IL78317A0 - Phenol derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Phenol derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL78317A0 IL78317A0 IL78317A IL7831786A IL78317A0 IL 78317 A0 IL78317 A0 IL 78317A0 IL 78317 A IL78317 A IL 78317A IL 7831786 A IL7831786 A IL 7831786A IL 78317 A0 IL78317 A0 IL 78317A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- hydrogen
- alkyl
- pharmaceutical compositions
- phenol derivatives
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000002989 phenols Chemical class 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 abstract 1
- 108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 abstract 1
- 238000007239 Wittig reaction Methods 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 150000001502 aryl halides Chemical class 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002534 ethynyl group Chemical class [H]C#C* 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002617 leukotrienes Chemical class 0.000 abstract 1
- 239000002184 metal Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002560 nitrile group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
- C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5428—Acyclic unsaturated phosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- Fixed Capacitors And Capacitor Manufacturing Machines (AREA)
- Emergency Protection Circuit Devices (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853518655 DE3518655A1 (de) | 1985-05-24 | 1985-05-24 | Neue phenolderivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL78317A0 true IL78317A0 (en) | 1986-07-31 |
Family
ID=6271506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL78317A IL78317A0 (en) | 1985-05-24 | 1986-03-28 | Phenol derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US4760087A (el) |
| EP (1) | EP0202529B1 (el) |
| JP (1) | JPH0796507B2 (el) |
| KR (1) | KR930001324B1 (el) |
| AT (1) | ATE48591T1 (el) |
| CA (1) | CA1272723A (el) |
| DD (1) | DD251339A5 (el) |
| DE (2) | DE3518655A1 (el) |
| DK (1) | DK240086A (el) |
| ES (1) | ES8704868A1 (el) |
| FI (1) | FI88708C (el) |
| GR (1) | GR860777B (el) |
| HU (1) | HU196048B (el) |
| IL (1) | IL78317A0 (el) |
| PT (1) | PT82521B (el) |
| SU (1) | SU1591800A3 (el) |
| ZA (1) | ZA862432B (el) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1230859B (it) * | 1989-06-05 | 1991-11-08 | Corvi Camillo Spa | 2 alchinilfenoli sostituiti ad azione anti infiammatoria, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
| DE4120698A1 (de) * | 1991-06-22 | 1992-12-24 | Gruenenthal Gmbh | Substituierte phenoxyalkanole und deren ester, diese verbindungen enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
| US5981591A (en) * | 1992-12-04 | 1999-11-09 | Mayor Pharmaceutical Laboratories, Inc. | Sprayable analgesic composition and method of use |
| US6767925B1 (en) | 1996-10-31 | 2004-07-27 | Joseph A. Deihl | Sprayable analgesic composition and method of use |
| DE19845372A1 (de) * | 1998-10-02 | 2000-04-20 | Gruenenthal Gmbh | Verwendung von Katecholderivaten als Proteinaseninhibitoren |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3033668A (en) * | 1958-03-27 | 1962-05-08 | Dow Chemical Co | Method for inhibiting nitrification of ammonium nitrogen in soil |
| US4393075A (en) * | 1980-04-14 | 1983-07-12 | Takeda Chemical Industries, Ltd. | Quinone compounds and their use in suppressing the production of SRS-A in mammals |
