IN2014CN02163A - - Google Patents

Info

Publication number
IN2014CN02163A
IN2014CN02163A IN2163CHN2014A IN2014CN02163A IN 2014CN02163 A IN2014CN02163 A IN 2014CN02163A IN 2163CHN2014 A IN2163CHN2014 A IN 2163CHN2014A IN 2014CN02163 A IN2014CN02163 A IN 2014CN02163A
Authority
IN
India
Prior art keywords
endos49
igg
mutant
endos
seq
Prior art date
Application number
Other languages
English (en)
Inventor
Mattias Collin
Maria Allhorn
Jonathan Sjögren
Original Assignee
Genovis Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genovis Ab filed Critical Genovis Ab
Publication of IN2014CN02163A publication Critical patent/IN2014CN02163A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01096Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (3.2.1.96)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN2163CHN2014 2011-09-13 2012-09-12 IN2014CN02163A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201115841A GB201115841D0 (en) 2011-09-13 2011-09-13 Protein and method
PCT/EP2012/067841 WO2013037824A1 (en) 2011-09-13 2012-09-12 Endoglycosidase from streptococcus pyogenes and methods using it

Publications (1)

Publication Number Publication Date
IN2014CN02163A true IN2014CN02163A (ko) 2015-05-29

Family

ID=44908522

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2163CHN2014 IN2014CN02163A (ko) 2011-09-13 2012-09-12

Country Status (20)

Country Link
US (1) US9493752B2 (ko)
EP (1) EP2756077B1 (ko)
JP (1) JP6076349B2 (ko)
KR (1) KR102001427B1 (ko)
CN (1) CN103946377B (ko)
AU (1) AU2012307461B2 (ko)
BR (1) BR112014005816A2 (ko)
CA (1) CA2848230C (ko)
DK (1) DK2756077T3 (ko)
EA (1) EA028490B8 (ko)
ES (1) ES2627334T3 (ko)
GB (2) GB201115841D0 (ko)
IL (1) IL231410A0 (ko)
IN (1) IN2014CN02163A (ko)
MX (1) MX347727B (ko)
PL (1) PL2756077T3 (ko)
PT (1) PT2756077T (ko)
SG (1) SG11201400505YA (ko)
WO (1) WO2013037824A1 (ko)
ZA (1) ZA201401840B (ko)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002050107A2 (en) * 2000-12-21 2002-06-27 Shire Biochem Inc. Streptococcus pyogenes antigens and corresponding dna fragments
PT2911699T (pt) 2012-10-23 2018-02-23 Synaffix Bv Anticorpo modificado, anticorpo conjugado e seu processo de preparação
DK2991683T3 (da) * 2013-05-02 2019-11-04 Glykos Finland Oy Konjugater af et glykoprotein eller en glykan med en toksisk ladning
JP2016538878A (ja) 2013-10-14 2016-12-15 シンアフィックス ビー.ブイ. 糖鎖工学的に操作された抗体、抗体コンジュゲート、及びそれらの調製方法
JP2016538877A (ja) 2013-10-14 2016-12-15 シンアフィックス ビー.ブイ. 修飾糖タンパク質、タンパク質コンジュゲート及びそれらの調製方法
WO2015057064A1 (en) 2013-10-14 2015-04-23 Synaffix B.V. Modified glycoprotein, protein-conjugate and process for the preparation thereof
US20160235861A1 (en) 2013-10-14 2016-08-18 SynAffix. B.V. Glycoengineered antibody, antibody-conjugate and methods for their preparation
GB201318490D0 (en) * 2013-10-18 2013-12-04 Genovis Ab Method
US11168085B2 (en) 2014-01-24 2021-11-09 Synaffix B.V. Process for the cycloaddition of a hetero(aryl) 1,3-dipole compound with a (hetero)cycloalkyne
EP3682904A1 (en) 2014-06-30 2020-07-22 Glykos Finland Oy Saccharide derivative of a toxic payload and antibody conjugates thereof
GB201413240D0 (en) * 2014-07-25 2014-09-10 Hansa Medical Ab Method
KR20170030648A (ko) 2014-08-04 2017-03-17 시나픽스 비.브이. 베타-(1,4)-n-아세틸갈락토오스아미닐트랜스퍼라아제, 또는 이의 돌연변이체를 이용한 당 단백질의 변형 방법
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502305D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
PL3134520T3 (pl) 2015-04-23 2018-06-29 Synaffix B.V. Sposób modyfikacji glikoproteiny z zastosowaniem glikozylotransferazy, która jest lub pochodzi od β-(1,4)-N-acetylogalaktozaminylotransferazy
EP3402815B1 (en) 2016-01-15 2023-12-06 University of Maryland, College Park Endo-s2 mutants as glycosynthases, method of making and use for glycoengineering of glycoproteins
KR20180124857A (ko) 2016-02-04 2018-11-21 게노비스 에이비 신규한 스트렙토코커스 프로테아제
TWI727884B (zh) * 2016-08-24 2021-05-11 醣基生醫股份有限公司 利用醣苷內切酶突變體重塑醣蛋白及其使用方法
CN111183221B (zh) 2017-05-26 2024-04-09 杰诺维斯公司 用于o-糖蛋白的蛋白酶和结合多肽
US20210228738A1 (en) 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
JP2021528406A (ja) 2018-06-19 2021-10-21 グリコス バイオメディカル オーワイ コンジュゲート
US20210138080A1 (en) 2018-06-29 2021-05-13 Glykos Biomedical Oy Conjugates
US20230038373A1 (en) 2019-12-18 2023-02-09 Glykos Biomedical Oy Stabile conjugate
CN111044731B (zh) * 2019-12-19 2021-05-07 北京科技大学 脉冲温育免疫反应分离富集多肽药物中肽类杂质的方法
IL294321A (en) 2020-01-09 2022-08-01 Mersana Therapeutics Inc Antibody-drug conjugates are attached at a specific site with linkers that include peptides
WO2022057942A1 (zh) * 2020-09-21 2022-03-24 上海宝济药业有限公司 一种药物组合及其应用
US11964024B2 (en) 2021-01-04 2024-04-23 Mersana Therapeutics, Inc. B7H4-targeted antibody-drug conjugates and methods of use thereof
EP4079848A1 (en) 2021-04-22 2022-10-26 Genovis Ab Immunoglobulin cleaving enzyme
CN115873833A (zh) * 2022-11-08 2023-03-31 上海泰昶生物技术有限公司 生产免疫球蛋白g降解酶的工程菌株和工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130228D0 (en) 2001-12-18 2002-02-06 Hansa Medica Ab Protein
GB0624874D0 (en) * 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
WO2009033670A2 (en) * 2007-09-14 2009-03-19 Genovis Ab Method and kits for dissociating fcgamma-receptor-igg complexes and for igg purification and detection
GB0821100D0 (en) 2008-11-18 2008-12-24 Hansa Medical Ab Antibodies
EP2483693B1 (en) * 2009-10-02 2014-12-03 Roche Glycart AG A-fucosylation detection in antibodies

Also Published As

Publication number Publication date
GB2509284A (en) 2014-06-25
JP6076349B2 (ja) 2017-02-08
EP2756077A1 (en) 2014-07-23
SG11201400505YA (en) 2014-04-28
EA028490B1 (ru) 2017-11-30
JP2014531205A (ja) 2014-11-27
CA2848230A1 (en) 2013-03-21
AU2012307461A1 (en) 2014-03-27
CA2848230C (en) 2020-03-24
NZ622172A (en) 2016-04-29
CN103946377A (zh) 2014-07-23
IL231410A0 (en) 2014-04-30
EA201490447A1 (ru) 2014-09-30
CN103946377B (zh) 2016-10-05
KR102001427B1 (ko) 2019-07-18
EA028490B8 (ru) 2018-01-31
PT2756077T (pt) 2017-06-21
AU2012307461B2 (en) 2016-08-18
WO2013037824A1 (en) 2013-03-21
KR20140081813A (ko) 2014-07-01
US20140302519A1 (en) 2014-10-09
DK2756077T3 (en) 2017-07-03
PL2756077T3 (pl) 2017-09-29
MX2014002906A (es) 2014-10-17
BR112014005816A2 (pt) 2020-12-29
ZA201401840B (en) 2018-05-30
MX347727B (es) 2017-05-10
US9493752B2 (en) 2016-11-15
EP2756077B1 (en) 2017-03-29
GB201406321D0 (en) 2014-05-21
GB201115841D0 (en) 2011-10-26
ES2627334T3 (es) 2017-07-27

Similar Documents

Publication Publication Date Title
IN2014CN02163A (ko)
NZ702962A (en) Agse-deficient strain
PH12017500785A1 (en) INTERFERON a2B VARIANTS
WO2012125937A3 (en) Glycosyl hydrolase enzymes and uses thereof for biomass hydrolysis
IN2014CN01614A (ko)
MX2015000844A (es) Cepa con deficit de amilasa.
PH12016500377A1 (en) Polypeptide for the hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof, and additive containing polypeptide, use of said polypeptide and method
MX2009005655A (es) Composiciones y usos de un polipeptido alfa-amilasa del bacilo de la especie 195.
NZ616035A (en) Compositions relating to a mutant clostridium difficile toxin and methods thereof
NZ725398A (en) Variants of chymosin with improved milk-clotting properties
MX346373B (es) Metodo para preparar harina de grano entero altamente dispersable con un contenido mejorado de avenantramida.
MY171544A (en) A cell with reduced ppgppase activity
WO2012087676A3 (en) Production of fatty acids and fatty acid derivatives by recombinant microorganisms
EA201300876A1 (ru) Мутантная целлобиогидролаза
NZ731727A (en) Method for producing a protein hydrolysate
WO2010101359A3 (ko) L-아미노산 생산 미생물 및 이를 이용한 l-아미노산 생산 방법
MX2019007032A (es) Operaciones de cosecha mejoradas para proteinas recombinadas.
MY159439A (en) Method for producing glucosidase, enzyme composition, and method for hydrolyzing biomass
AU2015344324A8 (en) Endoxylanase mutant, enzyme composition for biomass decomposition, and method for producing sugar solution
MX2012000532A (es) Procesamiento de anticuerpo enzimatico.
NZ707753A (en) Purification of recombinant human galactocerebroside β-galactosidase (rhgalc)
EA033091B1 (ru) ПШЕНИЦА С НОВЫМИ АЛЛЕЛЯМИ Rht-B1
WO2009129086A3 (en) Endoglycosidases that cleave o-linked glycans
WO2011124925A3 (en) Polysaccharide degrading enzymes from coleoptera
IN2015DN01766A (ko)