SG11201809051YA - Cell retention device and method - Google Patents

Cell retention device and method

Info

Publication number
SG11201809051YA
SG11201809051YA SG11201809051YA SG11201809051YA SG11201809051YA SG 11201809051Y A SG11201809051Y A SG 11201809051YA SG 11201809051Y A SG11201809051Y A SG 11201809051YA SG 11201809051Y A SG11201809051Y A SG 11201809051YA SG 11201809051Y A SG11201809051Y A SG 11201809051YA
Authority
SG
Singapore
Prior art keywords
international
ridgefield
box
retention device
boehringer ingelheim
Prior art date
Application number
SG11201809051YA
Inventor
jonathan Coffman
Scott Godfrey
Samantha Wang
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of SG11201809051YA publication Critical patent/SG11201809051YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 HO 111110111011110 1111111111 010 MN III International Bureau 0.. .... .. (10) International Publication Number ...... ... (43) International Publication Date WO 2017/180814 Al 19 October 2017(19.10.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C12M 1/00 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, PCT/US2017/027318 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, 13 April 2017 (13.04.2017) KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (25) Filing Language: English NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (26) Publication Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (30) Priority Data: ZA, ZM, ZW. 62/322,825 15 April 2016 (15.04.2016) US 62/330,912 3 May 2016 (03.05.2016) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) (72) Applicant: BOEHRINGER INGELHEIM INTERNA- GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TIONAL GMBH [DE/DE]; Binger Strasse 173, 55216 In- TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, gelheim am Rhein (DE). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, Inventors (for US only): COFFMAN, Jonathan; c/o VP, IP Legal, Boehringer Ingelheim USA Corp., 900 Ridge- LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, bury Rd., P.O. Box 368, Ridgefield, Connecticut 06877- 0368 (US). GODFREY, Scott; c/o VP, IP Legal, GW, KM, ML, MR, NE, SN, TD, TG). Boehringer Ingelheim USA Corp., 900 Ridgebury Rd., Declarations under Rule 4.17: P.O. Box 368, Ridgefield, Connecticut 06877-0368 (US). — as to applicant's entitlement to apply for and be granted a WANG, Samantha; c/o VP, IP Legal, Boehringer Ingel- heim USA Corp., 900 Ridgebury Rd., P.O. Box 368, patent (Rule 4.17(ii)) Ridgefield, Connecticut 06877-0368 (US). Published: Agents: DATLOW, Philip I. et al.; Boehringer Ingelheim — with international search report (Art. 21(3)) (74) Pharmaceuticals, Inc., 900 Ridgebury Road, P.O. Box 368, Ridgefield, CT 06877-0368 (US). 1-1 7r 11 GC © GC 11 IN 1-1 (54) Title: CELL RETENTION DEVICE AND METHOD 0 ei (57) : The subject technology relates to a cell retention device and method for use in a perfusion cell culture system where en. ) the cell retention device includes a hollow-fiber filter having an average pore size ranging from about 0.5 to about 20 um and having ,7 1 ,1 9 the ability to operate under perfusion cell culture conditions for up to 35 days without being clogged or losing its product sieving ability by more than 20%.
SG11201809051YA 2016-04-15 2017-04-13 Cell retention device and method SG11201809051YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662322825P 2016-04-15 2016-04-15
US201662330912P 2016-05-03 2016-05-03
PCT/US2017/027318 WO2017180814A1 (en) 2016-04-15 2017-04-13 Cell retention device and method

Publications (1)

Publication Number Publication Date
SG11201809051YA true SG11201809051YA (en) 2018-11-29

Family

ID=58606594

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809051YA SG11201809051YA (en) 2016-04-15 2017-04-13 Cell retention device and method

Country Status (6)

Country Link
US (1) US20190169559A1 (en)
EP (1) EP3443064A1 (en)
KR (1) KR102414290B1 (en)
CN (1) CN109072154A (en)
SG (1) SG11201809051YA (en)
WO (1) WO2017180814A1 (en)

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CA3088023C (en) 2018-03-08 2023-03-21 Repligen Corporation Tangential flow depth filtration systems and methods of filtration using same
US20220145230A1 (en) * 2019-05-15 2022-05-12 Life Technologies Corporation Cell Settler Apparatus Systems and Methods for Perfusion Processes
CN110257227B (en) * 2019-06-20 2020-08-04 江南大学 Bioreactor for animal cell culture
TWI777364B (en) * 2020-01-15 2022-09-11 大陸商上海藥明生物技術有限公司 Apparatus and method for continuous harvesting of biomass produced from cultured cells
KR102230957B1 (en) * 2020-05-18 2021-03-23 경북대학교 산학협력단 Extra-cellular vesicles filtrating apparatus
KR102267199B1 (en) * 2020-10-30 2021-06-21 경북대학교 산학협력단 Tangential Flow Filtration based Extracellular vesicle purification system with self-feedback protocol controller via real-time monitoring
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
WO2024024337A1 (en) * 2022-07-28 2024-02-01 株式会社ダイセル Device for purifying and concentrating liquid that contains minute useful substance, and method for producing purified concentrate that contains minute useful substance using said device

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US8026096B1 (en) * 1998-10-08 2011-09-27 Protein Sciences Corporation In vivo active erythropoietin produced in insect cells
US6544424B1 (en) 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
AU2003248780A1 (en) 2002-07-10 2004-01-23 Pall Corporation Hollow fiber membrane systems
ES2456015T3 (en) * 2004-03-05 2014-04-21 Dsm Ip Assets B.V. Procedure for culturing cells by continuous perfusion and alternating tangential flow
WO2008109674A2 (en) * 2007-03-05 2008-09-12 Caridianbct, Inc. Cell expansion system and methods of use
WO2010003759A2 (en) 2008-06-17 2010-01-14 Dsm Ip Assets B.V. Cell culturing method
US8580554B2 (en) * 2009-07-31 2013-11-12 Baxter International Inc. Method of producing a polypeptide or virus of interest in a continuous cell culture
BR112012010949A2 (en) * 2009-11-10 2017-11-07 Toray Industries hollow membrane module for use in producing a chemical and process for producing a chemical using the hollow membrane module for use in producing a chemical
US9446354B2 (en) * 2010-08-25 2016-09-20 Repligen Corporation Device, system and process for modification or concentration of cell-depleted fluid
US9101857B2 (en) 2011-04-26 2015-08-11 Therapeutic Proteins International, LLC Gas scrubbed perfusion filter
EP3103861B1 (en) * 2012-06-21 2020-09-30 Baxalta GmbH Virus filtration of cell culture media
AU2014318420B2 (en) * 2013-09-16 2020-01-16 Genzyme Corporation Methods and systems for processing a cell culture
US10358626B2 (en) * 2016-04-12 2019-07-23 Artemis Biosystems, Inc. Perfusion filtration systems

Also Published As

Publication number Publication date
US20190169559A1 (en) 2019-06-06
EP3443064A1 (en) 2019-02-20
WO2017180814A1 (en) 2017-10-19
KR102414290B1 (en) 2022-06-29
KR20180134407A (en) 2018-12-18
CN109072154A (en) 2018-12-21

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