MX2015002419A - Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico. - Google Patents
Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico.Info
- Publication number
- MX2015002419A MX2015002419A MX2015002419A MX2015002419A MX2015002419A MX 2015002419 A MX2015002419 A MX 2015002419A MX 2015002419 A MX2015002419 A MX 2015002419A MX 2015002419 A MX2015002419 A MX 2015002419A MX 2015002419 A MX2015002419 A MX 2015002419A
- Authority
- MX
- Mexico
- Prior art keywords
- haloalkyl
- bis
- pyrazole
- carboxylic acid
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Se describe un nuevo procedimiento para la preparación de derivados de 3,5-bis(haloalquil)-pirazol de la fórmula general (I) (ver Fórmula) resultante de la reacción of derivados de ácido 3,5-bis(haloalquil)-pirazol-4-carboxílico de la fórmula general (Ila) (ver Fórmula) con un compuesto de cobre y una base a temperatura elevada en la que R1 está seleccionado de H, alquilo C1-12, cicloalquilo C3-8, arilo C6-18, arilalquilo C7-19 o alquilarilo C7-19, CH2CN, CH2CX3, CH2COOH, CH2COOalquilo C1-12, y X es independientemente uno de otro F, CI, Br, I; R2 y R3 están seleccionados independientemente uno de otro de haloalquilo C1-C6.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12356019 | 2012-08-30 | ||
PCT/EP2013/067809 WO2014033164A1 (en) | 2012-08-30 | 2013-08-28 | Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015002419A true MX2015002419A (es) | 2015-11-06 |
MX355542B MX355542B (es) | 2018-04-20 |
Family
ID=47044930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015002419A MX355542B (es) | 2012-08-30 | 2013-08-28 | Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico. |
Country Status (12)
Country | Link |
---|---|
US (1) | US9145370B2 (es) |
EP (1) | EP2890682B1 (es) |
JP (1) | JP5931291B2 (es) |
KR (1) | KR102140620B1 (es) |
CN (1) | CN104703972B (es) |
BR (1) | BR112015004097B1 (es) |
DK (1) | DK2890682T3 (es) |
ES (1) | ES2588386T3 (es) |
IL (1) | IL237203A (es) |
MX (1) | MX355542B (es) |
TW (1) | TWI609005B (es) |
WO (1) | WO2014033164A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3015458A1 (en) * | 2014-11-03 | 2016-05-04 | Bayer CropScience AG | Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from a,a-dihaloamines and ketimines |
EP3122727B1 (en) * | 2014-03-24 | 2018-01-31 | Bayer CropScience Aktiengesellschaft | Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from alpha , alpha-dihaloamines and ketimines |
MX2016016396A (es) | 2014-06-11 | 2017-04-06 | Bayer Cropscience Ag | Proceso para preparar derivados de 3,5-bis(haloalquil)pirazol por medio de la acilacion de hidrazonas. |
MX2016016399A (es) * | 2014-06-11 | 2017-04-06 | Bayer Cropscience Ag | Proceso para la preparacion de 3,5-bis(haloalquil)pirazoles por medio de la acilacion de cetiminas. |
MX2017017140A (es) | 2015-06-26 | 2018-03-09 | Bayer Cropscience Ag | Proceso para la preparacion de pirazoles sustituidos que contienen grupos haloalcoxi-y haloalquiltio a partir de a,a-dihaloalquilaminas y quetiminas. |
EP3178813A1 (en) | 2015-12-09 | 2017-06-14 | Basf Se | Method for preparing halogenated 3-oxocarboxylates carrying a 2-alkoxymethylidene or a 2-dialkylaminomethylidene group |
WO2019150392A1 (en) | 2018-02-01 | 2019-08-08 | Srf Limited | Pyrazole compounds and preparation thereof |
CN112351972A (zh) | 2018-06-18 | 2021-02-09 | 拜耳公司 | 二取代的5(3)-吡唑羧酸酯及由烯醇酯和氟烷基氨基(far)试剂制备其的方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200738701A (en) | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
WO2008013622A2 (en) | 2006-07-27 | 2008-01-31 | E. I. Du Pont De Nemours And Company | Fungicidal azocyclic amides |
DE102006039909A1 (de) | 2006-08-25 | 2008-03-13 | Bayer Cropscience Ag | Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten |
WO2008091594A2 (en) | 2007-01-24 | 2008-07-31 | E. I. Du Pont De Nemours And Company | Fungicidal mixtures |
CN101622245B (zh) | 2007-01-25 | 2014-09-10 | 纳幕尔杜邦公司 | 杀真菌酰胺 |
TWI428091B (zh) | 2007-10-23 | 2014-03-01 | Du Pont | 殺真菌劑混合物 |
AU2009206468B2 (en) | 2008-01-25 | 2014-01-09 | E. I. Du Pont De Nemours And Company | Fungicidal heterocyclic compounds |
MX2010007974A (es) | 2008-01-25 | 2010-08-04 | Du Pont | Amidas fungicidas. |
AU2009243401A1 (en) | 2008-04-30 | 2009-11-05 | Bayer Cropscience Ag | Thiazol-4-carboxylic acid esters and thioesters as plant protection agents |
