz & Co Gmbh & Co Verwendung von avaron und avarol sowie von derivaten davon zur bekaempfung von aids und arc
US4788181A (en) * 1986-09-29 1988-11-29 The United States Of America As Represented By The Department Of Health And Human Services 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Also Published As

Publication number Publication date
IS3718A7 (is) 1991-12-19
FI912927A (fi) 1991-12-19
KR920000746A (ko) 1992-01-29
CS182991A3 (en) 1992-04-15
IL98499A0 (en) 1992-07-15
CA2044694A1 (en) 1991-12-19
MC2263A1 (fr) 1993-04-26
US5141735A (en) 1992-08-25
FI912927A0 (fi) 1991-06-17
AU7846991A (en) 1992-01-02
JPH04230280A (ja) 1992-08-19
IE912061A1 (en) 1991-12-18
ZA914202B (en) 1992-03-25
CN1057462A (zh) 1992-01-01
HUT58069A (en) 1992-01-28
LTIP863A (en) 1995-03-27
NO912346D0 (no) 1991-06-17
HU912005D0 (en) 1991-12-30
NZ238552A (en) 1993-08-26
EP0462522A1 (en) 1991-12-27
MX26267A (es) 1993-09-01
PT98007A (pt) 1992-03-31
NO912346L (no) 1991-12-19

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Legal Events

Date Code Title Description
KF Request for proof of payment of annual fee
FD5 Application fees: dismissal - article 86 of industrial property law