NO900432L - Fremgangsmaate for fremstilling av nye aryl- eller heteroaryl-1-alkyl-pyrrol-2-carboxylsyreforbindelser. - Google Patents

Fremgangsmaate for fremstilling av nye aryl- eller heteroaryl-1-alkyl-pyrrol-2-carboxylsyreforbindelser.

Info

Publication number
NO900432L
NO900432L NO90900432A NO900432A NO900432L NO 900432 L NO900432 L NO 900432L NO 90900432 A NO90900432 A NO 90900432A NO 900432 A NO900432 A NO 900432A NO 900432 L NO900432 L NO 900432L
Authority
NO
Norway
Prior art keywords
pyrrol
heteroaryl
alkyl
procedure
preparation
Prior art date
Application number
NO90900432A
Other languages
English (en)
Other versions
NO174887C (no
NO900432D0 (no
NO174887B (no
Inventor
Roger Alan Parker
George Ku
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO900432D0 publication Critical patent/NO900432D0/no
Publication of NO900432L publication Critical patent/NO900432L/no
Publication of NO174887B publication Critical patent/NO174887B/no
Publication of NO174887C publication Critical patent/NO174887C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
NO900432A 1989-01-31 1990-01-30 Analogifremgangsmåte for fremstilling av terapeutisk aktive aryl- alkyl-pyrrol-2-carboxylsyreforbindelser NO174887C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30414189A 1989-01-31 1989-01-31

Publications (4)

Publication Number Publication Date
NO900432D0 NO900432D0 (no) 1990-01-30
NO900432L true NO900432L (no) 1990-08-01
NO174887B NO174887B (no) 1994-04-18
NO174887C NO174887C (no) 1994-07-27

Family

ID=23175237

Family Applications (1)

Application Number Title Priority Date Filing Date
NO900432A NO174887C (no) 1989-01-31 1990-01-30 Analogifremgangsmåte for fremstilling av terapeutisk aktive aryl- alkyl-pyrrol-2-carboxylsyreforbindelser

Country Status (17)

Country Link
EP (1) EP0381141B1 (no)
JP (1) JP2841305B2 (no)
KR (1) KR0139288B1 (no)
CN (1) CN1022754C (no)
AR (1) AR245694A1 (no)
AT (1) ATE135702T1 (no)
AU (1) AU629290B2 (no)
CA (1) CA2008616C (no)
DE (1) DE69025967T2 (no)
ES (1) ES2087093T3 (no)
FI (1) FI900464A0 (no)
HU (1) HU209290B (no)
IL (1) IL93187A (no)
NO (1) NO174887C (no)
NZ (1) NZ232278A (no)
PT (1) PT93009A (no)
ZA (1) ZA90554B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
ZA90555B (en) * 1989-01-31 1990-10-31 Merrell Pharma Inc Method of using aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds in the treatment of interleukin-1 mediated conditions
CA2767112C (en) 2009-07-10 2018-06-19 The General Hospital Corporation Etomidate analogues that do not inhibit adrenocortical steroid synthesis
CN102114430B (zh) * 2009-12-30 2013-06-05 上海睿智化学研究有限公司 催化剂、其制备方法及n-烷基吡咯衍生物的制备方法
ES2617536T3 (es) 2012-01-13 2017-06-19 The General Hospital Corporation Compuestos anestésicos y métodos relacionados de uso

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4112112A (en) * 1976-06-29 1978-09-05 Merck & Co., Inc. Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect
JPS54128567A (en) * 1978-03-28 1979-10-05 Teijin Ltd 1-substituted-4-acyl-2-pyrrolecarboxylic acid derivative

Also Published As

Publication number Publication date
ES2087093T3 (es) 1996-07-16
CN1022754C (zh) 1993-11-17
HU900592D0 (en) 1990-04-28
ZA90554B (en) 1990-10-31
ATE135702T1 (de) 1996-04-15
EP0381141A2 (en) 1990-08-08
HU209290B (en) 1994-04-28
JPH02247165A (ja) 1990-10-02
PT93009A (pt) 1990-07-31
AU629290B2 (en) 1992-10-01
IL93187A0 (en) 1990-11-05
EP0381141A3 (en) 1991-11-21
NO174887C (no) 1994-07-27
NO900432D0 (no) 1990-01-30
CA2008616A1 (en) 1990-07-31
AR245694A1 (es) 1994-02-28
FI900464A0 (fi) 1990-01-30
NZ232278A (en) 1992-07-28
IL93187A (en) 1994-12-29
HUT53868A (en) 1990-12-28
KR900011725A (ko) 1990-08-02
JP2841305B2 (ja) 1998-12-24
CN1044653A (zh) 1990-08-15
EP0381141B1 (en) 1996-03-20
AU4875990A (en) 1990-08-09
DE69025967D1 (de) 1996-04-25
CA2008616C (en) 2000-07-18
KR0139288B1 (ko) 1998-05-15
NO174887B (no) 1994-04-18
DE69025967T2 (de) 1996-08-29

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