IL94459A - צורה תרופתית ותהליך להכנתה - Google Patents

צורה תרופתית ותהליך להכנתה

Info

Publication number
IL94459A
IL94459A IL9445990A IL9445990A IL94459A IL 94459 A IL94459 A IL 94459A IL 9445990 A IL9445990 A IL 9445990A IL 9445990 A IL9445990 A IL 9445990A IL 94459 A IL94459 A IL 94459A
Authority
IL
Israel
Prior art keywords
freeze
paste
dried
pharmaceutical form
unitary
Prior art date
Application number
IL9445990A
Other languages
English (en)
Other versions
IL94459A0 (en
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of IL94459A0 publication Critical patent/IL94459A0/xx
Publication of IL94459A publication Critical patent/IL94459A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
  • Filtering Materials (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL9445990A 1989-05-24 1990-05-21 צורה תרופתית ותהליך להכנתה IL94459A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8906781A FR2647343B1 (fr) 1989-05-24 1989-05-24 Nouvelle forme pharmaceutique poreuse et sa preparation

Publications (2)

Publication Number Publication Date
IL94459A0 IL94459A0 (en) 1991-03-10
IL94459A true IL94459A (he) 1995-01-24

Family

ID=9381955

Family Applications (2)

Application Number Title Priority Date Filing Date
IL9445990A IL94459A (he) 1989-05-24 1990-05-21 צורה תרופתית ותהליך להכנתה
IL94460A IL94460A0 (en) 1989-05-24 1990-05-21 Pharmaceutical compositions containing imipramine or derivatives thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL94460A IL94460A0 (en) 1989-05-24 1990-05-21 Pharmaceutical compositions containing imipramine or derivatives thereof

Country Status (24)

Country Link
US (1) US5244881A (he)
EP (2) EP0399903B1 (he)
JP (1) JP2948271B2 (he)
KR (1) KR0163423B1 (he)
AT (2) ATE83663T1 (he)
AU (2) AU631888B2 (he)
CA (2) CA2017360A1 (he)
DD (1) DD297915A5 (he)
DE (2) DE69000641T2 (he)
DK (2) DK0399902T3 (he)
ES (2) ES2054289T3 (he)
FI (1) FI103712B (he)
FR (1) FR2647343B1 (he)
GR (1) GR3006655T3 (he)
IE (2) IE64370B1 (he)
IL (2) IL94459A (he)
NO (1) NO180517C (he)
NZ (2) NZ233766A (he)
PL (1) PL285327A1 (he)
PT (2) PT94138B (he)
TW (1) TW257672B (he)
WO (1) WO1990014089A1 (he)
YU (1) YU100790A (he)
ZA (2) ZA903895B (he)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69231457T2 (de) * 1991-06-21 2001-05-23 Takeda Chemical Industries Ltd Zyklodextrin-Zusammensetzung enthaltend Fumagillol-Derivate
DE69227467T2 (de) 1991-12-24 1999-04-22 Yamanouchi Pharmaceutical Co., Ltd., Tokio/Tokyo Intrabukkal desintegrierende zubereitung und ihre herstellung
GB9318880D0 (en) * 1993-09-11 1993-10-27 Smithkline Beecham Plc Pharmaceutical composition
BR9507768A (pt) * 1994-05-27 1997-09-02 Farmarc Nederland Bv Composição farmacêutica
ATE421318T1 (de) * 1997-02-20 2009-02-15 Massachusetts Inst Technology Darreichungsform, welche rasche dispersionseigenschaften entfaltet, anwendungsverfahren sowie verfahren zur herstellung derselben
BE1011251A3 (fr) * 1997-07-03 1999-06-01 Ucb Sa Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine.
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
HUP0101564A3 (en) * 1998-02-05 2002-06-28 Novartis Ag Compositions containing epothilone
IT1304190B1 (it) * 1998-12-18 2001-03-08 Euphar Group Srl Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche
US6287603B1 (en) * 1999-09-16 2001-09-11 Nestec S.A. Cyclodextrin flavor delivery systems
CN101632642B (zh) 2002-01-15 2011-06-08 Ucb法奇姆股份有限公司 口感和稳定性改善的配方
EP1487774B1 (en) 2002-02-25 2018-09-19 Diffusion Pharmaceuticals LLC Bipolar trans carotenoid salts and their uses
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
DE10239531A1 (de) * 2002-08-23 2004-03-04 Gulbins, Erich, Prof. Dr. Prophylaxe und Therapie von Infektionserkrankungen
DE10248314A1 (de) * 2002-10-16 2004-04-29 Dr. Suwelack Skin & Health Care Ag Verwendung von Formkörpern zur äußeren Anwendung
FR2876910B1 (fr) * 2004-10-21 2007-04-13 Pierre Fabre Medicament Sa Complexe comprenant la mequitazine, une cyclodextrine et un agent d'interaction
NZ561664A (en) * 2005-02-24 2011-02-25 Diffusion Pharmaceuticals Llc Trans carotenoids, their synthesis, formulation and uses
DE102005041860A1 (de) * 2005-09-02 2007-03-08 Schering Ag Nanopartikulärer Einschluss- und Ladungskomplex für pharmazeutische Formulierungen
CN101687757A (zh) 2007-04-13 2010-03-31 扩散药品有限公司 双极性反式类胡萝卜素作为预治疗及其在周围血管疾病的治疗中的应用
JP2009091309A (ja) * 2007-10-10 2009-04-30 Japan Organo Co Ltd バコパモニエラエキスを含有する組成物およびその製造方法ならびに飲食品
AU2008319225B2 (en) 2007-10-31 2016-09-29 Diffusion Pharmaceuticals Llc A new class of therapeutics that enhance small molecule diffusion
EP2344137B1 (en) * 2008-09-05 2015-12-02 Johnson & Johnson Consumer Inc. Method for making cetirizine tablets
EP2445339B1 (en) 2009-06-22 2019-08-07 Diffusion Pharmaceuticals LLC Diffusion enhancing compound and its use with a thrombolytic
JP2013527231A (ja) 2010-06-02 2013-06-27 ディフュージョン・ファーマシューティカルズ・エルエルシー 双極性トランスカロテノイドの経口製剤
SG10201507554RA (en) * 2010-09-13 2015-10-29 Bev Rx Inc Aqueous drug delivery system comprising off - flavor masking agent
RU2609198C1 (ru) * 2016-01-25 2017-01-30 Закрытое Акционерное Общество "БИОКОМ" Твердая лекарственная форма имипрамина немедленного высвобождения и способ ее получения
CN109152839A (zh) 2016-03-24 2019-01-04 扩散药品有限公司 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5443570B2 (he) * 1972-10-27 1979-12-20
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
US4165382A (en) * 1977-10-17 1979-08-21 Jose Pozuelo Method of pharmacologically treating schizophrenia with alpha-methyl-para-tyrosine
US4284555A (en) * 1979-04-27 1981-08-18 Schering Corporation 7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4349472A (en) * 1979-04-27 1982-09-14 Schering Corporation (S)-8(1-Adamantanecarbonyloxy)-7-chloro-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
US4477378A (en) * 1980-02-05 1984-10-16 Schering Corp. Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
WO1986003198A1 (fr) * 1984-11-27 1986-06-05 Dainippon Pharmaceutical Co., Ltd. Derives de 2-(1-piperazinyle)-4-substitue phenylquinoline, procede de preparation et composition medicinale les contenant
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition

Also Published As

Publication number Publication date
CA2017355A1 (fr) 1990-11-24
IL94460A0 (en) 1991-03-10
EP0399903A1 (fr) 1990-11-28
KR900017570A (ko) 1990-12-19
CA2017360A1 (fr) 1990-11-24
NZ233784A (en) 1993-04-28
PT94139A (pt) 1991-01-08
EP0399902B1 (fr) 1993-12-22
DE69000641D1 (de) 1993-02-04
PT94138B (pt) 1996-12-31
DK0399903T3 (da) 1993-02-08
ATE83663T1 (de) 1993-01-15
KR0163423B1 (ko) 1998-12-01
ATE98867T1 (de) 1994-01-15
FI103712B1 (fi) 1999-08-31
GR3006655T3 (he) 1993-06-30
TW257672B (he) 1995-09-21
JPH0356412A (ja) 1991-03-12
DK0399902T3 (da) 1994-02-14
NO902280L (no) 1990-11-26
NO902280D0 (no) 1990-05-23
DE69005359D1 (de) 1994-02-03
FR2647343A1 (fr) 1990-11-30
ES2062437T3 (es) 1994-12-16
DE69005359T2 (de) 1994-05-05
ES2054289T3 (es) 1994-08-01
US5244881A (en) 1993-09-14
DE69000641T2 (de) 1993-06-09
FR2647343B1 (fr) 1994-05-06
IE64370B1 (en) 1995-07-26
PT94138A (pt) 1991-01-08
NZ233766A (en) 1991-08-27
IL94459A0 (en) 1991-03-10
IE901821L (en) 1990-11-24
ZA903895B (en) 1991-03-27
ZA903978B (en) 1991-03-27
EP0399902A1 (fr) 1990-11-28
AU5582890A (en) 1991-01-10
IE901862L (en) 1990-11-24
AU631888B2 (en) 1992-12-10
DD297915A5 (de) 1992-01-30
PL285327A1 (en) 1991-02-11
FI103712B (fi) 1999-08-31
EP0399903B1 (fr) 1992-12-23
JP2948271B2 (ja) 1999-09-13
WO1990014089A1 (fr) 1990-11-29
PT94139B (pt) 1996-12-31
AU623779B2 (en) 1992-05-21
NO180517B (no) 1997-01-27
IE63317B1 (en) 1995-04-05
FI902553A0 (fi) 1990-05-23
AU5743390A (en) 1990-12-18
NO180517C (no) 1997-05-07
YU100790A (en) 1992-05-28

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