IN170957B - - Google Patents

Info

Publication number
IN170957B
IN170957B IN81/CAL/90A IN81CA1990A IN170957B IN 170957 B IN170957 B IN 170957B IN 81CA1990 A IN81CA1990 A IN 81CA1990A IN 170957 B IN170957 B IN 170957B
Authority
IN
India
Application number
IN81/CAL/90A
Other languages
English (en)
Inventor
Bruno Silvestrini
Leandro Baiocchi
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of IN170957B publication Critical patent/IN170957B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IN81/CAL/90A 1989-02-07 1990-01-30 IN170957B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8947620A IT1230441B (it) 1989-02-07 1989-02-07 Eteri della serie dell'indazolo

Publications (1)

Publication Number Publication Date
IN170957B true IN170957B (de) 1992-06-20

Family

ID=11261479

Family Applications (1)

Application Number Title Priority Date Filing Date
IN81/CAL/90A IN170957B (de) 1989-02-07 1990-01-30

Country Status (36)

Country Link
US (2) US4999367A (de)
EP (1) EP0382276B1 (de)
JP (1) JP2870925B2 (de)
KR (1) KR0145525B1 (de)
CN (2) CN1046505C (de)
AR (1) AR247386A1 (de)
AT (1) ATE127115T1 (de)
AU (1) AU624895B2 (de)
BG (1) BG50273A3 (de)
CA (1) CA2009503C (de)
CZ (1) CZ280121B6 (de)
DD (2) DD291995A5 (de)
DE (2) DE69021902T2 (de)
DK (1) DK0382276T3 (de)
EG (1) EG19170A (de)
ES (1) ES2020171T3 (de)
FI (1) FI102678B (de)
GE (1) GEP19971030B (de)
GR (2) GR910300073T1 (de)
HU (1) HU204793B (de)
IL (1) IL93132A (de)
IN (1) IN170957B (de)
IT (1) IT1230441B (de)
LT (1) LT3604B (de)
LV (1) LV10612B (de)
NZ (1) NZ232258A (de)
PE (1) PE25091A1 (de)
PH (1) PH26552A (de)
PL (2) PL163720B1 (de)
PT (1) PT93067B (de)
RO (1) RO106252B1 (de)
RU (3) RU2066318C1 (de)
SK (1) SK278441B6 (de)
UA (1) UA26852C2 (de)
YU (1) YU47943B (de)
ZA (1) ZA90644B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1253703B (it) * 1991-04-22 1995-08-23 Angelini Francesco Ist Ricerca Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie
IT1293795B1 (it) * 1997-07-28 1999-03-10 Angelini Ricerche Spa Farmaco attivo nel ridurre la produzione di proteina mcp-1
US5943270A (en) * 1997-11-26 1999-08-24 Intel Corporation Two-transistor DRAM cell for logic process technology
US7514463B2 (en) 2004-08-20 2009-04-07 University Of Kansas Lonidamine analogues and their use in male contraception and cancer treatment
ITMI20062254A1 (it) 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
AR070813A1 (es) 2008-03-07 2010-05-05 Acraf Nuevos derivados de 1- bencil -3-hidroximetilindazol y su utilizacion en el tratamiento de enfermedades basadas en la expresion de mcp-1 y cx3cr1
LT2262778T (lt) 2008-03-07 2019-11-11 Acraf 1-benzil-3-hidroksimetilindazolo dariniai ir jų panaudojimas gydant ligas, pagrįstas mcp-1, cxcr1 ir p40 raiška
EP2254869B1 (de) * 2008-03-07 2017-05-31 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. Novel 1-benzyl-3-hydroxymethylindazol derivate und deren verwendung zur behandlung von erkrankungen in verbindung mit der expression von cx3cr1 and p40
CA2765461C (en) 2009-08-03 2017-04-11 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.S.P.A. Process for the preparation of 1-benzyl-3-hydr0xymethyl-1h-indaz0le and its derivatives and required magnesium intermediates
UA108742C2 (uk) 2009-09-23 2015-06-10 Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
CA3095012C (en) 2012-05-01 2023-02-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
WO2013171316A1 (en) 2012-05-18 2013-11-21 Sanofi Pyridine derivatives and their use in the treatment of conditions associated with pathological thrombus formation
RU2645344C2 (ru) 2012-05-18 2018-02-21 Санофи Производные пиразола и их применение в качестве lpar5 антагонистов
CN108047136B (zh) * 2017-12-20 2021-07-09 长春普华制药股份有限公司 一种苄达酸的精制方法
EP3990433A4 (de) * 2019-06-25 2023-07-26 Translatum Medicus Inc. Verfahren zur herstellung von 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropansäure und ihren derivaten
CN113929627A (zh) * 2021-10-19 2022-01-14 吕梁学院 一种宾达利的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL28032A (en) * 1966-08-29 1971-08-25 Acraf Indazol-3-yl-oxyalkanoic acids and process for the preparation thereof
US3470298A (en) * 1969-01-29 1969-09-30 Acraf Topical anti-inflammatory composition containing (indazole-3-yl)-oxyalkanoic acids
IT1131779B (it) 1980-07-29 1986-06-25 Acraf Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione
IT1189052B (it) 1981-11-27 1988-01-28 Acraf Trattamento della cataratta
IT1194564B (it) 1983-04-18 1988-09-22 Acraf Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa
IT1197805B (it) 1986-08-01 1988-12-06 Acraf Metodo per il tratamento di lenti a contatto

Also Published As

Publication number Publication date
AU4906690A (en) 1990-08-16
ZA90644B (en) 1991-01-30
CN1034016C (zh) 1997-02-12
DE382276T1 (de) 1991-11-28
RU2066318C1 (ru) 1996-09-10
DD295363A5 (de) 1991-10-31
DE69021902T2 (de) 1996-05-23
EP0382276B1 (de) 1995-08-30
HUT53088A (en) 1990-09-28
GR3018165T3 (en) 1996-02-29
YU20690A (sh) 1992-07-20
DE69021902D1 (de) 1995-10-05
LV10612B (en) 1995-08-20
AU624895B2 (en) 1992-06-25
US5112986A (en) 1992-05-12
JP2870925B2 (ja) 1999-03-17
PE25091A1 (es) 1991-08-17
UA26852C2 (uk) 1999-12-29
PT93067B (pt) 1995-12-29
YU47943B (sh) 1996-07-24
IT8947620A0 (it) 1989-02-07
LV10612A (lv) 1995-04-20
CN1046505C (zh) 1999-11-17
RO106252B1 (ro) 1993-03-31
HU204793B (en) 1992-02-28
IL93132A (en) 1994-05-30
FI102678B1 (fi) 1999-01-29
GEP19971030B (en) 1997-06-13
SK56390A3 (en) 1997-05-07
ES2020171T3 (es) 1995-12-01
EG19170A (en) 1994-11-30
EP0382276A3 (en) 1990-12-12
GR910300073T1 (en) 1991-11-15
PT93067A (pt) 1990-08-31
PL163730B1 (pl) 1994-04-29
JPH02240065A (ja) 1990-09-25
BG50273A3 (en) 1992-06-15
FI102678B (fi) 1999-01-29
ATE127115T1 (de) 1995-09-15
CA2009503A1 (en) 1990-08-07
DK0382276T3 (da) 1996-01-15
LT3604B (en) 1995-12-27
KR0145525B1 (ko) 1998-08-17
CA2009503C (en) 2000-04-11
US4999367A (en) 1991-03-12
CZ56390A3 (en) 1995-06-14
HU900689D0 (en) 1990-04-28
PH26552A (en) 1992-08-19
RU2055071C1 (ru) 1996-02-27
DD291995A5 (de) 1991-07-18
CN1044810A (zh) 1990-08-22
SK278441B6 (en) 1997-05-07
ES2020171A4 (es) 1991-08-01
IL93132A0 (en) 1990-11-05
LTIP872A (en) 1995-03-27
CN1088201A (zh) 1994-06-22
IT1230441B (it) 1991-10-23
NZ232258A (en) 1991-06-25
CZ280121B6 (cs) 1995-11-15
KR900012913A (ko) 1990-09-03
EP0382276A2 (de) 1990-08-16
RU2044729C1 (ru) 1995-09-27
AR247386A1 (es) 1994-12-29
PL163720B1 (pl) 1994-04-29
FI900577A0 (fi) 1990-02-06

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