SG10201602076QA - Glycosylated polypeptide and pharmaceutical composition containing same - Google Patents

Glycosylated polypeptide and pharmaceutical composition containing same

Info

Publication number
SG10201602076QA
SG10201602076QA SG10201602076QA SG10201602076QA SG10201602076QA SG 10201602076Q A SG10201602076Q A SG 10201602076QA SG 10201602076Q A SG10201602076Q A SG 10201602076QA SG 10201602076Q A SG10201602076Q A SG 10201602076QA SG 10201602076Q A SG10201602076Q A SG 10201602076QA
Authority
SG
Singapore
Prior art keywords
pharmaceutical composition
composition containing
containing same
glycosylated polypeptide
glycosylated
Prior art date
Application number
SG10201602076QA
Inventor
Izumi Sakamoto
Kazuhiro Fukae
Katsunari Tezuka
Keisuke Tazuru
Masatoshi Maeda
Yasuhiro Kajihara
Takashi Tsuji
Original Assignee
Glytech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glytech Inc filed Critical Glytech Inc
Publication of SG10201602076QA publication Critical patent/SG10201602076QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/026General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10201602076QA 2011-10-01 2012-09-28 Glycosylated polypeptide and pharmaceutical composition containing same SG10201602076QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011218793 2011-10-01

Publications (1)

Publication Number Publication Date
SG10201602076QA true SG10201602076QA (en) 2016-04-28

Family

ID=47995870

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201602076QA SG10201602076QA (en) 2011-10-01 2012-09-28 Glycosylated polypeptide and pharmaceutical composition containing same
SG11201401071YA SG11201401071YA (en) 2011-10-01 2012-09-28 Glycosylated polypeptide and pharmaceutical composition containing same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201401071YA SG11201401071YA (en) 2011-10-01 2012-09-28 Glycosylated polypeptide and pharmaceutical composition containing same

Country Status (15)

Country Link
US (1) US10358470B2 (en)
EP (1) EP2762489B1 (en)
JP (1) JP6153470B2 (en)
KR (1) KR101979045B1 (en)
CN (2) CN104080803B (en)
AU (1) AU2012317325B2 (en)
BR (1) BR112014007766B1 (en)
CA (1) CA2850469C (en)
DK (1) DK2762489T3 (en)
IN (1) IN2014CN02982A (en)
MY (1) MY168902A (en)
RU (1) RU2636456C2 (en)
SG (2) SG10201602076QA (en)
TW (1) TWI633115B (en)
WO (1) WO2013047846A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10358470B2 (en) 2011-10-01 2019-07-23 Glytech, Inc. Glycosylated polypeptide and pharmaceutical composition containing same
MY171183A (en) 2013-03-29 2019-09-30 Glytech Inc Polypeptide glycosylated with sialylated sugar chain
CN114685645A (en) * 2020-12-30 2022-07-01 深圳翰宇药业股份有限公司 Synthetic method of somaglutide

Family Cites Families (39)

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EP0237019A3 (en) * 1986-03-14 1988-03-09 Toray Industries, Inc. Interferon conjugate and production thereof using recombinant gene
IL130964A0 (en) 1997-01-16 2001-01-28 Cytel Corp Practical in vitro sialylation of recombinant glycoproteins
DE19717864C2 (en) 1997-04-23 2001-05-17 Fraunhofer Ges Forschung Human recombinant interferon beta, process for its preparation and its use
CN1187094C (en) * 1998-04-28 2005-02-02 应用研究系统Ars股份公司 Polyol-IFN-beta conjugates
AU762616B2 (en) 1998-10-16 2003-07-03 Biogen Ma Inc. Polymer conjugates of interferon beta-1a and uses
PL200586B1 (en) * 1998-10-16 2009-01-30 Biogen Idec Inc Polypeptides containing interferon-beta-1a mutants, their encoding nucleic acid molecules, host cells transformed by these molecules, method for the manufacture of polypeptides, polypeptides containing pharmaceutical compounds and polypeptide applications
US6514729B1 (en) 1999-05-12 2003-02-04 Xencor, Inc. Recombinant interferon-beta muteins
ATE385517T1 (en) * 1999-12-08 2008-02-15 Amgen Inc INTERFERON-LIKE MOLECULES AND USES THEREOF
US7795002B2 (en) * 2000-06-28 2010-09-14 Glycofi, Inc. Production of galactosylated glycoproteins in lower eukaryotes
AU2001273385B2 (en) 2000-09-08 2005-04-07 Gryphon Therapeutics, Inc. Polymer-modified synthetic proteins
MXPA03007619A (en) 2001-02-27 2003-12-04 Maxygen Aps New interferon beta-like molecules.
MXPA03008310A (en) 2001-03-15 2003-12-11 Merck Patent Gmbh Modified interferon beta with reduced immunogenicity.
EP2292271A3 (en) * 2001-10-10 2011-09-14 BioGeneriX AG Remodelling and glycoconjugation of an antibody
US7226903B2 (en) 2001-10-10 2007-06-05 Neose Technologies, Inc. Interferon beta: remodeling and glycoconjugation of interferon beta
WO2003054006A2 (en) 2001-12-11 2003-07-03 Aventis Pasteur Mutated hiv tat
CA2477577A1 (en) 2002-03-12 2003-09-18 Maxygen Aps Interferon beta-like molecules for treatment of stroke
US7943763B2 (en) 2002-07-05 2011-05-17 Otsuka Chemical Holdings Co., Ltd. Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides
WO2004020468A2 (en) 2002-08-28 2004-03-11 Maxygen Aps Interferon beta-like molecules for treatment of cancer
RS20050255A (en) * 2002-09-27 2007-08-03 Biogen Idec Ma Inc., Therapies for chronic inflammatory demyelinating polyneuropathy using interferon-betha
CA2500626A1 (en) 2002-10-01 2004-04-15 Xencor, Inc. Interferon variants with improved properties
JP4495598B2 (en) 2002-12-26 2010-07-07 康宏 梶原 Sugar chain asparagine derivative and method for producing the same
JP4850514B2 (en) 2003-08-25 2012-01-11 東レ株式会社 Interferon β complex
WO2005084303A2 (en) 2004-03-01 2005-09-15 Enzon Pharmaceuticals, Inc. Interferon-beta polymer conjugates
RU2392963C2 (en) * 2004-08-09 2010-06-27 Элиоз Байофарма, Инк. Synthetic versions of hyperglycolised protease-resistive polypeptide, oral compositions and methods of using such versions
EP1789074A4 (en) 2004-08-09 2009-08-12 Alios Biopharma Inc Synthetic hyperglycosylated, protease-resistant polypeptide variants, oral formulations and methods of using the same
KR100781666B1 (en) 2004-11-02 2007-12-03 신영기 Human Interferon-beta Mutein
EP1917276B1 (en) * 2005-08-26 2018-03-21 Ares Trading S.A. Process for the preparation of glycosylated interferon beta
US20080003202A1 (en) * 2006-03-28 2008-01-03 Thierry Guyon Modified interferon-beta (IFN-beta) polypeptides
US20080096819A1 (en) 2006-05-02 2008-04-24 Allozyne, Inc. Amino acid substituted molecules
RU2539829C2 (en) * 2007-06-19 2015-01-27 ГЛИТЕК,ИНК.,Япония Glp-1 peptide having attached oligosaccharide chain
DK2184290T3 (en) * 2007-07-31 2015-05-26 Glytech Inc PROCEDURE FOR PEPTID PREPARATION
JP2009242372A (en) 2008-03-11 2009-10-22 Yokohama City Univ Erythropoietin derivative having uniform sugar chain structure
RU2543157C2 (en) 2008-06-17 2015-02-27 Глитек,Инк. Glycated peptide glp-1
US8815580B2 (en) * 2008-08-08 2014-08-26 Vib Vzw Cells producing glycoproteins having altered glycosylation patterns and method and use thereof
US20110262945A1 (en) * 2008-08-19 2011-10-27 Otsuka Chemical Co., Ltd. Glycoprotein production method and screening method
WO2012051615A1 (en) 2010-10-15 2012-04-19 Transgenrx, Inc. Novel vectors for production of glycosylated interferon
EP2684899B1 (en) 2011-03-10 2018-04-25 Glytech, Inc. Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide
JP6151640B2 (en) 2011-06-29 2017-06-21 協和発酵キリン株式会社 Protein purification method
US10358470B2 (en) 2011-10-01 2019-07-23 Glytech, Inc. Glycosylated polypeptide and pharmaceutical composition containing same

Also Published As

Publication number Publication date
JP6153470B2 (en) 2017-06-28
EP2762489A1 (en) 2014-08-06
AU2012317325B2 (en) 2016-10-06
CN109134642A (en) 2019-01-04
TW201321404A (en) 2013-06-01
EP2762489A9 (en) 2015-02-11
KR101979045B1 (en) 2019-05-15
EP2762489A4 (en) 2015-05-06
BR112014007766A2 (en) 2017-04-04
CN104080803B (en) 2020-08-04
CA2850469A1 (en) 2013-04-04
IN2014CN02982A (en) 2015-07-03
CA2850469C (en) 2020-07-07
EP2762489B1 (en) 2018-03-28
KR20140095051A (en) 2014-07-31
US20140369964A1 (en) 2014-12-18
WO2013047846A1 (en) 2013-04-04
RU2014116550A (en) 2015-10-27
RU2636456C2 (en) 2017-11-23
MY168902A (en) 2018-12-04
AU2012317325A1 (en) 2014-04-17
JPWO2013047846A1 (en) 2015-03-30
TWI633115B (en) 2018-08-21
US10358470B2 (en) 2019-07-23
DK2762489T3 (en) 2018-07-02
BR112014007766B1 (en) 2022-05-10
CN104080803A (en) 2014-10-01
SG11201401071YA (en) 2014-08-28

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