JPS5592342A - Preparation of optically active substituted isovaleric acid - Google Patents
Preparation of optically active substituted isovaleric acidInfo
- Publication number
- JPS5592342A JPS5592342A JP89279A JP89279A JPS5592342A JP S5592342 A JPS5592342 A JP S5592342A JP 89279 A JP89279 A JP 89279A JP 89279 A JP89279 A JP 89279A JP S5592342 A JPS5592342 A JP S5592342A
- Authority
- JP
- Japan
- Prior art keywords
- isovaleric acid
- acid
- optically active
- substituted
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To prepare an optically active substituted isovaleric acid having excellent insecticidal activity as the acid component of a pyrethroid insecticide and having a high optical purity, by reacting a substituted isovaleric acid with an optically active α-phenyl-ethylamine, and resolving the products taking advantage of the solubility difference.
CONSTITUTION: A substituted isovaleric acid expressed by the formula (R is H, methyl or Cl), e.g. (±)-α-(p-chlorophenoxy)isovaleric acid, etc., is reacted with the equimolar amount of (+)-α-phenyl-ethylamine to give the salt, from which the crystal of the (+)-α-phenyl-ethylamine salt of the (+)-substituted isovaleric acid is obtained by using an organic solvent, e.g. n-hexane, benzene, etc. The crystal is decomposed with an alkali or a mineral acid and extracted with an organic solvent. The water layer is decomposed with an acid or an alkali and extracted with an organic solvent to give the optically active substituted isovaleric acid, e.g. (+)-α-(p-chlorophenoxy)-isovaleric acid, etc.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP89279A JPS5592342A (en) | 1979-01-06 | 1979-01-06 | Preparation of optically active substituted isovaleric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP89279A JPS5592342A (en) | 1979-01-06 | 1979-01-06 | Preparation of optically active substituted isovaleric acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5592342A true JPS5592342A (en) | 1980-07-12 |
| JPS6213338B2 JPS6213338B2 (en) | 1987-03-25 |
Family
ID=11486322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP89279A Granted JPS5592342A (en) | 1979-01-06 | 1979-01-06 | Preparation of optically active substituted isovaleric acid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5592342A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0395138A (en) * | 1989-09-07 | 1991-04-19 | Nissan Chem Ind Ltd | Optical resolution of 3-methylheptanoic acid |
-
1979
- 1979-01-06 JP JP89279A patent/JPS5592342A/en active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0395138A (en) * | 1989-09-07 | 1991-04-19 | Nissan Chem Ind Ltd | Optical resolution of 3-methylheptanoic acid |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6213338B2 (en) | 1987-03-25 |
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