| JPS56150014A (en) * | 1980-04-21 | 1981-11-20 | Takeda Chem Ind Ltd | Antiallergic agent |
| EP0056172B1 (en) * | 1981-01-09 | 1985-04-03 | FISONS plc | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them |
| US4432906A (en) * | 1981-09-14 | 1984-02-21 | Hoffmann-La Roche Inc. | Inhibitors of SRS-synthesis |
| US4499299A (en) * | 1981-12-30 | 1985-02-12 | Ici Americas Inc. | Pharmaceutically active phenylcarboxylic acid derivatives |
| US4497827A (en) * | 1982-08-30 | 1985-02-05 | Syntex (U.S.A.) Inc. | Arachidonic acid analogues as anti-inflammatory and anti-allergic agents |
| EP0123543B1 (en) * | 1983-04-21 | 1988-02-03 | Merck Frosst Canada Inc. | Leukotriene antagonists, their production and use and compositions containing them |
| JPS59204167A (ja) * | 1983-05-02 | 1984-11-19 | Takeda Chem Ind Ltd | ヒドロキノン誘導体およびその製法 |
| US4499295A (en) * | 1983-05-09 | 1985-02-12 | G. D. Searle & Co. | Protease inhibitors |
| SU1424729A3 (ru) * | 1983-05-13 | 1988-09-15 | Яманоути Фармасьютикал Ко,Лтд (Фирма) | Способ получени производных катехина |
| US5105017A (en) * | 1983-07-18 | 1992-04-14 | Eli Lilly And Company | Leukotriene antagonist intermediates |
| CA1242195A (en) * | 1983-07-18 | 1988-09-20 | David K. Herron | Leukotriene antagonists |
| US4590304A (en) * | 1984-03-21 | 1986-05-20 | The United States Of America As Represented By The Secretary Of The Air Force | Protected ethynylated phenols |
| EP0466198A1 (en) * | 1984-05-23 | 1992-01-15 | Green Cross Corporation | A lipoxygenase inhibitor |
| US4564476A (en) * | 1984-10-29 | 1986-01-14 | Mcneilab, Inc. | Aryl fatty acid leukotriene synthesis inhibitors |
| GB8430072D0 (en) * | 1984-11-28 | 1985-01-09 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1985
- 1985-05-24 DE DE19853518655 patent/DE3518655A1/de not_active Withdrawn
-
1986
- 1986-03-26 GR GR860777A patent/GR860777B/el unknown
- 1986-03-28 IL IL78317A patent/IL78317A0/xx not_active IP Right Cessation
- 1986-04-02 CA CA000505690A patent/CA1272723A/en not_active Expired - Fee Related
- 1986-04-02 ZA ZA862432A patent/ZA862432B/xx unknown
- 1986-04-30 ES ES554611A patent/ES8704868A1/es not_active Expired
- 1986-05-05 AT AT86106126T patent/ATE48591T1/de not_active IP Right Cessation
- 1986-05-05 DE DE8686106126T patent/DE3667461D1/de not_active Expired - Fee Related
- 1986-05-05 EP EP86106126A patent/EP0202529B1/de not_active Expired
- 1986-05-06 PT PT82521A patent/PT82521B/pt not_active IP Right Cessation
- 1986-05-07 SU SU864027431A patent/SU1591800A3/ru active
- 1986-05-13 US US06/862,649 patent/US4760087A/en not_active Expired - Lifetime
- 1986-05-21 HU HU862148A patent/HU196048B/hu not_active IP Right Cessation
- 1986-05-22 DD DD86290483A patent/DD251339A5/de not_active IP Right Cessation
- 1986-05-22 DK DK240086A patent/DK240086A/da not_active Application Discontinuation
- 1986-05-23 JP JP61117656A patent/JPH0796507B2/ja not_active Expired - Fee Related
- 1986-05-23 FI FI862184A patent/FI88708C/fi not_active IP Right Cessation
- 1986-05-24 KR KR1019860004098A patent/KR930001324B1/ko not_active IP Right Cessation
-
1988
- 1988-07-14 US US07/218,981 patent/US4959391A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HU196048B (en) | 1988-09-28 |
| ES8704868A1 (es) | 1987-04-16 |
| US4760087A (en) | 1988-07-26 |
