IL83691A - Acylated quinolinamines, their preparation and pharmaceutical compositions containing them - Google Patents

Acylated quinolinamines, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL83691A
IL83691A IL83691A IL8369187A IL83691A IL 83691 A IL83691 A IL 83691A IL 83691 A IL83691 A IL 83691A IL 8369187 A IL8369187 A IL 8369187A IL 83691 A IL83691 A IL 83691A
Authority
IL
Israel
Prior art keywords
6alkyl
phenyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL83691A
Other languages
English (en)
Inventor
John Ife Robert
Henry Brown Thomas
Andrew Leach Colin
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL83691A publication Critical patent/IL83691A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL83691A 1986-09-05 1987-08-31 Acylated quinolinamines, their preparation and pharmaceutical compositions containing them IL83691A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868621425A GB8621425D0 (en) 1986-09-05 1986-09-05 Compounds

Publications (1)

Publication Number Publication Date
IL83691A true IL83691A (en) 1993-08-18

Family

ID=10603729

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83691A IL83691A (en) 1986-09-05 1987-08-31 Acylated quinolinamines, their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
US (2) US4806549A (fi)
EP (1) EP0259174B1 (fi)
JP (1) JPH07602B2 (fi)
KR (1) KR950013850B1 (fi)
CN (1) CN1019802B (fi)
AT (1) ATE73776T1 (fi)
AU (1) AU598299B2 (fi)
CA (1) CA1308106C (fi)
CZ (1) CZ398291A3 (fi)
DE (1) DE3777505D1 (fi)
DK (1) DK159308C (fi)
EG (1) EG18408A (fi)
ES (1) ES2033316T3 (fi)
FI (1) FI88919C (fi)
GB (1) GB8621425D0 (fi)
GR (1) GR3004692T3 (fi)
HU (1) HU199804B (fi)
IE (1) IE61104B1 (fi)
IL (1) IL83691A (fi)
MX (1) MX9203550A (fi)
MY (1) MY102689A (fi)
NO (1) NO172388C (fi)
NZ (1) NZ221663A (fi)
PH (1) PH23695A (fi)
PT (1) PT85651B (fi)
WO (1) WO1988001621A1 (fi)
ZA (1) ZA876581B (fi)
ZW (1) ZW16787A1 (fi)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5049567A (en) * 1988-02-25 1991-09-17 Smithkline Beckman Intercredit B.V. Substituted 4-aminoquinazoline derivatives and method of use
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632305B1 (fr) * 1988-06-06 1992-05-15 Sanofi Sa Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
EP0480052B1 (en) * 1990-03-28 1998-01-14 Otsuka Pharmaceutical Co., Ltd. Quinoline derivative, antiulcer drug containing the same, and production of said derivative
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
SE9302005D0 (sv) 1993-06-11 1993-06-11 Ab Astra New active compounds
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
IN188411B (fi) * 1997-03-27 2002-09-21 Yuhan Corp
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
GB2396815B (en) * 1999-10-27 2004-09-08 Phytopharm Plc A composition comprising a pregnenone derivative and an NSAID
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
CA2467652A1 (en) * 2001-11-19 2003-05-30 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CN1652822A (zh) * 2002-05-07 2005-08-10 奥坦纳医药公司 用于治疗气道病症的可逆质子泵抑制剂和气道治疗剂的新组合
AU2003254282A1 (en) * 2002-08-01 2004-02-23 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
EP1606261B1 (en) 2003-03-10 2009-11-04 Nycomed GmbH Novel process for the preparation of roflumilast
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
SE0400284D0 (sv) * 2004-02-10 2004-02-10 Astrazeneca Ab Novel compounds
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
WO2008012621A2 (en) 2006-07-25 2008-01-31 Vecta, Ltd. Compositions and meth0ds for inhibiting gastric acide secretion using derivatives of small dicarboxylic acids in combination with ppi
EP2486910A3 (en) 2006-10-27 2012-08-22 The Curators Of The University Of Missouri Multi-chambered apparatus comprising a dispenser head
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
CL2008000191A1 (es) * 2007-01-25 2008-08-22 Astrazeneca Ab Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
CN101980700A (zh) 2008-02-20 2011-02-23 密苏里大学董事会 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法
EP2310375A1 (en) * 2008-05-07 2011-04-20 AstraZeneca AB Chemical compounds
US8247280B2 (en) 2009-10-20 2012-08-21 Taiwan Semiconductor Manufacturing Company, Ltd. Integration of low and high voltage CMOS devices
US20210177827A1 (en) * 2017-10-25 2021-06-17 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
EP0193329A3 (en) * 1985-02-22 1987-08-19 Beecham Group Plc Pyrazolopyridines, their preparation and pharmaceutical compositions containing them
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Also Published As

Publication number Publication date
WO1988001621A1 (en) 1988-03-10
PT85651A (en) 1987-10-01
EP0259174B1 (en) 1992-03-18
CA1308106C (en) 1992-09-29
GR3004692T3 (fi) 1993-04-28
NO172388C (no) 1993-07-14
CN1019802B (zh) 1992-12-30
DK245888A (da) 1988-05-05
IE872370L (en) 1988-03-05
MY102689A (en) 1992-09-30
ZA876581B (en) 1989-04-26
ES2033316T3 (es) 1993-03-16
HU199804B (en) 1990-03-28
GB8621425D0 (en) 1986-10-15
NZ221663A (en) 1989-08-29
ATE73776T1 (de) 1992-04-15
AU598299B2 (en) 1990-06-21
ZW16787A1 (en) 1988-05-25
CZ398291A3 (en) 1994-02-16
FI88919B (fi) 1993-04-15
NO881940D0 (no) 1988-05-04
KR950013850B1 (ko) 1995-11-17
PT85651B (pt) 1990-05-31
EP0259174A1 (en) 1988-03-09
EG18408A (en) 1993-02-28
US4806550A (en) 1989-02-21
PH23695A (en) 1989-09-27
HUT47913A (en) 1989-04-28
JPH01500664A (ja) 1989-03-09
MX9203550A (es) 1992-09-01
FI882089A0 (fi) 1988-05-04
DK245888D0 (da) 1988-05-05
US4806549A (en) 1989-02-21
FI88919C (fi) 1993-07-26
NO172388B (no) 1993-04-05
NO881940L (no) 1988-05-04
DE3777505D1 (de) 1992-04-23
KR880701711A (ko) 1988-11-04
DK159308B (da) 1990-10-01
DK159308C (da) 1991-03-11
CN87106163A (zh) 1988-03-16
JPH07602B2 (ja) 1995-01-11
IE61104B1 (en) 1994-10-05
FI882089A (fi) 1988-05-04
AU7874187A (en) 1988-03-24

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Legal Events

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RH Patent void