NO166036C - Analogifremgangsmaate for fremstilling av nye terapeutisk aktive naftyridinderivater. - Google Patents

Analogifremgangsmaate for fremstilling av nye terapeutisk aktive naftyridinderivater.

Info

Publication number
NO166036C
NO166036C NO875011A NO875011A NO166036C NO 166036 C NO166036 C NO 166036C NO 875011 A NO875011 A NO 875011A NO 875011 A NO875011 A NO 875011A NO 166036 C NO166036 C NO 166036C
Authority
NO
Norway
Prior art keywords
alkyl
unsubstituted
substituted
piperidyl
pyrrolidinyl
Prior art date
Application number
NO875011A
Other languages
English (en)
Other versions
NO875011D0 (no
NO875011L (no
NO166036B (no
Inventor
Jean-Dominique Bourzat
Marc Capet
Claude Cotrel
Richard Labaudiniere
Philippe Pitchen
Gerard Roussel
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of NO875011D0 publication Critical patent/NO875011D0/no
Publication of NO875011L publication Critical patent/NO875011L/no
Publication of NO166036B publication Critical patent/NO166036B/no
Publication of NO166036C publication Critical patent/NO166036C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
NO875011A 1986-12-02 1987-12-01 Analogifremgangsmaate for fremstilling av nye terapeutisk aktive naftyridinderivater. NO166036C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8616795A FR2607503B1 (fr) 1986-12-02 1986-12-02 Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (4)

Publication Number Publication Date
NO875011D0 NO875011D0 (no) 1987-12-01
NO875011L NO875011L (no) 1988-06-03
NO166036B NO166036B (no) 1991-02-11
NO166036C true NO166036C (no) 1991-05-22

Family

ID=9341442

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875011A NO166036C (no) 1986-12-02 1987-12-01 Analogifremgangsmaate for fremstilling av nye terapeutisk aktive naftyridinderivater.

Country Status (23)

Country Link
US (1) US4960779A (no)
EP (1) EP0274930B1 (no)
JP (1) JP2531710B2 (no)
KR (1) KR960011775B1 (no)
AT (1) ATE66480T1 (no)
AU (1) AU600776B2 (no)
CA (1) CA1298296C (no)
DE (1) DE3772369D1 (no)
DK (1) DK168383B1 (no)
ES (1) ES2029282T3 (no)
FI (1) FI84722C (no)
FR (1) FR2607503B1 (no)
GR (1) GR3002576T3 (no)
HU (1) HU198047B (no)
IE (1) IE61088B1 (no)
IL (1) IL84657A (no)
MA (1) MA21117A1 (no)
MX (1) MX9560A (no)
NO (1) NO166036C (no)
NZ (1) NZ222751A (no)
PT (1) PT86260B (no)
SU (2) SU1577698A3 (no)
ZA (1) ZA879000B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
US5273978A (en) * 1991-07-10 1993-12-28 Takeda Chemical Industries, Ltd. Optically active isoindoline derivatives, their production and use
FR2678933B1 (fr) * 1991-07-12 1993-09-24 Rhone Poulenc Rorer Sa Procede de preparation des isomeres optiques d'un derive de l'amino-2 naphtyridine.
FR2678931B1 (fr) * 1991-07-12 1993-09-24 Rhone Poulenc Rorer Sa Nouveau derive de l'amino-2 naphtyridine, sa preparation et son emploi.
FR2678934B1 (fr) * 1991-07-12 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de l'isomere dextrogyre d'un derive de l'isoindolinone.
FR2678932B1 (fr) * 1991-07-12 1993-09-24 Rhone Poulenc Rorer Sa Procede de preparation des isomeres optiques d'un derive de l'amino-2 naphtyridine.
FR2684673B1 (fr) * 1991-12-04 1994-01-21 Rhone Poulenc Rorer Sa Procede de preparation d'un derive de l'amino-2 naphtyridine racemique.
FR2685330B1 (fr) * 1991-12-20 1994-02-04 Rhone Poulenc Rorer Sa Procede de preparation des enantiomeres d'un derive de l'isoindolinone.
FR2687154B1 (fr) * 1992-02-07 1995-05-12 Rhone Poulenc Rorer Sa Nouveau derive de l'isoindolinone, sa preparation et les compositions pharmaceutiques qui le contiennent.
FR2695389B1 (fr) * 1992-09-08 1994-11-04 Rhone Poulenc Rorer Sa Nouveau dérivé de l'isoindolinone, sa préparation et les compositions pharmaceutiques qui le contiennent.
US5498716A (en) * 1994-01-12 1996-03-12 Rhone-Poulenc Rorer S.A. 2-amino naphthyridine derivative, its preparation and its use
US6399553B1 (en) 1997-06-05 2002-06-04 The Clorox Company Reduced residue hard surface cleaner
WO2001008670A2 (en) * 1999-07-29 2001-02-08 Interneuron Pharmaceuticals, Inc. Methods and compositions for alleviating stuttering
US6855721B1 (en) * 2000-07-28 2005-02-15 Indevus Pharmaceuticals, Inc. Methods and compositions for alleviating stuttering
AU783516B2 (en) 2001-04-30 2005-11-03 Warner-Lambert Company Methods, kits and compositions for using pyrrole derivatives
DK1490363T3 (da) * 2002-03-29 2006-05-15 Indevus Pharmaceuticals Inc Fremgangsmåder til fremstilling af 2-7-chlor-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxo-hexyl)1-isoindolinon
WO2005105061A2 (en) * 2004-04-14 2005-11-10 Indevus Pharmaceuticals, Inc. Transdermal patch
JP2014506603A (ja) 2011-02-25 2014-03-17 コンサート ファーマシューティカルズ インコーポレイテッド ２−アミノ−ナフチリジン誘導体
CN112138003A (zh) * 2019-06-27 2020-12-29 中山大学 3-正丁基-异吲哚啉-1-酮在镇静、抗惊厥和抗癫痫的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793851A (fr) * 1972-01-10 1973-07-10 Rhone Poulenc Sa Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent
US4244966A (en) * 1979-09-24 1981-01-13 American Home Products Corporation 1,3-Dihydro-3-(2-hydroxy-, 2-bromo- or 2-chloroethyl)-2H-isoindol-1-one derivatives
DE3378763D1 (en) * 1982-04-02 1989-02-02 Takeda Chemical Industries Ltd Condensed pyrrolinone derivatives, and their production
WO1984003089A1 (en) * 1983-02-05 1984-08-16 Takeda Chemical Industries Ltd Condensed pyrrolinone derivatives
JPS6169773A (ja) * 1984-09-14 1986-04-10 Takeda Chem Ind Ltd イソインドリノン誘導体
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
SU1577698A3 (ru) 1990-07-07
CA1298296C (fr) 1992-03-31
FI84722C (fi) 1992-01-10
ZA879000B (en) 1988-06-01
FI875298A (fi) 1988-06-03
JPS63154681A (ja) 1988-06-27
NZ222751A (en) 1989-10-27
FR2607503A1 (fr) 1988-06-03
IL84657A (en) 1991-09-16
PT86260A (fr) 1988-01-01
FI84722B (fi) 1991-09-30
GR3002576T3 (en) 1993-01-25
DK168383B1 (da) 1994-03-21
MX9560A (es) 1993-11-01
ATE66480T1 (de) 1991-09-15
MA21117A1 (fr) 1988-07-01
HU198047B (en) 1989-07-28
PT86260B (pt) 1990-11-07
JP2531710B2 (ja) 1996-09-04
KR960011775B1 (ko) 1996-08-30
DK630687D0 (da) 1987-12-01
DK630687A (da) 1988-06-03
AU600776B2 (en) 1990-08-23
IL84657A0 (en) 1988-04-29
NO875011D0 (no) 1987-12-01
DE3772369D1 (de) 1991-09-26
FI875298A0 (fi) 1987-12-01
US4960779A (en) 1990-10-02
NO875011L (no) 1988-06-03
IE873251L (en) 1988-06-02
IE61088B1 (en) 1994-09-21
FR2607503B1 (fr) 1989-02-24
HUT46001A (en) 1988-09-28
EP0274930A1 (fr) 1988-07-20
ES2029282T3 (es) 1992-08-01
AU8191187A (en) 1988-06-02
SU1630612A3 (ru) 1991-02-23
KR880007516A (ko) 1988-08-27
EP0274930B1 (fr) 1991-08-21
NO166036B (no) 1991-02-11

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