ATE84546T1 - Insulinabkoemmlinge und arzneimittel die diese enthalten. - Google Patents

Insulinabkoemmlinge und arzneimittel die diese enthalten.

Info

Publication number
ATE84546T1
ATE84546T1 AT86901827T AT86901827T ATE84546T1 AT E84546 T1 ATE84546 T1 AT E84546T1 AT 86901827 T AT86901827 T AT 86901827T AT 86901827 T AT86901827 T AT 86901827T AT E84546 T1 ATE84546 T1 AT E84546T1
Authority
AT
Austria
Prior art keywords
pct
insulin
combatives
medicines containing
sec
Prior art date
Application number
AT86901827T
Other languages
English (en)
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE84546T1 publication Critical patent/ATE84546T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT86901827T 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten. ATE84546T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
EP86901827A EP0216833B1 (de) 1985-03-15 1986-03-14 Insulinabkömmlinge und arzneimittel die diese enthalten
PCT/DK1986/000023 WO1986005497A1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives

Publications (1)

Publication Number Publication Date
ATE84546T1 true ATE84546T1 (de) 1993-01-15

Family

ID=8102063

Family Applications (2)

Application Number Title Priority Date Filing Date
AT86901826T ATE56022T1 (de) 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten.
AT86901827T ATE84546T1 (de) 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT86901826T ATE56022T1 (de) 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten.

Country Status (11)

Country Link
US (1) US5028586A (de)
EP (2) EP0216832B1 (de)
JP (2) JPS62502196A (de)
AT (2) ATE56022T1 (de)
AU (2) AU5622686A (de)
DE (2) DE3673737D1 (de)
DK (3) DK119785D0 (de)
FI (2) FI93460C (de)
IL (2) IL78160A (de)
NO (2) NO174278C (de)
WO (2) WO1986005496A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
JP2606915B2 (ja) * 1987-02-25 1997-05-07 ノボ ノルディスク アクティーゼルスカブ 新規インシュリン誘導体
BR8803345A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
BR8803346A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
KR900701842A (ko) * 1988-07-20 1990-12-04 헨리 브뢰늄 인간 인슐린 동족체와 그를 포함하는 제제
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
WO1992010284A2 (en) 1990-12-07 1992-06-25 Cnc Development, Inc. Catalytic chemical reactor
DK33591D0 (de) * 1991-02-27 1991-02-27 Novo Nordisk As
DK0586589T3 (da) * 1991-05-24 1997-09-22 Amylin Pharmaceuticals Inc Amylin- eller amylinanalogpræparat, som eventuelt indeholder insulin, til behandling af anoreksi og beslægtede tilstande
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
JP2006504482A (ja) * 2002-11-01 2006-02-09 アンタレス・ファーマ・インコーポレーテッド 噴射式注射によるインスリン投薬
DK2842576T3 (en) 2004-01-21 2017-10-16 Novo Nordisk Healthcare Ag Transglutaminase-mediated peptide conjugation
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
JP2009527526A (ja) * 2006-02-21 2009-07-30 ノボ・ノルデイスク・エー／エス 単鎖インスリンのアナログとその製薬的製剤
WO2009099763A1 (en) * 2008-01-30 2009-08-13 Indiana University Research And Technology Corporation Ester-based peptide prodrugs
CN102300580A (zh) * 2008-12-19 2011-12-28 印第安纳大学研究及科技有限公司 二肽连接的药剂
TWI489992B (zh) 2008-12-19 2015-07-01 印地安那大學研究及技術公司 醯胺系胰高血糖素超級家族之胜肽前驅藥物
JP5912112B2 (ja) 2010-06-24 2016-04-27 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ アミド系インスリンプロドラッグ
BR112014015156A2 (pt) 2011-12-20 2020-10-27 Indiana University Research And Technology Corporation análogos de insulina à base de ctp, seus métodos de produção e uso no tratamento de hiperglicemia, bem como sequência de ácido nucleico e célula hospedeira
CN108383902A (zh) 2012-09-26 2018-08-10 印第安纳大学研究及科技有限公司 胰岛素类似物二聚体
KR20150131213A (ko) 2013-03-14 2015-11-24 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 인슐린-인크레틴 접합체들
US10232020B2 (en) 2014-09-24 2019-03-19 Indiana University Research And Technology Corporation Incretin-insulin conjugates
ES2947409T3 (es) 2014-09-24 2023-08-08 Univ Indiana Res & Tech Corp Profármacos de insulina a base de amida lipídica

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
EP0017938B1 (de) * 1979-04-13 1983-08-03 Shionogi & Co., Ltd. Verfahren zur Herstellung von B30-Threonin-Insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider

Also Published As

Publication number Publication date
FI864559A0 (fi) 1986-11-10
DK545686A (da) 1986-11-14
FI93460C (fi) 1995-04-10
NO864556L (no) 1986-11-14
IL78160A0 (en) 1986-07-31
NO864555L (no) 1986-11-14
DK119785D0 (da) 1985-03-15
EP0216833B1 (de) 1993-01-13
FI864560A0 (fi) 1986-11-10
JPS62502196A (ja) 1987-08-27
JPS62502538A (ja) 1987-10-01
NO174278C (no) 1994-04-13
EP0216832A1 (de) 1987-04-08
NO174278B (no) 1994-01-03
DK159856B (da) 1990-12-17
DK545786D0 (da) 1986-11-14
AU596968B2 (en) 1990-05-24
WO1986005496A1 (en) 1986-09-25
EP0216833A1 (de) 1987-04-08
AU5622686A (en) 1986-10-13
FI864559A (fi) 1986-11-10
ATE56022T1 (de) 1990-09-15
DK545786A (da) 1986-11-14
DE3687500D1 (de) 1993-02-25
US5028586A (en) 1991-07-02
NO864555D0 (no) 1986-11-14
EP0216832B1 (de) 1990-08-29
DE3687500T2 (de) 1993-07-01
DK545686D0 (da) 1986-11-14
NO864556D0 (no) 1986-11-14
DE3673737D1 (de) 1990-10-04
IL78160A (en) 1991-06-10
FI864560A (fi) 1986-11-10
AU5622786A (en) 1986-10-13
WO1986005497A1 (en) 1986-09-25
DK159856C (da) 1991-05-06
IL78161A0 (en) 1986-07-31
FI93460B (fi) 1994-12-30

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Legal Events

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REN Ceased due to non-payment of the annual fee