MC2263A1 - Aminobenzodiazepines et leurs sels pharmaceutiquement acceptables - Google Patents

Aminobenzodiazepines et leurs sels pharmaceutiquement acceptables

Info

Publication number
MC2263A1
MC2263A1 MC912193A MC2193A MC2263A1 MC 2263 A1 MC2263 A1 MC 2263A1 MC 912193 A MC912193 A MC 912193A MC 2193 A MC2193 A MC 2193A MC 2263 A1 MC2263 A1 MC 2263A1
Authority
MC
Monaco
Prior art keywords
aminobenzodiazepines
pharmaceutically acceptable
acceptable salts
salts
pharmaceutically
Prior art date
Application number
MC912193A
Other languages
English (en)
Inventor
Roberte Bellemin Anne
Valentine Earley James
Hsu Ming-Chu
Yik-Kai Tam Steve
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2263A1 publication Critical patent/MC2263A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC912193A 1990-06-18 1991-06-17 Aminobenzodiazepines et leurs sels pharmaceutiquement acceptables MC2263A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,500 US5141735A (en) 1990-06-18 1990-06-18 Substituted amino-benzodiazepines having anitviral activity

Publications (1)

Publication Number Publication Date
MC2263A1 true MC2263A1 (fr) 1993-04-26

Family

ID=24151485

Family Applications (1)

Application Number Title Priority Date Filing Date
MC912193A MC2263A1 (fr) 1990-06-18 1991-06-17 Aminobenzodiazepines et leurs sels pharmaceutiquement acceptables

Country Status (21)

Country Link
US (1) US5141735A (fr)
EP (1) EP0462522A1 (fr)
JP (1) JPH04230280A (fr)
KR (1) KR920000746A (fr)
CN (1) CN1057462A (fr)
AU (1) AU7846991A (fr)
BR (1) BR9102489A (fr)
CA (1) CA2044694A1 (fr)
CS (1) CS182991A3 (fr)
FI (1) FI912927A (fr)
HU (1) HUT58069A (fr)
IE (1) IE912061A1 (fr)
IL (1) IL98499A0 (fr)
IS (1) IS3718A7 (fr)
LT (1) LTIP863A (fr)
MC (1) MC2263A1 (fr)
MX (1) MX26267A (fr)
NO (1) NO912346L (fr)
NZ (1) NZ238552A (fr)
PT (1) PT98007A (fr)
ZA (1) ZA914202B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
EP0633881B1 (fr) * 1992-03-11 2003-10-29 Narhex Limited Derives amines d'hydrocarbures a substitution oxo et hydroxy
ATE253050T1 (de) 1992-03-11 2003-11-15 Narhex Ltd Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
SI9300288A (sl) * 1992-06-16 1993-12-31 Hoffmann La Roche Benzodiazepini
JPH08502966A (ja) * 1992-10-23 1996-04-02 ユニバーシティー・オブ・マサチューセッツ・メディカル・センター Ｒｎａ／リガンド結合の低分子抑制
US5939430A (en) * 1993-02-22 1999-08-17 Merrell Pharmaceuticals Inc. Combinations of retroviral inhibitors
US5578573A (en) * 1995-01-20 1996-11-26 Houghten Pharmaceuticals, Inc. Viral integrase inhibiting peptides
ATE430477T1 (de) * 1996-10-16 2009-05-15 Napo Pharmaceuticals Inc Enteral-formulierungen von proanthocyanidzusammensetzungen gegen diarrhöe
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
GB0015904D0 (en) 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
US20020150552A1 (en) * 2000-09-12 2002-10-17 Lau Allan S. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
US20030129162A1 (en) * 2000-09-12 2003-07-10 Lau Allan S. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
US20020150541A1 (en) * 2000-09-12 2002-10-17 Gene Trol Biotherapeutics, Inc. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
JP2005089298A (ja) * 2001-09-18 2005-04-07 Japan Tobacco Inc ナフタレン化合物及びその医薬用途
KR20050033518A (ko) * 2001-10-05 2005-04-12 인터뮨, 인크. 간섬유증과 ｃ형 간염바이러스 감염의 치료 방법
AU2004289287A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
KR100652975B1 (ko) * 2005-03-17 2006-12-01 유해일 옥수숫대 반화학 기계펄프의 제조방법
EP2685985B1 (fr) 2011-03-17 2016-08-31 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Méthodes de traitement de la leucémie et de troubles à médiation par les protéines cbf et runx1
EP3535253A1 (fr) * 2016-11-01 2019-09-11 H. Hoffnabb-La Roche Ag 1,3-dihydro -1,4-benzodiazépine-2-thiones pour le traitement de maladies liées au snc
WO2018093797A1 (fr) 2016-11-15 2018-05-24 The Schepens Eye Research Institute, Inc. Compositions et méthodes pour le traitement de l'angiogenèse aberrante
JP7416700B2 (ja) 2017-11-14 2024-01-17 ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド 増殖性硝子体網膜症および上皮間葉転換と関連付けられる状態の治療のためのｒｕｎｘ１阻害の方法
WO2019099595A1 (fr) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. NANO-ÉMULSION D'INHIBITEUR DE CBFβ-RUNX1 POUR L'ADMINISTRATION DE MÉDICAMENTS POUR LES YEUX

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3267110A (en) * 1960-06-03 1966-08-16 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketones
NL131733C (fr) * 1961-06-20
NL126389C (fr) * 1962-07-10
US3330481A (en) * 1965-03-18 1967-07-11 Filtra Inc Dispersant dispenser of an absorbent or adsorbent material
CH502354A (de) * 1967-03-08 1971-01-31 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
ZA698792B (en) * 1968-12-30 1971-03-31 Fujisawa Pharmaceutical Co Novel antibiotic and derivatives and production thereof
JPS4843755B1 (fr) * 1969-06-26 1973-12-20
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives
US3954728A (en) * 1972-07-13 1976-05-04 Hoffman-La Roche Inc. Preparation of triazolo benzodiazepines and novel compounds
DE3619202A1 (de) * 1986-06-07 1987-12-10 Merz & Co Gmbh & Co Verwendung von avaron und avarol sowie von derivaten davon zur bekaempfung von aids und arc
US4788181A (en) * 1986-09-29 1988-11-29 The United States Of America As Represented By The Department Of Health And Human Services 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Also Published As

Publication number Publication date
BR9102489A (pt) 1992-01-21
FI912927A0 (fi) 1991-06-17
KR920000746A (ko) 1992-01-29
IE912061A1 (en) 1991-12-18
HUT58069A (en) 1992-01-28
EP0462522A1 (fr) 1991-12-27
CS182991A3 (en) 1992-04-15
HU912005D0 (en) 1991-12-30
PT98007A (pt) 1992-03-31
NO912346D0 (no) 1991-06-17
CN1057462A (zh) 1992-01-01
JPH04230280A (ja) 1992-08-19
NO912346L (no) 1991-12-19
CA2044694A1 (fr) 1991-12-19
US5141735A (en) 1992-08-25
IL98499A0 (en) 1992-07-15
ZA914202B (en) 1992-03-25
NZ238552A (en) 1993-08-26
FI912927A (fi) 1991-12-19
AU7846991A (en) 1992-01-02
MX26267A (es) 1993-09-01
LTIP863A (en) 1995-03-27
IS3718A7 (is) 1991-12-19

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