| DK240086A (da) | 1986-11-25 |
| ES554611A0 (es) | 1987-04-16 |
| JPH0796507B2 (ja) | 1995-10-18 |
| AU5758186A (en) | 1986-11-27 |
| EP0202529B1 (de) | 1989-12-13 |
| HUT43805A (en) | 1987-12-28 |
| ATE48591T1 (de) | 1989-12-15 |
| DE3667461D1 (de) | 1990-01-18 |
| SU1591800A3 (ru) | 1990-09-07 |
| US4959391A (en) | 1990-09-25 |
| FI88708B (fi) | 1993-03-15 |
| CA1272723A (en) | 1990-08-14 |
| EP0202529A3 (en) | 1988-08-03 |
| JPS61271238A (ja) | 1986-12-01 |
| ZA862432B (en) | 1986-11-26 |
| FI862184A0 (fi) | 1986-05-23 |
| KR860008963A (ko) | 1986-12-19 |
| EP0202529A2 (de) | 1986-11-26 |
| FI88708C (fi) | 1993-06-28 |
| AU587456B2 (en) | 1989-08-17 |
| KR930001324B1 (ko) | 1993-02-26 |
| PT82521B (pt) | 1988-03-03 |
| DK240086D0 (da) | 1986-05-22 |
| DD251339A5 (de) | 1987-11-11 |
| DE3518655A1 (de) | 1986-11-27 |
| FI862184A (fi) | 1986-11-25 |
| GR860777B (en) | 1986-07-18 |
| PT82521A (de) | 1986-06-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES484168A1 (es) | Un procedimiento para preparar 9-(hidroxialcohil)-purinas | |
| IL78317A0 (en) | Phenol derivatives,their preparation and pharmaceutical compositions containing them | |
| ATE56963T1 (de) | Verfahren zur herstellung von aminothiazolessigsaeurederivaten. | |
| ES8303283A2 (es) | Procedimiento para preparar esteres de m-fenoxibencilo de a-cido 2-haloalquil (oxi-,tio-,sulfinil-o sulfonil) fenilalcanoicos. | |
| ES8206535A1 (es) | Un metodo mejorado para producir un compuesto de 7-aminoce- fem. | |
| ES8706646A1 (es) | Procedimiento para preparar derivados de ciclopropano | |
| GB1409321A (en) | Unsaturated esters and their use in insect control | |
| GB2001974A (en) | Vincinic acid derivatives and process for the preparation thereof | |
| ES8204711A1 (es) | Procedimiento de preparacion de derivados difeniletericos | |
| JPS54157560A (en) | Preparation of n-substituted imidazole derivative | |
| ES8300777A1 (es) | Metodo de obtener nuevos compuestos citostaticos del tipo de la vinblastina y similares. | |
| ES8801541A1 (es) | Procedimiento para la obtencion de esteres del acido 4-hidroxilbenzoico con efecto supresor del sebo. | |
| DE2262608A1 (de) | Prostaglandin-derivate und verfahren zu ihrer herstellung | |
| JPS5531011A (en) | Alkali metal salt of cyclobranol succinic acid ester | |
| FR2436146A1 (fr) | Procede de production d'acide ((thienyl-2 carbonyl)-4 phenyl)-2 propionique | |
| JPS55153777A (en) | Improved method of preparation of 3-methyl-3-(substituted phenyl)-glycidic ester | |
| JPS5592342A (en) | Preparation of optically active substituted isovaleric acid | |
| SU1499871A1 (ru) | 4-n-изопропоксифенил-4-аминобутановая кислота в качестве полупродукта для синтеза 5-n-изопропоксифенил-n-карбамоил-2-пирролидона, обладающего транквилизирующей активностью | |
| JPS55139355A (en) | Preparation of optically active thioester and optically active thiol which is derivative thereof | |
| SE8102877L (sv) | Nya 16-amino-prostaglandinderivat jemte sett for deras framstellning | |
| JPS5716844A (en) | Novel aniline derivative and its preparation | |
| JPS54148790A (en) | Ester of pseudomonic acid | |
| JPS5740480A (en) | Preparation of novel vinyl sulfide | |
| JPS55167280A (en) | Zinc compound and its preparation | |
| JPS5538303A (en) | Preparation of phosphoric acid ester |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |