ZA90554B - Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions - Google Patents
Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditionsInfo
- Publication number
- ZA90554B ZA90554B ZA90554A ZA90554A ZA90554B ZA 90554 B ZA90554 B ZA 90554B ZA 90554 A ZA90554 A ZA 90554A ZA 90554 A ZA90554 A ZA 90554A ZA 90554 B ZA90554 B ZA 90554B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrrole
- heteroaryl
- alkyl
- carboxylic acid
- acid compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30414189A | 1989-01-31 | 1989-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA90554B true ZA90554B (en) | 1990-10-31 |
Family
ID=23175237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA90554A ZA90554B (en) | 1989-01-31 | 1990-01-25 | Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0381141B1 (de) |
| JP (1) | JP2841305B2 (de) |
| KR (1) | KR0139288B1 (de) |
| CN (1) | CN1022754C (de) |
| AR (1) | AR245694A1 (de) |
| AT (1) | ATE135702T1 (de) |
| AU (1) | AU629290B2 (de) |
| CA (1) | CA2008616C (de) |
| DE (1) | DE69025967T2 (de) |
| ES (1) | ES2087093T3 (de) |
| FI (1) | FI900464A7 (de) |
| HU (1) | HU209290B (de) |
| IL (1) | IL93187A (de) |
| NO (1) | NO174887C (de) |
| NZ (1) | NZ232278A (de) |
| PT (1) | PT93009A (de) |
| ZA (1) | ZA90554B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
| AU625688B2 (en) * | 1989-01-31 | 1992-07-16 | Merrell Dow Pharmaceuticals Inc. | Method of using aryl- or heteroaryl-1-alkyl-pyrrole-2- carboxylic acid compounds in the treatment of interleukin-1 mediated conditions |
| WO2011005969A2 (en) * | 2009-07-10 | 2011-01-13 | The General Hospital Corporation | Etomidate analogues that do not inhibit adrenocortical steroid synthesis |
| CN102114430B (zh) * | 2009-12-30 | 2013-06-05 | 上海睿智化学研究有限公司 | 催化剂、其制备方法及n-烷基吡咯衍生物的制备方法 |
| CA2861071C (en) | 2012-01-13 | 2017-09-12 | The General Hospital Corporation | Etomidate and metomidate derivatives and their use as anesthetics |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4112112A (en) * | 1976-06-29 | 1978-09-05 | Merck & Co., Inc. | Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect |
-
1990
- 1990-01-25 AU AU48759/90A patent/AU629290B2/en not_active Ceased
- 1990-01-25 AR AR90316008A patent/AR245694A1/es active
- 1990-01-25 ZA ZA90554A patent/ZA90554B/xx unknown
- 1990-01-25 CA CA002008616A patent/CA2008616C/en not_active Expired - Fee Related
- 1990-01-26 IL IL9318790A patent/IL93187A/en not_active IP Right Cessation
- 1990-01-29 NZ NZ232278A patent/NZ232278A/en unknown
- 1990-01-29 JP JP2016304A patent/JP2841305B2/ja not_active Expired - Fee Related
- 1990-01-30 EP EP90101809A patent/EP0381141B1/de not_active Expired - Lifetime
- 1990-01-30 NO NO900432A patent/NO174887C/no unknown
- 1990-01-30 ES ES90101809T patent/ES2087093T3/es not_active Expired - Lifetime
- 1990-01-30 DE DE69025967T patent/DE69025967T2/de not_active Expired - Fee Related
- 1990-01-30 PT PT93009A patent/PT93009A/pt not_active Application Discontinuation
- 1990-01-30 KR KR1019900000994A patent/KR0139288B1/ko not_active Expired - Fee Related
- 1990-01-30 AT AT90101809T patent/ATE135702T1/de not_active IP Right Cessation
- 1990-01-30 HU HU90592A patent/HU209290B/hu not_active IP Right Cessation
- 1990-01-30 FI FI900464A patent/FI900464A7/fi not_active IP Right Cessation
- 1990-01-31 CN CN90100431A patent/CN1022754C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO174887C (no) | 1994-07-27 |
| DE69025967D1 (de) | 1996-04-25 |
| PT93009A (pt) | 1990-07-31 |
| CA2008616C (en) | 2000-07-18 |
| JPH02247165A (ja) | 1990-10-02 |
| EP0381141A2 (de) | 1990-08-08 |
| FI900464A7 (fi) | 1990-08-01 |
| CN1044653A (zh) | 1990-08-15 |
| CN1022754C (zh) | 1993-11-17 |
| HU209290B (en) | 1994-04-28 |
| ES2087093T3 (es) | 1996-07-16 |
| KR0139288B1 (ko) | 1998-05-15 |
| EP0381141B1 (de) | 1996-03-20 |
| EP0381141A3 (de) | 1991-11-21 |
| AU4875990A (en) | 1990-08-09 |
| NO900432L (no) | 1990-08-01 |
| AR245694A1 (es) | 1994-02-28 |
| AU629290B2 (en) | 1992-10-01 |
| NZ232278A (en) | 1992-07-28 |
| ATE135702T1 (de) | 1996-04-15 |
| DE69025967T2 (de) | 1996-08-29 |
| CA2008616A1 (en) | 1990-07-31 |
| NO900432D0 (no) | 1990-01-30 |
| IL93187A0 (en) | 1990-11-05 |
| HUT53868A (en) | 1990-12-28 |
| FI900464A0 (fi) | 1990-01-30 |
| KR900011725A (ko) | 1990-08-02 |
| JP2841305B2 (ja) | 1998-12-24 |
| IL93187A (en) | 1994-12-29 |
| HU900592D0 (en) | 1990-04-28 |
| NO174887B (no) | 1994-04-18 |
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