MX347564B - Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo. - Google Patents
Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo.Info
- Publication number
- MX347564B MX347564B MX2014009948A MX2014009948A MX347564B MX 347564 B MX347564 B MX 347564B MX 2014009948 A MX2014009948 A MX 2014009948A MX 2014009948 A MX2014009948 A MX 2014009948A MX 347564 B MX347564 B MX 347564B
- Authority
- MX
- Mexico
- Prior art keywords
- formula
- methyl
- compound
- preparation
- difluoromethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La invención se refiere a un proceso para preparar un compuesto de fórmula I (ver Fórmula) donde R1, R2 y R3 son como se definen en la reivindicación 1, comprendiendo el proceso a) añadir un compuesto de fórmula II (ver Fórmula) en presencia de un disolvente orgánico inerte, a una mezcla que comprende un nitrito orgánico de fórmula III (R4-O-N=O (III)), donde R4 es alquilo C1-C8, un compuesto de fórmula IV (ver Fórmula) b) hacer reaccionar el compuesto resultante de fórmula V (ver Fórmula) con H2N-O-CH3 para obtener el compuesto de fórmula VII (ver Fórmula) c) reducir el compuesto de fórmula VII para obtener el compuesto de fórmula VIII (ver Fórmula) d) y hacer reaccionar el compuesto de fórmula VIII con un compuesto de fórmula IX (ver Fórmula) donde R* es halógeno, hidroxi o alcoxi C1-6, para obtener el compuesto de fórmula I.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12157354 | 2012-02-28 | ||
| PCT/EP2013/053773 WO2013127764A1 (en) | 2012-02-28 | 2013-02-26 | Process for the preparation of phenyl substituted 3 - difluoromethyl - 1 -methyl - 1h - pyrazole - 4 - carboxylic n-methoxy- [1 -methyl- 2 - phenylethyl] amides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014009948A MX2014009948A (es) | 2014-11-12 |
| MX347564B true MX347564B (es) | 2017-05-03 |
Family
ID=47748653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014009948A MX347564B (es) | 2012-02-28 | 2013-02-26 | Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9051272B2 (es) |
| EP (1) | EP2819997B1 (es) |
| JP (1) | JP6078563B2 (es) |
| KR (1) | KR102031809B1 (es) |
| CN (1) | CN104144914B (es) |
| AR (1) | AR090172A1 (es) |
| AU (1) | AU2013225123B2 (es) |
| BR (1) | BR112014020556B1 (es) |
| CA (1) | CA2863467C (es) |
| CO (1) | CO7051031A2 (es) |
| DK (1) | DK2819997T3 (es) |
| ES (1) | ES2558586T3 (es) |
| HR (1) | HRP20160001T1 (es) |
| HU (1) | HUE026564T2 (es) |
| IL (1) | IL233937A (es) |
| MX (1) | MX347564B (es) |
| PL (1) | PL2819997T3 (es) |
| TW (1) | TWI491594B (es) |
| WO (1) | WO2013127764A1 (es) |
| ZA (1) | ZA201405823B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106163281B (zh) | 2014-02-19 | 2019-03-15 | 巴斯夫农业公司 | 吡唑羧酸烷氧基酰胺的杀真菌组合物 |
| WO2016174042A1 (en) | 2015-04-27 | 2016-11-03 | BASF Agro B.V. | Pesticidal compositions |
| WO2017207368A1 (en) | 2016-06-02 | 2017-12-07 | BASF Agro B.V. | Fungicidal compositions |
| CN108610290B (zh) * | 2018-06-11 | 2020-04-24 | 武汉工程大学 | 一种氟唑菌酰羟胺的制备方法 |
| GB201818113D0 (en) | 2018-11-06 | 2018-12-19 | Syngenta Participations Ag | Process |
| GB201818117D0 (en) | 2018-11-06 | 2018-12-19 | Syngenta Participations Ag | Enantioselective process |
| GB201821036D0 (en) | 2018-12-21 | 2019-02-06 | Syngenta Participations Ag | Nematicidal compositions |
| US20240397947A1 (en) | 2021-01-22 | 2024-12-05 | Syngenta Crop Protection Ag | Method for the control or suppression of phytopathogenic bacteria |
| CN115703701B (zh) * | 2021-08-16 | 2024-06-25 | 上海晓明检测技术服务有限公司 | 一种微通道连续合成1-(2,4,6-三氯-苯基)-丙-2-酮的方法 |
