IL89185A - 5-halo-2-(omega-)(4-(2-pyrimidinyl)-1-piperazinyl(alkyl)thieno-(2.3-d)isothiazol-3(2h)-one 1,1-dioxides,their preparation and pharmaceutical compositions containing them - Google Patents
5-halo-2-(omega-)(4-(2-pyrimidinyl)-1-piperazinyl(alkyl)thieno-(2.3-d)isothiazol-3(2h)-one 1,1-dioxides,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL89185A IL89185A IL89185A IL8918589A IL89185A IL 89185 A IL89185 A IL 89185A IL 89185 A IL89185 A IL 89185A IL 8918589 A IL8918589 A IL 8918589A IL 89185 A IL89185 A IL 89185A
- Authority
- IL
- Israel
- Prior art keywords
- dioxides
- alkyl
- preparation
- isothiazol
- thieno
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT88390A ATA39088A (de) | 1988-02-18 | 1988-02-18 | Basisch substituierte thienoisothiazol-3(2h)-on-1,1-dioxide und ihre pharmazeutisch vertraeglichen salze, verfahren zu ihrer herstellung und ihre verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL89185A0 IL89185A0 (en) | 1989-09-10 |
IL89185A true IL89185A (en) | 1992-08-18 |
Family
ID=3489327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL89185A IL89185A (en) | 1988-02-18 | 1989-02-06 | 5-halo-2-(omega-)(4-(2-pyrimidinyl)-1-piperazinyl(alkyl)thieno-(2.3-d)isothiazol-3(2h)-one 1,1-dioxides,their preparation and pharmaceutical compositions containing them |
Country Status (28)
Country | Link |
---|---|
US (1) | US4929616A (no) |
EP (1) | EP0328913B1 (no) |
JP (1) | JPH01249779A (no) |
KR (1) | KR890013033A (no) |
CN (1) | CN1024798C (no) |
AT (2) | ATA39088A (no) |
AU (1) | AU618577B2 (no) |
CA (1) | CA1317956C (no) |
CS (1) | CS274578B2 (no) |
DD (1) | DD279021A5 (no) |
DE (1) | DE58907804D1 (no) |
DK (1) | DK170047B1 (no) |
EG (1) | EG20261A (no) |
ES (1) | ES2054887T3 (no) |
FI (1) | FI89491C (no) |
HR (1) | HRP940825A2 (no) |
HU (1) | HU201084B (no) |
IL (1) | IL89185A (no) |
LT (1) | LT3947B (no) |
MY (1) | MY103825A (no) |
NO (1) | NO176050C (no) |
NZ (1) | NZ227939A (no) |
PH (1) | PH26156A (no) |
SI (1) | SI8910358A (no) |
SU (1) | SU1729293A3 (no) |
UA (1) | UA13481A (no) |
YU (1) | YU35889A (no) |
ZA (1) | ZA891108B (no) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5071845A (en) * | 1988-12-28 | 1991-12-10 | Suntory Limited | Benzoxazepine derivative |
WO2005115992A1 (en) * | 2004-05-23 | 2005-12-08 | Housey Pharmaceuticals, Inc. | Theramutein modulators |
US8431110B2 (en) | 2005-05-23 | 2013-04-30 | Hmi Medical Innovations, Llc. | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators |
JP2009523408A (ja) * | 2005-11-23 | 2009-06-25 | ジェラルド・エム・ハウシー | タンパク質モジュレーターを同定、合成、最適化および解析する化合物群および方法群 |
CN101186612B (zh) * | 2006-11-15 | 2012-10-03 | 天津和美生物技术有限公司 | 可抑制细胞释放肿瘤坏死因子的吡咯啉衍生物及其制备和应用 |
US8551560B2 (en) * | 2008-05-23 | 2013-10-08 | Intermolecular, Inc. | Methods for improving selectivity of electroless deposition processes |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL47877A (en) | 1974-08-26 | 1978-10-31 | Sparamedica Ag | Thienothiazine carboxamide derivatives,their manufacture and pharmaceutical compositions containing them |
DE2534689B2 (de) | 1974-09-16 | 1979-03-01 | Basf Ag, 6700 Ludwigshafen | 23-Dihydro-3-oxo-thieno-isothiazol-1,1-dioxide |
LU78009A1 (de) | 1977-08-22 | 1979-05-23 | Hoffmann La Roche | Verfahren zur herstellung von thiazinderivaten |
AU518216B2 (en) | 1977-09-06 | 1981-09-17 | Hafslund Nycomed Pharma Aktiengesellschaft | Thienothiazine derivatives |
DE2839266A1 (de) | 1978-09-09 | 1980-03-20 | Thomae Gmbh Dr K | Kondensierte isothiazol-3(2h)-on-1,1- dioxide, verfahren zu deren herstellung und deren verwendung |
DE2749640A1 (de) | 1977-11-05 | 1979-05-10 | Thomae Gmbh Dr K | Ein thieno eckige klammer auf 3,2-d eckige klammer zu isothiazolondioxid, verfahren zu seiner herstellung und dessen verwendung |
AT364852B (de) * | 1977-11-05 | 1981-11-25 | Thomae Gmbh Dr K | Verfahren zur herstellung von kondensierten isothiazol-3(2h)-on-1,1-dioxiden und von deren salzen |
EP0103142B1 (de) | 1982-09-09 | 1987-04-22 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Thieno(2,3-e)-1,2-thiazin-Derivate |
DE3321969A1 (de) * | 1983-06-18 | 1984-12-20 | Troponwerke GmbH & Co KG, 5000 Köln | 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
FI862513A (fi) * | 1985-07-04 | 1987-01-05 | Chemie Linz Ag | Nya tieno-1,2-tiazolderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska preparat. |
US4675403A (en) * | 1985-10-16 | 1987-06-23 | American Home Products Corporation | 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity |
US4732984A (en) * | 1985-10-17 | 1988-03-22 | American Home Products Corporation | Piperazinoisothiazolones with psychotropic activity |
-
1988
- 1988-02-18 AT AT88390A patent/ATA39088A/de not_active IP Right Cessation
-
1989
- 1989-01-26 AT AT89101335T patent/ATE106888T1/de active
- 1989-01-26 DE DE58907804T patent/DE58907804D1/de not_active Expired - Fee Related
- 1989-01-26 EP EP89101335A patent/EP0328913B1/de not_active Expired - Lifetime
- 1989-01-26 ES ES89101335T patent/ES2054887T3/es not_active Expired - Lifetime
- 1989-02-06 US US07/306,744 patent/US4929616A/en not_active Expired - Fee Related
- 1989-02-06 IL IL89185A patent/IL89185A/xx not_active IP Right Cessation
- 1989-02-07 CA CA000590351A patent/CA1317956C/en not_active Expired - Fee Related
- 1989-02-10 NZ NZ227939A patent/NZ227939A/xx unknown
- 1989-02-13 CS CS93189A patent/CS274578B2/cs unknown
- 1989-02-13 ZA ZA891108A patent/ZA891108B/xx unknown
- 1989-02-14 FI FI890690A patent/FI89491C/fi not_active IP Right Cessation
- 1989-02-14 EG EG7289A patent/EG20261A/xx active
- 1989-02-15 AU AU29945/89A patent/AU618577B2/en not_active Ceased
- 1989-02-15 PH PH38203A patent/PH26156A/en unknown
- 1989-02-16 DD DD89325819A patent/DD279021A5/de unknown
- 1989-02-16 SI SI8910358A patent/SI8910358A/sl unknown
- 1989-02-16 MY MYPI89000193A patent/MY103825A/en unknown
- 1989-02-16 YU YU00358/89A patent/YU35889A/xx unknown
- 1989-02-16 KR KR1019890001758A patent/KR890013033A/ko not_active Application Discontinuation
- 1989-02-17 SU SU894613473A patent/SU1729293A3/ru active
- 1989-02-17 JP JP1036407A patent/JPH01249779A/ja active Pending
- 1989-02-17 DK DK073289A patent/DK170047B1/da not_active IP Right Cessation
- 1989-02-17 HU HU89810A patent/HU201084B/hu not_active IP Right Cessation
- 1989-02-17 NO NO890691A patent/NO176050C/no unknown
- 1989-02-17 CN CN89102110A patent/CN1024798C/zh not_active Expired - Fee Related
- 1989-02-17 UA UA4613473A patent/UA13481A/uk unknown
-
1994
- 1994-01-27 LT LTIP1813A patent/LT3947B/lt not_active IP Right Cessation
- 1994-10-26 HR HR940825A patent/HRP940825A2/xx not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |