MX355542B - Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico. - Google Patents

Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico.

Info

Publication number
MX355542B
MX355542B MX2015002419A MX2015002419A MX355542B MX 355542 B MX355542 B MX 355542B MX 2015002419 A MX2015002419 A MX 2015002419A MX 2015002419 A MX2015002419 A MX 2015002419A MX 355542 B MX355542 B MX 355542B
Authority
MX
Mexico
Prior art keywords
haloalkyl
bis
pyrazole
carboxylic acid
acid derivatives
Prior art date
Application number
MX2015002419A
Other languages
English (en)
Other versions
MX2015002419A (es
Inventor
Jean-Pierre Vors
Sergii Pazenok
Florence Giornal
Frédéric R Leroux
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2015002419A publication Critical patent/MX2015002419A/es
Publication of MX355542B publication Critical patent/MX355542B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se describe un nuevo procedimiento para la preparación de derivados de 3,5-bis(haloalquil)-pirazol de la fórmula general (I) (ver Fórmula) resultante de la reacción of derivados de ácido 3,5-bis(haloalquil)-pirazol-4-carboxílico de la fórmula general (Ila) (ver Fórmula) con un compuesto de cobre y una base a temperatura elevada en la que R1 está seleccionado de H, alquilo C1-12, cicloalquilo C3-8, arilo C6-18, arilalquilo C7-19 o alquilarilo C7-19, CH2CN, CH2CX3, CH2COOH, CH2COOalquilo C1-12, y X es independientemente uno de otro F, CI, Br, I; R2 y R3 están seleccionados independientemente uno de otro de haloalquilo C1-C6.
MX2015002419A 2012-08-30 2013-08-28 Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico. MX355542B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12356019 2012-08-30
PCT/EP2013/067809 WO2014033164A1 (en) 2012-08-30 2013-08-28 Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
MX2015002419A MX2015002419A (es) 2015-11-06
MX355542B true MX355542B (es) 2018-04-20

Family

ID=47044930

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015002419A MX355542B (es) 2012-08-30 2013-08-28 Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico.

Country Status (12)

Country Link
US (1) US9145370B2 (es)
EP (1) EP2890682B1 (es)
JP (1) JP5931291B2 (es)
KR (1) KR102140620B1 (es)
CN (1) CN104703972B (es)
BR (1) BR112015004097B1 (es)
DK (1) DK2890682T3 (es)
ES (1) ES2588386T3 (es)
IL (1) IL237203A (es)
MX (1) MX355542B (es)
TW (1) TWI609005B (es)
WO (1) WO2014033164A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI651306B (zh) * 2014-03-24 2019-02-21 德商拜耳作物科學股份有限公司 自α,α－二鹵胺類與酮亞胺類製備３，５－雙（鹵烷基）吡唑衍生物之方法
EP3015458A1 (en) * 2014-11-03 2016-05-04 Bayer CropScience AG Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from a,a-dihaloamines and ketimines
ES2672581T3 (es) * 2014-06-11 2018-06-15 Bayer Cropscience Aktiengesellschaft Proceso para la preparación de 3,5-bis(haloalquil)pirazoles por medio de la acilación de cetiminas
ES2672577T3 (es) * 2014-06-11 2018-06-15 Bayer Cropscience Aktiengesellschaft Proceso para preparar derivados de 3,5-bis(haloalquil)pirazol por medio de la acilación de Hidrazonas
MX2017017140A (es) * 2015-06-26 2018-03-09 Bayer Cropscience Ag Proceso para la preparacion de pirazoles sustituidos que contienen grupos haloalcoxi-y haloalquiltio a partir de a,a-dihaloalquilaminas y quetiminas.
EP3178813A1 (en) 2015-12-09 2017-06-14 Basf Se Method for preparing halogenated 3-oxocarboxylates carrying a 2-alkoxymethylidene or a 2-dialkylaminomethylidene group
SG11202007328UA (en) 2018-02-01 2020-08-28 Myokardia Inc Pyrazole compounds and preparation thereof
EP3807250A1 (en) 2018-06-18 2021-04-21 Bayer Aktiengesellschaft Disubstituted 5(3)-pyrazole carboxylates and a process for their preparation from enolates and fluoroalkylaminoreagents (far) reagents

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200738701A (en) 2005-07-26 2007-10-16 Du Pont Fungicidal carboxamides
WO2008013622A2 (en) 2006-07-27 2008-01-31 E. I. Du Pont De Nemours And Company Fungicidal azocyclic amides
DE102006039909A1 (de) 2006-08-25 2008-03-13 Bayer Cropscience Ag Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten
WO2008091594A2 (en) 2007-01-24 2008-07-31 E. I. Du Pont De Nemours And Company Fungicidal mixtures
PL2121660T3 (pl) 2007-01-25 2015-06-30 Du Pont Amidy grzybobójcze
TWI428091B (zh) 2007-10-23 2014-03-01 Du Pont 殺真菌劑混合物
BRPI0905758A2 (pt) 2008-01-25 2015-07-14 Du Pont Composto, método de controle de doenças de plantas e composição fungicida
MX2010008102A (es) 2008-01-25 2010-08-04 Du Pont Compuestos fungicidas heterociclicos.
MX2010011879A (es) 2008-04-30 2010-12-06 Bayer Cropscience Ag Esteres y tioesteres del acido tiazol-4-carboxilico como agentes fitoprotectores.
EP2334669B1 (de) 2008-10-01 2015-12-23 Bayer Intellectual Property GmbH Heterocyclyl substituierte thiazole als pflanzenschutzmittel
TW201036966A (en) 2008-12-02 2010-10-16 Du Pont Fungicidal heterocyclic compounds
EP2376487B1 (de) 2008-12-11 2016-01-06 Bayer Intellectual Property GmbH Thiazolyoximether und -hydrazone als pflanzenschutzmittel
TWI508962B (zh) 2009-04-22 2015-11-21 Du Pont 氮雜環醯胺之固體形態
EP2272846A1 (de) 2009-06-23 2011-01-12 Bayer CropScience AG Thiazolylpiperidin Derivate als Fungizide
WO2011051243A1 (en) 2009-10-29 2011-05-05 Bayer Cropscience Ag Active compound combinations
JP5785560B2 (ja) 2009-12-21 2015-09-30 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 殺真菌剤としてのビス（ジフルオロメチル）ピラゾール
US8835427B2 (en) 2010-01-07 2014-09-16 E I Du Pont De Nemours And Company Fungicidal heterocyclic compounds

Also Published As

Publication number Publication date
US20150225350A1 (en) 2015-08-13
IL237203A0 (en) 2015-04-30
EP2890682B1 (en) 2016-06-29
CN104703972B (zh) 2017-05-31
MX2015002419A (es) 2015-11-06
DK2890682T3 (en) 2016-09-12
BR112015004097A2 (pt) 2019-10-22
JP5931291B2 (ja) 2016-06-08
TWI609005B (zh) 2017-12-21
JP2015531342A (ja) 2015-11-02
CN104703972A (zh) 2015-06-10
ES2588386T3 (es) 2016-11-02
WO2014033164A1 (en) 2014-03-06
EP2890682A1 (en) 2015-07-08
US9145370B2 (en) 2015-09-29
KR102140620B1 (ko) 2020-08-03
TW201422589A (zh) 2014-06-16
KR20150046292A (ko) 2015-04-29
BR112015004097B1 (pt) 2020-02-18
IL237203A (en) 2016-11-30

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