FI864560A0 - Menetelmä uusien insuliinijohdannaisten valmistamiseksi - Google Patents

Menetelmä uusien insuliinijohdannaisten valmistamiseksi

Info

Publication number
FI864560A0
FI864560A0 FI864560A FI864560A FI864560A0 FI 864560 A0 FI864560 A0 FI 864560A0 FI 864560 A FI864560 A FI 864560A FI 864560 A FI864560 A FI 864560A FI 864560 A0 FI864560 A0 FI 864560A0
Authority
FI
Finland
Prior art keywords
insulin derivatives
pct
procedure
preparation
new insulin
Prior art date
Application number
FI864560A
Other languages
English (en)
Swedish (sv)
Other versions
FI93460C (fi
FI93460B (fi
FI864560A (fi
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte
Publication of FI864560A0 publication Critical patent/FI864560A0/fi
Publication of FI864560A publication Critical patent/FI864560A/fi
Application granted granted Critical
Publication of FI93460B publication Critical patent/FI93460B/fi
Publication of FI93460C publication Critical patent/FI93460C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI864560A 1985-03-15 1986-11-10 Menetelmä uusien insuliinijohdannaisten valmistamiseksi FI93460C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
PCT/DK1986/000023 WO1986005497A1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives

Publications (4)

Publication Number Publication Date
FI864560A0 true FI864560A0 (fi) 1986-11-10
FI864560A FI864560A (fi) 1986-11-10
FI93460B FI93460B (fi) 1994-12-30
FI93460C FI93460C (fi) 1995-04-10

Family

ID=8102063

Family Applications (2)

Application Number Title Priority Date Filing Date
FI864560A FI93460C (fi) 1985-03-15 1986-11-10 Menetelmä uusien insuliinijohdannaisten valmistamiseksi
FI864559A FI864559A (fi) 1985-03-15 1986-11-10 Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI864559A FI864559A (fi) 1985-03-15 1986-11-10 Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat.

Country Status (11)

Country Link
US (1) US5028586A (fi)
EP (2) EP0216833B1 (fi)
JP (2) JPS62502538A (fi)
AT (2) ATE84546T1 (fi)
AU (2) AU5622686A (fi)
DE (2) DE3687500T2 (fi)
DK (3) DK119785D0 (fi)
FI (2) FI93460C (fi)
IL (2) IL78160A (fi)
NO (2) NO864555D0 (fi)
WO (2) WO1986005497A1 (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
CA1339416C (en) * 1987-02-25 1997-09-02 Liselotte Langkjaer Insulin derivatives
BR8803345A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
BR8803346A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
ATE93238T1 (de) * 1988-07-20 1993-09-15 Novo Nordisk As Menschliche insulinanalage und zubereitungen daraus.
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
AU9172991A (en) 1990-12-07 1992-07-08 Cnc Development, Inc. Catalytic chemical reactor
DK33591D0 (fi) * 1991-02-27 1991-02-27 Novo Nordisk As
SG49239A1 (en) * 1991-05-24 1998-05-18 Amylin Pharmaceuticals Inc Amylin and possibly insulin containing composition for the treatment of aneroxia and related states
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
KR20050075373A (ko) * 2002-11-01 2005-07-20 앤태어스 파머, 인코퍼레이티드 분사식 주사에 의한 인슐린 투여
ATE550041T1 (de) 2004-01-21 2012-04-15 Novo Nordisk Healthcare Ag Transglutaminase-vermittelte konjugation von peptiden
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
US20090069216A1 (en) * 2006-02-21 2009-03-12 Novo Nordisk A/S Single-Chain Insulin Analogues and Pharmaceutical Formulations Thereof
WO2009099763A1 (en) * 2008-01-30 2009-08-13 Indiana University Research And Technology Corporation Ester-based peptide prodrugs
AR074811A1 (es) 2008-12-19 2011-02-16 Univ Indiana Res & Tech Corp Profarmaco de peptido de la superfamilia de glucagon basados en amida
EP2376098A4 (en) * 2008-12-19 2014-06-11 Univ Indiana Res & Tech Corp DIPEPTIDE-LINKED MEDICAL AGENTS
EP2585102B1 (en) 2010-06-24 2015-05-06 Indiana University Research and Technology Corporation Amide-based insulin prodrugs
US9573987B2 (en) 2011-12-20 2017-02-21 Indiana University Research And Technology Corporation CTP-based insulin analogs for treatment of diabetes
AU2013323669B2 (en) 2012-09-26 2018-03-01 Indiana University Research And Technology Corporation Insulin analog dimers
AU2014241743B2 (en) 2013-03-14 2018-07-05 Indiana University Research And Technology Corporation Insulin-incretin conjugates
US10385107B2 (en) 2014-09-24 2019-08-20 Indiana Univeresity Researc and Technology Corporation Lipidated amide-based insulin prodrugs
US10232020B2 (en) 2014-09-24 2019-03-19 Indiana University Research And Technology Corporation Incretin-insulin conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
DE3064479D1 (en) * 1979-04-13 1983-09-08 Shionogi & Co Process for preparing a b30-threonine insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider

Also Published As

Publication number Publication date
EP0216832A1 (en) 1987-04-08
DK545786D0 (da) 1986-11-14
ATE84546T1 (de) 1993-01-15
AU596968B2 (en) 1990-05-24
NO864556D0 (no) 1986-11-14
DK159856C (da) 1991-05-06
WO1986005497A1 (en) 1986-09-25
IL78160A0 (en) 1986-07-31
NO864555L (no) 1986-11-14
NO864556L (no) 1986-11-14
DK545686A (da) 1986-11-14
FI864559A0 (fi) 1986-11-10
EP0216832B1 (en) 1990-08-29
DE3673737D1 (de) 1990-10-04
WO1986005496A1 (en) 1986-09-25
US5028586A (en) 1991-07-02
DE3687500D1 (de) 1993-02-25
AU5622786A (en) 1986-10-13
JPS62502538A (ja) 1987-10-01
NO174278C (no) 1994-04-13
ATE56022T1 (de) 1990-09-15
NO864555D0 (no) 1986-11-14
NO174278B (no) 1994-01-03
AU5622686A (en) 1986-10-13
EP0216833B1 (en) 1993-01-13
EP0216833A1 (en) 1987-04-08
DK119785D0 (da) 1985-03-15
JPS62502196A (ja) 1987-08-27
DK545786A (da) 1986-11-14
FI93460C (fi) 1995-04-10
IL78160A (en) 1991-06-10
FI93460B (fi) 1994-12-30
FI864559A (fi) 1986-11-10
IL78161A0 (en) 1986-07-31
DK545686D0 (da) 1986-11-14
DE3687500T2 (de) 1993-07-01
FI864560A (fi) 1986-11-10
DK159856B (da) 1990-12-17

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Legal Events

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MM Patent lapsed
MM Patent lapsed

Owner name: NOVO NORDISK A/S