FI93460B - Menetelmä uusien insuliinijohdannaisten valmistamiseksi - Google Patents

Menetelmä uusien insuliinijohdannaisten valmistamiseksi

Info

Publication number
FI93460B
FI93460B FI864560A FI864560A FI93460B FI 93460 B FI93460 B FI 93460B FI 864560 A FI864560 A FI 864560A FI 864560 A FI864560 A FI 864560A FI 93460 B FI93460 B FI 93460B
Authority
FI
Finland
Prior art keywords
insulin derivatives
pct
preparation
new insulin
sec
Prior art date
Application number
FI864560A
Other languages
English (en)
Swedish (sv)
Other versions
FI93460C (fi
FI864560A0 (fi
FI864560A (fi
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI864560A0 publication Critical patent/FI864560A0/fi
Publication of FI864560A publication Critical patent/FI864560A/fi
Application granted granted Critical
Publication of FI93460B publication Critical patent/FI93460B/fi
Publication of FI93460C publication Critical patent/FI93460C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI864560A 1985-03-15 1986-11-10 Menetelmä uusien insuliinijohdannaisten valmistamiseksi FI93460C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
PCT/DK1986/000023 WO1986005497A1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives

Publications (4)

Publication Number Publication Date
FI864560A0 FI864560A0 (fi) 1986-11-10
FI864560A FI864560A (fi) 1986-11-10
FI93460B true FI93460B (fi) 1994-12-30
FI93460C FI93460C (fi) 1995-04-10

Family

ID=8102063

Family Applications (2)

Application Number Title Priority Date Filing Date
FI864559A FI864559A (fi) 1985-03-15 1986-11-10 Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat.
FI864560A FI93460C (fi) 1985-03-15 1986-11-10 Menetelmä uusien insuliinijohdannaisten valmistamiseksi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI864559A FI864559A (fi) 1985-03-15 1986-11-10 Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat.

Country Status (11)

Country Link
US (1) US5028586A (fi)
EP (2) EP0216832B1 (fi)
JP (2) JPS62502196A (fi)
AT (2) ATE56022T1 (fi)
AU (2) AU596968B2 (fi)
DE (2) DE3687500T2 (fi)
DK (3) DK119785D0 (fi)
FI (2) FI864559A (fi)
IL (2) IL78160A (fi)
NO (2) NO174278C (fi)
WO (2) WO1986005497A1 (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE10075034I1 (de) * 1987-02-25 2001-05-23 Novo Nordisk As Insulinderivate
BR8803345A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
BR8803346A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
AU616205B2 (en) * 1988-07-20 1991-10-24 Novo Nordisk A/S Human insulin analogs and preparations containing them
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
WO1992010284A2 (en) 1990-12-07 1992-06-25 Cnc Development, Inc. Catalytic chemical reactor
DK33591D0 (fi) * 1991-02-27 1991-02-27 Novo Nordisk As
DE69221725T2 (de) * 1991-05-24 1997-12-18 Amylin Pharmaceuticals, Inc., San Diego, Calif. Amylin oder amylinanaloga enthaltende zusammensetzung, welche auch wahlweise insulin enthält, zur behandlung von anorexie und verwandten zuständen
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
AU2003209111A1 (en) * 2002-11-01 2004-06-07 Antares Pharma, Inc. Administration of insulin by jet injection
CA2552043A1 (en) 2004-01-21 2005-08-04 Novo Nordisk A/S Transglutaminase mediated conjugation of peptides
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
JP2009527526A (ja) * 2006-02-21 2009-07-30 ノボ・ノルデイスク・エー／エス 単鎖インスリンのアナログとその製薬的製剤
WO2009099763A1 (en) * 2008-01-30 2009-08-13 Indiana University Research And Technology Corporation Ester-based peptide prodrugs
CA2747195A1 (en) * 2008-12-19 2010-07-15 Indiana University Research And Technology Corporation Dipeptide linked medicinal agents
WO2010071807A1 (en) 2008-12-19 2010-06-24 Indiana University Research And Technology Corporation Amide based glucagon superfamily peptide prodrugs
US8946147B2 (en) 2010-06-24 2015-02-03 Indiana University Research And Technology Corporation Amide-based insulin prodrugs
BR112014015156A2 (pt) 2011-12-20 2020-10-27 Indiana University Research And Technology Corporation análogos de insulina à base de ctp, seus métodos de produção e uso no tratamento de hiperglicemia, bem como sequência de ácido nucleico e célula hospedeira
WO2014052451A2 (en) 2012-09-26 2014-04-03 Indiana University Research And Technology Corporation Insulin analog dimers
KR20150131213A (ko) 2013-03-14 2015-11-24 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 인슐린-인크레틴 접합체들
JP6701208B2 (ja) 2014-09-24 2020-05-27 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 脂質化アミド系インスリンプロドラッグ
EP3206710B1 (en) 2014-09-24 2020-05-06 Indiana University Research & Technology Corporation Incretin-insulin conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider

Also Published As

Publication number Publication date
DK545686D0 (da) 1986-11-14
EP0216833B1 (en) 1993-01-13
DK119785D0 (da) 1985-03-15
DK545786A (da) 1986-11-14
EP0216832A1 (en) 1987-04-08
FI93460C (fi) 1995-04-10
IL78160A (en) 1991-06-10
IL78160A0 (en) 1986-07-31
FI864560A0 (fi) 1986-11-10
NO864555D0 (no) 1986-11-14
ATE56022T1 (de) 1990-09-15
DE3687500D1 (de) 1993-02-25
DE3687500T2 (de) 1993-07-01
FI864559A0 (fi) 1986-11-10
ATE84546T1 (de) 1993-01-15
DE3673737D1 (de) 1990-10-04
DK545686A (da) 1986-11-14
AU596968B2 (en) 1990-05-24
IL78161A0 (en) 1986-07-31
US5028586A (en) 1991-07-02
AU5622686A (en) 1986-10-13
NO864556D0 (no) 1986-11-14
WO1986005497A1 (en) 1986-09-25
JPS62502538A (ja) 1987-10-01
NO174278C (no) 1994-04-13
EP0216832B1 (en) 1990-08-29
FI864560A (fi) 1986-11-10
NO864555L (no) 1986-11-14
AU5622786A (en) 1986-10-13
DK159856C (da) 1991-05-06
DK159856B (da) 1990-12-17
JPS62502196A (ja) 1987-08-27
FI864559A (fi) 1986-11-10
NO174278B (no) 1994-01-03
EP0216833A1 (en) 1987-04-08
DK545786D0 (da) 1986-11-14
NO864556L (no) 1986-11-14
WO1986005496A1 (en) 1986-09-25

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: NOVO NORDISK A/S