DE3676097D1 - 15(r)-5-fluorprostazykline und diese verbindungen enthaltende arzneimittel. - Google Patents
15(r)-5-fluorprostazykline und diese verbindungen enthaltende arzneimittel.Info
- Publication number
- DE3676097D1 DE3676097D1 DE8686102559T DE3676097T DE3676097D1 DE 3676097 D1 DE3676097 D1 DE 3676097D1 DE 8686102559 T DE8686102559 T DE 8686102559T DE 3676097 T DE3676097 T DE 3676097T DE 3676097 D1 DE3676097 D1 DE 3676097D1
- Authority
- DE
- Germany
- Prior art keywords
- fluoroprostacycline
- compounds
- products containing
- medicinal products
- medicinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/706,806 US4616034A (en) | 1985-02-28 | 1985-02-28 | 15(R)-5-fluoroprostacyclins, pharmaceutical compositions and anti-thrombotic method of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3676097D1 true DE3676097D1 (de) | 1991-01-24 |
Family
ID=24839120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686102559T Expired - Fee Related DE3676097D1 (de) | 1985-02-28 | 1986-02-27 | 15(r)-5-fluorprostazykline und diese verbindungen enthaltende arzneimittel. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4616034A (de) |
EP (1) | EP0193194B1 (de) |
JP (1) | JPS61205271A (de) |
AU (1) | AU5412886A (de) |
DE (1) | DE3676097D1 (de) |
ZA (1) | ZA861476B (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4719220A (en) * | 1985-02-28 | 1988-01-12 | G. D. Searle & Co. | 15(R)-5-fluoroprostacyclins, pharmaceutical compositions and anti-thrombotic methods of use thereof |
US4808734A (en) * | 1986-12-01 | 1989-02-28 | Hoffmann-La Roche Inc. | 16-cycloalkyl-7-fluoro-prostacyclins |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4178367A (en) * | 1977-02-21 | 1979-12-11 | Ono Pharmaceutical Co. Ltd. | Prostaglandin I2 analogues |
IT1088036B (it) * | 1977-11-25 | 1985-06-04 | Erba Carlo Spa | 15-epi-prostaciclina e prostaciclina analoghi |
US4324730A (en) * | 1979-10-10 | 1982-04-13 | The University Of Chicago | Certain fluorine substituted PGI2 compounds |
WO1981001002A1 (en) * | 1979-10-10 | 1981-04-16 | Univ Chicago | Fluoro-substituted prostaglandins and prostacyclins |
US4472428A (en) * | 1980-12-09 | 1984-09-18 | Teijin Limited | Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore |
EP0062303B1 (de) * | 1981-04-02 | 1985-11-27 | G.D. Searle & Co. | 5-Fluor-PGI-Derivate |
US4540801A (en) * | 1981-04-02 | 1985-09-10 | G. D. Searle & Co. | 5 Fluoro PGI compounds |
JPS58150583A (ja) * | 1982-03-04 | 1983-09-07 | Teijin Ltd | 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物 |
-
1985
- 1985-02-28 US US06/706,806 patent/US4616034A/en not_active Expired - Fee Related
-
1986
- 1986-02-27 DE DE8686102559T patent/DE3676097D1/de not_active Expired - Fee Related
- 1986-02-27 EP EP86102559A patent/EP0193194B1/de not_active Expired - Lifetime
- 1986-02-27 JP JP61042793A patent/JPS61205271A/ja active Pending
- 1986-02-27 ZA ZA861476A patent/ZA861476B/xx unknown
- 1986-02-27 AU AU54128/86A patent/AU5412886A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US4616034A (en) | 1986-10-07 |
EP0193194B1 (de) | 1990-12-12 |
EP0193194A2 (de) | 1986-09-03 |
ZA861476B (en) | 1987-05-27 |
AU5412886A (en) | 1986-09-04 |
EP0193194A3 (en) | 1987-09-02 |
JPS61205271A (ja) | 1986-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |