DE69025967T2 - Aryl- oder Heteroaryl-1-alkyl-pyrrol-2-carbonsäure-Derivate, zur Behandlung von durch Interleukin-1 hervorgerufenen Erkrankungen - Google Patents
Aryl- oder Heteroaryl-1-alkyl-pyrrol-2-carbonsäure-Derivate, zur Behandlung von durch Interleukin-1 hervorgerufenen ErkrankungenInfo
- Publication number
- DE69025967T2 DE69025967T2 DE69025967T DE69025967T DE69025967T2 DE 69025967 T2 DE69025967 T2 DE 69025967T2 DE 69025967 T DE69025967 T DE 69025967T DE 69025967 T DE69025967 T DE 69025967T DE 69025967 T2 DE69025967 T2 DE 69025967T2
- Authority
- DE
- Germany
- Prior art keywords
- interleukin
- pyrrole
- heteroaryl
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30414189A | 1989-01-31 | 1989-01-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69025967D1 DE69025967D1 (de) | 1996-04-25 |
DE69025967T2 true DE69025967T2 (de) | 1996-08-29 |
Family
ID=23175237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69025967T Expired - Fee Related DE69025967T2 (de) | 1989-01-31 | 1990-01-30 | Aryl- oder Heteroaryl-1-alkyl-pyrrol-2-carbonsäure-Derivate, zur Behandlung von durch Interleukin-1 hervorgerufenen Erkrankungen |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0381141B1 (de) |
JP (1) | JP2841305B2 (de) |
KR (1) | KR0139288B1 (de) |
CN (1) | CN1022754C (de) |
AR (1) | AR245694A1 (de) |
AT (1) | ATE135702T1 (de) |
AU (1) | AU629290B2 (de) |
CA (1) | CA2008616C (de) |
DE (1) | DE69025967T2 (de) |
ES (1) | ES2087093T3 (de) |
FI (1) | FI900464A0 (de) |
HU (1) | HU209290B (de) |
IL (1) | IL93187A (de) |
NO (1) | NO174887C (de) |
NZ (1) | NZ232278A (de) |
PT (1) | PT93009A (de) |
ZA (1) | ZA90554B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
ZA90555B (en) * | 1989-01-31 | 1990-10-31 | Merrell Pharma Inc | Method of using aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds in the treatment of interleukin-1 mediated conditions |
CN102548964B (zh) | 2009-07-10 | 2014-09-24 | 通用医疗公司 | 不抑制肾上腺皮质类固醇合成的依托咪酯类似物 |
CN102114430B (zh) * | 2009-12-30 | 2013-06-05 | 上海睿智化学研究有限公司 | 催化剂、其制备方法及n-烷基吡咯衍生物的制备方法 |
SI2802325T1 (sl) | 2012-01-13 | 2017-04-26 | The General Hospital Corporation | Anestetične spojine in pripadajoči postopki za uporabo |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4112112A (en) * | 1976-06-29 | 1978-09-05 | Merck & Co., Inc. | Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect |
JPS54128567A (en) * | 1978-03-28 | 1979-10-05 | Teijin Ltd | 1-substituted-4-acyl-2-pyrrolecarboxylic acid derivative |
-
1990
- 1990-01-25 AR AR90316008A patent/AR245694A1/es active
- 1990-01-25 ZA ZA90554A patent/ZA90554B/xx unknown
- 1990-01-25 CA CA002008616A patent/CA2008616C/en not_active Expired - Fee Related
- 1990-01-25 AU AU48759/90A patent/AU629290B2/en not_active Ceased
- 1990-01-26 IL IL9318790A patent/IL93187A/en not_active IP Right Cessation
- 1990-01-29 NZ NZ232278A patent/NZ232278A/en unknown
- 1990-01-29 JP JP2016304A patent/JP2841305B2/ja not_active Expired - Fee Related
- 1990-01-30 PT PT93009A patent/PT93009A/pt not_active Application Discontinuation
- 1990-01-30 KR KR1019900000994A patent/KR0139288B1/ko not_active IP Right Cessation
- 1990-01-30 FI FI900464A patent/FI900464A0/fi not_active IP Right Cessation
- 1990-01-30 EP EP90101809A patent/EP0381141B1/de not_active Expired - Lifetime
- 1990-01-30 NO NO900432A patent/NO174887C/no unknown
- 1990-01-30 HU HU90592A patent/HU209290B/hu not_active IP Right Cessation
- 1990-01-30 AT AT90101809T patent/ATE135702T1/de not_active IP Right Cessation
- 1990-01-30 DE DE69025967T patent/DE69025967T2/de not_active Expired - Fee Related
- 1990-01-30 ES ES90101809T patent/ES2087093T3/es not_active Expired - Lifetime
- 1990-01-31 CN CN90100431A patent/CN1022754C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2087093T3 (es) | 1996-07-16 |
NO174887C (no) | 1994-07-27 |
DE69025967D1 (de) | 1996-04-25 |
HUT53868A (en) | 1990-12-28 |
JPH02247165A (ja) | 1990-10-02 |
NO900432D0 (no) | 1990-01-30 |
NO174887B (no) | 1994-04-18 |
KR900011725A (ko) | 1990-08-02 |
IL93187A0 (en) | 1990-11-05 |
AR245694A1 (es) | 1994-02-28 |
IL93187A (en) | 1994-12-29 |
NO900432L (no) | 1990-08-01 |
ZA90554B (en) | 1990-10-31 |
CA2008616C (en) | 2000-07-18 |
EP0381141A3 (de) | 1991-11-21 |
CN1044653A (zh) | 1990-08-15 |
HU900592D0 (en) | 1990-04-28 |
EP0381141A2 (de) | 1990-08-08 |
PT93009A (pt) | 1990-07-31 |
CA2008616A1 (en) | 1990-07-31 |
NZ232278A (en) | 1992-07-28 |
AU629290B2 (en) | 1992-10-01 |
EP0381141B1 (de) | 1996-03-20 |
ATE135702T1 (de) | 1996-04-15 |
AU4875990A (en) | 1990-08-09 |
HU209290B (en) | 1994-04-28 |
KR0139288B1 (ko) | 1998-05-15 |
FI900464A0 (fi) | 1990-01-30 |
JP2841305B2 (ja) | 1998-12-24 |
CN1022754C (zh) | 1993-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |