IL93187A - Pharmaceutical preparations containing the acid compound aryl or troaryl-1-alkyl-pyrrole-2-carboxylate are used to treat interleuk-related conditions - Google Patents

Pharmaceutical preparations containing the acid compound aryl or troaryl-1-alkyl-pyrrole-2-carboxylate are used to treat interleuk-related conditions

Info

Publication number
IL93187A
IL93187A IL9318790A IL9318790A IL93187A IL 93187 A IL93187 A IL 93187A IL 9318790 A IL9318790 A IL 9318790A IL 9318790 A IL9318790 A IL 9318790A IL 93187 A IL93187 A IL 93187A
Authority
IL
Israel
Prior art keywords
pyrrole
carboxylic acid
composition
alkyl
biphenyl
Prior art date
Application number
IL9318790A
Other languages
English (en)
Hebrew (he)
Other versions
IL93187A0 (en
Inventor
Parker Roger Alan
Ku George
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL93187A0 publication Critical patent/IL93187A0/xx
Publication of IL93187A publication Critical patent/IL93187A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
IL9318790A 1989-01-31 1990-01-26 Pharmaceutical preparations containing the acid compound aryl or troaryl-1-alkyl-pyrrole-2-carboxylate are used to treat interleuk-related conditions IL93187A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30414189A 1989-01-31 1989-01-31

Publications (2)

Publication Number Publication Date
IL93187A0 IL93187A0 (en) 1990-11-05
IL93187A true IL93187A (en) 1994-12-29

Family

ID=23175237

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9318790A IL93187A (en) 1989-01-31 1990-01-26 Pharmaceutical preparations containing the acid compound aryl or troaryl-1-alkyl-pyrrole-2-carboxylate are used to treat interleuk-related conditions

Country Status (17)

Country Link
EP (1) EP0381141B1 (de)
JP (1) JP2841305B2 (de)
KR (1) KR0139288B1 (de)
CN (1) CN1022754C (de)
AR (1) AR245694A1 (de)
AT (1) ATE135702T1 (de)
AU (1) AU629290B2 (de)
CA (1) CA2008616C (de)
DE (1) DE69025967T2 (de)
ES (1) ES2087093T3 (de)
FI (1) FI900464A0 (de)
HU (1) HU209290B (de)
IL (1) IL93187A (de)
NO (1) NO174887C (de)
NZ (1) NZ232278A (de)
PT (1) PT93009A (de)
ZA (1) ZA90554B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
AU625688B2 (en) * 1989-01-31 1992-07-16 Merrell Dow Pharmaceuticals Inc. Method of using aryl- or heteroaryl-1-alkyl-pyrrole-2- carboxylic acid compounds in the treatment of interleukin-1 mediated conditions
JP5925121B2 (ja) 2009-07-10 2016-05-25 ザ ジェネラル ホスピタル コーポレイション 副腎皮質ステロイド合成を阻害しないエトミデート類似体
CN102114430B (zh) * 2009-12-30 2013-06-05 上海睿智化学研究有限公司 催化剂、其制备方法及n-烷基吡咯衍生物的制备方法
IN2014DN06132A (de) 2012-01-13 2015-08-14 Gen Hospital Corp

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4112112A (en) * 1976-06-29 1978-09-05 Merck & Co., Inc. Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect
JPS54128567A (en) * 1978-03-28 1979-10-05 Teijin Ltd 1-substituted-4-acyl-2-pyrrolecarboxylic acid derivative

Also Published As

Publication number Publication date
KR0139288B1 (ko) 1998-05-15
NO174887C (no) 1994-07-27
PT93009A (pt) 1990-07-31
EP0381141A2 (de) 1990-08-08
HU209290B (en) 1994-04-28
CN1022754C (zh) 1993-11-17
NZ232278A (en) 1992-07-28
ZA90554B (en) 1990-10-31
IL93187A0 (en) 1990-11-05
CN1044653A (zh) 1990-08-15
AU4875990A (en) 1990-08-09
EP0381141B1 (de) 1996-03-20
HUT53868A (en) 1990-12-28
CA2008616C (en) 2000-07-18
CA2008616A1 (en) 1990-07-31
ATE135702T1 (de) 1996-04-15
KR900011725A (ko) 1990-08-02
NO900432L (no) 1990-08-01
HU900592D0 (en) 1990-04-28
NO900432D0 (no) 1990-01-30
JPH02247165A (ja) 1990-10-02
DE69025967D1 (de) 1996-04-25
AR245694A1 (es) 1994-02-28
AU629290B2 (en) 1992-10-01
EP0381141A3 (de) 1991-11-21
DE69025967T2 (de) 1996-08-29
NO174887B (no) 1994-04-18
FI900464A0 (fi) 1990-01-30
JP2841305B2 (ja) 1998-12-24
ES2087093T3 (es) 1996-07-16

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Legal Events

Date Code Title Description
RH Patent void
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.