| TW202412626A (zh) | 2022-08-16 | 2024-04-01 | 瑞士商先正達農作物保護股份公司 | 新用途 |
| CN117069611A (zh) * | 2023-07-12 | 2023-11-17 | 浙江工业大学 | 一种1-(2,4,6-三氯苯基)丙-2-酮o-甲基肟的制备方法 |
| WO2026027483A1 (en) | 2024-08-02 | 2026-02-05 | Syngenta Crop Protection Ag | Fungicidal treatment for panicle diseases in rice using n-methoxy(phenylethyl)-pyrazole carboxamides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1298349B1 (it) * | 1996-05-29 | 2000-01-05 | Alfa Chem Ital | Processo per la produzione di 1 - (3-trifluorometil) fenil-propan- 2-one intermedio nella sintesi della fenfluramina |
| JP2002531540A (ja) * | 1998-12-10 | 2002-09-24 | バイエル アクチェンゲゼルシャフト | ストロビルリン中間体の製造方法 |
| US7683092B2 (en) * | 2005-03-10 | 2010-03-23 | Merck Sharp & Dohme Corp. | Crystalline forms of antidiabetic compounds |
| MY152114A (en) * | 2008-12-05 | 2014-08-15 | Syngenta Participations Ag | Novel pyrazole-4-n-alkoxycarboxamides as microbiocides |
| WO2012021250A1 (en) * | 2010-07-13 | 2012-02-16 | Syngenta Participations Ag | Safener compositions and methods for reducing mycotoxins |
-
2013
- 2013-02-26 HR HRP20160001TT patent/HRP20160001T1/hr unknown
- 2013-02-26 JP JP2014559177A patent/JP6078563B2/ja active Active
- 2013-02-26 AU AU2013225123A patent/AU2013225123B2/en active Active
- 2013-02-26 US US14/374,547 patent/US9051272B2/en active Active
- 2013-02-26 KR KR1020147024947A patent/KR102031809B1/ko active Active
- 2013-02-26 HU HUE13705816A patent/HUE026564T2/hu unknown
- 2013-02-26 EP EP13705816.0A patent/EP2819997B1/en active Active
- 2013-02-26 CN CN201380011368.1A patent/CN104144914B/zh active Active
- 2013-02-26 WO PCT/EP2013/053773 patent/WO2013127764A1/en not_active Ceased
- 2013-02-26 BR BR112014020556-6A patent/BR112014020556B1/pt active IP Right Grant
- 2013-02-26 TW TW102106650A patent/TWI491594B/zh active
- 2013-02-26 CA CA2863467A patent/CA2863467C/en active Active
- 2013-02-26 MX MX2014009948A patent/MX347564B/es active IP Right Grant
- 2013-02-26 PL PL13705816T patent/PL2819997T3/pl unknown
- 2013-02-26 DK DK13705816.0T patent/DK2819997T3/en active
- 2013-02-26 ES ES13705816.0T patent/ES2558586T3/es active Active
- 2013-02-27 AR ARP130100601A patent/AR090172A1/es active IP Right Grant
-
2014
- 2014-08-04 IL IL233937A patent/IL233937A/en active IP Right Grant
- 2014-08-07 ZA ZA2014/05823A patent/ZA201405823B/en unknown
- 2014-08-26 CO CO14187079A patent/CO7051031A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2819997T3 (pl) | 2016-03-31 |
| IL233937A0 (en) | 2014-09-30 |
| JP2015508794A (ja) | 2015-03-23 |
| IL233937A (en) | 2016-04-21 |
| TW201348209A (zh) | 2013-12-01 |
| CO7051031A2 (es) | 2014-09-10 |
| KR102031809B1 (ko) | 2019-10-14 |
| AU2013225123B2 (en) | 2016-10-20 |
| HUE026564T2 (hu) | 2016-06-28 |
| AU2013225123A1 (en) | 2014-09-18 |
| TWI491594B (zh) | 2015-07-11 |
| DK2819997T3 (en) | 2016-01-18 |
| US9051272B2 (en) | 2015-06-09 |
| CA2863467A1 (en) | 2013-09-06 |
| CN104144914B (zh) | 2016-03-02 |
| CN104144914A (zh) | 2014-11-12 |
| EP2819997B1 (en) | 2015-10-28 |
| AR090172A1 (es) | 2014-10-22 |
| EP2819997A1 (en) | 2015-01-07 |
| US20150018562A1 (en) | 2015-01-15 |
| WO2013127764A1 (en) | 2013-09-06 |
| BR112014020556B1 (pt) | 2019-11-26 |
| CA2863467C (en) | 2020-03-10 |
| ES2558586T3 (es) | 2016-02-05 |
| JP6078563B2 (ja) | 2017-02-08 |
| KR20140138154A (ko) | 2014-12-03 |
| HRP20160001T1 (hr) | 2016-02-12 |
| MX2014009948A (es) | 2014-11-12 |
| ZA201405823B (en) | 2015-11-25 |
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Legal Events
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| FG | Grant or registration |