LTIP863A - Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases - Google Patents

Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases

Info

Publication number
LTIP863A
LTIP863A LTIP863A LTIP863A LTIP863A LT IP863 A LTIP863 A LT IP863A LT IP863 A LTIP863 A LT IP863A LT IP863 A LTIP863 A LT IP863A LT IP863 A LTIP863 A LT IP863A
Authority
LT
Lithuania
Prior art keywords
aminobenzodiazepines
prevention
preparing
treatment
application
Prior art date
Application number
LTIP863A
Other languages
English (en)
Inventor
Anne Roberte Bellemin
James Valentine Earley
Ming-Chu Hsu
Steve Yik-Kai Tam
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of LTIP863A publication Critical patent/LTIP863A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTIP863A 1990-06-18 1993-08-16 Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases LTIP863A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,500 US5141735A (en) 1990-06-18 1990-06-18 Substituted amino-benzodiazepines having anitviral activity

Publications (1)

Publication Number Publication Date
LTIP863A true LTIP863A (en) 1995-03-27

Family

ID=24151485

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP863A LTIP863A (en) 1990-06-18 1993-08-16 Aminobenzodiazepines, process for preparing thereof and application for the treatment and prevention of viral diseases

Country Status (21)

Country Link
US (1) US5141735A (xx)
EP (1) EP0462522A1 (xx)
JP (1) JPH04230280A (xx)
KR (1) KR920000746A (xx)
CN (1) CN1057462A (xx)
AU (1) AU7846991A (xx)
BR (1) BR9102489A (xx)
CA (1) CA2044694A1 (xx)
CS (1) CS182991A3 (xx)
FI (1) FI912927A (xx)
HU (1) HUT58069A (xx)
IE (1) IE912061A1 (xx)
IL (1) IL98499A0 (xx)
IS (1) IS3718A7 (xx)
LT (1) LTIP863A (xx)
MC (1) MC2263A1 (xx)
MX (1) MX26267A (xx)
NO (1) NO912346L (xx)
NZ (1) NZ238552A (xx)
PT (1) PT98007A (xx)
ZA (1) ZA914202B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
RU2126794C1 (ru) * 1992-03-11 1999-02-27 Нархекс Лимитед Аминопроизводные оксо- или гидроксизамещенных гидразинов, способ их получения и фармацевтические композиции для ингибирования ретровирусной протеазы
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
ATE253050T1 (de) 1992-03-11 2003-11-15 Narhex Ltd Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
SI9300288A (sl) * 1992-06-16 1993-12-31 Hoffmann La Roche Benzodiazepini
WO1994009792A1 (en) * 1992-10-23 1994-05-11 University Of Massachusetts Medical Center Small molecule inhibition of rna/ligand binding
US5939430A (en) * 1993-02-22 1999-08-17 Merrell Pharmaceuticals Inc. Combinations of retroviral inhibitors
US5578573A (en) * 1995-01-20 1996-11-26 Houghten Pharmaceuticals, Inc. Viral integrase inhibiting peptides
DK0935417T3 (da) * 1996-10-16 2009-08-10 Napo Pharmaceuticals Inc Enteroformuleringer af proanthocyanidin-polymer-sammensætninger mod diarré
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
GB0015904D0 (en) 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
CA2422060A1 (en) * 2000-09-12 2002-03-21 Genetrol Biotherapeutics, Inc. Compositions comprising mixtures of human cytokines and methods of producing the same
US20030129162A1 (en) * 2000-09-12 2003-07-10 Lau Allan S. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
US20020150541A1 (en) * 2000-09-12 2002-10-17 Gene Trol Biotherapeutics, Inc. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
JP2005089298A (ja) * 2001-09-18 2005-04-07 Japan Tobacco Inc ナフタレン化合物及びその医薬用途
US20050013801A1 (en) * 2001-10-05 2005-01-20 Hsu Henry H. Methods of treating liver fibrosis and hepatitis c virus infection
CA2536041A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
KR100652975B1 (ko) * 2005-03-17 2006-12-01 유해일 옥수숫대 반화학 기계펄프의 제조방법
EP2685985B1 (en) 2011-03-17 2016-08-31 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Methods for treating leukemia and disorders mediated by cbf and runx1 proteins
WO2018083051A1 (en) * 2016-11-01 2018-05-11 F. Hoffmann-La Roche Ag 1,3-dihydro-1,4-benzodiazepine-2-thiones for the treatment of cns related diseases
US11229662B2 (en) 2016-11-15 2022-01-25 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
WO2019099595A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. NANO-EMULSION OF CBFβ-RUNX1 INHIBITOR FOR OCULAR DRUG DELIVERY
CA3082643A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3267110A (en) * 1960-06-03 1966-08-16 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketones
NL122319C (xx) * 1961-06-20
BE634438A (xx) * 1962-07-10
US3330481A (en) * 1965-03-18 1967-07-11 Filtra Inc Dispersant dispenser of an absorbent or adsorbent material
CH502354A (de) * 1967-03-08 1971-01-31 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
ZA698792B (en) * 1968-12-30 1971-03-31 Fujisawa Pharmaceutical Co Novel antibiotic and derivatives and production thereof
JPS4843755B1 (xx) * 1969-06-26 1973-12-20
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives
US3954728A (en) * 1972-07-13 1976-05-04 Hoffman-La Roche Inc. Preparation of triazolo benzodiazepines and novel compounds
DE3619202A1 (de) * 1986-06-07 1987-12-10 Merz & Co Gmbh & Co Verwendung von avaron und avarol sowie von derivaten davon zur bekaempfung von aids und arc
US4788181A (en) * 1986-09-29 1988-11-29 The United States Of America As Represented By The Department Of Health And Human Services 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Also Published As

Publication number Publication date
EP0462522A1 (en) 1991-12-27
KR920000746A (ko) 1992-01-29
NO912346L (no) 1991-12-19
BR9102489A (pt) 1992-01-21
ZA914202B (en) 1992-03-25
IL98499A0 (en) 1992-07-15
NZ238552A (en) 1993-08-26
AU7846991A (en) 1992-01-02
NO912346D0 (no) 1991-06-17
HU912005D0 (en) 1991-12-30
FI912927A (fi) 1991-12-19
CS182991A3 (en) 1992-04-15
CA2044694A1 (en) 1991-12-19
CN1057462A (zh) 1992-01-01
IS3718A7 (is) 1991-12-19
IE912061A1 (en) 1991-12-18
MX26267A (es) 1993-09-01
HUT58069A (en) 1992-01-28
FI912927A0 (fi) 1991-06-17
JPH04230280A (ja) 1992-08-19
US5141735A (en) 1992-08-25
MC2263A1 (fr) 1993-04-26
PT98007A (pt) 1992-03-31

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Legal Events

Date Code Title Description
FD9A Withdrawn applications

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