IN2012DN01850A - - Google Patents

Download PDF

Info

Publication number
IN2012DN01850A
IN2012DN01850A IN1850DEN2012A IN2012DN01850A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A IN 1850DEN2012 A IN1850DEN2012 A IN 1850DEN2012A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A
Authority
IN
India
Prior art keywords
separation
line
units
fluid
separation unit
Prior art date
Application number
Other languages
English (en)
Inventor
M Williams Alan
Kaletski Adam
Stack Lisa
G Go Daniel
Krasnansky John
A Wareheim David
Lin Bin
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43779133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN01850(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Publication of IN2012DN01850A publication Critical patent/IN2012DN01850A/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/461Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/362Cation-exchange
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/24Automatic injection systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/34Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
IN1850DEN2012 2009-09-25 2010-09-20 IN2012DN01850A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/566,701 US9527010B2 (en) 2009-09-25 2009-09-25 Separation system and method
PCT/SE2010/051003 WO2011037522A1 (en) 2009-09-25 2010-09-20 Separation system and method

Publications (1)

Publication Number Publication Date
IN2012DN01850A true IN2012DN01850A (enExample) 2015-08-21

Family

ID=43779133

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1850DEN2012 IN2012DN01850A (enExample) 2009-09-25 2010-09-20

Country Status (7)

Country Link
US (1) US9527010B2 (enExample)
EP (1) EP2480305B1 (enExample)
JP (1) JP5749270B2 (enExample)
CN (1) CN102574026B (enExample)
AU (1) AU2010298768B2 (enExample)
IN (1) IN2012DN01850A (enExample)
WO (1) WO2011037522A1 (enExample)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5961112B2 (ja) * 2009-09-25 2016-08-02 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 液体混合物の調製方法及びシステム
CA2787897A1 (en) * 2010-02-12 2011-08-18 Dsm Ip Assets B.V. Single unit antibody purification
EP2598515B1 (en) * 2010-07-30 2016-09-21 Pfizer Inc Tandem purification of proteins
EP2433952B1 (en) * 2010-09-20 2015-09-02 Asahi Kasei Bioprocess, Inc. Liquid chromatography system and method for protein separation and purification
JP2013540787A (ja) * 2010-11-01 2013-11-07 ディーエスエム アイピー アセッツ ビー.ブイ. 単一ユニットイオン交換クロマトグラフィー抗体精製
BR112013031906A2 (pt) * 2011-06-16 2016-12-13 Dsm Ip Assets Bv unidade única de cromatografia de purificação de anticorpo
WO2013028330A2 (en) * 2011-08-19 2013-02-28 Emd Millipore Corporation Methods of reducing level of one of more impurities in a sample during protein purification
EP2578286A1 (en) 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
ES2985370T3 (es) * 2011-11-10 2024-11-05 Hoffmann La Roche Sistema de cromatografía en columna preparativa
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN104411820B (zh) 2012-06-29 2017-05-03 Emd密理博公司 在蛋白纯化过程中灭活病毒的方法
CA2911462C (en) * 2013-05-06 2021-04-06 Sanofi Continuous multistep process for purifying antibodies
CN104237418B (zh) * 2013-09-11 2015-11-18 青岛普仁仪器有限公司 免稀释作线性曲线的色谱仪及线性曲线测量方法
KR20160054597A (ko) * 2013-09-17 2016-05-16 가부시키가이샤 가네카 신규 항체 정제 방법 및 그로부터 얻어지는 항체, 및 양이온 교환기를 사용한 신규 항체 정제법 및 그로부터 얻어지는 항체
US11286292B2 (en) * 2014-02-07 2022-03-29 Cmc Biologics A/S Bioreactor arrangement and continuous process for producing and capturing a biopolymer
US10429359B2 (en) 2014-02-14 2019-10-01 Ge Healthcare Bio-Sciences Ab Automated multi-step purification system
JP6331485B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ及び液体クロマトグラフ分析方法
EP3137484A1 (en) * 2014-05-02 2017-03-08 Novo Nordisk A/S Integrated continuous biomanufacturing process
US11835501B2 (en) 2015-07-13 2023-12-05 Sartorius Stedim Chromatography Systems Ltd. Optimizing operating binding capacity for a multiple column chromatography process
JP6579515B2 (ja) * 2015-08-10 2019-09-25 国立大学法人 岡山大学 アポe含有hdlの測定方法及び測定装置
KR102344339B1 (ko) * 2016-04-04 2021-12-28 베링거 인겔하임 에르체파우 게엠베하 운트 코 카게 제제 정제의 실시간 모니터링
GB201622343D0 (en) * 2016-12-29 2017-02-15 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
WO2018140485A1 (en) 2017-01-26 2018-08-02 Counsyl, Inc. Reagent delivery and waste management system
US11185830B2 (en) 2017-09-06 2021-11-30 Waters Technologies Corporation Fluid mixer
FR3073424B1 (fr) 2017-11-16 2022-03-25 Novasep Process Procede regule de separation d’un melange
GB201802593D0 (en) * 2018-02-16 2018-04-04 Fujifilm Diosynth Biotechnologies Uk Ltd Rig
EP3546475A1 (en) 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
EP3774840A1 (en) * 2018-03-27 2021-02-17 Bristol-Myers Squibb Company Real-time monitoring of protein concentration using ultraviolet signal
CN109453545A (zh) * 2018-12-20 2019-03-12 上海兆维科技发展有限公司 层析柱洗脱液的配液装置
EP3693732A1 (en) * 2019-02-11 2020-08-12 Bayer Aktiengesellschaft Influencing a sequential chromatography in real-time
WO2020164956A1 (en) * 2019-02-11 2020-08-20 Bayer Aktiengesellschaft Influencing a sequential chromatography in real-time
EP3763429A1 (en) * 2019-07-08 2021-01-13 Bayer Aktiengesellschaft Influencing a sequential chromatography in real-time
EP3699697A1 (en) 2019-02-25 2020-08-26 Bayer Aktiengesellschaft Automated simultaneous process control
FR3099066B1 (fr) 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
EP4013539A1 (en) 2019-08-12 2022-06-22 Waters Technologies Corporation Mixer for chromatography system
GB201911685D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying monoclonal antibodies
GB201911686D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying target substances
CN120044170A (zh) * 2019-09-23 2025-05-27 建新公司 产品品质属性测量
JP7388206B2 (ja) * 2020-01-22 2023-11-29 株式会社島津製作所 液体クロマトグラフおよび分析方法
CN113663364B (zh) * 2020-05-14 2025-02-21 佛山汉腾生物科技有限公司 层析装置
US11898999B2 (en) 2020-07-07 2024-02-13 Waters Technologies Corporation Mixer for liquid chromatography
EP4179311B1 (en) 2020-07-07 2025-07-30 Waters Technologies Corporation Combination mixer arrangement for noise reduction in fluid chromatography
EP4214503A1 (en) * 2020-09-17 2023-07-26 Computational International LLC System and method for monitoring for the presence of elements
US11821882B2 (en) 2020-09-22 2023-11-21 Waters Technologies Corporation Continuous flow mixer
JP2022091322A (ja) * 2020-12-09 2022-06-21 株式会社島津製作所 液体クロマトグラフのpH管理システムおよびプログラム
CN117355747A (zh) 2021-05-20 2024-01-05 沃特世科技公司 等分散分流混合器
US20250179466A1 (en) * 2022-03-03 2025-06-05 Chromacon Ag Chromatographic purification method and uses thereof
CN114797173A (zh) * 2022-04-10 2022-07-29 南通星中细胞工程有限公司 一种用于外泌体的高效制备装置及制备方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3918907A (en) * 1973-10-29 1975-11-11 Beckman Instruments Inc Micro automatic amino acid analysis process and system
US4246101A (en) * 1978-12-28 1981-01-20 Pure Cycle Corporation Water recycling system
US4762796A (en) 1981-10-05 1988-08-09 Exxon Research And Engineering Company pH control of a process stream
JPS62255865A (ja) 1986-04-28 1987-11-07 Hitachi Ltd 液体クロマトグラフ
US4840730A (en) * 1986-07-25 1989-06-20 Sepragen Corporation Chromatography system using horizontal flow columns
JP2581568B2 (ja) 1987-10-08 1997-02-12 株式会社日立製作所 イオンクロマトグラフイ装置
US5114576A (en) * 1990-02-15 1992-05-19 Trineos Prevention of contaminants buildup in captured and recirculated water systems
ATE147281T1 (de) * 1991-03-28 1997-01-15 Perseptive Biosystems Inc Produktinformation in chromatographischem effluenten durch differenzbildung
US5792371A (en) 1996-08-22 1998-08-11 Iosolutions Incorporated Method of disinfecting water with iodine species
US6799883B1 (en) 1999-12-20 2004-10-05 Air Liquide America L.P. Method for continuously blending chemical solutions
WO2003025156A2 (en) * 2001-09-18 2003-03-27 Affinium Pharmaceuticals, Inc. Methods and apparatuses for purification
WO2003083467A2 (de) 2002-03-28 2003-10-09 Siemens Aktiengesellschaft Gaschromatograph und verfahren zur gaschromatographischen analyse eines stoffgemischs
JP2004077329A (ja) 2002-08-20 2004-03-11 Japan Organo Co Ltd クロマト分離装置
US6972415B2 (en) * 2002-09-26 2005-12-06 R-Can Environmental Inc. Fluid treatment system with UV sensor and intelligent driver
US20040124253A1 (en) * 2002-10-17 2004-07-01 Bergwin Gregory A. Injection apparatus for irrigation system
CA2506317A1 (en) 2002-11-18 2004-06-03 Taurus Hsa Llc Method for continuous, automated blending of solutions from acids and bases
EP1628729A2 (en) * 2003-05-16 2006-03-01 Cryobiophysica, Inc. External gradient chromatofocusing
US7632410B2 (en) * 2003-08-21 2009-12-15 Christopher Heiss Universal water purification system
WO2005040787A1 (en) 2003-10-17 2005-05-06 Ge Healthcare Bio-Sciences Ab Chromatography system, method and software for the separation of biomolecules
US7072742B1 (en) 2003-10-17 2006-07-04 Technikrom, Inc. Accurate blending module and method
US8271139B2 (en) 2003-10-17 2012-09-18 Asahi Kasei Bioprocess, Inc. Multi-stage accurate blending system and method
AU2005242998B2 (en) * 2004-05-17 2010-05-27 Firmenich Sa New multidimensional gas chromatography apparatus and analyte transfer procedure using a multiple-cool strand interface
JP4959565B2 (ja) * 2004-05-21 2012-06-27 ウオーターズ・テクノロジーズ・コーポレイシヨン 低流量動作を可能にするためのhplc定流量ポンプの閉ループ流量制御
US7642306B2 (en) 2004-06-25 2010-01-05 Johns Manville Control of pH in formaldehyde-free binder systems
NZ588616A (en) 2004-09-30 2012-05-25 Bayer Healthcare Llc An apparatus for separating a protein of interest comprising a purification system integrated with a particle removal system
EP1871503B2 (en) * 2005-01-20 2025-04-23 Waters Technologies Corporation Methods for separating compounds
EP1716900A1 (en) * 2005-04-29 2006-11-02 Eidgenössische Technische Hochschule Zürich Method and device for chromatographic purification
EP1775001A1 (en) 2005-10-13 2007-04-18 Xendo Holding B.V. Device for chromatographic separations
JP4939910B2 (ja) * 2006-11-29 2012-05-30 株式会社東芝 マイクロ化学分析システム及びマイクロ化学分析装置
CN101678244B (zh) 2007-04-17 2013-06-19 深度控股有限公司 用于连续膜吸附的方法和装置
GB0709109D0 (en) 2007-05-11 2007-06-20 Enpar Technologies Inc Wastewater ammonium extraction and electrolytic conversion to nitrogen gas
US20090149638A1 (en) * 2007-10-03 2009-06-11 Ley Arthur C Systems and methods for purifying proteins
CN103396480A (zh) 2008-05-15 2013-11-20 诺沃—诺迪斯克有限公司 抗体纯化方法
WO2010124159A1 (en) 2009-04-23 2010-10-28 Xcellerex, Inc. System and method for variable speed feedback control chromatography loading

Also Published As

Publication number Publication date
EP2480305B1 (en) 2020-10-28
WO2011037522A1 (en) 2011-03-31
EP2480305A4 (en) 2014-07-02
AU2010298768B2 (en) 2015-07-02
US9527010B2 (en) 2016-12-27
CN102574026B (zh) 2015-10-07
EP2480305A1 (en) 2012-08-01
AU2010298768A1 (en) 2012-03-15
CN102574026A (zh) 2012-07-11
JP5749270B2 (ja) 2015-07-15
JP2013506127A (ja) 2013-02-21
US20110073548A1 (en) 2011-03-31

Similar Documents

Publication Publication Date Title
IN2012DN01850A (enExample)
WO2011150604A8 (zh) 净化饮水装置及其控制方法
EA201101427A1 (ru) Настраиваемые устройства регулирования потока для использования при добыче углеводородов
MX358373B (es) Sistema y metodo para tratamiento de agua.
MX342035B (es) Sistema de control de flujo de fluido para el interior de pozos que tiene un modulo fluidico con una red en puente y metodo de uso del mismo.
BRPI0913857A2 (pt) sistema de drenagem de líquido
NZ594012A (en) A gravity fed water treatment system comprising a foam filter element, a biological layer and a restriction orifice to limit the flow of water through the system
MX2013010347A (es) Sistemas y metodos para controlar el flujo de fluidos corporales.
MY156507A (en) Alternating flow resistance increases and decreases for propagating pressure pulses in a subterranean well
MX2023000906A (es) Un aparato de purificacion de agua y un metodo para controlar por lo menos una propiedad del fluido en un aparato de purificacion de agua.
MX2009012058A (es) Estructura pre-ensamblada de control de flujo y sistema de filtracion de medios relacionados.
GB201208417D0 (en) Flushing system
ATE527874T1 (de) Strömungstechnische ausrichtungs- und sortiervorrichtung für pflanzenembryos
MY157460A (en) Filter comprising a halogen release system and chitosan
WO2020005069A3 (en) A mobile system for continuous, automatic, online monitoring of water quality and particle sampling in a drinking water distribution network
MY168233A (en) Salt water desalination apparatus
WO2012081027A3 (en) Filtration system and components there for
EP2045494A3 (en) Electronic bypass system for a fluid treatment system
MX2016015260A (es) Productos de silice a partir de fluidos geotermicos por osmosis inversa.
ZA201103186B (en) Method for the filtration of a bioreactor liquid from a bioreactor;cross-flow membrane module,and bioreactor membrane system
PH12017500312A1 (en) Anaerobic membrane bioreactor system
MA34044B1 (fr) Dispositif pour filtrer et separer des milieux en ecoulement
WO2012145763A3 (en) Fluid filtration systems having gas introducer devices and associated systems and methods
PH12013500681A1 (en) Water treatment in at least one membrane filtration unit for assisted recovery of hydrocarbons
WO2013156988A3 (en) Effecting high recovery desalination with pressure driven membranes