IL84657A - 3-(substituted methyl)-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
3-(substituted methyl)-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL84657A IL84657A IL84657A IL8465787A IL84657A IL 84657 A IL84657 A IL 84657A IL 84657 A IL84657 A IL 84657A IL 8465787 A IL8465787 A IL 8465787A IL 84657 A IL84657 A IL 84657A
- Authority
- IL
- Israel
- Prior art keywords
- substituted
- alkyl
- unsubstituted
- derivatives
- piperidyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8616795A FR2607503B1 (fr) | 1986-12-02 | 1986-12-02 | Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
IL84657A0 IL84657A0 (en) | 1988-04-29 |
IL84657A true IL84657A (en) | 1991-09-16 |
Family
ID=9341442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL84657A IL84657A (en) | 1986-12-02 | 1987-11-29 | 3-(substituted methyl)-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (23)
Country | Link |
---|---|
US (1) | US4960779A (ko) |
EP (1) | EP0274930B1 (ko) |
JP (1) | JP2531710B2 (ko) |
KR (1) | KR960011775B1 (ko) |
AT (1) | ATE66480T1 (ko) |
AU (1) | AU600776B2 (ko) |
CA (1) | CA1298296C (ko) |
DE (1) | DE3772369D1 (ko) |
DK (1) | DK168383B1 (ko) |
ES (1) | ES2029282T3 (ko) |
FI (1) | FI84722C (ko) |
FR (1) | FR2607503B1 (ko) |
GR (1) | GR3002576T3 (ko) |
HU (1) | HU198047B (ko) |
IE (1) | IE61088B1 (ko) |
IL (1) | IL84657A (ko) |
MA (1) | MA21117A1 (ko) |
MX (1) | MX9560A (ko) |
NO (1) | NO166036C (ko) |
NZ (1) | NZ222751A (ko) |
PT (1) | PT86260B (ko) |
SU (2) | SU1577698A3 (ko) |
ZA (1) | ZA879000B (ko) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2607506B1 (fr) * | 1986-12-02 | 1989-01-06 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2607504B1 (fr) * | 1986-12-02 | 1989-01-27 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5273978A (en) * | 1991-07-10 | 1993-12-28 | Takeda Chemical Industries, Ltd. | Optically active isoindoline derivatives, their production and use |
FR2678931B1 (fr) * | 1991-07-12 | 1993-09-24 | Rhone Poulenc Rorer Sa | Nouveau derive de l'amino-2 naphtyridine, sa preparation et son emploi. |
FR2678933B1 (fr) * | 1991-07-12 | 1993-09-24 | Rhone Poulenc Rorer Sa | Procede de preparation des isomeres optiques d'un derive de l'amino-2 naphtyridine. |
FR2678932B1 (fr) * | 1991-07-12 | 1993-09-24 | Rhone Poulenc Rorer Sa | Procede de preparation des isomeres optiques d'un derive de l'amino-2 naphtyridine. |
FR2678934B1 (fr) * | 1991-07-12 | 1995-01-13 | Rhone Poulenc Rorer Sa | Procede de preparation de l'isomere dextrogyre d'un derive de l'isoindolinone. |
FR2684673B1 (fr) * | 1991-12-04 | 1994-01-21 | Rhone Poulenc Rorer Sa | Procede de preparation d'un derive de l'amino-2 naphtyridine racemique. |
FR2685330B1 (fr) * | 1991-12-20 | 1994-02-04 | Rhone Poulenc Rorer Sa | Procede de preparation des enantiomeres d'un derive de l'isoindolinone. |
FR2687154B1 (fr) * | 1992-02-07 | 1995-05-12 | Rhone Poulenc Rorer Sa | Nouveau derive de l'isoindolinone, sa preparation et les compositions pharmaceutiques qui le contiennent. |
FR2695389B1 (fr) * | 1992-09-08 | 1994-11-04 | Rhone Poulenc Rorer Sa | Nouveau dérivé de l'isoindolinone, sa préparation et les compositions pharmaceutiques qui le contiennent. |
US5498716A (en) * | 1994-01-12 | 1996-03-12 | Rhone-Poulenc Rorer S.A. | 2-amino naphthyridine derivative, its preparation and its use |
US6399553B1 (en) | 1997-06-05 | 2002-06-04 | The Clorox Company | Reduced residue hard surface cleaner |
AU6381000A (en) * | 1999-07-29 | 2001-02-19 | Interneuron Pharmaceuticals, Inc. | Methods and compositions for alleviating stuttering |
US6855721B1 (en) | 2000-07-28 | 2005-02-15 | Indevus Pharmaceuticals, Inc. | Methods and compositions for alleviating stuttering |
AU783516B2 (en) | 2001-04-30 | 2005-11-03 | Warner-Lambert Company | Methods, kits and compositions for using pyrrole derivatives |
AU2003212585B2 (en) | 2002-03-29 | 2009-02-26 | Endo Pharmaceuticals Solutions Inc. | Methods of preparation of the 2-(7-chloro-1,8-naphthyridine-2YL)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinone |
WO2005105061A2 (en) * | 2004-04-14 | 2005-11-10 | Indevus Pharmaceuticals, Inc. | Transdermal patch |
JP2014506603A (ja) | 2011-02-25 | 2014-03-17 | コンサート ファーマシューティカルズ インコーポレイテッド | 2−アミノ−ナフチリジン誘導体 |
CN112138003A (zh) * | 2019-06-27 | 2020-12-29 | 中山大学 | 3-正丁基-异吲哚啉-1-酮在镇静、抗惊厥和抗癫痫的药物中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE793851A (fr) * | 1972-01-10 | 1973-07-10 | Rhone Poulenc Sa | Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent |
US4244966A (en) * | 1979-09-24 | 1981-01-13 | American Home Products Corporation | 1,3-Dihydro-3-(2-hydroxy-, 2-bromo- or 2-chloroethyl)-2H-isoindol-1-one derivatives |
DE3378763D1 (en) * | 1982-04-02 | 1989-02-02 | Takeda Chemical Industries Ltd | Condensed pyrrolinone derivatives, and their production |
WO1984003089A1 (en) * | 1983-02-05 | 1984-08-16 | Takeda Chemical Industries Ltd | Condensed pyrrolinone derivatives |
JPS6169773A (ja) * | 1984-09-14 | 1986-04-10 | Takeda Chem Ind Ltd | イソインドリノン誘導体 |
US4657913A (en) * | 1985-04-18 | 1987-04-14 | Warner-Lambert Company | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents |
FR2607506B1 (fr) * | 1986-12-02 | 1989-01-06 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2607504B1 (fr) * | 1986-12-02 | 1989-01-27 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
-
1986
- 1986-12-02 FR FR8616795A patent/FR2607503B1/fr not_active Expired
-
1987
- 1987-11-27 MA MA21358A patent/MA21117A1/fr unknown
- 1987-11-29 IL IL84657A patent/IL84657A/xx unknown
- 1987-11-30 AU AU81911/87A patent/AU600776B2/en not_active Expired
- 1987-11-30 ZA ZA879000A patent/ZA879000B/xx unknown
- 1987-11-30 IE IE325187A patent/IE61088B1/en not_active IP Right Cessation
- 1987-11-30 NZ NZ222751A patent/NZ222751A/xx unknown
- 1987-12-01 NO NO875011A patent/NO166036C/no unknown
- 1987-12-01 DK DK630687A patent/DK168383B1/da not_active IP Right Cessation
- 1987-12-01 KR KR1019870013648A patent/KR960011775B1/ko not_active IP Right Cessation
- 1987-12-01 DE DE8787402707T patent/DE3772369D1/de not_active Expired - Lifetime
- 1987-12-01 SU SU874203784A patent/SU1577698A3/ru active
- 1987-12-01 AT AT87402707T patent/ATE66480T1/de not_active IP Right Cessation
- 1987-12-01 FI FI875298A patent/FI84722C/fi not_active IP Right Cessation
- 1987-12-01 EP EP87402707A patent/EP0274930B1/fr not_active Expired - Lifetime
- 1987-12-01 ES ES198787402707T patent/ES2029282T3/es not_active Expired - Lifetime
- 1987-12-01 CA CA000553253A patent/CA1298296C/fr not_active Expired - Lifetime
- 1987-12-01 HU HU875397A patent/HU198047B/hu not_active IP Right Cessation
- 1987-12-01 MX MX956087A patent/MX9560A/es unknown
- 1987-12-02 PT PT86260A patent/PT86260B/pt unknown
- 1987-12-02 JP JP62303419A patent/JP2531710B2/ja not_active Expired - Lifetime
-
1989
- 1989-01-13 SU SU894613217A patent/SU1630612A3/ru active
- 1989-06-01 US US07/360,122 patent/US4960779A/en not_active Expired - Lifetime
-
1991
- 1991-08-22 GR GR91400331T patent/GR3002576T3/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL84657A (en) | 3-(substituted methyl)-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing them | |
AU594538B2 (en) | New pyrrole derivatives, their preparation and pharmaceutical compositions which contain them | |
IL84658A (en) | Esters of 3-hydroxy-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing the same |