IN2012DN00899A - - Google Patents

Info

Publication number
IN2012DN00899A
IN2012DN00899A IN899DEN2012A IN2012DN00899A IN 2012DN00899 A IN2012DN00899 A IN 2012DN00899A IN 899DEN2012 A IN899DEN2012 A IN 899DEN2012A IN 2012DN00899 A IN2012DN00899 A IN 2012DN00899A
Authority
IN
India
Prior art keywords
culture system
cell culture
cell
continuous
less
Prior art date
Application number
Other languages
English (en)
Inventor
Grillberger Leopold
Reiter Manfred
Fleischanderl Daniel
Original Assignee
Baxter Healthcare Sa
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare Sa, Baxter Int filed Critical Baxter Healthcare Sa
Publication of IN2012DN00899A publication Critical patent/IN2012DN00899A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/006Cell injection or fusion devices
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0056Xeno-free medium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/98Xeno-free medium and culture conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/00051Methods of production or purification of viral material
    • C12N2710/00052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24087ADAMTS13 endopeptidase (3.4.24.87)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
IN899DEN2012 2009-07-31 2010-08-02 IN2012DN00899A (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23031309P 2009-07-31 2009-07-31
PCT/EP2010/061191 WO2011012725A1 (en) 2009-07-31 2010-08-02 Method of producing a polypeptide or virus of interest in a continuous cell culture

Publications (1)

Publication Number Publication Date
IN2012DN00899A true IN2012DN00899A (tr) 2015-04-03

Family

ID=42668436

Family Applications (1)

Application Number Title Priority Date Filing Date
IN899DEN2012 IN2012DN00899A (tr) 2009-07-31 2010-08-02

Country Status (22)

Country Link
US (4) US8580554B2 (tr)
EP (2) EP2459697B1 (tr)
JP (2) JP5808742B2 (tr)
KR (2) KR101885046B1 (tr)
CN (1) CN102549142B (tr)
AU (1) AU2010277490B2 (tr)
BR (1) BR112012002137B8 (tr)
CA (1) CA2769354A1 (tr)
CO (1) CO6491119A2 (tr)
DK (1) DK2459697T3 (tr)
EA (1) EA022219B1 (tr)
ES (1) ES2705206T3 (tr)
HR (1) HRP20182165T1 (tr)
IN (1) IN2012DN00899A (tr)
MX (2) MX2012001274A (tr)
NZ (1) NZ597742A (tr)
PL (1) PL2459697T3 (tr)
PT (1) PT2459697T (tr)
SG (1) SG178176A1 (tr)
SI (1) SI2459697T1 (tr)
TR (1) TR201900213T4 (tr)
WO (1) WO2011012725A1 (tr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL286298B (en) 2010-07-08 2022-08-01 Baxalta Inc A method to generate high molecular weight substituted vwf in cell culture
HRP20211494T1 (hr) * 2011-01-17 2021-12-24 F. Hoffmann - La Roche Ag Uređaj za odvajanje
RU2600886C2 (ru) 2011-05-13 2016-10-27 Октафарма Аг Способ повышения продуктивности эукариотических клеток в продуцировании рекомбинантного fviii
LT2837680T (lt) * 2011-07-01 2020-07-10 Amgen Inc. Žinduolių ląstelių kultūra
CN203129697U (zh) 2013-02-05 2013-08-14 客贝利(厦门)休闲用品有限公司 一种帐篷架杆
SI2782997T1 (en) 2011-11-24 2018-04-30 Genethon A rolling lentiviral vector manufacturing system compatible with industrial pharmaceutical applications
US9574167B2 (en) 2013-02-15 2017-02-21 Pharyx, Inc. Methods and apparatus for independent control of product and reactant concentrations
SG10201709131UA (en) 2013-03-08 2017-12-28 Genzyme Corp Continuous purification of therapeutic proteins
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
WO2014146933A1 (en) * 2013-03-19 2014-09-25 Cmc Biologics A/S A method for producing a product (e.g. polypeptide) in a continuous cell culture fermentation process.
JP6851827B2 (ja) * 2013-08-30 2021-03-31 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 細胞培養中でのウイルスの大規模製造
US11390663B2 (en) 2013-10-11 2022-07-19 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
TWI709570B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析法及製法
WO2015149143A2 (en) 2014-04-01 2015-10-08 Advantech Bioscience Farmacêutica Ltda. Stable factor viii formulations with low sugar-glycine
CN106456720A (zh) 2014-04-01 2017-02-22 爱德技术生物科学有限公司 在无钙作为赋形剂下因子viii的稳定性
WO2015188224A1 (en) * 2014-06-13 2015-12-17 Csl Limited Improved production of recombinant von willebrand factor in a bioreactor
CN108884428B (zh) * 2016-01-26 2023-04-11 勃林格殷格翰国际公司 对连续流动搅拌釜反应器细胞培养系统的连接灌注
SG11201809051YA (en) * 2016-04-15 2018-11-29 Boehringer Ingelheim Int Cell retention device and method
SI3559203T1 (sl) * 2016-12-21 2021-03-31 F. Hoffmann-La Roche Ag Nadzor rasti evkariontskih celic
MX2020011614A (es) 2018-05-01 2020-12-09 Amgen Inc Anticuerpos con perfiles de glicanos modulados.
WO2019239780A1 (ja) * 2018-06-15 2019-12-19 富士フイルム株式会社 細胞培養方法、細胞培養装置、及び生産物の製造方法
CA3110666A1 (en) 2018-08-31 2020-03-05 Genzyme Corporation Sterile chromatography resin and use thereof in manufacturing processes
CN113355297A (zh) * 2021-06-23 2021-09-07 吉林冠界生物技术有限公司 一种灌流式培养全悬浮mdck细胞生产重组禽流感病毒的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019512A (en) 1989-03-17 1991-05-28 Baxter International Inc. Spin filter for removing substantially cell-free culture medium from suspension cell culture system
US5626734A (en) 1995-08-18 1997-05-06 University Technologies International, Inc. Filter for perfusion cultures of animal cells and the like
WO2002029083A2 (en) 2000-10-02 2002-04-11 Novo Nordisk A/S Industrial-scale serum-free production of recombinant proteins in mammalian cells
WO2003045995A2 (en) * 2001-11-28 2003-06-05 Sandoz Gmbh Cell culture process
TWI384069B (zh) 2004-08-27 2013-02-01 Pfizer Ireland Pharmaceuticals 多胜肽之製法
PL1902141T3 (pl) 2005-06-17 2012-12-31 Baxalta Inc Kompozycje o działaniu trombolitycznym zawierające ADAMTS13
KR101423344B1 (ko) * 2006-01-04 2014-07-30 백스터 인터내셔널 인코포레이티드 올리고펩티드-무함유 세포 배양 배지를 이용하여 단백질을 발현시키는 방법
PT2235197T (pt) * 2007-12-27 2017-10-11 Baxalta Inc Processos para cultura de células

Also Published As

Publication number Publication date
HRP20182165T1 (hr) 2019-03-08
BR112012002137B8 (pt) 2020-05-12
KR20170077286A (ko) 2017-07-05
JP2013500710A (ja) 2013-01-10
DK2459697T3 (en) 2019-01-28
CA2769354A1 (en) 2011-02-03
US10745672B2 (en) 2020-08-18
JP5808742B2 (ja) 2015-11-10
MX353610B (es) 2018-01-18
BR112012002137B1 (pt) 2020-04-14
SG178176A1 (en) 2012-03-29
KR101752789B1 (ko) 2017-06-30
CN102549142B (zh) 2014-07-16
US20110086411A1 (en) 2011-04-14
US8580554B2 (en) 2013-11-12
PL2459697T3 (pl) 2019-04-30
NZ597742A (en) 2014-02-28
JP2015062436A (ja) 2015-04-09
US10221400B2 (en) 2019-03-05
US20180051261A1 (en) 2018-02-22
JP6177260B2 (ja) 2017-08-09
MX2012001274A (es) 2012-06-01
EP3480292A1 (en) 2019-05-08
AU2010277490B2 (en) 2014-08-28
CO6491119A2 (es) 2012-07-31
US9650612B2 (en) 2017-05-16
AU2010277490A1 (en) 2012-02-09
BR112012002137A2 (pt) 2015-09-15
KR101885046B1 (ko) 2018-08-02
WO2011012725A8 (en) 2011-05-05
ES2705206T3 (es) 2019-03-22
PT2459697T (pt) 2019-01-21
KR20120038531A (ko) 2012-04-23
SI2459697T1 (sl) 2019-03-29
CN102549142A (zh) 2012-07-04
US20190153400A1 (en) 2019-05-23
US20140038264A1 (en) 2014-02-06
WO2011012725A1 (en) 2011-02-03
EA201270213A1 (ru) 2012-06-29
EA022219B1 (ru) 2015-11-30
EP2459697B1 (en) 2018-10-17
EP2459697A1 (en) 2012-06-06
TR201900213T4 (tr) 2019-02-21

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