IN2012DN01850A - - Google Patents
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- Publication number
- IN2012DN01850A IN2012DN01850A IN1850DEN2012A IN2012DN01850A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A IN 1850DEN2012 A IN1850DEN2012 A IN 1850DEN2012A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A
- Authority
- IN
- India
- Prior art keywords
- separation
- line
- units
- fluid
- separation unit
- Prior art date
Links
- 238000000926 separation method Methods 0.000 abstract 11
- 239000012530 fluid Substances 0.000 abstract 4
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/566,701 US9527010B2 (en) | 2009-09-25 | 2009-09-25 | Separation system and method |
| PCT/SE2010/051003 WO2011037522A1 (en) | 2009-09-25 | 2010-09-20 | Separation system and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN01850A true IN2012DN01850A (enExample) | 2015-08-21 |
Family
ID=43779133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1850DEN2012 IN2012DN01850A (enExample) | 2009-09-25 | 2010-09-20 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9527010B2 (enExample) |
| EP (1) | EP2480305B1 (enExample) |
| JP (1) | JP5749270B2 (enExample) |
| CN (1) | CN102574026B (enExample) |
| AU (1) | AU2010298768B2 (enExample) |
| IN (1) | IN2012DN01850A (enExample) |
| WO (1) | WO2011037522A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5961112B2 (ja) * | 2009-09-25 | 2016-08-02 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 液体混合物の調製方法及びシステム |
| CA2787897A1 (en) * | 2010-02-12 | 2011-08-18 | Dsm Ip Assets B.V. | Single unit antibody purification |
| EP2598515B1 (en) * | 2010-07-30 | 2016-09-21 | Pfizer Inc | Tandem purification of proteins |
| EP2433952B1 (en) * | 2010-09-20 | 2015-09-02 | Asahi Kasei Bioprocess, Inc. | Liquid chromatography system and method for protein separation and purification |
| JP2013540787A (ja) * | 2010-11-01 | 2013-11-07 | ディーエスエム アイピー アセッツ ビー.ブイ. | 単一ユニットイオン交換クロマトグラフィー抗体精製 |
| BR112013031906A2 (pt) * | 2011-06-16 | 2016-12-13 | Dsm Ip Assets Bv | unidade única de cromatografia de purificação de anticorpo |
| WO2013028330A2 (en) * | 2011-08-19 | 2013-02-28 | Emd Millipore Corporation | Methods of reducing level of one of more impurities in a sample during protein purification |
| EP2578286A1 (en) | 2011-10-04 | 2013-04-10 | Merck Patent GmbH | Method and apparatus for chromatographic purification |
| ES2985370T3 (es) * | 2011-11-10 | 2024-11-05 | Hoffmann La Roche | Sistema de cromatografía en columna preparativa |
| WO2013075740A1 (en) | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
| CN104411820B (zh) | 2012-06-29 | 2017-05-03 | Emd密理博公司 | 在蛋白纯化过程中灭活病毒的方法 |
| CA2911462C (en) * | 2013-05-06 | 2021-04-06 | Sanofi | Continuous multistep process for purifying antibodies |
| CN104237418B (zh) * | 2013-09-11 | 2015-11-18 | 青岛普仁仪器有限公司 | 免稀释作线性曲线的色谱仪及线性曲线测量方法 |
| KR20160054597A (ko) * | 2013-09-17 | 2016-05-16 | 가부시키가이샤 가네카 | 신규 항체 정제 방법 및 그로부터 얻어지는 항체, 및 양이온 교환기를 사용한 신규 항체 정제법 및 그로부터 얻어지는 항체 |
| US11286292B2 (en) * | 2014-02-07 | 2022-03-29 | Cmc Biologics A/S | Bioreactor arrangement and continuous process for producing and capturing a biopolymer |
| US10429359B2 (en) | 2014-02-14 | 2019-10-01 | Ge Healthcare Bio-Sciences Ab | Automated multi-step purification system |
