IL82982A - Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides - Google Patents

Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides

Info

Publication number
IL82982A
IL82982A IL82982A IL8298287A IL82982A IL 82982 A IL82982 A IL 82982A IL 82982 A IL82982 A IL 82982A IL 8298287 A IL8298287 A IL 8298287A IL 82982 A IL82982 A IL 82982A
Authority
IL
Israel
Prior art keywords
phenylimidazo
acetamides
pyridine
alkyl
preparation
Prior art date
Application number
IL82982A
Other languages
English (en)
Other versions
IL82982A0 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL82982A0 publication Critical patent/IL82982A0/xx
Publication of IL82982A publication Critical patent/IL82982A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
IL82982A 1986-06-27 1987-06-24 Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides IL82982A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8609330A FR2600650B1 (fr) 1986-06-27 1986-06-27 Procede de preparation d'imidazopyridines et composes intermediaires

Publications (2)

Publication Number Publication Date
IL82982A0 IL82982A0 (en) 1987-12-20
IL82982A true IL82982A (en) 1992-03-29

Family

ID=9336785

Family Applications (1)

Application Number Title Priority Date Filing Date
IL82982A IL82982A (en) 1986-06-27 1987-06-24 Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides

Country Status (21)

Country Link
US (1) US4794185A (no)
EP (1) EP0251859B1 (no)
JP (1) JPH0653740B2 (no)
KR (1) KR940006594B1 (no)
AR (1) AR243188A1 (no)
AT (1) ATE58537T1 (no)
AU (1) AU7477287A (no)
CA (1) CA1324138C (no)
DE (1) DE3766300D1 (no)
DK (1) DK169505B1 (no)
ES (1) ES2019646B3 (no)
FI (1) FI872850A (no)
FR (1) FR2600650B1 (no)
GR (1) GR3001118T3 (no)
HU (1) HU204826B (no)
IE (1) IE60467B1 (no)
IL (1) IL82982A (no)
NO (1) NO167392C (no)
NZ (1) NZ220853A (no)
PT (1) PT85188B (no)
ZA (1) ZA874643B (no)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0234970B1 (fr) * 1986-01-22 1991-04-17 Synthelabo Dérivés d'acylaminométhyl-3 imidazo[1,2-a]pyridines, leur préparation et leur application en thérapeutique
FR2615513B1 (fr) * 1987-05-21 1989-07-13 Synthelabo Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
WO1999063977A2 (en) 1998-06-09 1999-12-16 Takeda Chemical Industries, Ltd. Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone, triazolam and brotizolam for treating or preventing sleep disorders
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
DE60020814T2 (de) * 1999-03-25 2006-05-04 Synthon B.V. Zolpidem salze
SI1038875T1 (en) 1999-03-25 2003-12-31 Synthon B.V. Imidazopyridine derivatives and process for making them
US6333345B1 (en) * 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) * 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
AU5066101A (en) 2000-04-13 2001-10-30 Synthon B.V. Modified release formulations containing a hypnotic agent
YU79402A (sh) * 2000-04-24 2006-03-03 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrat
EP1604663A1 (en) * 2000-04-24 2005-12-14 Teva Pharmaceutical Industries Ltd Zolpidem Hemitartrate Form H Solvate
IT1318624B1 (it) * 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
AU2000264428A1 (en) * 2000-08-17 2002-02-25 Cilag A.G. Process for the preparation of imidazopyridines
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
DE10121638A1 (de) * 2001-05-03 2002-11-14 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Imidazopyridinen
US20020183522A1 (en) 2001-05-03 2002-12-05 Markus Sauter Process for preparing zolpidem
ATE394398T1 (de) * 2002-07-15 2008-05-15 Scinopharm Taiwan Ltd Verfahren zur herstellung von imidazo(1,2- a)pyridin-3-acetamiden
EP1575952B1 (en) * 2002-12-18 2009-02-18 Mallinckrodt Inc. Synthesis of heteroaryl acetamides
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
GB0311457D0 (en) * 2003-05-19 2003-06-25 Sciencom Ltd New therapeutic use
ES2515092T3 (es) 2003-12-11 2014-10-29 Sunovion Pharmaceuticals Inc. Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión
JP2008503578A (ja) * 2004-06-22 2008-02-07 マリンクロッド・インコーポレイテッド 水分含量を減少させた反応混合物からのヘテロアリールアセトアミドの合成
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
CN101277959A (zh) * 2005-10-03 2008-10-01 马林克罗特公司 制备唑吡坦半酒石酸盐和酒石酸盐多晶型的方法
CN101291654A (zh) * 2005-10-17 2008-10-22 马林克罗特公司 片剂基质中唑吡坦的多晶型转化
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
EP1948132B1 (en) 2005-11-18 2009-08-05 Synhton B.V. Zolpidem tablets
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
US7998971B2 (en) * 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
KR101704589B1 (ko) * 2016-07-12 2017-02-08 주식회사 뉴트라팜텍 후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물
CN107793415A (zh) * 2016-12-01 2018-03-13 湖南省食品药品检验研究院 酒石酸唑吡坦杂质的合成方法
CN106749237A (zh) * 2016-12-28 2017-05-31 江苏豪森药业集团有限公司 酒石酸唑吡坦及其中间体的制备方法
CN114057725B (zh) * 2020-07-31 2024-01-16 株洲千金药业股份有限公司 一种酒石酸唑吡坦的合成方法
CN114057727B (zh) * 2020-07-31 2024-02-27 株洲千金药业股份有限公司 一种唑吡坦中间体的合成方法
CN114057726A (zh) * 2020-07-31 2022-02-18 株洲千金药业股份有限公司 一种唑吡坦盐酸盐的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68765B (no) * 1979-06-20 1982-02-17 Rohm & Haas
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
FI872850A (fi) 1987-12-28
DK169505B1 (da) 1994-11-14
US4794185A (en) 1988-12-27
EP0251859B1 (fr) 1990-11-22
JPH0653740B2 (ja) 1994-07-20
NO872682L (no) 1987-12-28
PT85188B (pt) 1990-03-30
NO167392B (no) 1991-07-22
HU204826B (en) 1992-02-28
FR2600650A1 (fr) 1987-12-31
KR880000433A (ko) 1988-03-25
KR940006594B1 (ko) 1994-07-23
IE871723L (en) 1987-12-27
NZ220853A (en) 1989-09-27
AR243188A1 (es) 1993-07-30
IL82982A0 (en) 1987-12-20
CA1324138C (en) 1993-11-09
DK328187D0 (da) 1987-06-26
NO167392C (no) 1991-10-30
JPS638384A (ja) 1988-01-14
IE60467B1 (en) 1994-07-13
AU7477287A (en) 1988-01-07
EP0251859A2 (fr) 1988-01-07
PT85188A (fr) 1987-07-01
DK328187A (da) 1987-12-28
EP0251859A3 (en) 1989-07-19
ES2019646B3 (es) 1991-07-01
DE3766300D1 (de) 1991-01-03
FR2600650B1 (fr) 1988-09-09
HUT44547A (en) 1988-03-28
ZA874643B (en) 1988-02-24
GR3001118T3 (en) 1992-05-12
FI872850A0 (fi) 1987-06-26
NO872682D0 (no) 1987-06-26
ATE58537T1 (de) 1990-12-15

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