IL80947A - 9-(hydroxyalkoxy)-9h-purin-2-amine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

9-(hydroxyalkoxy)-9h-purin-2-amine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL80947A
IL80947A IL80947A IL8094786A IL80947A IL 80947 A IL80947 A IL 80947A IL 80947 A IL80947 A IL 80947A IL 8094786 A IL8094786 A IL 8094786A IL 80947 A IL80947 A IL 80947A
Authority
IL
Israel
Prior art keywords
hydrogen
preparation
ch2oh
hydroxyalkoxy
purin
Prior art date
Application number
IL80947A
Other languages
English (en)
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858530813A external-priority patent/GB8530813D0/en
Priority claimed from GB868603228A external-priority patent/GB8603228D0/en
Priority claimed from GB868620849A external-priority patent/GB8620849D0/en
Priority claimed from GB868626041A external-priority patent/GB8626041D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of IL80947A publication Critical patent/IL80947A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Sub-Exchange Stations And Push- Button Telephones (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Nonmetallic Welding Materials (AREA)
  • General Factory Administration (AREA)
  • Jib Cranes (AREA)
  • Cephalosporin Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL80947A 1985-12-13 1986-12-11 9-(hydroxyalkoxy)-9h-purin-2-amine derivatives,their preparation and pharmaceutical compositions containing them IL80947A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858530813A GB8530813D0 (en) 1985-12-13 1985-12-13 Compounds
GB868603228A GB8603228D0 (en) 1986-02-10 1986-02-10 Compounds
GB868620849A GB8620849D0 (en) 1986-08-28 1986-08-28 Compounds
GB868626041A GB8626041D0 (en) 1986-10-31 1986-10-31 Compounds

Publications (1)

Publication Number Publication Date
IL80947A true IL80947A (en) 1990-01-18

Family

ID=27449713

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80947A IL80947A (en) 1985-12-13 1986-12-11 9-(hydroxyalkoxy)-9h-purin-2-amine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
EP (1) EP0242482B1 (de)
JP (1) JPH085886B2 (de)
KR (1) KR940010033B1 (de)
AT (1) ATE127466T1 (de)
AU (1) AU599066B2 (de)
CA (1) CA1296726C (de)
DE (1) DE3650384T2 (de)
DK (1) DK166823B1 (de)
ES (1) ES2076139T3 (de)
FI (1) FI85143C (de)
GR (1) GR3018105T3 (de)
HU (1) HU200461B (de)
IL (1) IL80947A (de)
MA (1) MA20828A1 (de)
MY (1) MY101126A (de)
NO (1) NO166226C (de)
NZ (1) NZ218598A (de)
PL (3) PL150926B1 (de)
PT (1) PT83911B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8602346D0 (en) * 1986-01-30 1986-03-05 Wellcome Found Antiviral combinations
US4965270A (en) * 1987-05-30 1990-10-23 Beecham Group P.L.C. Purine derivatives
GB8712744D0 (en) * 1987-05-30 1987-07-01 Beecham Group Plc Active compounds
GB8713695D0 (en) * 1987-06-11 1987-07-15 Beecham Group Plc Process
GB8724765D0 (en) * 1987-10-22 1987-11-25 Beecham Group Plc Process
SE8801729D0 (sv) * 1988-05-06 1988-05-06 Astra Ab Purine derivatives for use in therapy
EP0353955A3 (de) * 1988-08-02 1991-08-14 Beecham Group Plc Chemische Verbindungen
DK135489D0 (da) * 1989-03-20 1989-03-20 Gea Farmaceutisk Fabrik As Fremgangsmaade til fremstilling af 9-substituerede guaninderivater og mellemprodukter til brug ved fremgangsmaaden
GB8907173D0 (en) * 1989-03-30 1989-05-10 Beecham Group Plc Novel compounds
GB8912043D0 (en) * 1989-05-25 1989-07-12 Beecham Group Plc Novel compounds
GB8918827D0 (en) * 1989-08-17 1989-09-27 Beecham Group Plc Novel compounds
US5252575A (en) * 1989-08-17 1993-10-12 Beecham Group P.L.C. Antiviral purine derivatives with improved gastrointestinal absorption
GB9107896D0 (en) * 1991-04-13 1991-05-29 Smithkline Beecham Plc Pharmaceuticals
JP2720681B2 (ja) * 1992-01-06 1998-03-04 株式会社村田製作所 移動体の移動検出装置
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
ATE33653T1 (de) * 1982-10-14 1988-05-15 Wellcome Found Antivirale purinderivate.
PT78769A (en) * 1983-06-24 1984-07-01 Merck & Co Inc Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents
IL77298A (en) * 1984-12-12 1999-11-30 Syntex Inc Process for preparing 2-(alkanoyloxymethoxy)-1, 3-propanediols esters and ehers thereof their use in the preparation of (9H-guaninemethoxy)-1, 3-propanediol-derivatives and some new esters and ethers of 2-(alkanoyloxymethoxy)-1, 3-propanediols

Also Published As

Publication number Publication date
AU6644386A (en) 1987-06-18
NZ218598A (en) 1990-10-26
MY101126A (en) 1991-07-31
NO166226B (no) 1991-03-11
NO166226C (no) 1991-06-19
NO865014D0 (no) 1986-12-11
PT83911B (pt) 1989-05-12
DE3650384T2 (de) 1996-06-13
KR880005129A (ko) 1988-06-28
DE3650384D1 (de) 1995-10-12
GR3018105T3 (en) 1996-02-29
ATE127466T1 (de) 1995-09-15
FI865075A7 (fi) 1987-06-14
PL150841B1 (en) 1990-07-31
AU599066B2 (en) 1990-07-12
PL150926B1 (en) 1990-07-31
JPH085886B2 (ja) 1996-01-24
FI85143C (fi) 1992-03-10
EP0242482A3 (en) 1989-02-08
FI85143B (fi) 1991-11-29
DK166823B1 (da) 1993-07-19
PT83911A (en) 1987-01-01
EP0242482A2 (de) 1987-10-28
HU200461B (en) 1990-06-28
HUT43069A (en) 1987-09-28
MA20828A1 (fr) 1987-07-01
PL262930A1 (en) 1988-09-01
PL150925B1 (en) 1990-07-31
PL272031A1 (en) 1989-01-05
PL272032A1 (en) 1989-01-05
JPS62181279A (ja) 1987-08-08
DK595886A (da) 1987-06-14
NO865014L (no) 1987-06-15
DK595886D0 (da) 1986-12-11
ES2076139T3 (es) 1995-11-01
EP0242482B1 (de) 1995-09-06
FI865075A0 (fi) 1986-12-12
KR940010033B1 (ko) 1994-10-21
CA1296726C (en) 1992-03-03

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Legal Events

Date Code Title Description
RH Patent void