IN2014DN11207A - - Google Patents
Info
- Publication number
- IN2014DN11207A IN2014DN11207A IN11207DEN2014A IN2014DN11207A IN 2014DN11207 A IN2014DN11207 A IN 2014DN11207A IN 11207DEN2014 A IN11207DEN2014 A IN 11207DEN2014A IN 2014DN11207 A IN2014DN11207 A IN 2014DN11207A
- Authority
- IN
- India
- Prior art keywords
- rifaximin
- comprised
- amino acids
- compositions
- present
- Prior art date
Links
- NZCRJKRKKOLAOJ-XRCRFVBUSA-N rifaximin Chemical compound OC1=C(C(O)=C2C)C3=C4N=C5C=C(C)C=CN5C4=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O NZCRJKRKKOLAOJ-XRCRFVBUSA-N 0.000 abstract 9
- 229960003040 rifaximin Drugs 0.000 abstract 9
- 150000001413 amino acids Chemical class 0.000 abstract 7
- 239000000203 mixture Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000368A ITBO20120368A1 (it) | 2012-07-06 | 2012-07-06 | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
| PCT/IB2013/055448 WO2014006576A1 (en) | 2012-07-06 | 2013-07-03 | Pharmaceutical compositions comprising rifaximin and amino acids, preparation method and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN11207A true IN2014DN11207A (ko) | 2015-10-02 |
Family
ID=46939741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN11207DEN2014 IN2014DN11207A (ko) | 2012-07-06 | 2013-07-03 |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US9452157B2 (ko) |
| EP (2) | EP3127909A1 (ko) |
| JP (1) | JP6150888B2 (ko) |
| KR (1) | KR101880255B1 (ko) |
| CN (1) | CN104395322B (ko) |
| AU (1) | AU2013285085B2 (ko) |
| BR (1) | BR112015000088B1 (ko) |
| CA (1) | CA2874815C (ko) |
| CL (1) | CL2015000019A1 (ko) |
| DK (1) | DK2870163T3 (ko) |
| EA (1) | EA028769B1 (ko) |
| ES (1) | ES2691971T3 (ko) |
| IL (1) | IL235992B (ko) |
| IN (1) | IN2014DN11207A (ko) |
| IT (1) | ITBO20120368A1 (ko) |
| MX (1) | MX366193B (ko) |
| NZ (1) | NZ703120A (ko) |
| PL (1) | PL2870163T3 (ko) |
| PT (1) | PT2870163T (ko) |
| SG (1) | SG11201408277UA (ko) |
| TN (1) | TN2014000530A1 (ko) |
| UA (1) | UA114512C2 (ko) |
| WO (1) | WO2014006576A1 (ko) |
| ZA (1) | ZA201408990B (ko) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1698630E (pt) | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| JP6576953B2 (ja) | 2014-05-12 | 2019-09-18 | アルファシグマ ソシエタ ペル アチオニ | リファキシミンの新規溶媒和物結晶形、生成物、組成物及びそれらの使用 |
| WO2016204474A2 (ko) * | 2015-06-18 | 2016-12-22 | 주식회사대성미생물연구소 | 리팍시민 결정체를 포함하는 동물 장염 치료용 수의학적 조성물 |
| JP7026624B2 (ja) * | 2016-02-03 | 2022-02-28 | フイルメニツヒ ソシエテ アノニム | アミド化合物の溶液及び分散液 |
| AU2017326253B2 (en) | 2016-09-13 | 2021-10-21 | Allergan, Inc. | Stabilized non-protein clostridial toxin compositions |
| MX2018004788A (es) * | 2018-04-18 | 2019-10-21 | Alparis Sa De Cv | Nuevas fases solidas de rifaximina. |
| WO2020208140A1 (en) * | 2019-04-12 | 2020-10-15 | Sandoz Ag | Rifaximin-containing granules |
| KR102154309B1 (ko) | 2019-07-05 | 2020-09-09 | 주식회사 비오엑스 | 테이프 없이 포장가능한 포장상자 |
| KR102312848B1 (ko) | 2019-12-11 | 2021-10-15 | 주식회사 비오엑스 | 테이프 없이 포장가능한 포장상자 |
| KR102252978B1 (ko) | 2019-12-11 | 2021-05-18 | 주식회사 비오엑스 | 테이프 없이 포장가능한 포장상자 |
| KR102182587B1 (ko) | 2020-01-22 | 2020-11-24 | 주식회사 비오엑스 | 밀폐구조를 갖는 포장상자 |
| KR20220151991A (ko) | 2021-05-07 | 2022-11-15 | 주식회사 비오엑스 | 테이프 없이 포장 가능한 포장상자 |
| KR102674188B1 (ko) | 2022-01-13 | 2024-06-12 | 주식회사 비오엑스 | 테이프 없이 포장 가능한 포장상자 |
Family Cites Families (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2043847A1 (ko) | 1969-05-30 | 1971-02-19 | Takeda Chemical Industries Ltd | |
| CH571064A5 (en) | 1973-03-01 | 1975-12-31 | Archifar Ind Chim Trentino | Recovery of rieamycin from broths - by oxidn to an insol form |
| US4267274A (en) | 1973-04-26 | 1981-05-12 | Gruppo Lepetit S.P.A. | Streptomyces mediterranei mutant capable of production of rifamycin B |
| GB1470426A (en) | 1974-08-30 | 1977-04-14 | Lepetit Spa | Rifamycins |
| JPS6021570B2 (ja) * | 1978-07-04 | 1985-05-28 | 三共株式会社 | ド−パ類の高濃度製剤の製法 |
| IT1154655B (it) | 1980-05-22 | 1987-01-21 | Alfa Farmaceutici Spa | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
| JPS57209211A (en) * | 1981-06-18 | 1982-12-22 | Shiseido Co Ltd | Antimicrobial composition |
| CA1215976A (en) | 1984-05-15 | 1986-12-30 | Vincenzo Cannata | New process for the synthesis of imidazo rifamycins |
| IT1199374B (it) | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
| IT1199413B (it) | 1984-09-26 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
| US4816568A (en) | 1986-05-16 | 1989-03-28 | International Minerals & Chemical Corp. | Stabilization of growth hormones |
| US5356625A (en) | 1986-08-28 | 1994-10-18 | Enzacor Properties Limited | Microgranular preparation useful in the delivery of biologically active materials to the intestinal regions of animals |
| GB8816620D0 (en) | 1988-07-13 | 1988-08-17 | Lepetit Spa | Rifapentine hydrohalides |
| DE69111607T2 (de) | 1990-06-29 | 1995-12-21 | Lepetit Spa | Reine kristalline form von rifapentin. |
| US5284512A (en) | 1991-03-06 | 1994-02-08 | Donlar Corporation | Polyaspartic acid and its salts for dispersing suspended solids |
| RO111990B1 (ro) | 1991-12-20 | 1997-04-30 | Novo Nordisk As | Preparate farmaceutice, continand un hormon de crestere sau un derivat al acestuia, si procedeu de preparare |
| WO1993013792A1 (en) | 1992-01-13 | 1993-07-22 | Pitman-Moore, Inc. | Delayed release device for transition metal/protein complexes |
| JPH08502021A (ja) | 1992-04-07 | 1996-03-05 | マリンクロッド・ヴェタラネリィ・インコーポレイテッド | 生体相容性ソマトトロピン溶液 |
| US5840332A (en) | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
| DK0935417T3 (da) | 1996-10-16 | 2009-08-10 | Napo Pharmaceuticals Inc | Enteroformuleringer af proanthocyanidin-polymer-sammensætninger mod diarré |
| US20030059471A1 (en) | 1997-12-15 | 2003-03-27 | Compton Bruce Jon | Oral delivery formulation |
| US6042816A (en) | 1998-08-19 | 2000-03-28 | The Gillette Company | Enhanced antiperspirant salts stabilized with calcium and concentrated aqueous solutions of such salts |
| UA75365C2 (en) | 2000-08-16 | 2006-04-17 | Bristol Myers Squibb Co | Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon |
| JP4180368B2 (ja) | 2000-10-31 | 2008-11-12 | サンド・アクチエンゲゼルシヤフト | 塩酸ベンラファキシンの結晶形 |
| IL156055A0 (en) | 2000-11-30 | 2003-12-23 | Teva Pharma | Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms |
| US6902723B2 (en) | 2003-08-14 | 2005-06-07 | The Gillette Company | Enhanced efficacy antiperspirant compositions containing strontium |
| US7902206B2 (en) | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
| US7906542B2 (en) | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
| US20080262024A1 (en) | 2003-11-07 | 2008-10-23 | Giuseppe Claudio Viscomi | Rifaximin compositions and method of use |
| US7923553B2 (en) | 2003-11-07 | 2011-04-12 | Alfa Wassermann, S.P.A. | Processes for the production of polymorphic forms of rifaximin |
| ITMI20032144A1 (it) | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
| US20050196418A1 (en) * | 2004-03-04 | 2005-09-08 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
| PT1698630E (pt) | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| ITBO20050123A1 (it) * | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
| ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
| NZ575550A (en) | 2006-09-22 | 2011-12-22 | Cipla Ltd | Rifaximin |
| ITMI20071241A1 (it) | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
| DK2011486T3 (da) | 2007-07-06 | 2012-09-03 | Lupin Ltd | Farmaceutiske sammensætninger af rifaximin |
| US8974825B2 (en) | 2007-07-06 | 2015-03-10 | Lupin Limited | Pharmaceutical compositions for gastrointestinal drug delivery |
| AU2008273699A1 (en) | 2007-07-06 | 2009-01-15 | Lupin Limited | Pharmaceutical compositions of rifaximin |
| US7709634B2 (en) | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
| EA021176B1 (ru) * | 2008-02-25 | 2015-04-30 | Сэликс Фармасьютиклз, Лтд. | Полиморфная форма рифаксимина и её применение |
| US8486956B2 (en) | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
| WO2010040020A1 (en) * | 2008-10-02 | 2010-04-08 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| US7928115B2 (en) * | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
| WO2010044093A1 (en) | 2008-10-16 | 2010-04-22 | Strides Arcolab Limited | Formulations containing rifaximin |
| KR20110107806A (ko) | 2008-12-10 | 2011-10-04 | 시플라 리미티드 | 리팍시민 복합체 |
| IT1397617B1 (it) | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
| JP5643297B2 (ja) | 2009-05-19 | 2014-12-17 | ニューロデルム リミテッド | ドーパデカルボキシラーゼ阻害剤の連続投与のための組成物 |
| AU2010312309B2 (en) | 2009-10-26 | 2016-10-06 | Thomas Julius Borody | Novel enteric combination therapy |
| PE20121185A1 (es) | 2009-10-27 | 2012-09-15 | Lupin Ltd | Dispersion solida de rifaximina |
| WO2011061748A1 (en) | 2009-11-19 | 2011-05-26 | Strides Arcolab Limited | Rifaximin premix |
| KR20120099731A (ko) | 2009-11-23 | 2012-09-11 | 시플라 리미티드 | 국소용 폼 조성물 |
| CA2781580A1 (en) | 2009-11-23 | 2011-05-26 | Cipla Limited | Topical foam composition |
| US8952159B2 (en) | 2009-12-28 | 2015-02-10 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
| CN101773465B (zh) * | 2010-01-19 | 2012-11-07 | 南京泛太化工医药研究所 | 以氨基酸为稳定剂的聚合物胶束载药系统 |
| IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
| US9211258B2 (en) | 2010-03-10 | 2015-12-15 | Lupin Limited | Rifaximin ready-to-use suspension |
| CN103269587A (zh) | 2010-06-03 | 2013-08-28 | 萨利克斯药品有限公司 | 利福昔明的新形式及其用途 |
| EP2582707A4 (en) | 2010-06-16 | 2014-01-08 | Apotex Pharmachem Inc | POLYMORPHIC FORMS OF RIFAXIMINE |
| MY165086A (en) | 2010-07-12 | 2018-02-28 | Salix Pharmaceuticals Ltd | Formulations of rifaximin and uses thereof |
| EP2616044A1 (en) | 2010-09-13 | 2013-07-24 | Cilpa Limited | Pharmaceutical composition |
| WO2012035544A2 (en) | 2010-09-13 | 2012-03-22 | Sequent Scientific Ltd. | A novel polymorphic form of rifaximin and process for its preparation |
| WO2012076832A1 (en) * | 2010-12-09 | 2012-06-14 | Cipla Limited | Suppositories comprising rifaximin |
| CN103827122B (zh) | 2011-02-11 | 2016-08-31 | 萨利克斯药品有限公司 | 利福昔明的形式及其用途 |
| AU2012251385A1 (en) | 2011-05-02 | 2013-11-21 | Ranbaxy Laboratories Limited | Rifaximin dimethylformamide solvate |
| ITMI20110890A1 (it) | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
| WO2012155981A1 (en) | 2011-05-19 | 2012-11-22 | Friulchem Spa | New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby |
| CA2861104A1 (en) | 2012-01-25 | 2013-08-01 | Salix Pharmaceuticals, Ltd. | Rifaximin derivative and uses thereof |
| CA2876737A1 (en) | 2012-06-13 | 2013-12-19 | Apotex Pharmachem Inc. | Polymorphic forms of rifaximin |
| WO2014091432A1 (en) | 2012-12-12 | 2014-06-19 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of rifaximin |
| ITMI20131307A1 (it) | 2013-08-02 | 2015-02-02 | A M S A Anonima Materie Sint & Affini S P A | Processo per la preparazione di refaximina k |
-
2012
- 2012-07-06 IT IT000368A patent/ITBO20120368A1/it unknown
-
2013
- 2013-07-03 CA CA2874815A patent/CA2874815C/en active Active
- 2013-07-03 AU AU2013285085A patent/AU2013285085B2/en not_active Ceased
- 2013-07-03 US US13/935,331 patent/US9452157B2/en active Active
- 2013-07-03 CN CN201380033964.XA patent/CN104395322B/zh not_active Expired - Fee Related
- 2013-07-03 ES ES13739813.7T patent/ES2691971T3/es active Active
- 2013-07-03 DK DK13739813.7T patent/DK2870163T3/en active
- 2013-07-03 MX MX2014015799A patent/MX366193B/es active IP Right Grant
- 2013-07-03 BR BR112015000088A patent/BR112015000088B1/pt not_active IP Right Cessation
- 2013-07-03 PT PT13739813T patent/PT2870163T/pt unknown
- 2013-07-03 EA EA201492126A patent/EA028769B1/ru not_active IP Right Cessation
- 2013-07-03 NZ NZ703120A patent/NZ703120A/en not_active IP Right Cessation
- 2013-07-03 UA UAA201412919A patent/UA114512C2/uk unknown
- 2013-07-03 PL PL13739813T patent/PL2870163T3/pl unknown
- 2013-07-03 KR KR1020157000175A patent/KR101880255B1/ko not_active Application Discontinuation
- 2013-07-03 SG SG11201408277UA patent/SG11201408277UA/en unknown
- 2013-07-03 EP EP16187004.3A patent/EP3127909A1/en not_active Withdrawn
- 2013-07-03 EP EP13739813.7A patent/EP2870163B1/en active Active
- 2013-07-03 WO PCT/IB2013/055448 patent/WO2014006576A1/en active Application Filing
- 2013-07-03 JP JP2015519474A patent/JP6150888B2/ja not_active Expired - Fee Related
- 2013-07-03 IN IN11207DEN2014 patent/IN2014DN11207A/en unknown
-
2014
- 2014-11-30 IL IL235992A patent/IL235992B/en active IP Right Grant
- 2014-12-08 ZA ZA2014/08990A patent/ZA201408990B/en unknown
- 2014-12-24 TN TN2014000530A patent/TN2014000530A1/fr unknown
-
2015
- 2015-01-06 CL CL2015000019A patent/CL2015000019A1/es unknown
-
2016
- 2016-08-11 US US15/235,070 patent/US20170189385A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014DN11207A (ko) | ||
| HRP20151263T1 (hr) | Natrijeva sol 6-fluoro-3-hidroksi-2-pirazinkarboksamida | |
| IN2012DE00337A (ko) | ||
| AU2018236805B2 (en) | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | |
| PH12014502041A1 (en) | Heterocyclyl compounds as mek inhibitors | |
| EA201291348A1 (ru) | Активаторы растворимой гуанилатциклазы | |
| MX366393B (es) | Sales o co-cristales de 3-(3-dimetilamino-1-etil-2-metil-propil)-f enol. | |
| JP2013520405A5 (ko) | ||
| HRP20210699T1 (hr) | Izmijenjeni kolagen | |
| NZ602450A (en) | Agomelatine hydrochloride hydrate and preparation thereof | |
| EA201171399A1 (ru) | Способ и композиция для улучшения всасывания лекарственных средств | |
| NZ620040A (en) | Formulations of deoxycholic acid and salts thereof | |
| RU2011131609A (ru) | Способ получения литиевой соли коменовой кислоты и применение ее как антиоксидантного, стресс- и нейропротекторного средства | |
| WO2014006635A3 (en) | Solid oral compositions of silodosin | |
| EA201591487A1 (ru) | Производные замещенной бисфенилбутановой кислоты в качестве ингибиторов nep с улучшенной in vivo эффективностью | |
| EA201590244A1 (ru) | Способ изготовления средства для лечения туберкулеза | |
| PL409976A1 (pl) | Sposób otrzymywania dodatku do żywności do stabilizacji tekstury albo zagęszczania, zwłaszcza z wytłoków jabłkowych oraz dodatek otrzymany tym sposobem | |
| JP2011136218A5 (ko) | ||
| TH110601B (th) | กระบวนการแบบใหม่สำหรับการสังเคราะห์ของไอวาบราดีน และเกลือของการเติมของสิ่งนี้ด้วยกรดที่ยอมรับได้ทางเภสัชกรรม | |
| UA102463U (xx) | Стабілізований розчин | |
| UA102461U (xx) | Фармацевтична композиція | |
| RU2014150120A (ru) | Способ получения биологически активного фторида кальция и способы его применения для профилактики и лечения фтордефицитных состояний у детей и подростков | |
| TH143299A (th) | การรวมตัวของผลึกนาล็อกโซล | |
| TH146679A (th) | เกลือโซเดียมของ 6-ฟลูออโร-3-ไฮดรอกซิ-2-พิแรซีน คาร์บอกแซมีด | |
| TH131398A (th) | กระบวนการสำหรับการผลิตของสารออกฤทธิ์ทางเภสัชกรรม |