EP2334669B1 (de) | 2008-10-01 | 2015-12-23 | Bayer Intellectual Property GmbH | Heterocyclyl substituierte thiazole als pflanzenschutzmittel |
ES2452299T3 (es) | 2008-12-02 | 2014-03-31 | E. I. Du Pont De Nemours And Company | Compuestos heterocíclicos fungicidas |
WO2010066353A1 (de) | 2008-12-11 | 2010-06-17 | Bayer Cropscience Ag | Thiazolyoximether und -hydrazone asl pflanzenschutzmittel |
TWI508962B (zh) | 2009-04-22 | 2015-11-21 | Du Pont | 氮雜環醯胺之固體形態 |
EP2272846A1 (de) | 2009-06-23 | 2011-01-12 | Bayer CropScience AG | Thiazolylpiperidin Derivate als Fungizide |
WO2011051243A1 (en) | 2009-10-29 | 2011-05-05 | Bayer Cropscience Ag | Active compound combinations |
WO2011076699A1 (de) | 2009-12-21 | 2011-06-30 | Bayer Cropscience Ag | Bis(difluormethyl)pyrazole als fungizide |
BR112012016733A2 (pt) | 2010-01-07 | 2015-09-01 | Du Pont | "composto, composição fungicida e método" |
-
2013
- 2013-08-28 MX MX2015002419A patent/MX355542B/es active IP Right Grant
- 2013-08-28 KR KR1020157007647A patent/KR102140620B1/ko active IP Right Grant
- 2013-08-28 BR BR112015004097-7A patent/BR112015004097B1/pt active IP Right Grant
- 2013-08-28 DK DK13758796.0T patent/DK2890682T3/en active
- 2013-08-28 JP JP2015529002A patent/JP5931291B2/ja active Active
- 2013-08-28 EP EP13758796.0A patent/EP2890682B1/en active Active
- 2013-08-28 CN CN201380045648.4A patent/CN104703972B/zh active Active
- 2013-08-28 ES ES13758796.0T patent/ES2588386T3/es active Active
- 2013-08-28 WO PCT/EP2013/067809 patent/WO2014033164A1/en active Application Filing
- 2013-08-28 US US14/422,891 patent/US9145370B2/en active Active
- 2013-08-29 TW TW102130963A patent/TWI609005B/zh active
-
2015
- 2015-02-12 IL IL237203A patent/IL237203A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
DK2890682T3 (en) | 2016-09-12 |
EP2890682B1 (en) | 2016-06-29 |
TWI609005B (zh) | 2017-12-21 |
JP2015531342A (ja) | 2015-11-02 |
BR112015004097B1 (pt) | 2020-02-18 |
IL237203A0 (en) | 2015-04-30 |
CN104703972A (zh) | 2015-06-10 |
IL237203A (en) | 2016-11-30 |
JP5931291B2 (ja) | 2016-06-08 |
US20150225350A1 (en) | 2015-08-13 |
TW201422589A (zh) | 2014-06-16 |
KR102140620B1 (ko) | 2020-08-03 |
CN104703972B (zh) | 2017-05-31 |
US9145370B2 (en) | 2015-09-29 |
EP2890682A1 (en) | 2015-07-08 |
BR112015004097A2 (pt) | 2019-10-22 |
MX355542B (es) | 2018-04-20 |
ES2588386T3 (es) | 2016-11-02 |
WO2014033164A1 (en) | 2014-03-06 |
KR20150046292A (ko) | 2015-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2015002419A (es) | Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico. | |
TW201129555A (en) | Process for the manufacture of dabigatrane etexilate | |
IN2014CN01136A (es) | ||
IN2012DN02751A (es) | ||
SG158829A1 (en) | New process for the synthesis of agomelatine | |
WO2014108919A3 (en) | NOVEL INTERMEDIATE AND POLYMORPHS OF 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-c] PYRIDINE-3-CARBOXAMIDE AND PROCESS THEREOF | |
GEP20125512B (en) | Process for synthesis of agomelatin | |
MX2011007998A (es) | Nuevos herbicidas. | |
MY161132A (en) | Novel herbicides | |
WO2015082422A3 (en) | Process for reacting chemical compounds | |
MX2011007932A (es) | Herbicidas nuevos. | |
MX347564B (es) | Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo. | |
MX2014006992A (es) | Disales de acido malonico y metodo para preparar dihaluros de malonilo. | |
HK1152292A1 (en) | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)- cyclopropanecarboxylic acid | |
IN2014DN08840A (es) | ||
PL401473A1 (pl) | Nowe, silnie fluorescencyjne substancje heterocykliczne i sposób ich otrzymywania | |
HK1168102A1 (en) | Process for the preparation of a compound useful as an inhibitor of tafia | |
PL397479A1 (pl) | Nowe, fluorescencyjne barwniki heterocykliczne i sposób ich otrzymywania | |
MX2015000668A (es) | Procedimiento de preparacion de 5-fluoro-1h-pirazoles. | |
UA105843C2 (uk) | Спосіб одержання кремнієвмісних азодикарбамідів | |
UA106195C2 (ru) | Способ синтеза агомелатина | |
TN2011000474A1 (en) | Pyrazole compound | |
UA102816C2 (ru) | Способ синтеза кристаллической формы v агомелатина | |
MX2013004193A (es) | Procedimiento para la preparacion de derivados de acido 3-(6-amino-piridin-3-il)-2-acrilico. | |
WO2011012620A3 (en) | Processes for the alkylation of pyrazoles |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |