IN2014CN02982A - - Google Patents
Info
- Publication number
- IN2014CN02982A IN2014CN02982A IN2982CHN2014A IN2014CN02982A IN 2014CN02982 A IN2014CN02982 A IN 2014CN02982A IN 2982CHN2014 A IN2982CHN2014 A IN 2982CHN2014A IN 2014CN02982 A IN2014CN02982 A IN 2014CN02982A
- Authority
- IN
- India
- Prior art keywords
- glycosylated
- interferon
- activity
- glycosylated polypeptide
- carbohydrate structure
- Prior art date
Links
- 102000007079 Peptide Fragments Human genes 0.000 abstract 4
- 108010033276 Peptide Fragments Proteins 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 102000003996 Interferon-beta Human genes 0.000 abstract 2
- 108090000467 Interferon-beta Proteins 0.000 abstract 2
- 125000000837 carbohydrate group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229960001388 interferon-beta Drugs 0.000 abstract 2
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011218793 | 2011-10-01 | ||
| PCT/JP2012/075262 WO2013047846A1 (ja) | 2011-10-01 | 2012-09-28 | 糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02982A true IN2014CN02982A (https=) | 2015-07-03 |
Family
ID=47995870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2982CHN2014 IN2014CN02982A (https=) | 2011-10-01 | 2012-09-28 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10358470B2 (https=) |
| EP (1) | EP2762489B1 (https=) |
| JP (1) | JP6153470B2 (https=) |
| KR (1) | KR101979045B1 (https=) |
| CN (2) | CN109134642A (https=) |
| AU (1) | AU2012317325B2 (https=) |
| BR (1) | BR112014007766B1 (https=) |
| CA (1) | CA2850469C (https=) |
| DK (1) | DK2762489T3 (https=) |
| IN (1) | IN2014CN02982A (https=) |
| MY (1) | MY168902A (https=) |
| PH (1) | PH12014500694B1 (https=) |
| RU (1) | RU2636456C2 (https=) |
| SG (2) | SG11201401071YA (https=) |
| TW (1) | TWI633115B (https=) |
| WO (1) | WO2013047846A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2762489T3 (en) | 2011-10-01 | 2018-07-02 | Glytech Inc | GLYCOSYLED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME |
| SG11201507769SA (en) * | 2013-03-29 | 2015-10-29 | Glytech Inc | Polypeptide having sialylated sugar chains attached thereto |
| CN114685645B (zh) * | 2020-12-30 | 2025-03-21 | 深圳翰宇药业股份有限公司 | 一种索玛鲁肽的合成方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0237019A3 (en) | 1986-03-14 | 1988-03-09 | Toray Industries, Inc. | Interferon conjugate and production thereof using recombinant gene |
| JP2001507215A (ja) | 1997-01-16 | 2001-06-05 | サイテル コーポレイション | 組換え糖タンパク質のインビトロでの実用的なシアリル化 |
| DE19717864C2 (de) | 1997-04-23 | 2001-05-17 | Fraunhofer Ges Forschung | Humanes rekombinantes Interferon-beta, Verfahren zu seiner Herstellung und seine Verwendung |
| EE05214B1 (et) * | 1998-04-28 | 2009-10-15 | Applied Research Systems ARS Holding N.V. | Polool-IFN- β konjugaat, selle valmistamismeetod ja farmatseutiline kompositsioon |
| HU229888B1 (en) | 1998-10-16 | 2014-11-28 | Biogen Idec Ma Inc Cambridge | Polymer conjugates of interferon betha-1a and uses |
| BR9915548A (pt) * | 1998-10-16 | 2001-08-14 | Biogen Inc | Proteìnas de fusão de interferon-beta e usos |
| US6514729B1 (en) * | 1999-05-12 | 2003-02-04 | Xencor, Inc. | Recombinant interferon-beta muteins |
| EP1240327B1 (en) * | 1999-12-08 | 2008-02-06 | Amgen Inc., | Interferon-like molecules and uses thereof |
| US7795002B2 (en) | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| KR20030057529A (ko) | 2000-09-08 | 2003-07-04 | 그리폰 테라퓨틱스, 인코포레이티드 | 합성 적혈구생성 자극 단백질 |
| WO2002074806A2 (en) | 2001-02-27 | 2002-09-26 | Maxygen Aps | New interferon beta-like molecules |
| BR0208041A (pt) | 2001-03-15 | 2004-02-25 | Merck Patent Gmbh | Interferon beta modificado com imunogenicidade reduzida |
| US7226903B2 (en) * | 2001-10-10 | 2007-06-05 | Neose Technologies, Inc. | Interferon beta: remodeling and glycoconjugation of interferon beta |
| ES2411007T3 (es) * | 2001-10-10 | 2013-07-04 | Novo Nordisk A/S | Remodelación y glicoconjugación de péptidos |
| AU2002358181A1 (en) | 2001-12-11 | 2003-07-09 | Aventis Pasteur | Mutated hiv tat |
| US20060083715A1 (en) * | 2002-03-12 | 2006-04-20 | Steven Glazer | Interferon beta-like molecules for treatment of stroke |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| AU2003254641A1 (en) | 2002-08-28 | 2004-03-19 | Maxygen Aps | Interferon beta-like molecules for treatment of cancer |
| JP2006513990A (ja) * | 2002-09-27 | 2006-04-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | インターフェロンβを用いる慢性炎症性脱髄性多発性ニューロパシーの治療 |
| EP1581631A4 (en) | 2002-10-01 | 2007-09-05 | Xencor Inc | INTERFERON VARIANTS HAVING IMPROVED PROPERTIES |
| KR100876518B1 (ko) | 2002-12-26 | 2008-12-31 | 오츠카 가가쿠 가부시키가이샤 | 당사슬 아스파라긴 유도체 및 그의 제조방법 |
| AU2004266969B2 (en) | 2003-08-25 | 2010-02-25 | Taniguchi, Tadatsugu | Interferon-beta composite |
| US20090214472A1 (en) | 2004-03-01 | 2009-08-27 | Enzon Pharmaceuticals Inc. | Interferon-beta polymer conjugates |
| RU2392963C2 (ru) * | 2004-08-09 | 2010-06-27 | Элиоз Байофарма, Инк. | Синтетические варианты гипергликозилированного протеазо-резистентного полипептида, пероральные композиции и способы применения таких вариантов |
| WO2006020580A2 (en) | 2004-08-09 | 2006-02-23 | Alios Biopharma Inc. | Synthetic hyperglycosylated, protease-resistant polypeptide variants, oral formulations and methods of using the same |
| KR100781666B1 (ko) | 2004-11-02 | 2007-12-03 | 신영기 | 인간 인터페론-베타 변이체 |
| WO2007022799A1 (en) * | 2005-08-26 | 2007-03-01 | Ares Trading S.A. | Process for the preparation of glycosylated interferon beta |
| US20080038224A1 (en) * | 2006-03-28 | 2008-02-14 | Thierry Guyon | Modified interferon-beta (IFN-beta) polypeptides |
| US20080096819A1 (en) | 2006-05-02 | 2008-04-24 | Allozyne, Inc. | Amino acid substituted molecules |
| KR20100049032A (ko) * | 2007-06-19 | 2010-05-11 | 오츠카 가가쿠 가부시키가이샤 | 당사슬 부가 ｇｌｐ―１ 펩티드 |
| CA2694542C (en) | 2007-07-31 | 2017-08-29 | Otsuka Chemical Co., Ltd. | Method for producing peptide |
| JP2009242372A (ja) | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| US8765669B2 (en) | 2008-06-17 | 2014-07-01 | Glytech, Inc. | Glycosylated GLP-1 peptide |
| CA2733362C (en) * | 2008-08-08 | 2016-10-18 | Universiteit Gent | Cells producing glycoproteins having altered glycosylation patterns and methods and use thereof |
| HUE037238T2 (hu) * | 2008-08-19 | 2018-08-28 | Glytech Inc | Glikoprotein elõállítási eljárás és screening eljárás |
| WO2012051615A1 (en) | 2010-10-15 | 2012-04-19 | Transgenrx, Inc. | Novel vectors for production of glycosylated interferon |
| RU2586524C2 (ru) | 2011-03-10 | 2016-06-10 | Глитек, Инк. | Способ получения гликопептида, имеющего сиалированную сахарную цепь, и способ получения производного сиалилгликоаспарагина |
| WO2013002330A1 (ja) | 2011-06-29 | 2013-01-03 | 協和発酵キリン株式会社 | たん白質の精製方法 |
| DK2762489T3 (en) | 2011-10-01 | 2018-07-02 | Glytech Inc | GLYCOSYLED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME |
-
2012
- 2012-09-28 DK DK12836998.0T patent/DK2762489T3/en active
- 2012-09-28 SG SG11201401071YA patent/SG11201401071YA/en unknown
- 2012-09-28 US US14/347,222 patent/US10358470B2/en active Active
- 2012-09-28 AU AU2012317325A patent/AU2012317325B2/en not_active Ceased
- 2012-09-28 PH PH1/2014/500694A patent/PH12014500694B1/en unknown
- 2012-09-28 EP EP12836998.0A patent/EP2762489B1/en active Active
- 2012-09-28 JP JP2013536471A patent/JP6153470B2/ja not_active Expired - Fee Related
- 2012-09-28 MY MYPI2014000925A patent/MY168902A/en unknown
- 2012-09-28 BR BR112014007766-5A patent/BR112014007766B1/pt not_active IP Right Cessation
- 2012-09-28 WO PCT/JP2012/075262 patent/WO2013047846A1/ja not_active Ceased
- 2012-09-28 KR KR1020147010631A patent/KR101979045B1/ko not_active Expired - Fee Related
- 2012-09-28 CN CN201811042210.1A patent/CN109134642A/zh active Pending
- 2012-09-28 CA CA2850469A patent/CA2850469C/en active Active
- 2012-09-28 SG SG10201602076QA patent/SG10201602076QA/en unknown
- 2012-09-28 RU RU2014116550A patent/RU2636456C2/ru active
- 2012-09-28 CN CN201280058952.8A patent/CN104080803B/zh not_active Expired - Fee Related
- 2012-09-28 IN IN2982CHN2014 patent/IN2014CN02982A/en unknown
- 2012-10-01 TW TW101136177A patent/TWI633115B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2850469A1 (en) | 2013-04-04 |
| DK2762489T3 (en) | 2018-07-02 |
| TW201321404A (zh) | 2013-06-01 |
| SG11201401071YA (en) | 2014-08-28 |
| CN104080803A (zh) | 2014-10-01 |
| TWI633115B (zh) | 2018-08-21 |
| AU2012317325B2 (en) | 2016-10-06 |
| AU2012317325A1 (en) | 2014-04-17 |
| BR112014007766A2 (pt) | 2017-04-04 |
| EP2762489B1 (en) | 2018-03-28 |
| SG10201602076QA (en) | 2016-04-28 |
| CA2850469C (en) | 2020-07-07 |
| PH12014500694A1 (en) | 2014-05-12 |
| MY168902A (en) | 2018-12-04 |
| EP2762489A9 (en) | 2015-02-11 |
| KR101979045B1 (ko) | 2019-05-15 |
| PH12014500694B1 (en) | 2020-01-31 |
| RU2636456C2 (ru) | 2017-11-23 |
| EP2762489A1 (en) | 2014-08-06 |
| WO2013047846A1 (ja) | 2013-04-04 |
| CN104080803B (zh) | 2020-08-04 |
| US20140369964A1 (en) | 2014-12-18 |
| KR20140095051A (ko) | 2014-07-31 |
| JPWO2013047846A1 (ja) | 2015-03-30 |
| RU2014116550A (ru) | 2015-10-27 |
| US10358470B2 (en) | 2019-07-23 |
| JP6153470B2 (ja) | 2017-06-28 |
| EP2762489A4 (en) | 2015-05-06 |
| BR112014007766B1 (pt) | 2022-05-10 |
| CN109134642A (zh) | 2019-01-04 |
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