| JP6331485B2 (ja) * | 2014-03-04 | 2018-05-30 | 株式会社島津製作所 | 液体クロマトグラフ及び液体クロマトグラフ分析方法 |
| EP3137484A1 (en) * | 2014-05-02 | 2017-03-08 | Novo Nordisk A/S | Integrated continuous biomanufacturing process |
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| JP6579515B2 (ja) * | 2015-08-10 | 2019-09-25 | 国立大学法人 岡山大学 | アポe含有hdlの測定方法及び測定装置 |
| KR102344339B1 (ko) * | 2016-04-04 | 2021-12-28 | 베링거 인겔하임 에르체파우 게엠베하 운트 코 카게 | 제제 정제의 실시간 모니터링 |
| GB201622343D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| WO2018140485A1 (en) | 2017-01-26 | 2018-08-02 | Counsyl, Inc. | Reagent delivery and waste management system |
| US11185830B2 (en) | 2017-09-06 | 2021-11-30 | Waters Technologies Corporation | Fluid mixer |
| FR3073424B1 (fr) | 2017-11-16 | 2022-03-25 | Novasep Process | Procede regule de separation d’un melange |
| GB201802593D0 (en) * | 2018-02-16 | 2018-04-04 | Fujifilm Diosynth Biotechnologies Uk Ltd | Rig |
| EP3546475A1 (en) | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| EP3774840A1 (en) * | 2018-03-27 | 2021-02-17 | Bristol-Myers Squibb Company | Real-time monitoring of protein concentration using ultraviolet signal |
| CN109453545A (zh) * | 2018-12-20 | 2019-03-12 | 上海兆维科技发展有限公司 | 层析柱洗脱液的配液装置 |
| EP3693732A1 (en) * | 2019-02-11 | 2020-08-12 | Bayer Aktiengesellschaft | Influencing a sequential chromatography in real-time |
| WO2020164956A1 (en) * | 2019-02-11 | 2020-08-20 | Bayer Aktiengesellschaft | Influencing a sequential chromatography in real-time |
| EP3763429A1 (en) * | 2019-07-08 | 2021-01-13 | Bayer Aktiengesellschaft | Influencing a sequential chromatography in real-time |
| EP3699697A1 (en) | 2019-02-25 | 2020-08-26 | Bayer Aktiengesellschaft | Automated simultaneous process control |
| FR3099066B1 (fr) | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
| EP4013539A1 (en) | 2019-08-12 | 2022-06-22 | Waters Technologies Corporation | Mixer for chromatography system |
| GB201911685D0 (en) * | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying monoclonal antibodies |
| GB201911686D0 (en) * | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying target substances |
| CN120044170A (zh) * | 2019-09-23 | 2025-05-27 | 建新公司 | 产品品质属性测量 |
| JP7388206B2 (ja) * | 2020-01-22 | 2023-11-29 | 株式会社島津製作所 | 液体クロマトグラフおよび分析方法 |
| CN113663364B (zh) * | 2020-05-14 | 2025-02-21 | 佛山汉腾生物科技有限公司 | 层析装置 |
| US11898999B2 (en) | 2020-07-07 | 2024-02-13 | Waters Technologies Corporation | Mixer for liquid chromatography |
| EP4179311B1 (en) | 2020-07-07 | 2025-07-30 | Waters Technologies Corporation | Combination mixer arrangement for noise reduction in fluid chromatography |
| EP4214503A1 (en) * | 2020-09-17 | 2023-07-26 | Computational International LLC | System and method for monitoring for the presence of elements |
| US11821882B2 (en) | 2020-09-22 | 2023-11-21 | Waters Technologies Corporation | Continuous flow mixer |
| JP2022091322A (ja) * | 2020-12-09 | 2022-06-21 | 株式会社島津製作所 | 液体クロマトグラフのpH管理システムおよびプログラム |
| CN117355747A (zh) | 2021-05-20 | 2024-01-05 | 沃特世科技公司 | 等分散分流混合器 |
| US20250179466A1 (en) * | 2022-03-03 | 2025-06-05 | Chromacon Ag | Chromatographic purification method and uses thereof |
| CN114797173A (zh) * | 2022-04-10 | 2022-07-29 | 南通星中细胞工程有限公司 | 一种用于外泌体的高效制备装置及制备方法 |
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| US4246101A (en) * | 1978-12-28 | 1981-01-20 | Pure Cycle Corporation | Water recycling system |
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| JPS62255865A (ja) | 1986-04-28 | 1987-11-07 | Hitachi Ltd | 液体クロマトグラフ |
| US4840730A (en) * | 1986-07-25 | 1989-06-20 | Sepragen Corporation | Chromatography system using horizontal flow columns |
| JP2581568B2 (ja) | 1987-10-08 | 1997-02-12 | 株式会社日立製作所 | イオンクロマトグラフイ装置 |
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| ATE147281T1 (de) * | 1991-03-28 | 1997-01-15 | Perseptive Biosystems Inc | Produktinformation in chromatographischem effluenten durch differenzbildung |
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| JP4959565B2 (ja) * | 2004-05-21 | 2012-06-27 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 低流量動作を可能にするためのhplc定流量ポンプの閉ループ流量制御 |
| US7642306B2 (en) | 2004-06-25 | 2010-01-05 | Johns Manville | Control of pH in formaldehyde-free binder systems |
| NZ588616A (en) | 2004-09-30 | 2012-05-25 | Bayer Healthcare Llc | An apparatus for separating a protein of interest comprising a purification system integrated with a particle removal system |
| EP1871503B2 (en) * | 2005-01-20 | 2025-04-23 | Waters Technologies Corporation | Methods for separating compounds |
| EP1716900A1 (en) * | 2005-04-29 | 2006-11-02 | Eidgenössische Technische Hochschule Zürich | Method and device for chromatographic purification |
| EP1775001A1 (en) | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Device for chromatographic separations |
| JP4939910B2 (ja) * | 2006-11-29 | 2012-05-30 | 株式会社東芝 | マイクロ化学分析システム及びマイクロ化学分析装置 |
| CN101678244B (zh) | 2007-04-17 | 2013-06-19 | 深度控股有限公司 | 用于连续膜吸附的方法和装置 |
| GB0709109D0 (en) | 2007-05-11 | 2007-06-20 | Enpar Technologies Inc | Wastewater ammonium extraction and electrolytic conversion to nitrogen gas |
| US20090149638A1 (en) * | 2007-10-03 | 2009-06-11 | Ley Arthur C | Systems and methods for purifying proteins |
| CN103396480A (zh) | 2008-05-15 | 2013-11-20 | 诺沃—诺迪斯克有限公司 | 抗体纯化方法 |
| WO2010124159A1 (en) | 2009-04-23 | 2010-10-28 | Xcellerex, Inc. | System and method for variable speed feedback control chromatography loading |
-
2009
- 2009-09-25 US US12/566,701 patent/US9527010B2/en active Active
-
2010
- 2010-09-20 JP JP2012530844A patent/JP5749270B2/ja active Active
- 2010-09-20 EP EP10819116.4A patent/EP2480305B1/en active Active
- 2010-09-20 IN IN1850DEN2012 patent/IN2012DN01850A/en unknown
- 2010-09-20 WO PCT/SE2010/051003 patent/WO2011037522A1/en not_active Ceased
- 2010-09-20 AU AU2010298768A patent/AU2010298768B2/en active Active
- 2010-09-20 CN CN201080043193.9A patent/CN102574026B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2480305B1 (en) | 2020-10-28 |
| WO2011037522A1 (en) | 2011-03-31 |
| EP2480305A4 (en) | 2014-07-02 |
| AU2010298768B2 (en) | 2015-07-02 |
| US9527010B2 (en) | 2016-12-27 |
| CN102574026B (zh) | 2015-10-07 |
| EP2480305A1 (en) | 2012-08-01 |
| AU2010298768A1 (en) | 2012-03-15 |
| CN102574026A (zh) | 2012-07-11 |
| JP5749270B2 (ja) | 2015-07-15 |
| JP2013506127A (ja) | 2013-02-21 |
| US20110073548A1 (en) | 2011-03-31 |
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