LTIP863A - Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases - Google Patents

Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases

Info

Publication number
LTIP863A
LTIP863A LTIP863A LTIP863A LTIP863A LT IP863 A LTIP863 A LT IP863A LT IP863 A LTIP863 A LT IP863A LT IP863 A LTIP863 A LT IP863A LT IP863 A LTIP863 A LT IP863A
Authority
LT
Lithuania
Prior art keywords
aminobenzodiazepines
prevention
preparing
treatment
application
Prior art date
Application number
LTIP863A
Inventor
Anne Roberte Bellemin
James Valentine Earley
Ming-Chu Hsu
Steve Yik-Kai Tam
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of LTIP863A publication Critical patent/LTIP863A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
LTIP863A 1990-06-18 1993-08-16 Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases LTIP863A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,500 US5141735A (en) 1990-06-18 1990-06-18 Substituted amino-benzodiazepines having anitviral activity

Publications (1)

Publication Number Publication Date
LTIP863A true LTIP863A (en) 1995-03-27

Family

ID=24151485

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP863A LTIP863A (en) 1990-06-18 1993-08-16 Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases

Country Status (21)

Country Link
US (1) US5141735A (en)
EP (1) EP0462522A1 (en)
JP (1) JPH04230280A (en)
KR (1) KR920000746A (en)
CN (1) CN1057462A (en)
AU (1) AU7846991A (en)
BR (1) BR9102489A (en)
CA (1) CA2044694A1 (en)
CS (1) CS182991A3 (en)
FI (1) FI912927A (en)
HU (1) HUT58069A (en)
IE (1) IE912061A1 (en)
IL (1) IL98499A0 (en)
IS (1) IS3718A7 (en)
LT (1) LTIP863A (en)
MC (1) MC2263A1 (en)
MX (1) MX26267A (en)
NO (1) NO912346L (en)
NZ (1) NZ238552A (en)
PT (1) PT98007A (en)
ZA (1) ZA914202B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69333270T2 (en) 1992-03-11 2004-08-05 Narhex Ltd. AMINE DERIVATIVES OF OXO AND HYDROXY SUBSTITUTED CARBON HYDROGEN
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
SI9300288A (en) * 1992-06-16 1993-12-31 Hoffmann La Roche Benzodiazepine derivatives
WO1994009792A1 (en) * 1992-10-23 1994-05-11 University Of Massachusetts Medical Center Small molecule inhibition of rna/ligand binding
US5939430A (en) * 1993-02-22 1999-08-17 Merrell Pharmaceuticals Inc. Combinations of retroviral inhibitors
US5578573A (en) * 1995-01-20 1996-11-26 Houghten Pharmaceuticals, Inc. Viral integrase inhibiting peptides
KR100467532B1 (en) * 1996-10-16 2005-01-24 피에스 팔마큐티칼스 인코퍼레이션 Enteric Formulation of Proanthocyanidin Polymer Anti-diarrheal Compositions
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
GB0015904D0 (en) * 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
US20020150541A1 (en) * 2000-09-12 2002-10-17 Gene Trol Biotherapeutics, Inc. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
JP2004529851A (en) * 2000-09-12 2004-09-30 ジーントロール バイオセラピューティクス， インコーポレイテッド Composition containing a mixture of human cytokines and method for producing the same
US20030129162A1 (en) * 2000-09-12 2003-07-10 Lau Allan S. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
JP2005089298A (en) * 2001-09-18 2005-04-07 Japan Tobacco Inc Naphthalene compound and its pharmaceutical use
PL371683A1 (en) * 2001-10-05 2005-06-27 Intermune, Inc. Methods of treating liver fibrosis and hepatitis c virus infection
WO2005046746A2 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
KR100652975B1 (en) * 2005-03-17 2006-12-01 유해일 Manufacturing method of semichemical mechanical pulp from cornstalk
WO2012125787A1 (en) 2011-03-17 2012-09-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic METHODS FOR TREATING LEUKEMIA AND DISORDERS MEDIATED BY CBFβ AND RUNX1 PROTEINS
JP7139323B2 (en) * 2016-11-01 2022-09-20 エフ．ホフマン－ラ ロシュ アーゲー 1,3-dihydro-1,4-benzodiazepine-2-thiones for treating CNS-related diseases
WO2018093797A1 (en) 2016-11-15 2018-05-24 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
WO2019099595A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. NANO-EMULSION OF CBFβ-RUNX1 INHIBITOR FOR OCULAR DRUG DELIVERY
CA3082643A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3267110A (en) * 1960-06-03 1966-08-16 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketones
NL279830A (en) * 1961-06-20
NL126389C (en) * 1962-07-10
US3330481A (en) * 1965-03-18 1967-07-11 Filtra Inc Dispersant dispenser of an absorbent or adsorbent material
CH502354A (en) * 1967-03-08 1971-01-31 Hoffmann La Roche 2-amino-1 4-benzodiazepines
JPS4843755B1 (en) * 1969-06-26 1973-12-20
ZA698792B (en) * 1968-12-30 1971-03-31 Fujisawa Pharmaceutical Co Novel antibiotic and derivatives and production thereof
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives
US3954728A (en) * 1972-07-13 1976-05-04 Hoffman-La Roche Inc. Preparation of triazolo benzodiazepines and novel compounds
DE3619202A1 (en) * 1986-06-07 1987-12-10 Merz & Co Gmbh & Co USE OF AVARON AND AVAROL AND DERIVATIVES THEREOF TO COMBAT AIDS AND ARC
US4788181A (en) * 1986-09-29 1988-11-29 The United States Of America As Represented By The Department Of Health And Human Services 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Also Published As

Publication number Publication date
CS182991A3 (en) 1992-04-15
HUT58069A (en) 1992-01-28
ZA914202B (en) 1992-03-25
US5141735A (en) 1992-08-25
MC2263A1 (en) 1993-04-26
KR920000746A (en) 1992-01-29
FI912927A (en) 1991-12-19
NZ238552A (en) 1993-08-26
IS3718A7 (en) 1991-12-19
PT98007A (en) 1992-03-31
EP0462522A1 (en) 1991-12-27
CA2044694A1 (en) 1991-12-19
NO912346L (en) 1991-12-19
NO912346D0 (en) 1991-06-17
CN1057462A (en) 1992-01-01
IL98499A0 (en) 1992-07-15
FI912927A0 (en) 1991-06-17
BR9102489A (en) 1992-01-21
AU7846991A (en) 1992-01-02
JPH04230280A (en) 1992-08-19
IE912061A1 (en) 1991-12-18
MX26267A (en) 1993-09-01
HU912005D0 (en) 1991-12-30

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Legal Events

Date Code Title Description
FD9A Withdrawn applications

Free format text: 950803