IL78161A0 - Insulin derivatives and pharmaceutical preparations containing them - Google Patents

Insulin derivatives and pharmaceutical preparations containing them

Info

Publication number
IL78161A0
IL78161A0 IL78161A IL7816186A IL78161A0 IL 78161 A0 IL78161 A0 IL 78161A0 IL 78161 A IL78161 A IL 78161A IL 7816186 A IL7816186 A IL 7816186A IL 78161 A0 IL78161 A0 IL 78161A0
Authority
IL
Israel
Prior art keywords
insulin derivatives
pct
pharmaceutical preparations
preparations containing
sec
Prior art date
Application number
IL78161A
Other languages
English (en)
Original Assignee
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte
Publication of IL78161A0 publication Critical patent/IL78161A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL78161A 1985-03-15 1986-03-14 Insulin derivatives and pharmaceutical preparations containing them IL78161A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat

Publications (1)

Publication Number Publication Date
IL78161A0 true IL78161A0 (en) 1986-07-31

Family

ID=8102063

Family Applications (2)

Application Number Title Priority Date Filing Date
IL78161A IL78161A0 (en) 1985-03-15 1986-03-14 Insulin derivatives and pharmaceutical preparations containing them
IL78160A IL78160A (en) 1985-03-15 1986-03-14 Insulin derivatives and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL78160A IL78160A (en) 1985-03-15 1986-03-14 Insulin derivatives and pharmaceutical preparations containing them

Country Status (11)

Country Link
US (1) US5028586A (da)
EP (2) EP0216833B1 (da)
JP (2) JPS62502538A (da)
AT (2) ATE84546T1 (da)
AU (2) AU5622686A (da)
DE (2) DE3673737D1 (da)
DK (3) DK119785D0 (da)
FI (2) FI864559A0 (da)
IL (2) IL78161A0 (da)
NO (2) NO174278C (da)
WO (2) WO1986005497A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
JP2606915B2 (ja) * 1987-02-25 1997-05-07 ノボ ノルディスク アクティーゼルスカブ 新規インシュリン誘導体
BR8803346A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
BR8803345A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
JPH03506023A (ja) * 1988-07-20 1991-12-26 ノボ ノルデイスク アクツイエセルスカプ ポリペプチド
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
WO1992010284A2 (en) 1990-12-07 1992-06-25 Cnc Development, Inc. Catalytic chemical reactor
DK33591D0 (da) * 1991-02-27 1991-02-27 Novo Nordisk As
WO1992020367A1 (en) * 1991-05-24 1992-11-26 Amylin Pharmaceuticals, Inc. Treatment of anorexia and related states
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
CA2503723A1 (en) * 2002-11-01 2004-05-21 Antares Pharma, Inc. Administration of insulin by jet injection
EP2842576B1 (en) 2004-01-21 2017-06-28 Novo Nordisk Health Care AG Transglutaminase mediated conjugation of peptides
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
EP1991575A1 (en) * 2006-02-21 2008-11-19 Novo Nordisk A/S Single-chain insulin analogues and pharmaceutical formulations thereof
CA2713348C (en) * 2008-01-30 2018-10-09 Indiana University Research And Technology Corporation Ester-based peptide prodrugs
AR074811A1 (es) 2008-12-19 2011-02-16 Univ Indiana Res & Tech Corp Profarmaco de peptido de la superfamilia de glucagon basados en amida
KR20110114568A (ko) * 2008-12-19 2011-10-19 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 디펩티드 링크된 약효 물질
JP5912112B2 (ja) 2010-06-24 2016-04-27 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation アミド系インスリンプロドラッグ
CN104114183A (zh) 2011-12-20 2014-10-22 印第安纳大学研究及科技有限公司 用于治疗糖尿病的基于ctp的胰岛素类似物
JP6387008B2 (ja) 2012-09-26 2018-09-05 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation インスリンアナローグダイマー
AU2014241743B2 (en) 2013-03-14 2018-07-05 Indiana University Research And Technology Corporation Insulin-incretin conjugates
EP3206710B1 (en) 2014-09-24 2020-05-06 Indiana University Research & Technology Corporation Incretin-insulin conjugates
EP3197912B1 (en) 2014-09-24 2023-01-04 Indiana University Research & Technology Corporation Lipidated amide-based insulin prodrugs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider

Also Published As

Publication number Publication date
EP0216832A1 (en) 1987-04-08
DE3673737D1 (de) 1990-10-04
FI93460C (fi) 1995-04-10
WO1986005496A1 (en) 1986-09-25
AU5622786A (en) 1986-10-13
EP0216833B1 (en) 1993-01-13
DK545786A (da) 1986-11-14
IL78160A (en) 1991-06-10
IL78160A0 (en) 1986-07-31
NO864555L (no) 1986-11-14
DK545686A (da) 1986-11-14
AU596968B2 (en) 1990-05-24
DK545786D0 (da) 1986-11-14
DE3687500T2 (de) 1993-07-01
NO864555D0 (no) 1986-11-14
NO174278B (no) 1994-01-03
NO864556L (no) 1986-11-14
EP0216832B1 (en) 1990-08-29
DE3687500D1 (de) 1993-02-25
DK545686D0 (da) 1986-11-14
ATE84546T1 (de) 1993-01-15
EP0216833A1 (en) 1987-04-08
DK119785D0 (da) 1985-03-15
DK159856C (da) 1991-05-06
US5028586A (en) 1991-07-02
WO1986005497A1 (en) 1986-09-25
FI93460B (fi) 1994-12-30
JPS62502196A (ja) 1987-08-27
ATE56022T1 (de) 1990-09-15
FI864559A (fi) 1986-11-10
NO864556D0 (no) 1986-11-14
AU5622686A (en) 1986-10-13
FI864560A (fi) 1986-11-10
FI864560A0 (fi) 1986-11-10
FI864559A0 (fi) 1986-11-10
DK159856B (da) 1990-12-17
JPS62502538A (ja) 1987-10-01
NO174278C (no) 1994-04-13

Similar Documents

Publication Publication Date Title
IL78161A0 (en) Insulin derivatives and pharmaceutical preparations containing them
IL91404A0 (en) Substituted 4-azatricyclo(22.3.1.0 4,9)octacos-18-ene derivations,their preparation and pharmaceutical compositions containing them
IL84446A0 (en) 3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
NZ215866A (en) 2,5-di(aryl/heterocyclyl) tetrahydro-furans and pharmaceutical compositions
AR243180A1 (es) Procedimiento para la obtencion de 3,4-dihidro-2h-benzopiranos sustituidos.
IL92268A0 (en) 14alpha,17alpha,ethanoestratriene derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
DE3662520D1 (en) Cis-1,3,5-triamino 2,4,6-cyclohexanetriol derivatives, their use, process for their preparation and pharmaceutical preparations containing them
EP0264953A3 (en) Amino acid preparations containing n,n'-bis-l-amino acid-l-cystin peptides for oral and parenteral use
EP0588177A3 (en) An interferon-alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
DK578589A (da) Farmaceutisk praeparat indeholdende labdanterpenoidderivater og pyrimido(6,1-a)isoquinolin-4-onderivater, dets fremstilling og anvendelse
EP0234348A3 (en) N-glycosyl amide derivatives, method for their preparation and their use as medicaments
IL79933A0 (en) (+)-6-chloro-5,10-dihydro-5-((1-methyl-4-piperidinyl)-acetyl)-11h-dibenzo(b,e)(1,4)diazepin-11-one and its acid addition salts,their preparation and pharmaceutical compositions containing them
IL78538A0 (en) (-)-1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,7,12,12b alpha-octahydroindolo(2,3-a)-quinolizine,its preparation and pharmaceutical compositions containing them
IL90187A0 (en) Method for treating an auto-immune disease using succinyl-acetone and pharmaceutical compositions containing the same
DE3671630D1 (de) Glycero-3(2)-phospho-l-serinderivate und diese enthaltende pharmazeutischen praeparate.
IL90191A0 (en) 3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA86659B (en) 6-chloro-3-methyl-1h-2,3,4,5-tetrahydro-3-benzazepine-n-oxide and medical compositions using it
NZ216246A (en) 2-azabicyclo(3.3.0 -7-octene-3-carboxylic acid derivatives and pharmaceutical compositions
McPhalen X-ray crystallographic studies on subtilisins and their protein inhibitors
Hage Soft drink industry.(c1985)
ATE53214T1 (de) Glycero-3(2)-phospho-l-serinderivate und diese enthaltende pharmazeutischen praeparate.