IL90087A0 - Substituted-1-(1h-imidazol-4-yl)alkyl-benzamides,and salts thereof,their preparation and pharmaceutical compositions containing them - Google Patents

Substituted-1-(1h-imidazol-4-yl)alkyl-benzamides,and salts thereof,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL90087A0
IL90087A0 IL90087A IL9008789A IL90087A0 IL 90087 A0 IL90087 A0 IL 90087A0 IL 90087 A IL90087 A IL 90087A IL 9008789 A IL9008789 A IL 9008789A IL 90087 A0 IL90087 A0 IL 90087A0
Authority
IL
Israel
Prior art keywords
alkyl
imidazol
hydrogen
benzamides
salts
Prior art date
Application number
IL90087A
Other languages
English (en)
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of IL90087A0 publication Critical patent/IL90087A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Lubricants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
IL90087A 1988-04-28 1989-04-25 Substituted-1-(1h-imidazol-4-yl)alkyl-benzamides,and salts thereof,their preparation and pharmaceutical compositions containing them IL90087A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888810067A GB8810067D0 (en) 1988-04-28 1988-04-28 Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides

Publications (1)

Publication Number Publication Date
IL90087A0 true IL90087A0 (en) 1989-12-15

Family

ID=10636026

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90087A IL90087A0 (en) 1988-04-28 1989-04-25 Substituted-1-(1h-imidazol-4-yl)alkyl-benzamides,and salts thereof,their preparation and pharmaceutical compositions containing them

Country Status (30)

Country Link
US (1) US4923865A (ja)
EP (1) EP0341231B1 (ja)
JP (1) JP2840288B2 (ja)
KR (1) KR970011275B1 (ja)
AT (1) ATE82571T1 (ja)
AU (1) AU610796B2 (ja)
BR (2) BR1100052A (ja)
CA (1) CA1310966C (ja)
CY (1) CY1758A (ja)
DE (1) DE68903531T2 (ja)
DK (1) DK205589A (ja)
ES (1) ES2052969T3 (ja)
FI (1) FI101791B (ja)
GB (1) GB8810067D0 (ja)
GR (1) GR3006836T3 (ja)
HK (1) HK9494A (ja)
HU (1) HU203877B (ja)
IE (1) IE63698B1 (ja)
IL (1) IL90087A0 (ja)
LT (1) LT3671B (ja)
LV (1) LV10437B (ja)
MY (1) MY104084A (ja)
NO (1) NO173331C (ja)
NZ (1) NZ228897A (ja)
PH (1) PH25461A (ja)
PL (2) PL156250B1 (ja)
PT (1) PT90368B (ja)
RU (3) RU1830063C (ja)
UA (1) UA12835A1 (ja)
ZA (1) ZA893140B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9310965D0 (en) * 1993-05-27 1993-07-14 Ucb Sa 2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides
NZ276883A (en) * 1993-11-15 1998-08-26 Schering Corp 1h-imidazol-4-yl)alkyl]benzene derivatives
JP3294961B2 (ja) * 1993-12-10 2002-06-24 杏林製薬株式会社 新規イミダゾール誘導体及びその製造法
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
DE10161818A1 (de) * 2001-12-14 2003-06-26 Gruenenthal Gmbh Substituierte 1,5-Diaminopentan-3-ol-Verbindungen
CN101072561B (zh) * 2004-10-07 2011-05-11 生命医药公司 二氨基烷烃天冬氨酸蛋白酶抑制剂
TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
CL2007002689A1 (es) * 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100160424A1 (en) * 2007-06-20 2010-06-24 Baldwin John J Renin inhibitors
WO2009096996A1 (en) * 2007-06-20 2009-08-06 Smithkline Beecham Corporation Renin inhibitors
WO2009111685A1 (en) 2008-03-06 2009-09-11 Sensient Flavors Llc Herbal extracts and flavor systems for oral products and methods of making the same
US20110160300A1 (en) * 2008-06-20 2011-06-30 Marlys Hammond Renin Inhibitors and Methods of Use Thereof
WO2009158377A1 (en) * 2008-06-26 2009-12-30 Smith Kline Beecham Corporation Salts of methyl 2-((r))-(3-chlorophenyl)((r)-1-((s)-2-(methylamino)-3((r)-tetrahydro-2h-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
AR077692A1 (es) * 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
AU2012212323A1 (en) * 2011-02-01 2013-09-12 The Board Of Trustees Of The University Of Illinois HDAC inhibitors and therapeutic methods using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
US4303485A (en) 1979-08-20 1981-12-01 Minnesota Mining And Manufacturing Company Ultraviolet polymerization of acrylate monomers using oxidizable tin compounds
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
DE3635700A1 (de) 1986-10-21 1988-04-28 Michael Schmeller Hubeinrichtung
GB8626287D0 (en) * 1986-11-04 1986-12-03 Ucb Sa Substituted 1h-imidazoles
GB8714013D0 (en) * 1987-06-16 1987-07-22 Ici Plc (substituted-aralkyl)heterocyclic compounds

Also Published As

Publication number Publication date
RU1814647C (ru) 1993-05-07
JP2840288B2 (ja) 1998-12-24
DE68903531D1 (de) 1992-12-24
PT90368B (pt) 1994-08-31
IE891360L (en) 1989-10-28
IE63698B1 (en) 1995-05-31
RU1836353C (ru) 1993-08-23
LTIP827A (en) 1995-02-27
DK205589A (da) 1989-10-29
US4923865A (en) 1990-05-08
ATE82571T1 (de) 1992-12-15
HK9494A (en) 1994-02-09
BR1100052A (pt) 1999-12-07
AU610796B2 (en) 1991-05-23
EP0341231B1 (fr) 1992-11-19
HU203877B (en) 1991-10-28
PL161362B1 (pl) 1993-06-30
CA1310966C (en) 1992-12-01
DE68903531T2 (de) 1993-04-29
KR970011275B1 (ko) 1997-07-09
PL156250B1 (pl) 1992-02-28
UA12835A1 (uk) 1997-02-28
BR1100064A (pt) 1999-12-07
EP0341231A1 (fr) 1989-11-08
PT90368A (pt) 1989-11-10
NO891760L (no) 1989-10-30
CY1758A (en) 1994-07-15
GR3006836T3 (ja) 1993-06-30
FI101791B1 (fi) 1998-08-31
NO173331C (no) 1993-12-08
NO891760D0 (no) 1989-04-27
FI101791B (fi) 1998-08-31
ES2052969T3 (es) 1994-07-16
ZA893140B (en) 1990-01-31
AU3373089A (en) 1989-11-02
KR890016017A (ko) 1989-11-28
LV10437B (en) 1996-04-20
JPH01313467A (ja) 1989-12-18
HUT51257A (en) 1990-04-28
GB8810067D0 (en) 1988-06-02
LV10437A (lv) 1995-02-20
NZ228897A (en) 1990-08-28
FI891975A0 (fi) 1989-04-26
MY104084A (en) 1993-11-30
RU1830063C (ru) 1993-07-23
LT3671B (en) 1996-01-25
NO173331B (no) 1993-08-23
DK205589D0 (da) 1989-04-27
PH25461A (en) 1991-07-01
FI891975A (fi) 1989-10-29

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Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force