IN2014KN01030A - - Google Patents

Info

Publication number
IN2014KN01030A
IN2014KN01030A IN1030KON2014A IN2014KN01030A IN 2014KN01030 A IN2014KN01030 A IN 2014KN01030A IN 1030KON2014 A IN1030KON2014 A IN 1030KON2014A IN 2014KN01030 A IN2014KN01030 A IN 2014KN01030A
Authority
IN
India
Prior art keywords
12the
carbamoyl
cyano
denotes
general formula
Prior art date
Application number
Other languages
English (en)
Inventor
Luthra Parven Kumar
Sachin Bhuta
Chandrakant Pise Abhinay
N Chavan Dattatraya
D Metkar Shashikant
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IN2014KN01030A publication Critical patent/IN2014KN01030A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IN1030KON2014 2011-10-21 2012-10-19 IN2014KN01030A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161549800P 2011-10-21 2011-10-21
EP11008484 2011-10-21
PCT/EP2012/004378 WO2013056842A1 (fr) 2011-10-21 2012-10-19 Procédé de préparation de silodosine

Publications (1)

Publication Number Publication Date
IN2014KN01030A true IN2014KN01030A (fr) 2015-10-09

Family

ID=48140363

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1030KON2014 IN2014KN01030A (fr) 2011-10-21 2012-10-19

Country Status (6)

Country Link
US (2) US20150038727A1 (fr)
EP (1) EP2768806B1 (fr)
CN (1) CN104302621A (fr)
ES (1) ES2639196T3 (fr)
IN (1) IN2014KN01030A (fr)
WO (1) WO2013056842A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101447574B1 (ko) * 2013-11-29 2014-10-07 동국제약 주식회사 신규 중간체를 이용한 실로도신의 제조방법
KR102114323B1 (ko) * 2013-12-09 2020-05-22 이니스트에스티 주식회사 광학활성 1-(인돌린-5-일)프로판-2-올 유도체의 제조방법
KR101628946B1 (ko) * 2014-07-09 2016-06-09 동방에프티엘(주) 실로도신의 개선된 제조방법
WO2016189552A2 (fr) * 2015-05-26 2016-12-01 Ipca Laboratories Limited Nouveau procédé de récupération et de recyclage d'énantiomères indésirables de dérivés de 2-aminopropyl-indoline
ES2607639B1 (es) 2015-09-30 2018-02-28 Urquima, S.A Sal de ácido maleico de un intermedio de silodosina
CN106995399A (zh) * 2016-01-25 2017-08-01 北京天泰恒华医药技术有限公司 一种制备赛洛多辛的方法
CN106083689B (zh) * 2016-06-14 2020-07-31 齐鲁制药有限公司 一种赛洛多辛化合物的制备方法
CN106496092B (zh) * 2016-08-30 2019-03-29 江苏宇田医药有限公司 一种用于合成西洛多辛的中间体的制备方法
CN106380438B (zh) * 2016-08-30 2019-07-30 江苏宇田医药有限公司 一种用于合成西洛多辛的吲哚啉衍生物的制备方法
CN106928118B (zh) * 2017-04-11 2022-08-23 常州瑞明药业有限公司 一种制备西洛多辛中间体的方法
EP3892615A1 (fr) 2020-04-09 2021-10-13 Minakem Procédé de préparation de silodosine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122010000031I1 (de) 1992-12-02 2010-10-21 Kissei Pharmaceutical Indolin Verbindungen zur Behandlung von Dysurien
JP4634560B2 (ja) 2000-01-14 2011-02-16 キッセイ薬品工業株式会社 光学活性なインドリン誘導体の製造方法およびその製造中間体
JP4921646B2 (ja) 2001-03-08 2012-04-25 キッセイ薬品工業株式会社 １−（３−ベンジルオキシプロピル）−５−（２−置換プロピル）インドリン誘導体およびその使用方法
RU2379289C2 (ru) 2004-10-27 2010-01-20 Киссеи Фармасьютикал Ко., Лтд. Соединение индолина и способ его получения
JP2006188470A (ja) * 2005-01-07 2006-07-20 Kissei Pharmaceut Co Ltd インドリン誘導体およびその製造方法
CN101993407B (zh) * 2009-08-27 2014-01-29 浙江华海药业股份有限公司 用于制备西洛多辛的吲哚啉化合物及其制备方法
CN101993406B (zh) * 2009-08-27 2014-01-15 浙江华海药业股份有限公司 光学活性的吲哚啉化合物及其制备方法
CN101993405B (zh) * 2009-08-27 2014-01-15 浙江华海药业股份有限公司 吲哚啉衍生物、及其制备方法和用途
CA2772997A1 (fr) * 2009-09-12 2011-03-17 Sandoz Ag Procede pour la preparation de derives d'indoline et leurs intermediaires
CN101759627A (zh) * 2009-09-15 2010-06-30 傅军 一种西洛多辛的制备新方法
WO2011124704A1 (fr) * 2010-04-09 2011-10-13 Ratiopharm Gmbh Procédé de préparation d'un intermédiaire pour la silodosine
WO2012131710A2 (fr) * 2011-03-30 2012-10-04 Panacea Biotec Ltd Nouveau procédé pour la synthèse de dérivés d'indoline

Also Published As

Publication number Publication date
ES2639196T3 (es) 2017-10-25
CN104302621A (zh) 2015-01-21
US20160176818A1 (en) 2016-06-23
US9938239B2 (en) 2018-04-10
EP2768806A1 (fr) 2014-08-27
EP2768806B1 (fr) 2017-05-31
WO2013056842A1 (fr) 2013-04-25
US20150038727A1 (en) 2015-02-05

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