JPS54148790A - Ester of pseudomonic acid - Google Patents
Ester of pseudomonic acidInfo
- Publication number
- JPS54148790A JPS54148790A JP5643178A JP5643178A JPS54148790A JP S54148790 A JPS54148790 A JP S54148790A JP 5643178 A JP5643178 A JP 5643178A JP 5643178 A JP5643178 A JP 5643178A JP S54148790 A JPS54148790 A JP S54148790A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- pseudomonic acid
- ester
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I: (R1 is, lower alkyl, or aryl group; R2 is OH, lower alkoxy, aralkyloxy group, etc.; n is an integer 0W3).
EXAMPLE: Pseudomonic acid methoxycarbonylmethyl ester.
USE: Antibacterials effective against Gram-positive, penicillin- and macrolide resistant bacteria for a long duration, and administrable orally.
PROCESS: Pseudomonic acid of formula II, its salt, or reactive derivative is reacted with an alcohol of formula III or its reactive derivative to give the compound of formula I. The compound of formula I wherein R2 is aralkyloxy group is subjected to catalytic hydrogenolysis to give a compound of formula I wherein R2 is OH, if necessary.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5643178A JPS54148790A (en) | 1978-05-11 | 1978-05-11 | Ester of pseudomonic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5643178A JPS54148790A (en) | 1978-05-11 | 1978-05-11 | Ester of pseudomonic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS54148790A true JPS54148790A (en) | 1979-11-21 |
Family
ID=13026892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5643178A Pending JPS54148790A (en) | 1978-05-11 | 1978-05-11 | Ester of pseudomonic acid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS54148790A (en) |
-
1978
- 1978-05-11 JP JP5643178A patent/JPS54148790A/en active Pending
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