EA201171399A1 - Способ и композиция для улучшения всасывания лекарственных средств - Google Patents

Способ и композиция для улучшения всасывания лекарственных средств

Info

Publication number
EA201171399A1
EA201171399A1 EA201171399A EA201171399A EA201171399A1 EA 201171399 A1 EA201171399 A1 EA 201171399A1 EA 201171399 A EA201171399 A EA 201171399A EA 201171399 A EA201171399 A EA 201171399A EA 201171399 A1 EA201171399 A1 EA 201171399A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tablet
active ingredient
medicines
composition
medically active
Prior art date
Application number
EA201171399A
Other languages
English (en)
Inventor
Эрик Р. Ферст
Эшиш Б. Пэтель
Гидо Шмитц
Стефани Петэвей-Хиксон
Ханг-Хуар Тонг
Original Assignee
БАЙЕР ХЕЛЬСКЕР ЛЛСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43062708&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201171399(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by БАЙЕР ХЕЛЬСКЕР ЛЛСи filed Critical БАЙЕР ХЕЛЬСКЕР ЛЛСи
Publication of EA201171399A1 publication Critical patent/EA201171399A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Таблетка с улучшенным профилем растворимости активного с медицинской точки зрения ингредиента, такого как ацетилсалициловая кислота, и способы изготовления таблетки. Таблетка содержит смесь кристаллов активного с медицинской точки зрения ингредиента и вспомогательное вещество, способствующее растворению, такое как карбонат или бикарбонат натрия или кальция, которое покрывает кристаллы после измельчения. Смесь затем прессуют до образования таблетки, которая имеет улучшенный профиль растворимости активного с медицинской точки зрения ингредиента.
EA201171399A 2009-05-11 2010-05-10 Способ и композиция для улучшения всасывания лекарственных средств EA201171399A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/387,977 US11135188B2 (en) 2009-05-11 2009-05-11 Method and composition to improve absorption of therapeutic agents
PCT/US2010/001375 WO2010132095A1 (en) 2009-05-11 2010-05-10 Method and composition to improve absorption of therapeutic agents

Publications (1)

Publication Number Publication Date
EA201171399A1 true EA201171399A1 (ru) 2012-05-30

Family

ID=43062708

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201171399A EA201171399A1 (ru) 2009-05-11 2010-05-10 Способ и композиция для улучшения всасывания лекарственных средств

Country Status (15)

Country Link
US (1) US11135188B2 (ru)
EP (1) EP2429502B1 (ru)
AR (1) AR076864A1 (ru)
BR (1) BRPI1013509A2 (ru)
CA (1) CA2761678A1 (ru)
CL (1) CL2011002807A1 (ru)
CO (1) CO6460753A2 (ru)
EA (1) EA201171399A1 (ru)
HU (1) HUE043173T2 (ru)
MX (1) MX2011011928A (ru)
PL (1) PL2429502T3 (ru)
PT (1) PT2429502T (ru)
SI (1) SI2429502T1 (ru)
UY (1) UY32624A (ru)
WO (1) WO2010132095A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11135188B2 (en) 2009-05-11 2021-10-05 Bayer Healthcare Llc Method and composition to improve absorption of therapeutic agents
WO2014122195A1 (en) * 2013-02-06 2014-08-14 Hermes Arzneimittel Gmbh Pharmaceutical compositions incorporating low-dose drugs
US10195153B2 (en) 2013-08-12 2019-02-05 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
PT3154528T (pt) 2014-06-11 2023-06-22 SpecGx LLC Composições secas por pulverização possuindo diferentes perfis de dissolução e processos para a sua preparação
CA2955229C (en) 2014-07-17 2020-03-10 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
EP3209282A4 (en) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
US11197830B2 (en) * 2019-02-27 2021-12-14 Aft Pharmaceuticals Limited Pharmaceutical composition containing acetaminophen and ibuprofen
MX2023005639A (es) * 2020-11-13 2023-09-22 Bayer Healthcare Llc Comprimidos de capa doble orales que comprenden acido acetilsalicilico y pseudoefedrina, metodos para preparar y utilizar los mismos.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB191225486A (en) 1912-11-06 1913-04-24 Herbert Sefton-Jones Manufacture and Production of Improved Pharmaceutical Preparations.
US2293359A (en) 1941-01-08 1942-08-18 Quisling Sverre Acetyl salicylic acid preparation
FI89004C (fi) 1988-02-16 1993-08-10 Pertti J Neuvonen Anvaendning av tillsatsmedel foer oekning av absorptionshastigheten av laekemedel i orala laekemedelspreparat
RU2099058C1 (ru) 1992-06-15 1997-12-20 Институт химии твердого тела и переработки минерального сырья СО РАН Способ получения твердой быстрорастворимой дисперсной системы, содержащей ацетилсалициловую кислоту
US5665388A (en) 1995-11-13 1997-09-09 Health Corporation Method for preparation of an alkaline and aspirin combination compound
ZA987800B (en) 1997-08-27 1999-06-09 Hexal Ag Pharmaceutical composition of meloxicam
US8231899B2 (en) * 1998-09-10 2012-07-31 Nycomed Danmark Aps Quick release pharmaceutical compositions of drug substances
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
RU2170582C1 (ru) 2000-02-17 2001-07-20 Институт химии твердого тела и механохимии СО РАН Способ получения быстрорастворимой таблетированной формы ацетилсалициловой кислоты
WO2005105102A1 (en) 2004-05-04 2005-11-10 Equitech Corporation Improved nsaid composition
US8216610B2 (en) 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
GEP20094671B (en) * 2004-06-29 2009-04-27 Nycomed Danmark Aps Manufacturing of quick release pharmaceutical compositions of water insoluble drugs and pharmaceutical compositions obtained by the process of the invention
ES2409347T3 (es) * 2004-10-21 2013-06-26 Aptalis Pharmatech, Inc. Composiciones farmacéuticas de sabor enmascarado con agentes porogénicos gastrosolubles
CA2629904C (en) 2005-11-28 2018-07-10 Imaginot Pty Ltd. Oral therapeutic compound delivery system
US11135188B2 (en) 2009-05-11 2021-10-05 Bayer Healthcare Llc Method and composition to improve absorption of therapeutic agents

Also Published As

Publication number Publication date
PL2429502T3 (pl) 2019-07-31
UY32624A (es) 2010-12-31
PT2429502T (pt) 2019-03-29
US20100286100A1 (en) 2010-11-11
CA2761678A1 (en) 2010-11-18
SI2429502T1 (sl) 2019-05-31
CO6460753A2 (es) 2012-06-15
MX2011011928A (es) 2011-12-06
WO2010132095A1 (en) 2010-11-18
EP2429502A4 (en) 2012-10-24
EP2429502A1 (en) 2012-03-21
US11135188B2 (en) 2021-10-05
WO2010132095A8 (en) 2011-07-07
BRPI1013509A2 (pt) 2016-04-05
CL2011002807A1 (es) 2012-06-15
AR076864A1 (es) 2011-07-13
EP2429502B1 (en) 2018-12-26
HUE043173T2 (hu) 2019-08-28

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