IL98256A - Transformed pyridines and processes for making the appropriate pyridines - Google Patents

Transformed pyridines and processes for making the appropriate pyridines

Info

Publication number
IL98256A
IL98256A IL9825691A IL9825691A IL98256A IL 98256 A IL98256 A IL 98256A IL 9825691 A IL9825691 A IL 9825691A IL 9825691 A IL9825691 A IL 9825691A IL 98256 A IL98256 A IL 98256A
Authority
IL
Israel
Prior art keywords
compound
formula
optionally
substituents
alkyl
Prior art date
Application number
IL9825691A
Other languages
English (en)
Hebrew (he)
Other versions
IL98256A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to IL11301191A priority Critical patent/IL113011A/xx
Publication of IL98256A0 publication Critical patent/IL98256A0/xx
Publication of IL98256A publication Critical patent/IL98256A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL9825691A 1990-05-31 1991-05-24 Transformed pyridines and processes for making the appropriate pyridines IL98256A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL11301191A IL113011A (en) 1990-05-31 1991-05-24 R-mandelic acid salt of (2s,3s)-3- (2-methoxybenzylamino)-2- phenylpiperidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53126590A 1990-05-31 1990-05-31

Publications (2)

Publication Number Publication Date
IL98256A0 IL98256A0 (en) 1992-06-21
IL98256A true IL98256A (en) 1995-11-27

Family

ID=24116944

Family Applications (3)

Application Number Title Priority Date Filing Date
IL9825691A IL98256A (en) 1990-05-31 1991-05-24 Transformed pyridines and processes for making the appropriate pyridines
IL11301191A IL113011A (en) 1990-05-31 1991-05-24 R-mandelic acid salt of (2s,3s)-3- (2-methoxybenzylamino)-2- phenylpiperidine
IL11301195A IL113011A0 (en) 1990-05-31 1995-03-16 R-mandelic acid salt of phenylpiperidine derivative

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL11301191A IL113011A (en) 1990-05-31 1991-05-24 R-mandelic acid salt of (2s,3s)-3- (2-methoxybenzylamino)-2- phenylpiperidine
IL11301195A IL113011A0 (en) 1990-05-31 1995-03-16 R-mandelic acid salt of phenylpiperidine derivative

Country Status (26)

Country Link
EP (1) EP0532515B1 (hu)
JP (2) JPH0794439B2 (hu)
KR (1) KR0160142B1 (hu)
CN (2) CN1037768C (hu)
AT (1) ATE144498T1 (hu)
AU (1) AU648558B2 (hu)
BR (1) BR9106518A (hu)
CA (1) CA2080249C (hu)
CZ (1) CZ284663B6 (hu)
DE (1) DE69122866T2 (hu)
DK (1) DK0532515T3 (hu)
ES (1) ES2093099T3 (hu)
FI (1) FI101376B (hu)
GR (1) GR3022079T3 (hu)
HU (1) HU226529B1 (hu)
IE (1) IE911841A1 (hu)
IL (3) IL98256A (hu)
MY (1) MY107819A (hu)
NO (1) NO180083C (hu)
NZ (2) NZ250217A (hu)
PL (2) PL168236B1 (hu)
PT (1) PT97796B (hu)
RU (1) RU2077531C1 (hu)
WO (1) WO1991018878A1 (hu)
YU (1) YU48030B (hu)
ZA (1) ZA914133B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332817A (en) * 1990-01-04 1994-07-26 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles
UA41251C2 (uk) * 1990-01-04 2001-09-17 Пфайзер, Інк. Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
EP0581777A1 (en) * 1991-03-26 1994-02-09 Pfizer Inc. Stereoselective preparation of substituted piperidines
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
ATE161821T1 (de) * 1991-11-12 1998-01-15 Pfizer Azyklische ethylendiaminderivate als 'substance p rezeptor' antagonisten
ATE194340T1 (de) * 1992-12-10 2000-07-15 Pfizer Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
DK0700384T3 (da) 1993-05-28 1997-12-08 Pfizer fremgangsmåde til fremstilling og opløsning af 2-phenyl-3-aminopiperidin
TW397825B (en) * 1994-10-14 2000-07-11 Novartis Ag Aroyl-piperidine derivatives
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
CA2291734A1 (en) * 1997-06-27 1999-01-07 Merck Sharp & Dohme Limited Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents
WO2000005212A1 (en) * 1998-07-21 2000-02-03 Syngenta Participations Ag 3-substituted pyridine compounds and related synthesis
JP2011016751A (ja) * 2009-07-08 2011-01-27 Sumitomo Chemical Co Ltd 光学活性３−アミノピペリジン−１−カルボキシレート化合物の製造方法およびその製造方法に用いられる中間体
CN111808017B (zh) * 2020-08-05 2023-11-28 国家纳米科学中心 一种含氮杂环化合物及其制备方法和应用
CN116162055B (zh) * 2023-03-10 2023-09-12 山东汇智药物研究有限公司 一种用n-氧化吡啶衍生物制备哌啶衍生物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125170A (en) * 1976-04-12 1977-10-20 Yoshitomi Pharmaceut Ind Ltd Pyridine derivatives
CA1160229A (en) * 1979-03-13 1984-01-10 Pieter T. Haken Pyridyliminomethylbenzene derivatives
CA1231710A (en) * 1979-07-19 1988-01-19 Haken Pieter Ten Heterocyclic compounds having fungicidal, herbicidal and plant-growth regulating properties
GB2056974B (en) * 1979-07-19 1984-02-29 Shell Int Research Heterocyclic acylamino compounds having fungicidal herbicidal and plant-growth regulating properties
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
US4552960A (en) * 1983-06-20 1985-11-12 Eli Lilly And Company Fungicidal amines
FR2662696A2 (fr) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Antagonistes de la serotonine, leur preparation et medicaments les contenant.
UA41251C2 (uk) * 1990-01-04 2001-09-17 Пфайзер, Інк. Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі

Also Published As

Publication number Publication date
PT97796A (pt) 1992-02-28
FI925415A (fi) 1992-11-27
HU226529B1 (en) 2009-03-30
AU7770391A (en) 1991-12-31
DE69122866T2 (de) 1997-02-20
JPH07206819A (ja) 1995-08-08
GR3022079T3 (en) 1997-03-31
DE69122866D1 (de) 1996-11-28
EP0532515A1 (en) 1993-03-24
DK0532515T3 (da) 1997-04-21
FI925415A0 (fi) 1992-11-27
HU9203761D0 (en) 1993-03-29
MY107819A (en) 1996-06-29
IL113011A0 (en) 1995-06-29
NO924598D0 (no) 1992-11-27
NZ238340A (en) 1994-06-27
WO1991018878A1 (en) 1991-12-12
KR0160142B1 (ko) 1998-12-01
NO924598L (no) 1992-11-27
YU96291A (sh) 1994-06-10
FI101376B1 (fi) 1998-06-15
RU2077531C1 (ru) 1997-04-20
CN1056876A (zh) 1991-12-11
YU48030B (sh) 1996-10-09
PL168236B1 (pl) 1996-01-31
CN1154636C (zh) 2004-06-23
IE911841A1 (en) 1991-12-04
CS162391A3 (en) 1992-02-19
IL98256A0 (en) 1992-06-21
JP2549609B2 (ja) 1996-10-30
ZA914133B (en) 1993-01-27
JPH0794439B2 (ja) 1995-10-11
NO180083C (no) 1997-02-12
ES2093099T3 (es) 1996-12-16
FI101376B (fi) 1998-06-15
KR930700443A (ko) 1993-03-15
BR9106518A (pt) 1993-05-25
CN1037768C (zh) 1998-03-18
NO180083B (no) 1996-11-04
AU648558B2 (en) 1994-04-28
CN1183408A (zh) 1998-06-03
EP0532515B1 (en) 1996-10-23
IL113011A (en) 1999-09-22
JPH05502238A (ja) 1993-04-22
CZ284663B6 (cs) 1999-01-13
PT97796B (pt) 1998-10-30
CA2080249A1 (en) 1991-12-01
HUT68166A (en) 1995-05-29
PL169187B1 (pl) 1996-06-28
CA2080249C (en) 1996-11-19
ATE144498T1 (de) 1996-11-15
NZ250217A (en) 1995-05-26

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees